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Institutional Ownership · SEC Form 13F

Who owns XENE (XENE)


Which tracked institutional funds hold XENE, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See XENE company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

292
Institutional holders
98,270,337
Shares held (tracked funds)

How the tape is positioned

The tracked-fund tape on XENE is one-sided between 2025-Q4 and 2026-Q1: 165 added or opened and 39 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

XENE’s largest tracked holder by dollar value, FMR LLC, sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 0.1pp gap the other way — the median holder sizes XENE more heavily than its largest holder by dollar value does.

Book-share is each fund’s reported value in XENE divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 292 tracked filers holding XENE, 206 increased or opened the position and 98 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in XENE between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 46

  • Alyeska Investment Group, L.P.$76M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$32M
  • Octagon Capital Advisors LP$28M
  • NOVO HOLDINGS A/S$28M
  • Logos Global Management LP$26M
  • Schonfeld Strategic Advisors LLC$19M

Full exits 18

  • VANGUARD GROUP INC$30M
  • DIMENSIONAL FUND ADVISORS LP$20M
  • Deep Track Capital, LP$16M
  • TWO SIGMA ADVISERS, LP$12M
  • Iron Triangle Partners LP$10M
  • PERCEPTIVE ADVISORS LLC$9M

Largest adds

  • FMR LLC$229M
  • Polar Capital Holdings Plc$146M
  • CITADEL ADVISORS LLC$95M
  • Avoro Capital Advisors LLC$93M
  • DEERFIELD MANAGEMENT COMPANY, L.P.$70M
  • WELLINGTON MANAGEMENT GROUP LLP$66M

