Who owns Wave Life Sciences (WVE)
Which tracked institutional funds hold WVE, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See WVE company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
39 tracked funds added or opened WVE while 73 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
WVE’s largest tracked holder by dollar value, RA CAPITAL MANAGEMENT, L.P., sizes it at 1.4% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 1.3pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in WVE divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 231 tracked filers holding WVE, 145 increased or opened the position and 104 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in WVE between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 8
- READYSTATE ASSET MANAGEMENT LP$27M
- DIMENSIONAL FUND ADVISORS LP$10M
- HSBC HOLDINGS PLC$2M
- Ishara Investments LP$2M
- ExodusPoint Capital Management, LP$1M
- ALPS ADVISORS INC$1M
Full exits 20
- Siren, L.L.C.$18M
- First Light Asset Management, LLC$13M
- Affinity Asset Advisors, LLC$10M
- ADAGE CAPITAL PARTNERS GP, L.L.C.$7M
- Kynam Capital Management, LP$7M
- SymBiosis Capital Partners, LLC$5M
Largest adds
- Qube Research & Technologies Ltd$15M
- D. E. Shaw & Co., Inc.$10M
- BlackRock, Inc.$9M
- Point72 Asset Management, L.P.$8M
- TWO SIGMA INVESTMENTS, LP$8M
- ALGERT GLOBAL LLC$7M
Largest trims
- PRICE T ROWE ASSOCIATES INC /MD/$53M
- RA CAPITAL MANAGEMENT, L.P.$39M
- FEDERATED HERMES, INC.$30M
- GSK plc$26M
- MAVERICK CAPITAL LTD$14M
- CITADEL ADVISORS LLC$13M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 26,975,505 | $157M | 11.2% | 2026-Q2 |
| BlackRock, Inc. added | 19,202,461 | $112M | 8.0% | 2026-Q2 |
| GSK plc | 18,245,691 | $106M | 7.6% | 2026-Q2 |
| MAVERICK CAPITAL LTD added | 10,278,115 | $60M | 4.3% | 2026-Q2 |
| Driehaus Capital Management LLC added | 5,443,143 | $32M | 2.3% | 2026-Q2 |
| PRIMECAP MANAGEMENT CO/CA/ added | 5,354,622 | $31M | 2.2% | 2026-Q2 |
| 683 Capital Management, LLC added | 4,950,000 | $29M | 2.1% | 2026-Q2 |
| FMR LLC trimmed | 4,922,477 | $29M | 2.0% | 2026-Q2 |
| STATE STREET CORP added | 4,839,317 | $28M | 2.0% | 2026-Q2 |
| READYSTATE ASSET MANAGEMENT LP new | 4,727,139 | $27M | 2.0% | 2026-Q2 |
| M28 Capital Management LP | 4,588,284 | $27M | 1.9% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 3,869,998 | $22M | 1.6% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP added | 3,707,686 | $22M | 1.5% | 2026-Q2 |
| ALGERT GLOBAL LLC added | 2,817,615 | $16M | 1.2% | 2026-Q2 |
| Qube Research & Technologies Ltd added | 2,776,000 | $16M | 1.2% | 2026-Q2 |
| Squarepoint Ops LLC added | 2,541,442 | $15M | 1.1% | 2026-Q2 |
| MORGAN STANLEY added | 2,422,705 | $14M | 1.0% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 2,110,751 | $12M | 0.9% | 2026-Q2 |
| Pfizer Inc | 1,875,000 | $11M | 0.8% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC added | 1,811,282 | $11M | 0.8% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ trimmed | 1,806,467 | $10M | 0.8% | 2026-Q2 |
| D. E. Shaw & Co., Inc. added | 1,772,228 | $10M | 0.7% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 1,751,403 | $10M | 0.7% | 2026-Q2 |
| SCHRODER INVESTMENT MANAGEMENT GROUP added | 1,746,643 | $10M | 0.7% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP new | 1,707,809 | $10M | 0.7% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC added | 1,704,520 | $10M | 0.7% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC added | 1,648,045 | $10M | 0.7% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 1,622,342 | $9M | 0.7% | 2026-Q2 |
| Point72 Asset Management, L.P. added | 1,484,989 | $9M | 0.6% | 2026-Q2 |
| FEDERATED HERMES, INC. trimmed | 1,466,234 | $9M | 0.6% | 2026-Q2 |
| RTW INVESTMENTS, LP | 1,350,000 | $8M | 0.6% | 2026-Q2 |
| NORTHERN TRUST CORP added | 1,253,500 | $7M | 0.5% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 1,224,445 | $7M | 0.5% | 2026-Q2 |
| EMERALD ADVISERS, LLC trimmed | 1,223,965 | $7M | 0.5% | 2026-Q2 |
| MARSHALL WACE, LLP trimmed | 999,533 | $6M | 0.4% | 2026-Q2 |
| Pictet Asset Management Holding SA trimmed | 917,409 | $5M | 0.4% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 887,677 | $5M | 0.4% | 2026-Q2 |
| Aberdeen Group plc added | 876,458 | $5M | 0.4% | 2026-Q2 |
| EMERALD MUTUAL FUND ADVISERS TRUST added | 847,999 | $5M | 0.4% | 2026-Q2 |
| BAKER BROS. ADVISORS LP | 822,638 | $5M | 0.3% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS added | 811,057 | $5M | 0.3% | 2026-Q2 |
| CAPITAL FUND MANAGEMENT S.A. added | 734,746 | $4M | 0.3% | 2026-Q2 |
| SPHERA FUNDS MANAGEMENT LTD. added | 638,272 | $4M | 0.3% | 2026-Q2 |
| JPMORGAN CHASE & CO trimmed | 618,172 | $4M | 0.3% | 2026-Q2 |
| Y-Intercept (Hong Kong) Ltd added | 610,094 | $4M | 0.3% | 2026-Q2 |
| Susquehanna Portfolio Strategies, LLC added | 608,194 | $4M | 0.3% | 2026-Q2 |
| TANG CAPITAL MANAGEMENT LLC | 600,000 | $3M | 0.2% | 2026-Q2 |
| Walleye Capital LLC added | 585,453 | $3M | 0.2% | 2026-Q2 |
| Nuveen, LLC trimmed | 549,282 | $3M | 0.2% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 517,054 | $3M | 0.2% | 2026-Q2 |
| Man Group plc added | 505,456 | $3M | 0.2% | 2026-Q2 |
| UBS Group AG trimmed | 505,237 | $3M | 0.2% | 2026-Q2 |
| CITADEL ADVISORS LLC trimmed | 480,154 | $3M | 0.2% | 2026-Q2 |
| Jump Financial, LLC added | 452,502 | $3M | 0.2% | 2026-Q2 |
| XTX Topco Ltd added | 439,933 | $3M | 0.2% | 2026-Q2 |
| KENNEDY CAPITAL MANAGEMENT LLC trimmed | 429,121 | $2M | 0.2% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP added | 423,005 | $2M | 0.2% | 2026-Q2 |
| Bank of New York Mellon Corp added | 416,579 | $2M | 0.2% | 2026-Q2 |
| Universal- Beteiligungs- und Servicegesellschaft mbH trimmed | 408,894 | $2M | 0.2% | 2026-Q2 |
| Connor, Clark & Lunn Investment Management Ltd. trimmed | 406,478 | $2M | 0.2% | 2026-Q2 |
| Trexquant Investment LP trimmed | 380,169 | $2M | 0.2% | 2026-Q2 |
| HSBC HOLDINGS PLC added | 370,449 | $2M | 0.2% | 2026-Q2 |
| Woodline Partners LP | 350,531 | $2M | 0.1% | 2026-Q2 |
| Ishara Investments LP new | 328,000 | $2M | 0.1% | 2026-Q2 |
| BARCLAYS PLC added | 309,580 | $2M | 0.1% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 299,400 | $2M | 0.1% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 276,818 | $2M | 0.1% | 2026-Q2 |
| PLATINUM INVESTMENT MANAGEMENT LTD | 275,269 | $2M | 0.1% | 2026-Q2 |
| Darwin Global Management, Ltd. new | 7,298,421 | $125M | 9.0% | 2025-Q4 stale (2 quarters behind) |
| VANGUARD GROUP INC added | 3,573,746 | $61M | 4.4% | 2025-Q4 stale (2 quarters behind) |
| LOOMIS SAYLES & CO L P trimmed | 2,040,223 | $35M | 2.5% | 2025-Q4 stale (2 quarters behind) |
| Siren, L.L.C. | 2,450,000 | $18M | 1.3% | 2026-Q1 stale (1 quarter behind) |
| STEMPOINT CAPITAL LP added | 2,110,152 | $15M | 1.1% | 2025-Q3 stale (3 quarters behind) |
| First Light Asset Management, LLC trimmed | 1,843,968 | $13M | 1.0% | 2026-Q1 stale (1 quarter behind) |
| MPM BIOIMPACT LLC | 1,505,262 | $11M | 0.8% | 2025-Q3 stale (3 quarters behind) |
| Affinity Asset Advisors, LLC trimmed | 1,401,727 | $10M | 0.7% | 2026-Q1 stale (1 quarter behind) |
| Artisan Partners Limited Partnership trimmed | 1,232,926 | $9M | 0.6% | 2025-Q3 stale (3 quarters behind) |
| EVENTIDE ASSET MANAGEMENT, LLC new | 500,000 | $8M | 0.6% | 2025-Q4 stale (2 quarters behind) |
| Polar Capital Holdings Plc added | 1,062,276 | $8M | 0.6% | 2025-Q3 stale (3 quarters behind) |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 1,000,000 | $7M | 0.5% | 2026-Q1 stale (1 quarter behind) |
| Exome Asset Management LLC new | 421,488 | $7M | 0.5% | 2025-Q4 stale (2 quarters behind) |
| Kynam Capital Management, LP trimmed | 965,193 | $7M | 0.5% | 2026-Q1 stale (1 quarter behind) |
| BOONE CAPITAL MANAGEMENT LLC new | 352,144 | $6M | 0.4% | 2025-Q4 stale (2 quarters behind) |
| JACOBS LEVY EQUITY MANAGEMENT, INC added | 338,546 | $6M | 0.4% | 2025-Q4 stale (2 quarters behind) |
| SymBiosis Capital Partners, LLC new | 750,000 | $5M | 0.4% | 2026-Q1 stale (1 quarter behind) |
| Informed Momentum Co LLC added | 248,815 | $4M | 0.3% | 2025-Q4 stale (2 quarters behind) |
| Squadron Capital Management LLC new | 175,000 | $3M | 0.2% | 2025-Q4 stale (2 quarters behind) |
| PRINCIPAL FINANCIAL GROUP INC trimmed | 170,170 | $3M | 0.2% | 2025-Q4 stale (2 quarters behind) |
| Aquatic Capital Management LLC added | 323,573 | $2M | 0.2% | 2026-Q1 stale (1 quarter behind) |
| Ensign Peak Advisors, Inc | 313,307 | $2M | 0.2% | 2025-Q3 stale (3 quarters behind) |
| Avidity Partners Management LP new | 297,500 | $2M | 0.2% | 2025-Q3 stale (3 quarters behind) |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 288,502 | $2M | 0.1% | 2026-Q1 stale (1 quarter behind) |
| GSA CAPITAL PARTNERS LLP added | 282,719 | $2M | 0.1% | 2026-Q1 stale (1 quarter behind) |
| Moody Aldrich Partners LLC trimmed | 272,533 | $2M | 0.1% | 2026-Q1 stale (1 quarter behind) |
| JANE STREET GROUP, LLC trimmed | 110,924 | $2M | 0.1% | 2025-Q4 stale (2 quarters behind) |
| TWO SIGMA ADVISERS, LP added | 251,700 | $2M | 0.1% | 2025-Q3 stale (3 quarters behind) |
| Itau Unibanco Holding S.A. | 102,000 | $2M | 0.1% | 2026-Q1 stale (1 quarter behind) |
| LMR Partners LLP new | 100,000 | $2M | 0.1% | 2025-Q4 stale (2 quarters behind) |
| SEVEN GRAND MANAGERS, LLC new | 100,000 | $2M | 0.1% | 2025-Q4 stale (2 quarters behind) |
| DARK FOREST CAPITAL MANAGEMENT LP trimmed | 95,068 | $2M | 0.1% | 2025-Q4 stale (2 quarters behind) |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.