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Institutional Ownership · SEC Form 13F

Who owns Vertex Pharmaceuticals (VRTX)


Which tracked institutional funds hold VRTX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See VRTX company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

1,664
Institutional holders
236M
Shares held (tracked funds)
93.0%
Of shares outstanding

How the tape is positioned

601 tracked funds added or opened VRTX while 229 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

VRTX’s largest tracked holder by dollar value, Capital World Investors, sizes it at 1.5% of its own reported 13F book, while the median holder sizes it at 0.2% of theirs — a 1.4pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in VRTX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 1664 tracked filers holding VRTX, 856 increased or opened the position and 803 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in VRTX between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 51

  • Jupiter Topco LLC$626M
  • Nykredit A/S$123M
  • Harvest Portfolios Group Inc.$74M
  • ADAMS DIVERSIFIED EQUITY FUND, INC.$23M
  • Quadrature Capital Ltd$23M
  • TUDOR INVESTMENT CORP ET AL$15M

Full exits 114

  • JANUS HENDERSON GROUP PLC$952M
  • Amundi$658M
  • NATIXIS ADVISORS, LLC$247M
  • DekaBank Deutsche Girozentrale$230M
  • PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO$139M
  • Handelsbanken Fonder AB$99M

Largest adds

  • Capital World Investors$1.6B
  • BlackRock, Inc.$1.6B
  • Invesco Ltd.$1.6B
  • FRANKLIN RESOURCES INC$1.4B
  • VANGUARD CAPITAL MANAGEMENT LLC$863M
  • STATE STREET CORP$659M

Largest trims

  • ALLIANCEBERNSTEIN L.P.$425M
  • FMR LLC$170M
  • NORGES BANK$155M
  • EDGEWOOD MANAGEMENT LLC$140M
  • Harding Loevner LP$139M
  • B. Metzler seel. Sohn & Co. AG$113M

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
Capital World Investors added26,115,014$13.0B12.2%2026-Q2
BlackRock, Inc. added24,109,373$12.0B11.2%2026-Q2
Capital Research Global Investors trimmed19,490,637$9.7B9.1%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added16,580,713$8.2B7.7%2026-Q2
STATE STREET CORP added11,871,459$5.9B5.5%2026-Q2
Invesco Ltd. added8,043,052$4.0B3.7%2026-Q2
JPMORGAN CHASE & CO trimmed6,517,600$3.3B3.1%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC trimmed6,017,848$3.0B2.8%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC trimmed4,878,987$2.4B2.3%2026-Q2
Capital International Investors trimmed4,695,144$2.3B2.2%2026-Q2
LOOMIS SAYLES & CO L P trimmed3,920,953$1.9B1.8%2026-Q2
FRANKLIN RESOURCES INC added3,347,253$1.7B1.6%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP added3,247,658$1.6B1.5%2026-Q2
MORGAN STANLEY added3,242,139$1.6B1.5%2026-Q2
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added3,086,683$1.5B1.4%2026-Q2
BANK OF AMERICA CORP /DE/ added3,039,178$1.5B1.4%2026-Q2
ALLIANCEBERNSTEIN L.P. trimmed3,019,315$1.3B1.3%2026-Q2
JENNISON ASSOCIATES LLC added2,998,530$1.5B1.4%2026-Q2
NORGES BANK trimmed2,971,681$1.5B1.4%2026-Q2
AMERIPRISE FINANCIAL INC trimmed2,604,822$1.3B1.2%2026-Q2
NORTHERN TRUST CORP trimmed2,486,478$1.2B1.2%2026-Q2
GOLDMAN SACHS GROUP INC added2,481,761$1.2B1.2%2026-Q2
Clearbridge Investments, LLC trimmed2,342,915$1.2B1.1%2026-Q2
VICTORY CAPITAL MANAGEMENT INC added2,173,152$1.1B1.0%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added2,041,282$1.0B1.0%2026-Q2
Legal & General Group Plc trimmed1,870,015$929M0.9%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ trimmed1,728,421$859M0.8%2026-Q2
Bank of New York Mellon Corp added1,672,623$831M0.8%2026-Q2
DEUTSCHE BANK AG\ added1,579,110$784M0.7%2026-Q2
FMR LLC trimmed1,457,158$724M0.7%2026-Q2
VANGUARD FIDUCIARY TRUST CO trimmed1,425,390$708M0.7%2026-Q2
Jupiter Topco LLC new1,259,997$626M0.6%2026-Q2
DIMENSIONAL FUND ADVISORS LP added1,168,956$581M0.5%2026-Q2
WCM INVESTMENT MANAGEMENT, LLC added1,152,094$576M0.5%2026-Q2
Nuveen, LLC trimmed1,081,685$537M0.5%2026-Q2
ROYAL BANK OF CANADA trimmed980,259$487M0.5%2026-Q2
BNP PARIBAS ASSET MANAGEMENT Holding S.A. added897,893$446M0.4%2026-Q2
Assenagon Asset Management S.A. added759,564$377M0.4%2026-Q2
WELLS FARGO & COMPANY/MN added749,528$372M0.3%2026-Q2
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP added738,378$367M0.3%2026-Q2
BARCLAYS PLC added733,274$364M0.3%2026-Q2
Swiss National Bank trimmed717,440$356M0.3%2026-Q2
UBS Group AG added712,259$354M0.3%2026-Q2
CITIGROUP INC added706,968$351M0.3%2026-Q2
HSBC HOLDINGS PLC added676,247$336M0.3%2026-Q2
Mitsubishi UFJ Asset Management Co., Ltd. added647,193$321M0.3%2026-Q2
AQR CAPITAL MANAGEMENT LLC added616,170$305M0.3%2026-Q2
Sumitomo Mitsui Trust Group, Inc. trimmed611,907$304M0.3%2026-Q2
AMERICAN CENTURY COMPANIES INC trimmed580,901$289M0.3%2026-Q2
Bellevue Group AG trimmed578,634$287M0.3%2026-Q2
NEUBERGER BERMAN GROUP LLC added559,445$278M0.3%2026-Q2
RAYMOND JAMES FINANCIAL INC added556,876$277M0.3%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE added554,085$275M0.3%2026-Q2
Vanguard Global Advisers, LLC trimmed547,463$272M0.3%2026-Q2
MARSHALL WACE, LLP added543,897$270M0.3%2026-Q2
National Pension Service added539,530$268M0.3%2026-Q2
Pictet Asset Management Holding SA added539,255$268M0.3%2026-Q2
EDGEWOOD MANAGEMENT LLC trimmed531,003$264M0.2%2026-Q2
Life Cycle Investment Partners Ltd added514,179$255M0.2%2026-Q2
CITADEL ADVISORS LLC added510,430$254M0.2%2026-Q2
VOYA INVESTMENT MANAGEMENT LLC trimmed505,219$250M0.2%2026-Q2
VANGUARD ASSET MANAGEMENT, Ltd added494,186$245M0.2%2026-Q2
ENVESTNET ASSET MANAGEMENT INC trimmed487,627$242M0.2%2026-Q2
MILLENNIUM MANAGEMENT LLC added468,410$233M0.2%2026-Q2
California Public Employees Retirement System trimmed447,499$222M0.2%2026-Q2
BANK OF MONTREAL /CAN/ added427,448$212M0.2%2026-Q2
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ added423,049$215M0.2%2026-Q2
Chevy Chase Trust Holdings, LLC trimmed406,303$202M0.2%2026-Q2
Robeco Institutional Asset Management B.V. added404,396$201M0.2%2026-Q2
RHUMBLINE ADVISERS trimmed396,380$197M0.2%2026-Q2
ADAGE CAPITAL PARTNERS GP, L.L.C. added393,964$196M0.2%2026-Q2
Hudson Bay Capital Management LP added390,440$194M0.2%2026-Q2
PRINCIPAL FINANCIAL GROUP INC trimmed389,511$193M0.2%2026-Q2
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added383,491$190M0.2%2026-Q2
Zurcher Kantonalbank (Zurich Cantonalbank) added380,762$189M0.2%2026-Q2
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main trimmed359,332$178M0.2%2026-Q2
CANADA PENSION PLAN INVESTMENT BOARD added355,082$176M0.2%2026-Q2
Russell Investments Group, Ltd. trimmed336,990$168M0.2%2026-Q2
Universal- Beteiligungs- und Servicegesellschaft mbH trimmed323,752$161M0.2%2026-Q2
RENAISSANCE TECHNOLOGIES LLC trimmed320,008$159M0.1%2026-Q2
Bank Julius Baer & Co. Ltd, Zurich added319,371$159M0.1%2026-Q2
AMF Tjanstepension AB added314,765$156M0.1%2026-Q2
FIRST TRUST ADVISORS LP trimmed289,179$144M0.1%2026-Q2
LPL Financial LLC added289,111$144M0.1%2026-Q2
ProShare Advisors LLC trimmed287,847$143M0.1%2026-Q2
TWO SIGMA INVESTMENTS, LP trimmed285,000$142M0.1%2026-Q2
Swedbank AB added282,444$140M0.1%2026-Q2
NEW YORK STATE COMMON RETIREMENT FUND trimmed277,614$138M0.1%2026-Q2
BAILLIE GIFFORD & CO added272,561$135M0.1%2026-Q2
BNP PARIBAS FINANCIAL MARKETS trimmed262,258$130M0.1%2026-Q2
Cerity Partners LLC trimmed255,874$127M0.1%2026-Q2
Nykredit A/S new248,068$123M0.1%2026-Q2
ROYAL LONDON ASSET MANAGEMENT LTD trimmed241,280$120M0.1%2026-Q2
B. Metzler seel. Sohn & Co. AG trimmed231,381$115M0.1%2026-Q2
AVIVA PLC added223,593$111M0.1%2026-Q2
ING GROEP NV added223,124$111M0.1%2026-Q2
Welch & Forbes LLC added221,304$110M0.1%2026-Q2
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM trimmed219,813$109M0.1%2026-Q2
JONES FINANCIAL COMPANIES LLLP added215,419$106M0.1%2026-Q2
Korea Investment CORP added213,312$106M0.1%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership