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Institutional Ownership · SEC Form 13F

Who owns Vertex Pharmaceuticals (VRTX)


Which tracked institutional funds hold VRTX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See VRTX company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

1,682
Institutional holders
237M
Shares held (tracked funds)
93.5%
Of shares outstanding

How the tape is positioned

The tracked-fund tape on VRTX is one-sided between 2026-Q1 and 2026-Q2: 19 added or opened and 1015 trimmed or exited — on balance reducing.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

VRTX’s largest tracked holder by dollar value, Capital World Investors, sizes it at 1.8% of its own reported 13F book, while the median holder sizes it at 0.2% of theirs — a 1.6pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in VRTX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 1682 tracked filers holding VRTX, 826 increased or opened the position and 734 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in VRTX between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 2

  • TUDOR INVESTMENT CORP ET AL$15M
  • Schonfeld Strategic Advisors LLC$1M

Full exits 1007

  • VANGUARD CAPITAL MANAGEMENT LLC$7.4B
  • JPMORGAN CHASE & CO$3.1B
  • GEODE CAPITAL MANAGEMENT, LLC$2.7B
  • VANGUARD PORTFOLIO MANAGEMENT LLC$2.3B
  • LOOMIS SAYLES & CO L P$1.8B
  • ALLIANCEBERNSTEIN L.P.$1.8B

Largest adds

  • Capital World Investors$1.6B
  • BlackRock, Inc.$1.6B
  • Invesco Ltd.$1.6B
  • STATE STREET CORP$659M
  • Capital Research Global Investors$248M
  • AQR CAPITAL MANAGEMENT LLC$230M

Largest trims

  • FMR LLC$170M
  • NORGES BANK$155M
  • D. E. Shaw & Co., Inc.$110M
  • RENAISSANCE TECHNOLOGIES LLC$29M
  • TWO SIGMA INVESTMENTS, LP$27M
  • Point72 Asset Management, L.P.$8M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
Capital World Investors added26,115,014$13.0B11.4%2026-Q2
BlackRock, Inc. added24,109,373$12.0B10.5%2026-Q2
Capital Research Global Investors trimmed19,490,637$9.7B8.5%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC new16,512,810$7.4B6.5%2026-Q1
STATE STREET CORP added11,871,459$5.9B5.2%2026-Q2
Invesco Ltd. added8,043,052$4.0B3.5%2026-Q2
JPMORGAN CHASE & CO added7,033,156$3.1B2.7%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added6,139,621$2.7B2.4%2026-Q1
Capital International Investors trimmed4,695,144$2.3B2.0%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC new5,145,609$2.3B2.0%2026-Q1
LOOMIS SAYLES & CO L P trimmed4,003,821$1.8B1.6%2026-Q1
ALLIANCEBERNSTEIN L.P. trimmed3,910,786$1.8B1.6%2026-Q1
WELLINGTON MANAGEMENT GROUP LLP added3,247,658$1.6B1.4%2026-Q2
NORGES BANK trimmed2,971,681$1.5B1.3%2026-Q2
MORGAN STANLEY added3,188,881$1.4B1.2%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added3,057,396$1.4B1.2%2026-Q1
BANK OF AMERICA CORP /DE/ trimmed2,878,183$1.3B1.1%2026-Q1
JENNISON ASSOCIATES LLC trimmed2,740,059$1.2B1.1%2026-Q1
Clearbridge Investments, LLC trimmed2,700,975$1.2B1.1%2026-Q1
AMERIPRISE FINANCIAL INC added2,633,481$1.2B1.0%2026-Q1
NORTHERN TRUST CORP trimmed2,564,264$1.1B1.0%2026-Q1
GOLDMAN SACHS GROUP INC added2,417,875$1.1B0.9%2026-Q1
JANUS HENDERSON GROUP PLC trimmed2,131,527$952M0.8%2026-Q1
Legal & General Group Plc trimmed1,955,764$873M0.8%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ trimmed1,728,421$859M0.8%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added1,920,871$858M0.8%2026-Q1
VICTORY CAPITAL MANAGEMENT INC trimmed1,888,521$843M0.7%2026-Q1
FMR LLC trimmed1,457,158$724M0.6%2026-Q2
Bank of New York Mellon Corp added1,586,427$708M0.6%2026-Q1
DEUTSCHE BANK AG\ trimmed1,537,736$687M0.6%2026-Q1
Amundi added1,472,496$658M0.6%2026-Q1
VANGUARD FIDUCIARY TRUST CO new1,465,724$655M0.6%2026-Q1
WCM INVESTMENT MANAGEMENT, LLC added1,152,094$576M0.5%2026-Q2
ROYAL BANK OF CANADA trimmed1,111,871$496M0.4%2026-Q1
Nuveen, LLC added1,084,495$484M0.4%2026-Q1
DIMENSIONAL FUND ADVISORS LP added989,342$442M0.4%2026-Q1
EDGEWOOD MANAGEMENT LLC trimmed905,129$404M0.4%2026-Q1
BNP PARIBAS ASSET MANAGEMENT Holding S.A. added848,047$379M0.3%2026-Q1
AMERICAN CENTURY COMPANIES INC trimmed813,285$363M0.3%2026-Q1
WELLS FARGO & COMPANY/MN added744,995$333M0.3%2026-Q1
Swiss National Bank added744,600$332M0.3%2026-Q1
AQR CAPITAL MANAGEMENT LLC added616,170$305M0.3%2026-Q2
CITIGROUP INC added682,807$305M0.3%2026-Q1
Bellevue Group AG added681,908$304M0.3%2026-Q1
BARCLAYS PLC trimmed663,263$296M0.3%2026-Q1
HSBC HOLDINGS PLC added655,443$293M0.3%2026-Q1
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP added638,950$285M0.3%2026-Q1
UBS Group AG added630,618$282M0.2%2026-Q1
Sumitomo Mitsui Trust Group, Inc. trimmed614,448$274M0.2%2026-Q1
MARSHALL WACE, LLP added543,897$270M0.2%2026-Q2
Mitsubishi UFJ Asset Management Co., Ltd. added597,497$267M0.2%2026-Q1
CITADEL ADVISORS LLC added510,430$254M0.2%2026-Q2
Vanguard Global Advisers, LLC new555,733$248M0.2%2026-Q1
NATIXIS ADVISORS, LLC added554,024$247M0.2%2026-Q1
MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed553,243$247M0.2%2026-Q1
NEUBERGER BERMAN GROUP LLC added551,522$246M0.2%2026-Q1
FRANKLIN RESOURCES INC added551,132$246M0.2%2026-Q1
Assenagon Asset Management S.A. trimmed537,248$240M0.2%2026-Q1
National Pension Service added532,069$238M0.2%2026-Q1
VOYA INVESTMENT MANAGEMENT LLC trimmed527,047$235M0.2%2026-Q1
MILLENNIUM MANAGEMENT LLC added468,410$233M0.2%2026-Q2
DekaBank Deutsche Girozentrale506,457$230M0.2%2026-Q1
B. Metzler seel. Sohn & Co. AG trimmed511,036$228M0.2%2026-Q1
ENVESTNET ASSET MANAGEMENT INC added503,564$225M0.2%2026-Q1
California Public Employees Retirement System trimmed503,374$225M0.2%2026-Q1
RAYMOND JAMES FINANCIAL INC added444,496$198M0.2%2026-Q1
VANGUARD ASSET MANAGEMENT, Ltd new442,177$197M0.2%2026-Q1
Life Cycle Investment Partners Ltd added440,409$197M0.2%2026-Q1
Hudson Bay Capital Management LP added390,440$194M0.2%2026-Q2
PRINCIPAL FINANCIAL GROUP INC added426,523$190M0.2%2026-Q1
RHUMBLINE ADVISERS trimmed423,140$189M0.2%2026-Q1
BNP PARIBAS FINANCIAL MARKETS trimmed415,625$186M0.2%2026-Q1
Chevy Chase Trust Holdings, LLC trimmed407,615$182M0.2%2026-Q1
Robeco Institutional Asset Management B.V. added401,644$179M0.2%2026-Q1
BANK OF MONTREAL /CAN/ trimmed390,476$174M0.2%2026-Q1
Zurcher Kantonalbank (Zurich Cantonalbank) added377,013$168M0.1%2026-Q1
ProShare Advisors LLC trimmed373,532$167M0.1%2026-Q1
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM trimmed373,481$167M0.1%2026-Q1
Russell Investments Group, Ltd. trimmed367,691$164M0.1%2026-Q1
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main trimmed364,513$163M0.1%2026-Q1
RENAISSANCE TECHNOLOGIES LLC trimmed320,008$159M0.1%2026-Q2
Universal- Beteiligungs- und Servicegesellschaft mbH added338,347$151M0.1%2026-Q1
Pictet Asset Management Holding SA trimmed337,569$150M0.1%2026-Q1
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ added327,498$149M0.1%2026-Q1
TWO SIGMA INVESTMENTS, LP trimmed285,000$142M0.1%2026-Q2
Bank Julius Baer & Co. Ltd, Zurich trimmed317,406$142M0.1%2026-Q1
Harding Loevner LP trimmed313,546$140M0.1%2026-Q1
AMF Tjanstepension AB added312,917$140M0.1%2026-Q1
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO trimmed311,750$139M0.1%2026-Q1
FIRST TRUST ADVISORS LP added306,461$137M0.1%2026-Q1
BAILLIE GIFFORD & CO added272,561$135M0.1%2026-Q2
Cerity Partners LLC added296,654$132M0.1%2026-Q1
NEW YORK STATE COMMON RETIREMENT FUND trimmed292,414$131M0.1%2026-Q1
NATIONAL BANK OF CANADA /FI/ added272,117$122M0.1%2026-Q1
Swedbank AB added271,553$121M0.1%2026-Q1
VANGUARD GROUP INC trimmed24,105,823$10.9B9.6%2025-Q4 stale
PARNASSUS INVESTMENTS, LLC trimmed1,648,433$646M0.6%2025-Q3 stale
Winslow Capital Management, LLC added887,640$405M0.4%2025-Q4 stale
Artisan Partners Limited Partnership trimmed650,259$289M0.3%2025-Q2 stale
Alyeska Investment Group, L.P. added354,334$161M0.1%2025-Q4 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership