Who owns Twist Bioscience Corporation (TWST)
Which tracked institutional funds hold TWST, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See TWST company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on TWST is one-sided between 2025-Q4 and 2026-Q1: 129 added or opened and 29 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
TWST’s largest tracked holder by dollar value, Artisan Partners Limited Partnership, sizes it at 0.5% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.5pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in TWST divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 281 tracked filers holding TWST, 149 increased or opened the position and 124 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in TWST between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 30
- VANGUARD PORTFOLIO MANAGEMENT LLC$126M
- VANGUARD CAPITAL MANAGEMENT LLC$125M
- Point72 Asset Management, L.P.$32M
- JANE STREET GROUP, LLC$29M
- Driehaus Capital Management LLC$28M
- LOOMIS SAYLES & CO L P$23M
Full exits 16
- VANGUARD GROUP INC$167M
- JUPITER ASSET MANAGEMENT LTD$8M
- Qube Research & Technologies Ltd$5M
- NATIXIS$3M
- JACOBS LEVY EQUITY MANAGEMENT, INC$3M
- Aquatic Capital Management LLC$2M
Largest adds
- Artisan Partners Limited Partnership$118M
- EdgePoint Investment Group Inc.$85M
- FMR LLC$84M
- FARALLON CAPITAL MANAGEMENT LLC$68M
- ARK Investment Management LLC$62M
- WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC$62M
Largest trims
- BlackRock, Inc.$55M
- MILLENNIUM MANAGEMENT LLC$31M
- AMERICAN CENTURY COMPANIES INC$26M
- STEMPOINT CAPITAL LP$14M
- Aberdeen Group plc$6M
- BARCLAYS PLC$6M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Artisan Partners Limited Partnership added | 6,367,777 | $303M | 8.2% | 2026-Q1 |
| ARK Investment Management LLC trimmed | 6,342,733 | $301M | 8.2% | 2026-Q1 |
| EdgePoint Investment Group Inc. added | 5,382,521 | $256M | 7.0% | 2026-Q1 |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC trimmed | 5,269,718 | $250M | 6.8% | 2026-Q1 |
| STATE STREET CORP added | 3,670,682 | $174M | 4.8% | 2026-Q1 |
| BlackRock, Inc. trimmed | 2,767,058 | $131M | 3.6% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 2,649,101 | $126M | 3.4% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 2,639,044 | $125M | 3.4% | 2026-Q1 |
| Invesco Ltd. added | 2,033,802 | $97M | 2.6% | 2026-Q1 |
| FMR LLC added | 1,822,301 | $87M | 2.4% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 1,705,546 | $81M | 2.2% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,519,713 | $72M | 2.0% | 2026-Q1 |
| Sumitomo Mitsui Trust Group, Inc. trimmed | 1,496,099 | $71M | 1.9% | 2026-Q1 |
| Amova Asset Management Americas, Inc. trimmed | 1,496,099 | $71M | 1.9% | 2026-Q1 |
| FARALLON CAPITAL MANAGEMENT LLC added | 1,427,650 | $68M | 1.8% | 2026-Q1 |
| Thrivent Financial for Lutherans trimmed | 1,312,544 | $62M | 1.7% | 2026-Q1 |
| Soleus Capital Management, L.P. trimmed | 1,226,629 | $58M | 1.6% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 1,220,400 | $58M | 1.6% | 2026-Q1 |
| BAILLIE GIFFORD & CO trimmed | 1,215,151 | $58M | 1.6% | 2026-Q1 |
| First Light Asset Management, LLC trimmed | 878,848 | $42M | 1.1% | 2026-Q1 |
| Tao Capital Management LP | 828,815 | $39M | 1.1% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 823,976 | $39M | 1.1% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP trimmed | 781,618 | $37M | 1.0% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. added | 726,288 | $35M | 0.9% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 709,421 | $34M | 0.9% | 2026-Q1 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 673,987 | $32M | 0.9% | 2026-Q1 |
| Point72 Asset Management, L.P. added | 669,732 | $32M | 0.9% | 2026-Q1 |
| JENNISON ASSOCIATES LLC trimmed | 605,188 | $29M | 0.8% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 604,047 | $29M | 0.8% | 2026-Q1 |
| JANE STREET GROUP, LLC added | 601,163 | $29M | 0.8% | 2026-Q1 |
| Driehaus Capital Management LLC added | 584,696 | $28M | 0.8% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 584,261 | $28M | 0.8% | 2026-Q1 |
| MORGAN STANLEY trimmed | 546,845 | $26M | 0.7% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed | 537,111 | $26M | 0.7% | 2026-Q1 |
| NORTHERN TRUST CORP added | 527,966 | $25M | 0.7% | 2026-Q1 |
| LOOMIS SAYLES & CO L P new | 492,290 | $23M | 0.6% | 2026-Q1 |
| Allspring Global Investments Holdings, LLC added | 455,446 | $23M | 0.6% | 2026-Q1 |
| CITIGROUP INC added | 460,287 | $22M | 0.6% | 2026-Q1 |
| UBS Group AG trimmed | 452,526 | $22M | 0.6% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 423,115 | $20M | 0.5% | 2026-Q1 |
| SEI INVESTMENTS CO added | 354,420 | $17M | 0.5% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC trimmed | 350,604 | $17M | 0.5% | 2026-Q1 |
| Holocene Advisors, LP added | 344,758 | $16M | 0.4% | 2026-Q1 |
| Nuveen, LLC added | 293,655 | $14M | 0.4% | 2026-Q1 |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd trimmed | 284,589 | $14M | 0.4% | 2026-Q1 |
| Blue Water Life Science Advisors, LP trimmed | 276,000 | $13M | 0.4% | 2026-Q1 |
| Freshford Capital Management, LLC trimmed | 258,982 | $12M | 0.3% | 2026-Q1 |
| Schonfeld Strategic Advisors LLC added | 258,604 | $12M | 0.3% | 2026-Q1 |
| SILVERCREST ASSET MANAGEMENT GROUP LLC trimmed | 244,025 | $12M | 0.3% | 2026-Q1 |
| Meridiem Capital Partners LP added | 239,669 | $11M | 0.3% | 2026-Q1 |
| PEREGRINE CAPITAL MANAGEMENT LLC trimmed | 220,079 | $10M | 0.3% | 2026-Q1 |
| OSTERWEIS CAPITAL MANAGEMENT INC trimmed | 211,158 | $10M | 0.3% | 2026-Q1 |
| Duquesne Family Office LLC new | 206,000 | $10M | 0.3% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 205,767 | $9M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp trimmed | 180,817 | $9M | 0.2% | 2026-Q1 |
| Pictet Asset Management Holding SA trimmed | 185,992 | $8M | 0.2% | 2026-Q1 |
| Trexquant Investment LP trimmed | 170,107 | $8M | 0.2% | 2026-Q1 |
| Squarepoint Ops LLC added | 153,526 | $7M | 0.2% | 2026-Q1 |
| STATE OF MICHIGAN RETIREMENT SYSTEM | 153,172 | $7M | 0.2% | 2026-Q1 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. added | 152,687 | $7M | 0.2% | 2026-Q1 |
| PERCEPTIVE ADVISORS LLC added | 150,000 | $7M | 0.2% | 2026-Q1 |
| ODDO BHF ASSET MANAGEMENT SAS added | 145,960 | $7M | 0.2% | 2026-Q1 |
| Universal- Beteiligungs- und Servicegesellschaft mbH added | 131,265 | $6M | 0.2% | 2026-Q1 |
| Legal & General Group Plc trimmed | 128,075 | $6M | 0.2% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 122,813 | $6M | 0.2% | 2026-Q1 |
| Swiss National Bank | 119,000 | $6M | 0.2% | 2026-Q1 |
| Vestmark Advisory Solutions, Inc. trimmed | 109,266 | $5M | 0.1% | 2026-Q1 |
| NEUBERGER BERMAN GROUP LLC trimmed | 108,300 | $5M | 0.1% | 2026-Q1 |
| Clearstead Advisors, LLC added | 107,303 | $5M | 0.1% | 2026-Q1 |
| PRINCIPAL FINANCIAL GROUP INC added | 106,712 | $5M | 0.1% | 2026-Q1 |
| FIRST TRUST ADVISORS LP added | 104,650 | $5M | 0.1% | 2026-Q1 |
| Metavasi Capital LP new | 100,000 | $5M | 0.1% | 2026-Q1 |
| LORD, ABBETT & CO. LLC trimmed | 99,630 | $5M | 0.1% | 2026-Q1 |
| Man Group plc added | 96,470 | $5M | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC trimmed | 96,255 | $5M | 0.1% | 2026-Q1 |
| FRED ALGER MANAGEMENT, LLC added | 95,783 | $5M | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 90,319 | $4M | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS trimmed | 90,044 | $4M | 0.1% | 2026-Q1 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 79,078 | $4M | 0.1% | 2026-Q1 |
| Ensign Peak Advisors, Inc trimmed | 75,012 | $4M | 0.1% | 2026-Q1 |
| Aberdeen Group plc trimmed | 73,619 | $3M | 0.1% | 2026-Q1 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 70,348 | $3M | 0.1% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 70,305 | $3M | 0.1% | 2026-Q1 |
| NORGES BANK trimmed | 82,378 | $3M | 0.1% | 2026-Q1 |
| Russell Investments Group, Ltd. added | 66,565 | $3M | 0.1% | 2026-Q1 |
| ENVESTNET ASSET MANAGEMENT INC added | 65,556 | $3M | 0.1% | 2026-Q1 |
| DEUTSCHE BANK AG\ added | 64,536 | $3M | 0.1% | 2026-Q1 |
| LAZARD ASSET MANAGEMENT LLC trimmed | 57,628 | $3M | 0.1% | 2026-Q1 |
| BLAIR WILLIAM & CO/IL trimmed | 57,417 | $3M | 0.1% | 2026-Q1 |
| VANGUARD GROUP INC trimmed | 5,274,441 | $167M | 4.6% | 2025-Q4 stale |
| ExodusPoint Capital Management, LP added | 471,829 | $17M | 0.5% | 2025-Q2 stale |
| Iron Triangle Partners LP added | 424,355 | $16M | 0.4% | 2025-Q2 stale |
| MPM BIOIMPACT LLC trimmed | 261,215 | $10M | 0.3% | 2025-Q1 stale |
| HAWK RIDGE CAPITAL MANAGEMENT LP added | 234,300 | $9M | 0.2% | 2025-Q2 stale |
| JUPITER ASSET MANAGEMENT LTD trimmed | 243,669 | $8M | 0.2% | 2025-Q4 stale |
| INTRINSIC EDGE CAPITAL MANAGEMENT LLC trimmed | 140,000 | $5M | 0.1% | 2025-Q1 stale |
| Qube Research & Technologies Ltd trimmed | 171,972 | $5M | 0.1% | 2025-Q4 stale |
| NATIXIS added | 103,688 | $3M | 0.1% | 2025-Q4 stale |
| JACOBS LEVY EQUITY MANAGEMENT, INC trimmed | 103,117 | $3M | 0.1% | 2025-Q4 stale |
| Hillsdale Investment Management Inc. trimmed | 77,600 | $3M | 0.1% | 2025-Q2 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.