Largest trims

  • Commodore Capital LP$33M
  • BlackRock, Inc.$22M
  • MILLENNIUM MANAGEMENT LLC$17M
  • BARCLAYS PLC$13M
  • ALLIANCEBERNSTEIN L.P.$9M
  • STEMPOINT CAPITAL LP$7M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
FMR LLC added10,818,491$629M11.3%2026-Q1
Avoro Capital Advisors LLC added5,777,777$336M6.0%2026-Q1
WELLINGTON MANAGEMENT GROUP LLP added4,808,134$280M5.0%2026-Q1
Driehaus Capital Management LLC trimmed4,491,653$261M4.7%2026-Q1
Polar Capital Holdings Plc added4,405,312$256M4.6%2026-Q1
JANUS HENDERSON GROUP PLC added4,175,982$243M4.4%2026-Q1
BlackRock, Inc. trimmed3,558,714$207M3.7%2026-Q1
Capital International Investors trimmed2,674,727$156M2.8%2026-Q1
CITADEL ADVISORS LLC added2,652,990$154M2.8%2026-Q1
JPMORGAN CHASE & CO added1,923,610$107M1.9%2026-Q1
STATE STREET CORP added1,720,533$100M1.8%2026-Q1
Affinity Asset Advisors, LLC added1,675,000$97M1.8%2026-Q1
DEERFIELD MANAGEMENT COMPANY, L.P. added1,615,696$94M1.7%2026-Q1
Holocene Advisors, LP added1,518,686$88M1.6%2026-Q1
WESTFIELD CAPITAL MANAGEMENT CO LP added1,401,483$81M1.5%2026-Q1
Caligan Partners LP added1,393,027$81M1.5%2026-Q1
BNP PARIBAS ASSET MANAGEMENT Holding S.A. added1,342,028$78M1.4%2026-Q1
BRAIDWELL LP trimmed1,338,452$78M1.4%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ added1,329,591$77M1.4%2026-Q1
JENNISON ASSOCIATES LLC added1,318,814$77M1.4%2026-Q1
Siren, L.L.C. added1,318,564$77M1.4%2026-Q1
Alyeska Investment Group, L.P. added1,299,469$76M1.4%2026-Q1
FRANKLIN RESOURCES INC added1,280,577$74M1.3%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added1,092,932$64M1.1%2026-Q1
ALLIANCEBERNSTEIN L.P. trimmed1,403,297$63M1.1%2026-Q1
ORBIMED ADVISORS LLC added1,059,971$62M1.1%2026-Q1
FEDERATED HERMES, INC. added972,237$57M1.0%2026-Q1
T. Rowe Price Investment Management, Inc. added951,955$55M1.0%2026-Q1
Capital World Investors added840,072$49M0.9%2026-Q1
Commodore Capital LP trimmed825,000$48M0.9%2026-Q1
First Turn Management, LLC trimmed786,844$46M0.8%2026-Q1
GOLDMAN SACHS GROUP INC added769,875$45M0.8%2026-Q1
Rock Springs Capital Management LP trimmed763,020$44M0.8%2026-Q1
Fiera Capital Corp added709,529$41M0.7%2026-Q1
AMERICAN CENTURY COMPANIES INC trimmed679,314$40M0.7%2026-Q1
Pictet Asset Management Holding SA added679,709$39M0.7%2026-Q1
Vestal Point Capital, LP added639,900$37M0.7%2026-Q1
Aberdeen Group plc trimmed609,929$35M0.6%2026-Q1
TWO SIGMA INVESTMENTS, LP added606,085$35M0.6%2026-Q1
MPM BIOIMPACT LLC added588,706$34M0.6%2026-Q1
LOOMIS SAYLES & CO L P trimmed564,897$33M0.6%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new543,062$32M0.6%2026-Q1
NORTHERN TRUST CORP added527,783$31M0.6%2026-Q1
Parkman Healthcare Partners LLC added497,035$29M0.5%2026-Q1
TUDOR INVESTMENT CORP ET AL added495,591$29M0.5%2026-Q1
Octagon Capital Advisors LP new490,000$28M0.5%2026-Q1
NOVO HOLDINGS A/S new485,438$28M0.5%2026-Q1
Candriam S.C.A. added476,494$28M0.5%2026-Q1
MORGAN STANLEY added473,759$28M0.5%2026-Q1
ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed470,000$27M0.5%2026-Q1
Logos Global Management LP trimmed450,000$26M0.5%2026-Q1
Trails Edge Capital Partners, LP trimmed440,000$26M0.5%2026-Q1
Bank of New York Mellon Corp added396,138$23M0.4%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added375,166$22M0.4%2026-Q1
BAKER BROS. ADVISORS LP370,208$22M0.4%2026-Q1
TimesSquare Capital Management, LLC trimmed359,293$21M0.4%2026-Q1
Schonfeld Strategic Advisors LLC added324,722$19M0.3%2026-Q1
Sofinnova Investments, Inc. added305,216$18M0.3%2026-Q1
RENAISSANCE TECHNOLOGIES LLC added300,500$17M0.3%2026-Q1
Soleus Capital Management, L.P. added292,000$17M0.3%2026-Q1
BOOTHBAY FUND MANAGEMENT, LLC added270,412$16M0.3%2026-Q1
BANK OF AMERICA CORP /DE/ added265,267$15M0.3%2026-Q1
ALGERT GLOBAL LLC added264,200$15M0.3%2026-Q1
Redmile Group, LLC added262,674$15M0.3%2026-Q1
STATE OF WISCONSIN INVESTMENT BOARD added254,483$15M0.3%2026-Q1
DAFNA Capital Management LLC trimmed250,772$15M0.3%2026-Q1
Nuveen, LLC added250,036$15M0.3%2026-Q1
NAN FUNG TRINITY (HK) LTD added247,765$14M0.3%2026-Q1
Nicholas Investment Partners, LP added247,101$14M0.3%2026-Q1
Allspring Global Investments Holdings, LLC new246,306$14M0.3%2026-Q1
Duquesne Family Office LLC new238,600$14M0.2%2026-Q1
BARCLAYS PLC trimmed238,209$14M0.2%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. added233,905$14M0.2%2026-Q1
ADAR1 Capital Management, LLC added228,899$13M0.2%2026-Q1
Patient Square Capital LP added227,000$13M0.2%2026-Q1
MILLENNIUM MANAGEMENT LLC trimmed201,785$12M0.2%2026-Q1
Integral Health Asset Management, LLC new200,000$12M0.2%2026-Q1
SILVERARC CAPITAL MANAGEMENT, LLC added197,759$11M0.2%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added189,080$11M0.2%2026-Q1
NEW YORK STATE COMMON RETIREMENT FUND added188,505$11M0.2%2026-Q1
NEXTBio Capital Management LP trimmed183,225$11M0.2%2026-Q1
DNB Asset Management AS trimmed181,085$11M0.2%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP added177,137$10M0.2%2026-Q1
ExodusPoint Capital Management, LP added173,425$10M0.2%2026-Q1
DEUTSCHE BANK AG\ trimmed162,682$9M0.2%2026-Q1
Foresite Capital Management IV, LLC160,000$9M0.2%2026-Q1
Swiss National Bank added157,700$9M0.2%2026-Q1
Jump Financial, LLC added155,776$9M0.2%2026-Q1
Woodline Partners LP added150,302$9M0.2%2026-Q1
PEREGRINE CAPITAL MANAGEMENT LLC trimmed143,136$8M0.1%2026-Q1
SAMLYN CAPITAL, LLC trimmed1,016,381$34M0.6%2025-Q1 stale
VANGUARD GROUP INC trimmed664,641$30M0.5%2025-Q4 stale
DIMENSIONAL FUND ADVISORS LP trimmed452,147$20M0.4%2025-Q4 stale
Saturn V Capital Management LP added503,701$20M0.4%2025-Q3 stale
Boxer Capital Management, LLC600,000$20M0.4%2025-Q1 stale
Deep Track Capital, LP trimmed366,435$16M0.3%2025-Q4 stale
Tri Locum Partners LP added366,102$15M0.3%2025-Q3 stale
TWO SIGMA ADVISERS, LP added259,320$12M0.2%2025-Q4 stale
Iron Triangle Partners LP new233,688$10M0.2%2025-Q4 stale
PERCEPTIVE ADVISORS LLC200,791$9M0.2%2025-Q4 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership