Who owns Twist Bioscience (TWST)
Which tracked institutional funds hold TWST, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See TWST company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on TWST is one-sided between 2026-Q1 and 2026-Q2: 184 added or opened and 28 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
TWST’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes TWST more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in TWST divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 317 tracked filers holding TWST, 177 increased or opened the position and 149 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in TWST between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 38
- Stephens Investment Management Group LLC$79M
- FIL Ltd$66M
- MARSHALL WACE, LLP$41M
- Granahan Investment Management, LLC$32M
- FEDERATED HERMES, INC.$31M
- USS Investment Management Ltd$25M
Full exits 17
- Thrivent Financial for Lutherans$62M
- Point72 Asset Management, L.P.$32M
- Holocene Advisors, LP$16M
- Blue Water Life Science Advisors, LP$13M
- Schonfeld Strategic Advisors LLC$12M
- Meridiem Capital Partners LP$11M
Largest adds
- BlackRock, Inc.$469M
- FMR LLC$397M
- PRICE T ROWE ASSOCIATES INC /MD/$371M
- Artisan Partners Limited Partnership$191M
- ARK Investment Management LLC$167M
- VANGUARD PORTFOLIO MANAGEMENT LLC$165M
Largest trims
- Soleus Capital Management, L.P.$48M
- BALYASNY ASSET MANAGEMENT L.P.$34M
- WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC$27M
- JANE STREET GROUP, LLC$20M
- CITIGROUP INC$14M
- PERCEPTIVE ADVISORS LLC$3M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| BlackRock, Inc. added | 5,833,891 | $600M | 8.1% | 2026-Q2 |
| Artisan Partners Limited Partnership trimmed | 4,802,017 | $494M | 6.7% | 2026-Q2 |
| FMR LLC added | 4,703,044 | $484M | 6.6% | 2026-Q2 |
| ARK Investment Management LLC trimmed | 4,549,803 | $468M | 6.4% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 3,634,652 | $374M | 5.1% | 2026-Q2 |
| STATE STREET CORP trimmed | 3,232,532 | $333M | 4.5% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 2,824,989 | $291M | 3.9% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 2,699,280 | $278M | 3.8% | 2026-Q2 |
| EdgePoint Investment Group Inc. trimmed | 2,521,635 | $259M | 3.5% | 2026-Q2 |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC trimmed | 2,174,594 | $224M | 3.0% | 2026-Q2 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. added | 2,136,400 | $220M | 3.0% | 2026-Q2 |
| Invesco Ltd. trimmed | 1,928,229 | $198M | 2.7% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,619,361 | $167M | 2.3% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC trimmed | 1,408,418 | $145M | 2.0% | 2026-Q2 |
| MORGAN STANLEY added | 1,189,861 | $122M | 1.7% | 2026-Q2 |
| D. E. Shaw & Co., Inc. added | 1,185,605 | $122M | 1.7% | 2026-Q2 |
| BAILLIE GIFFORD & CO trimmed | 1,086,779 | $112M | 1.5% | 2026-Q2 |
| Driehaus Capital Management LLC added | 1,022,526 | $105M | 1.4% | 2026-Q2 |
| Sumitomo Mitsui Trust Group, Inc. trimmed | 1,000,344 | $103M | 1.4% | 2026-Q2 |
| Amova Asset Management Americas, Inc. trimmed | 999,734 | $103M | 1.4% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 922,647 | $95M | 1.3% | 2026-Q2 |
| CITADEL ADVISORS LLC trimmed | 862,042 | $89M | 1.2% | 2026-Q2 |
| LOOMIS SAYLES & CO L P added | 861,309 | $89M | 1.2% | 2026-Q2 |
| Stephens Investment Management Group LLC new | 767,364 | $79M | 1.1% | 2026-Q2 |
| First Light Asset Management, LLC trimmed | 727,933 | $75M | 1.0% | 2026-Q2 |
| VOYA INVESTMENT MANAGEMENT LLC added | 671,866 | $69M | 0.9% | 2026-Q2 |
| FIL Ltd new | 641,096 | $66M | 0.9% | 2026-Q2 |
| NORTHERN TRUST CORP added | 591,688 | $61M | 0.8% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP trimmed | 582,702 | $60M | 0.8% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 568,347 | $58M | 0.8% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 563,782 | $58M | 0.8% | 2026-Q2 |
| FRED ALGER MANAGEMENT, LLC added | 558,157 | $57M | 0.8% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 557,131 | $57M | 0.8% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS trimmed | 546,647 | $56M | 0.8% | 2026-Q2 |
| Nuveen, LLC added | 522,043 | $54M | 0.7% | 2026-Q2 |
| AMERICAN CENTURY COMPANIES INC added | 487,031 | $50M | 0.7% | 2026-Q2 |
| Tao Capital Management LP trimmed | 478,815 | $49M | 0.7% | 2026-Q2 |
| NEW YORK STATE COMMON RETIREMENT FUND trimmed | 462,145 | $48M | 0.6% | 2026-Q2 |
| JENNISON ASSOCIATES LLC trimmed | 453,216 | $47M | 0.6% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 443,474 | $46M | 0.6% | 2026-Q2 |
| Allspring Global Investments Holdings, LLC trimmed | 418,129 | $43M | 0.6% | 2026-Q2 |
| UBS Group AG trimmed | 413,127 | $43M | 0.6% | 2026-Q2 |
| MARSHALL WACE, LLP added | 396,912 | $41M | 0.6% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 347,148 | $36M | 0.5% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC added | 340,072 | $35M | 0.5% | 2026-Q2 |
| Granahan Investment Management, LLC new | 314,882 | $32M | 0.4% | 2026-Q2 |
| FEDERATED HERMES, INC. added | 298,113 | $31M | 0.4% | 2026-Q2 |
| SEI INVESTMENTS CO trimmed | 294,931 | $30M | 0.4% | 2026-Q2 |
| BLAIR WILLIAM & CO/IL added | 256,556 | $26M | 0.4% | 2026-Q2 |
| Trexquant Investment LP added | 255,271 | $26M | 0.4% | 2026-Q2 |
| USS Investment Management Ltd new | 241,224 | $25M | 0.3% | 2026-Q2 |
| JPMORGAN CHASE & CO trimmed | 205,248 | $20M | 0.3% | 2026-Q2 |
| SILVERCREST ASSET MANAGEMENT GROUP LLC trimmed | 196,496 | $20M | 0.3% | 2026-Q2 |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd trimmed | 191,845 | $20M | 0.3% | 2026-Q2 |
| Bank of New York Mellon Corp added | 191,698 | $20M | 0.3% | 2026-Q2 |
| FIRST TRUST ADVISORS LP added | 190,879 | $20M | 0.3% | 2026-Q2 |
| Freshford Capital Management, LLC trimmed | 177,449 | $18M | 0.2% | 2026-Q2 |
| STATE OF MICHIGAN RETIREMENT SYSTEM added | 177,401 | $18M | 0.2% | 2026-Q2 |
| Metavasi Capital LP added | 176,004 | $18M | 0.2% | 2026-Q2 |
| Universal- Beteiligungs- und Servicegesellschaft mbH added | 153,667 | $16M | 0.2% | 2026-Q2 |
| NEUBERGER BERMAN GROUP LLC added | 145,642 | $15M | 0.2% | 2026-Q2 |
| ARMISTICE CAPITAL, LLC new | 142,000 | $15M | 0.2% | 2026-Q2 |
| PEREGRINE CAPITAL MANAGEMENT LLC trimmed | 138,970 | $14M | 0.2% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC added | 129,391 | $13M | 0.2% | 2026-Q2 |
| Science & Technology Partners, L.P. new | 129,228 | $13M | 0.2% | 2026-Q2 |
| Legal & General Group Plc trimmed | 121,980 | $13M | 0.2% | 2026-Q2 |
| PARNASSUS INVESTMENTS, LLC new | 120,001 | $12M | 0.2% | 2026-Q2 |
| Swiss National Bank trimmed | 113,800 | $12M | 0.2% | 2026-Q2 |
| OSTERWEIS CAPITAL MANAGEMENT INC trimmed | 111,458 | $11M | 0.2% | 2026-Q2 |
| Pictet Asset Management Holding SA trimmed | 108,267 | $11M | 0.1% | 2026-Q2 |
| Atika Capital Management LLC new | 108,000 | $11M | 0.2% | 2026-Q2 |
| Soleus Capital Management, L.P. trimmed | 104,629 | $11M | 0.1% | 2026-Q2 |
| TD Asset Management Inc added | 103,986 | $11M | 0.1% | 2026-Q2 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 100,108 | $10M | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 99,388 | $10M | 0.1% | 2026-Q2 |
| Mawer Investment Management Ltd. new | 99,251 | $10M | 0.1% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 97,616 | $10M | 0.1% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP added | 94,600 | $10M | 0.1% | 2026-Q2 |
| DEUTSCHE BANK AG\ added | 90,053 | $9M | 0.1% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. trimmed | 89,273 | $9M | 0.1% | 2026-Q2 |
| ODDO BHF ASSET MANAGEMENT SAS trimmed | 88,006 | $9M | 0.1% | 2026-Q2 |
| JANE STREET GROUP, LLC trimmed | 86,284 | $9M | 0.1% | 2026-Q2 |
| Vestmark Advisory Solutions, Inc. trimmed | 85,142 | $9M | 0.1% | 2026-Q2 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE added | 79,848 | $8M | 0.1% | 2026-Q2 |
| CITIGROUP INC trimmed | 77,626 | $8M | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 77,336 | $8M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 75,529 | $8M | 0.1% | 2026-Q2 |
| Ensign Peak Advisors, Inc trimmed | 74,314 | $8M | 0.1% | 2026-Q2 |
| ENVESTNET ASSET MANAGEMENT INC added | 66,627 | $7M | 0.1% | 2026-Q2 |
| LPL Financial LLC added | 63,897 | $7M | 0.1% | 2026-Q2 |
| Informed Momentum Co LLC new | 62,564 | $6M | 0.1% | 2026-Q2 |
| PRINCIPAL FINANCIAL GROUP INC trimmed | 58,508 | $6M | 0.1% | 2026-Q2 |
| Man Group plc trimmed | 58,295 | $6M | 0.1% | 2026-Q2 |
| POLEN CAPITAL MANAGEMENT LLC added | 55,310 | $6M | 0.1% | 2026-Q2 |
| VANGUARD ASSET MANAGEMENT, Ltd added | 54,810 | $6M | 0.1% | 2026-Q2 |
| Susquehanna Portfolio Strategies, LLC new | 54,617 | $6M | 0.1% | 2026-Q2 |
| ExodusPoint Capital Management, LP trimmed | 51,999 | $5M | 0.1% | 2026-Q2 |
| FRANKLIN RESOURCES INC trimmed | 51,436 | $5M | 0.1% | 2026-Q2 |
| IEQ CAPITAL, LLC trimmed | 51,109 | $5M | 0.1% | 2026-Q2 |
| Jupiter Topco LLC new | 50,539 | $5M | 0.1% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.