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Institutional Ownership · SEC Form 13F

Who owns Twist Bioscience Corporation (TWST)


Which tracked institutional funds hold TWST, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See TWST company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

281
Institutional holders
74M
Shares held (tracked funds)

How the tape is positioned

The tracked-fund tape on TWST is one-sided between 2025-Q4 and 2026-Q1: 129 added or opened and 29 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

TWST’s largest tracked holder by dollar value, Artisan Partners Limited Partnership, sizes it at 0.5% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.5pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in TWST divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 281 tracked filers holding TWST, 149 increased or opened the position and 124 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in TWST between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 30

  • VANGUARD PORTFOLIO MANAGEMENT LLC$126M
  • VANGUARD CAPITAL MANAGEMENT LLC$125M
  • Point72 Asset Management, L.P.$32M
  • JANE STREET GROUP, LLC$29M
  • Driehaus Capital Management LLC$28M
  • LOOMIS SAYLES & CO L P$23M

Full exits 16

  • VANGUARD GROUP INC$167M
  • JUPITER ASSET MANAGEMENT LTD$8M
  • Qube Research & Technologies Ltd$5M
  • NATIXIS$3M
  • JACOBS LEVY EQUITY MANAGEMENT, INC$3M
  • Aquatic Capital Management LLC$2M

Largest adds

  • Artisan Partners Limited Partnership$118M
  • EdgePoint Investment Group Inc.$85M
  • FMR LLC$84M
  • FARALLON CAPITAL MANAGEMENT LLC$68M
  • ARK Investment Management LLC$62M
  • WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC$62M

Largest trims

  • BlackRock, Inc.$55M
  • MILLENNIUM MANAGEMENT LLC$31M
  • AMERICAN CENTURY COMPANIES INC$26M
  • STEMPOINT CAPITAL LP$14M
  • Aberdeen Group plc$6M
  • BARCLAYS PLC$6M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
Artisan Partners Limited Partnership added6,367,777$303M8.2%2026-Q1
ARK Investment Management LLC trimmed6,342,733$301M8.2%2026-Q1
EdgePoint Investment Group Inc. added5,382,521$256M7.0%2026-Q1
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC trimmed5,269,718$250M6.8%2026-Q1
STATE STREET CORP added3,670,682$174M4.8%2026-Q1
BlackRock, Inc. trimmed2,767,058$131M3.6%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new2,649,101$126M3.4%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new2,639,044$125M3.4%2026-Q1
Invesco Ltd. added2,033,802$97M2.6%2026-Q1
FMR LLC added1,822,301$87M2.4%2026-Q1
GOLDMAN SACHS GROUP INC added1,705,546$81M2.2%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added1,519,713$72M2.0%2026-Q1
Sumitomo Mitsui Trust Group, Inc. trimmed1,496,099$71M1.9%2026-Q1
Amova Asset Management Americas, Inc. trimmed1,496,099$71M1.9%2026-Q1
FARALLON CAPITAL MANAGEMENT LLC added1,427,650$68M1.8%2026-Q1
Thrivent Financial for Lutherans trimmed1,312,544$62M1.7%2026-Q1
Soleus Capital Management, L.P. trimmed1,226,629$58M1.6%2026-Q1
CITADEL ADVISORS LLC added1,220,400$58M1.6%2026-Q1
BAILLIE GIFFORD & CO trimmed1,215,151$58M1.6%2026-Q1
First Light Asset Management, LLC trimmed878,848$42M1.1%2026-Q1
Tao Capital Management LP828,815$39M1.1%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed823,976$39M1.1%2026-Q1
DIMENSIONAL FUND ADVISORS LP trimmed781,618$37M1.0%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. added726,288$35M0.9%2026-Q1
WELLINGTON MANAGEMENT GROUP LLP trimmed709,421$34M0.9%2026-Q1
NEW YORK STATE COMMON RETIREMENT FUND added673,987$32M0.9%2026-Q1
Point72 Asset Management, L.P. added669,732$32M0.9%2026-Q1
JENNISON ASSOCIATES LLC trimmed605,188$29M0.8%2026-Q1
BNP PARIBAS FINANCIAL MARKETS added604,047$29M0.8%2026-Q1
JANE STREET GROUP, LLC added601,163$29M0.8%2026-Q1
Driehaus Capital Management LLC added584,696$28M0.8%2026-Q1
BANK OF AMERICA CORP /DE/ added584,261$28M0.8%2026-Q1
MORGAN STANLEY trimmed546,845$26M0.7%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed537,111$26M0.7%2026-Q1
NORTHERN TRUST CORP added527,966$25M0.7%2026-Q1
LOOMIS SAYLES & CO L P new492,290$23M0.6%2026-Q1
Allspring Global Investments Holdings, LLC added455,446$23M0.6%2026-Q1
CITIGROUP INC added460,287$22M0.6%2026-Q1
UBS Group AG trimmed452,526$22M0.6%2026-Q1
VANGUARD FIDUCIARY TRUST CO new423,115$20M0.5%2026-Q1
SEI INVESTMENTS CO added354,420$17M0.5%2026-Q1
MILLENNIUM MANAGEMENT LLC trimmed350,604$17M0.5%2026-Q1
Holocene Advisors, LP added344,758$16M0.4%2026-Q1
Nuveen, LLC added293,655$14M0.4%2026-Q1
IQ EQ FUND MANAGEMENT (IRELAND) Ltd trimmed284,589$14M0.4%2026-Q1
Blue Water Life Science Advisors, LP trimmed276,000$13M0.4%2026-Q1
Freshford Capital Management, LLC trimmed258,982$12M0.3%2026-Q1
Schonfeld Strategic Advisors LLC added258,604$12M0.3%2026-Q1
SILVERCREST ASSET MANAGEMENT GROUP LLC trimmed244,025$12M0.3%2026-Q1
Meridiem Capital Partners LP added239,669$11M0.3%2026-Q1
PEREGRINE CAPITAL MANAGEMENT LLC trimmed220,079$10M0.3%2026-Q1
OSTERWEIS CAPITAL MANAGEMENT INC trimmed211,158$10M0.3%2026-Q1
Duquesne Family Office LLC new206,000$10M0.3%2026-Q1
JPMORGAN CHASE & CO trimmed205,767$9M0.2%2026-Q1
Bank of New York Mellon Corp trimmed180,817$9M0.2%2026-Q1
Pictet Asset Management Holding SA trimmed185,992$8M0.2%2026-Q1
Trexquant Investment LP trimmed170,107$8M0.2%2026-Q1
Squarepoint Ops LLC added153,526$7M0.2%2026-Q1
STATE OF MICHIGAN RETIREMENT SYSTEM153,172$7M0.2%2026-Q1
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. added152,687$7M0.2%2026-Q1
PERCEPTIVE ADVISORS LLC added150,000$7M0.2%2026-Q1
ODDO BHF ASSET MANAGEMENT SAS added145,960$7M0.2%2026-Q1
Universal- Beteiligungs- und Servicegesellschaft mbH added131,265$6M0.2%2026-Q1
Legal & General Group Plc trimmed128,075$6M0.2%2026-Q1
AQR CAPITAL MANAGEMENT LLC trimmed122,813$6M0.2%2026-Q1
Swiss National Bank119,000$6M0.2%2026-Q1
Vestmark Advisory Solutions, Inc. trimmed109,266$5M0.1%2026-Q1
NEUBERGER BERMAN GROUP LLC trimmed108,300$5M0.1%2026-Q1
Clearstead Advisors, LLC added107,303$5M0.1%2026-Q1
PRINCIPAL FINANCIAL GROUP INC added106,712$5M0.1%2026-Q1
FIRST TRUST ADVISORS LP added104,650$5M0.1%2026-Q1
Metavasi Capital LP new100,000$5M0.1%2026-Q1
LORD, ABBETT & CO. LLC trimmed99,630$5M0.1%2026-Q1
Man Group plc added96,470$5M0.1%2026-Q1
Rafferty Asset Management, LLC trimmed96,255$5M0.1%2026-Q1
FRED ALGER MANAGEMENT, LLC added95,783$5M0.1%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP added90,319$4M0.1%2026-Q1
RHUMBLINE ADVISERS trimmed90,044$4M0.1%2026-Q1
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added79,078$4M0.1%2026-Q1
Ensign Peak Advisors, Inc trimmed75,012$4M0.1%2026-Q1
Aberdeen Group plc trimmed73,619$3M0.1%2026-Q1
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added70,348$3M0.1%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ added70,305$3M0.1%2026-Q1
NORGES BANK trimmed82,378$3M0.1%2026-Q1
Russell Investments Group, Ltd. added66,565$3M0.1%2026-Q1
ENVESTNET ASSET MANAGEMENT INC added65,556$3M0.1%2026-Q1
DEUTSCHE BANK AG\ added64,536$3M0.1%2026-Q1
LAZARD ASSET MANAGEMENT LLC trimmed57,628$3M0.1%2026-Q1
BLAIR WILLIAM & CO/IL trimmed57,417$3M0.1%2026-Q1
VANGUARD GROUP INC trimmed5,274,441$167M4.6%2025-Q4 stale
ExodusPoint Capital Management, LP added471,829$17M0.5%2025-Q2 stale
Iron Triangle Partners LP added424,355$16M0.4%2025-Q2 stale
MPM BIOIMPACT LLC trimmed261,215$10M0.3%2025-Q1 stale
HAWK RIDGE CAPITAL MANAGEMENT LP added234,300$9M0.2%2025-Q2 stale
JUPITER ASSET MANAGEMENT LTD trimmed243,669$8M0.2%2025-Q4 stale
INTRINSIC EDGE CAPITAL MANAGEMENT LLC trimmed140,000$5M0.1%2025-Q1 stale
Qube Research & Technologies Ltd trimmed171,972$5M0.1%2025-Q4 stale
NATIXIS added103,688$3M0.1%2025-Q4 stale
JACOBS LEVY EQUITY MANAGEMENT, INC trimmed103,117$3M0.1%2025-Q4 stale
Hillsdale Investment Management Inc. trimmed77,600$3M0.1%2025-Q2 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

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