Who owns Wave Life Sciences Ltd. (WVE)
Which tracked institutional funds hold WVE, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See WVE company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on WVE is one-sided between 2025-Q4 and 2026-Q1: 34 added or opened and 126 trimmed or exited — on balance reducing.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
WVE’s largest tracked holder by dollar value, RA CAPITAL MANAGEMENT, L.P., sizes it at 2.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 2.0pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in WVE divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 233 tracked filers holding WVE, 156 increased or opened the position and 86 reduced or closed it; over the same quarter, open-market insider Form 4s were net purchases.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in WVE between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 21
- MARSHALL WACE, LLP$13M
- VANGUARD CAPITAL MANAGEMENT LLC$12M
- VANGUARD PORTFOLIO MANAGEMENT LLC$9M
- VANGUARD FIDUCIARY TRUST CO$6M
- SymBiosis Capital Partners, LLC$5M
- Aberdeen Group plc$4M
Full exits 22
- Darwin Global Management, Ltd.$125M
- VANGUARD GROUP INC$44M
- LOOMIS SAYLES & CO L P$35M
- EVENTIDE ASSET MANAGEMENT, LLC$8M
- Exome Asset Management LLC$7M
- BOONE CAPITAL MANAGEMENT LLC$6M
Largest adds
- ALGERT GLOBAL LLC$7M
- Connor, Clark & Lunn Investment Management Ltd.$3M
- MORGAN STANLEY$3M
- CITIGROUP INC$3M
- CITADEL ADVISORS LLC$3M
- Trexquant Investment LP$1M
Largest trims
- FMR LLC$220M
- GSK plc$178M
- ADAGE CAPITAL PARTNERS GP, L.L.C.$159M
- RA CAPITAL MANAGEMENT, L.P.$114M
- BlackRock, Inc.$113M
- MAVERICK CAPITAL LTD$84M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. added | 26,975,505 | $196M | 12.9% | 2026-Q1 |
| GSK plc | 18,245,691 | $132M | 8.7% | 2026-Q1 |
| BlackRock, Inc. added | 14,117,412 | $102M | 6.8% | 2026-Q1 |
| MAVERICK CAPITAL LTD added | 10,161,399 | $74M | 4.9% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 8,704,550 | $63M | 4.2% | 2026-Q1 |
| Driehaus Capital Management LLC trimmed | 5,431,021 | $39M | 2.6% | 2026-Q1 |
| FEDERATED HERMES, INC. added | 5,317,457 | $39M | 2.5% | 2026-Q1 |
| FMR LLC trimmed | 5,189,890 | $38M | 2.5% | 2026-Q1 |
| 683 Capital Management, LLC added | 4,900,000 | $36M | 2.3% | 2026-Q1 |
| PRIMECAP MANAGEMENT CO/CA/ added | 4,832,952 | $35M | 2.3% | 2026-Q1 |
| M28 Capital Management LP trimmed | 4,588,284 | $33M | 2.2% | 2026-Q1 |
| STATE STREET CORP added | 3,674,033 | $27M | 1.8% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 3,579,099 | $26M | 1.7% | 2026-Q1 |
| Siren, L.L.C. | 2,450,000 | $18M | 1.2% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 2,202,856 | $16M | 1.1% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP added | 1,878,115 | $14M | 0.9% | 2026-Q1 |
| First Light Asset Management, LLC trimmed | 1,843,968 | $13M | 0.9% | 2026-Q1 |
| MARSHALL WACE, LLP added | 1,789,882 | $13M | 0.9% | 2026-Q1 |
| Pfizer Inc | 1,875,000 | $12M | 0.8% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 1,611,853 | $12M | 0.8% | 2026-Q1 |
| Squarepoint Ops LLC added | 1,462,390 | $11M | 0.7% | 2026-Q1 |
| Affinity Asset Advisors, LLC trimmed | 1,401,727 | $10M | 0.7% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC trimmed | 1,383,590 | $10M | 0.7% | 2026-Q1 |
| MORGAN STANLEY added | 1,361,001 | $10M | 0.7% | 2026-Q1 |
| RTW INVESTMENTS, LP | 1,350,000 | $10M | 0.6% | 2026-Q1 |
| SCHRODER INVESTMENT MANAGEMENT GROUP added | 1,441,059 | $10M | 0.6% | 2026-Q1 |
| ALGERT GLOBAL LLC added | 1,315,589 | $10M | 0.6% | 2026-Q1 |
| EMERALD ADVISERS, LLC trimmed | 1,261,183 | $9M | 0.6% | 2026-Q1 |
| NORTHERN TRUST CORP added | 1,189,230 | $9M | 0.6% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed | 1,179,279 | $9M | 0.6% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 1,176,207 | $9M | 0.6% | 2026-Q1 |
| Pictet Asset Management Holding SA added | 1,149,127 | $8M | 0.5% | 2026-Q1 |
| Trexquant Investment LP added | 1,089,642 | $8M | 0.5% | 2026-Q1 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 1,000,000 | $7M | 0.5% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 972,241 | $7M | 0.5% | 2026-Q1 |
| Kynam Capital Management, LP trimmed | 965,193 | $7M | 0.5% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 878,833 | $6M | 0.4% | 2026-Q1 |
| BAKER BROS. ADVISORS LP added | 822,638 | $6M | 0.4% | 2026-Q1 |
| EMERALD MUTUAL FUND ADVISERS TRUST trimmed | 814,529 | $6M | 0.4% | 2026-Q1 |
| SymBiosis Capital Partners, LLC new | 750,000 | $5M | 0.4% | 2026-Q1 |
| Nuveen, LLC added | 657,720 | $5M | 0.3% | 2026-Q1 |
| Connor, Clark & Lunn Investment Management Ltd. added | 624,735 | $5M | 0.3% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 670,170 | $4M | 0.3% | 2026-Q1 |
| TANG CAPITAL MANAGEMENT LLC | 600,000 | $4M | 0.3% | 2026-Q1 |
| RENAISSANCE TECHNOLOGIES LLC added | 597,220 | $4M | 0.3% | 2026-Q1 |
| Aberdeen Group plc new | 550,000 | $4M | 0.3% | 2026-Q1 |
| SPHERA FUNDS MANAGEMENT LTD. added | 548,272 | $4M | 0.3% | 2026-Q1 |
| UBS Group AG added | 538,997 | $4M | 0.3% | 2026-Q1 |
| KENNEDY CAPITAL MANAGEMENT LLC added | 519,768 | $4M | 0.2% | 2026-Q1 |
| CITIGROUP INC added | 501,477 | $4M | 0.2% | 2026-Q1 |
| Walleye Capital LLC added | 493,512 | $4M | 0.2% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC added | 447,416 | $3M | 0.2% | 2026-Q1 |
| Universal- Beteiligungs- und Servicegesellschaft mbH added | 415,458 | $3M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp added | 361,204 | $3M | 0.2% | 2026-Q1 |
| Jump Financial, LLC added | 360,054 | $3M | 0.2% | 2026-Q1 |
| Woodline Partners LP | 350,531 | $3M | 0.2% | 2026-Q1 |
| TD Asset Management Inc added | 338,826 | $2M | 0.2% | 2026-Q1 |
| Aquatic Capital Management LLC added | 323,573 | $2M | 0.2% | 2026-Q1 |
| HRT FINANCIAL LP added | 321,376 | $2M | 0.2% | 2026-Q1 |
| Newtyn Management, LLC | 300,000 | $2M | 0.1% | 2026-Q1 |
| ALLIANCEBERNSTEIN L.P. added | 125,096 | $2M | 0.1% | 2026-Q1 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 288,502 | $2M | 0.1% | 2026-Q1 |
| GSA CAPITAL PARTNERS LLP added | 282,719 | $2M | 0.1% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 281,023 | $2M | 0.1% | 2026-Q1 |
| PLATINUM INVESTMENT MANAGEMENT LTD added | 275,269 | $2M | 0.1% | 2026-Q1 |
| Moody Aldrich Partners LLC trimmed | 272,533 | $2M | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 259,825 | $2M | 0.1% | 2026-Q1 |
| Itau Unibanco Holding S.A. | 102,000 | $2M | 0.1% | 2026-Q1 |
| Privium Fund Management B.V. added | 241,010 | $2M | 0.1% | 2026-Q1 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE added | 240,983 | $2M | 0.1% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 236,760 | $2M | 0.1% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 229,608 | $2M | 0.1% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 225,114 | $2M | 0.1% | 2026-Q1 |
| Swiss National Bank | 219,700 | $2M | 0.1% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. added | 211,074 | $2M | 0.1% | 2026-Q1 |
| Darwin Global Management, Ltd. new | 7,298,421 | $125M | 8.3% | 2025-Q4 stale |
| VANGUARD GROUP INC trimmed | 2,568,500 | $44M | 2.9% | 2025-Q4 stale |
| LOOMIS SAYLES & CO L P trimmed | 2,040,223 | $35M | 2.3% | 2025-Q4 stale |
| STEMPOINT CAPITAL LP added | 2,110,152 | $15M | 1.0% | 2025-Q3 stale |
| MPM BIOIMPACT LLC | 1,505,262 | $11M | 0.7% | 2025-Q3 stale |
| Artisan Partners Limited Partnership trimmed | 1,232,926 | $9M | 0.6% | 2025-Q3 stale |
| EVENTIDE ASSET MANAGEMENT, LLC added | 500,000 | $8M | 0.6% | 2025-Q4 stale |
| SILVERARC CAPITAL MANAGEMENT, LLC added | 1,050,374 | $8M | 0.6% | 2025-Q1 stale |
| Polar Capital Holdings Plc added | 1,062,276 | $8M | 0.5% | 2025-Q3 stale |
| Exome Asset Management LLC trimmed | 421,488 | $7M | 0.5% | 2025-Q4 stale |
| BOONE CAPITAL MANAGEMENT LLC new | 352,144 | $6M | 0.4% | 2025-Q4 stale |
| JACOBS LEVY EQUITY MANAGEMENT, INC added | 338,546 | $6M | 0.4% | 2025-Q4 stale |
| Jain Global LLC new | 328,145 | $6M | 0.4% | 2025-Q4 stale |
| Informed Momentum Co LLC added | 248,815 | $4M | 0.3% | 2025-Q4 stale |
| Squadron Capital Management LLC new | 175,000 | $3M | 0.2% | 2025-Q4 stale |
| PRINCIPAL FINANCIAL GROUP INC trimmed | 170,170 | $3M | 0.2% | 2025-Q4 stale |
| Ensign Peak Advisors, Inc | 313,307 | $2M | 0.2% | 2025-Q3 stale |
| Avidity Partners Management LP trimmed | 297,500 | $2M | 0.1% | 2025-Q3 stale |
| JANE STREET GROUP, LLC trimmed | 110,924 | $2M | 0.1% | 2025-Q4 stale |
| TWO SIGMA ADVISERS, LP added | 251,700 | $2M | 0.1% | 2025-Q3 stale |
| LMR Partners LLP added | 100,000 | $2M | 0.1% | 2025-Q4 stale |
| SEVEN GRAND MANAGERS, LLC new | 100,000 | $2M | 0.1% | 2025-Q4 stale |
| DARK FOREST CAPITAL MANAGEMENT LP trimmed | 95,068 | $2M | 0.1% | 2025-Q4 stale |
| PRELUDE CAPITAL MANAGEMENT, LLC trimmed | 93,202 | $2M | 0.1% | 2025-Q4 stale |
| Prescott Group Capital Management, L.L.C. new | 90,000 | $2M | 0.1% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.