Who owns Xenon Pharmaceuticals (XENE)
Which tracked institutional funds hold XENE, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See XENE company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
111 tracked funds added or opened XENE while 65 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
XENE’s largest tracked holder by dollar value, FMR LLC, sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 0.0pp gap the other way — the median holder sizes XENE more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in XENE divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 302 tracked filers holding XENE, 171 increased or opened the position and 122 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in XENE between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 19
- Jupiter Topco LLC$253M
- MARSHALL WACE, LLP$42M
- PANAGORA ASSET MANAGEMENT INC$40M
- Jones Hill Capital LP$22M
- Man Group plc$19M
- Squarepoint Ops LLC$7M
Full exits 24
- JANUS HENDERSON GROUP PLC$243M
- Holocene Advisors, LP$88M
- T. Rowe Price Investment Management, Inc.$55M
- Commodore Capital LP$48M
- MPM BIOIMPACT LLC$34M
- Sofinnova Investments, Inc.$18M
Largest adds
- BlackRock, Inc.$247M
- PRICE T ROWE ASSOCIATES INC /MD/$119M
- TWO SIGMA INVESTMENTS, LP$64M
- Invesco Ltd.$51M
- JPMORGAN CHASE & CO$51M
- Nuveen, LLC$45M
Largest trims
- WELLINGTON MANAGEMENT GROUP LLP$194M
- CITADEL ADVISORS LLC$70M
- JENNISON ASSOCIATES LLC$64M
- FMR LLC$47M
- Alyeska Investment Group, L.P.$33M
- Caligan Partners LP$27M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| FMR LLC trimmed | 9,647,998 | $582M | 10.2% | 2026-Q2 |
| BlackRock, Inc. added | 7,522,482 | $454M | 8.0% | 2026-Q2 |
| Avoro Capital Advisors LLC | 5,777,777 | $349M | 6.1% | 2026-Q2 |
| Polar Capital Holdings Plc added | 4,570,556 | $276M | 4.9% | 2026-Q2 |
| Driehaus Capital Management LLC trimmed | 4,418,557 | $267M | 4.7% | 2026-Q2 |
| Jupiter Topco LLC new | 4,186,519 | $253M | 4.4% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 3,248,219 | $196M | 3.4% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 2,617,360 | $157M | 2.8% | 2026-Q2 |
| Capital International Investors trimmed | 2,361,639 | $143M | 2.5% | 2026-Q2 |
| STATE STREET CORP added | 1,969,629 | $119M | 2.1% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP added | 1,642,848 | $99M | 1.7% | 2026-Q2 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,615,696 | $98M | 1.7% | 2026-Q2 |
| Affinity Asset Advisors, LLC trimmed | 1,595,000 | $96M | 1.7% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. added | 1,562,276 | $91M | 1.6% | 2026-Q2 |
| WESTFIELD CAPITAL MANAGEMENT CO LP added | 1,507,294 | $91M | 1.6% | 2026-Q2 |
| FRANKLIN RESOURCES INC added | 1,437,712 | $87M | 1.5% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 1,425,492 | $86M | 1.5% | 2026-Q2 |
| CITADEL ADVISORS LLC trimmed | 1,401,242 | $85M | 1.5% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,370,114 | $83M | 1.5% | 2026-Q2 |
| Siren, L.L.C. | 1,318,564 | $80M | 1.4% | 2026-Q2 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. trimmed | 1,290,731 | $78M | 1.4% | 2026-Q2 |
| Pictet Asset Management Holding SA added | 1,187,723 | $72M | 1.3% | 2026-Q2 |
| BRAIDWELL LP trimmed | 1,131,452 | $68M | 1.2% | 2026-Q2 |
| Nuveen, LLC added | 993,126 | $60M | 1.1% | 2026-Q2 |
| Invesco Ltd. added | 903,458 | $55M | 1.0% | 2026-Q2 |
| ORBIMED ADVISORS LLC trimmed | 892,471 | $54M | 0.9% | 2026-Q2 |
| Caligan Partners LP trimmed | 889,944 | $54M | 0.9% | 2026-Q2 |
| AMERICAN CENTURY COMPANIES INC added | 884,319 | $53M | 0.9% | 2026-Q2 |
| FEDERATED HERMES, INC. trimmed | 883,737 | $53M | 0.9% | 2026-Q2 |
| Capital World Investors added | 862,775 | $52M | 0.9% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 773,625 | $47M | 0.8% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 749,651 | $45M | 0.8% | 2026-Q2 |
| Vestal Point Capital, LP added | 700,000 | $42M | 0.7% | 2026-Q2 |
| Alyeska Investment Group, L.P. trimmed | 697,692 | $42M | 0.7% | 2026-Q2 |
| MARSHALL WACE, LLP added | 689,342 | $42M | 0.7% | 2026-Q2 |
| Rock Springs Capital Management LP trimmed | 683,907 | $41M | 0.7% | 2026-Q2 |
| NORTHERN TRUST CORP added | 671,566 | $41M | 0.7% | 2026-Q2 |
| PANAGORA ASSET MANAGEMENT INC new | 664,031 | $40M | 0.7% | 2026-Q2 |
| First Turn Management, LLC trimmed | 600,200 | $36M | 0.6% | 2026-Q2 |
| TUDOR INVESTMENT CORP ET AL added | 545,387 | $33M | 0.6% | 2026-Q2 |
| LOOMIS SAYLES & CO L P trimmed | 527,273 | $32M | 0.6% | 2026-Q2 |
| Octagon Capital Advisors LP | 490,000 | $30M | 0.5% | 2026-Q2 |
| NOVO HOLDINGS A/S | 485,438 | $29M | 0.5% | 2026-Q2 |
| Candriam S.C.A. trimmed | 462,768 | $28M | 0.5% | 2026-Q2 |
| TimesSquare Capital Management, LLC added | 451,593 | $27M | 0.5% | 2026-Q2 |
| Logos Global Management LP | 450,000 | $27M | 0.5% | 2026-Q2 |
| Trails Edge Capital Partners, LP | 440,000 | $27M | 0.5% | 2026-Q2 |
| Bank of New York Mellon Corp added | 421,518 | $25M | 0.4% | 2026-Q2 |
| ALGERT GLOBAL LLC added | 419,773 | $25M | 0.4% | 2026-Q2 |
| Aberdeen Group plc trimmed | 408,736 | $25M | 0.4% | 2026-Q2 |
| MORGAN STANLEY trimmed | 406,257 | $25M | 0.4% | 2026-Q2 |
| Fiera Capital Corp trimmed | 405,638 | $24M | 0.4% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 404,067 | $24M | 0.4% | 2026-Q2 |
| Parkman Healthcare Partners LLC trimmed | 397,379 | $24M | 0.4% | 2026-Q2 |
| Nicholas Investment Partners, LP added | 395,844 | $24M | 0.4% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC added | 376,777 | $23M | 0.4% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 374,748 | $23M | 0.4% | 2026-Q2 |
| BAKER BROS. ADVISORS LP | 370,208 | $22M | 0.4% | 2026-Q2 |
| Jones Hill Capital LP new | 367,900 | $22M | 0.4% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC added | 318,548 | $19M | 0.3% | 2026-Q2 |
| Man Group plc added | 310,617 | $19M | 0.3% | 2026-Q2 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 300,000 | $18M | 0.3% | 2026-Q2 |
| Soleus Capital Management, L.P. trimmed | 267,000 | $16M | 0.3% | 2026-Q2 |
| Jump Financial, LLC added | 260,730 | $16M | 0.3% | 2026-Q2 |
| DAFNA Capital Management LLC | 250,772 | $15M | 0.3% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 249,473 | $15M | 0.3% | 2026-Q2 |
| STATE OF WISCONSIN INVESTMENT BOARD trimmed | 248,821 | $15M | 0.3% | 2026-Q2 |
| NAN FUNG TRINITY (HK) LTD | 247,765 | $15M | 0.3% | 2026-Q2 |
| Duquesne Family Office LLC | 238,600 | $14M | 0.3% | 2026-Q2 |
| Allspring Global Investments Holdings, LLC trimmed | 234,412 | $14M | 0.2% | 2026-Q2 |
| Redmile Group, LLC trimmed | 229,374 | $14M | 0.2% | 2026-Q2 |
| Schonfeld Strategic Advisors LLC trimmed | 227,330 | $14M | 0.2% | 2026-Q2 |
| D. E. Shaw & Co., Inc. added | 223,922 | $14M | 0.2% | 2026-Q2 |
| Patient Square Capital LP trimmed | 220,000 | $13M | 0.2% | 2026-Q2 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 210,471 | $13M | 0.2% | 2026-Q2 |
| JENNISON ASSOCIATES LLC trimmed | 208,060 | $13M | 0.2% | 2026-Q2 |
| NEUBERGER BERMAN GROUP LLC added | 206,604 | $12M | 0.2% | 2026-Q2 |
| Trexquant Investment LP added | 202,455 | $12M | 0.2% | 2026-Q2 |
| DNB Asset Management AS added | 200,451 | $12M | 0.2% | 2026-Q2 |
| Integral Health Asset Management, LLC | 200,000 | $12M | 0.2% | 2026-Q2 |
| Eversept Partners, LP added | 196,532 | $12M | 0.2% | 2026-Q2 |
| BALYASNY ASSET MANAGEMENT L.P. trimmed | 193,407 | $12M | 0.2% | 2026-Q2 |
| DEUTSCHE BANK AG\ added | 191,126 | $12M | 0.2% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 187,110 | $11M | 0.2% | 2026-Q2 |
| SILVERARC CAPITAL MANAGEMENT, LLC trimmed | 186,821 | $11M | 0.2% | 2026-Q2 |
| BOOTHBAY FUND MANAGEMENT, LLC trimmed | 183,343 | $11M | 0.2% | 2026-Q2 |
| NEXTBio Capital Management LP | 183,225 | $11M | 0.2% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 173,945 | $10M | 0.2% | 2026-Q2 |
| ADAR1 Capital Management, LLC trimmed | 166,550 | $10M | 0.2% | 2026-Q2 |
| PEREGRINE CAPITAL MANAGEMENT LLC added | 164,894 | $10M | 0.2% | 2026-Q2 |
| Swiss National Bank added | 162,700 | $10M | 0.2% | 2026-Q2 |
| Foresite Capital Management IV, LLC | 160,000 | $10M | 0.2% | 2026-Q2 |
| Woodline Partners LP added | 155,302 | $9M | 0.2% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 153,227 | $9M | 0.2% | 2026-Q2 |
| HSBC HOLDINGS PLC added | 151,474 | $9M | 0.2% | 2026-Q2 |
| Susquehanna Portfolio Strategies, LLC added | 133,059 | $8M | 0.1% | 2026-Q2 |
| Point72 Asset Management, L.P. added | 130,378 | $8M | 0.1% | 2026-Q2 |
| Granahan Investment Management, LLC added | 129,443 | $8M | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 123,398 | $7M | 0.1% | 2026-Q2 |
| SCHRODER INVESTMENT MANAGEMENT GROUP added | 121,819 | $7M | 0.1% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.