Who owns Taysha Gene Therapies (TSHA)
Which tracked institutional funds hold TSHA, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See TSHA company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on TSHA is one-sided between 2026-Q1 and 2026-Q2: 98 added or opened and 11 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
TSHA’s largest tracked holder by dollar value, Avoro Capital Advisors LLC, sizes it at 1.5% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 1.5pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in TSHA divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 202 tracked filers holding TSHA, 137 increased or opened the position and 66 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in TSHA between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 21
- MPM BIOIMPACT LLC$31M
- FARALLON CAPITAL MANAGEMENT, L.L.C.$15M
- NORGES BANK$15M
- ORBIMED ADVISORS LLC$14M
- HEIGHTS CAPITAL MANAGEMENT, INC$10M
- FIRST TRUST ADVISORS LP$5M
Full exits 6
- DEERFIELD MANAGEMENT COMPANY, L.P.$12M
- SG Americas Securities, LLC$10M
- Point72 Asset Management, L.P.$2M
- RENAISSANCE TECHNOLOGIES LLC$2M
- SUPERSTRING CAPITAL MANAGEMENT LP$1M
- TUDOR INVESTMENT CORP ET AL$642K
Largest adds
- Avoro Capital Advisors LLC$66M
- BlackRock, Inc.$59M
- RA CAPITAL MANAGEMENT, L.P.$55M
- GOLDMAN SACHS GROUP INC$55M
- Vestal Point Capital, LP$52M
- VANGUARD CAPITAL MANAGEMENT LLC$39M
Largest trims
- EverSource Wealth Advisors, LLC$19M
- TWO SIGMA INVESTMENTS, LP$2M
- BARCLAYS PLC$340K
- SUSQUEHANNA INTERNATIONAL GROUP, LLP$335K
- Rafferty Asset Management, LLC$287K
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Avoro Capital Advisors LLC added | 23,888,888 | $163M | 8.0% | 2026-Q2 |
| RA CAPITAL MANAGEMENT, L.P. | 23,555,648 | $160M | 7.9% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 22,713,118 | $155M | 7.6% | 2026-Q2 |
| BlackRock, Inc. added | 20,691,927 | $141M | 6.9% | 2026-Q2 |
| Vestal Point Capital, LP added | 19,415,000 | $132M | 6.5% | 2026-Q2 |
| MORGAN STANLEY trimmed | 16,487,479 | $112M | 5.5% | 2026-Q2 |
| RTW INVESTMENTS, LP trimmed | 13,560,258 | $92M | 4.5% | 2026-Q2 |
| FMR LLC trimmed | 13,336,413 | $91M | 4.5% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 12,478,595 | $85M | 4.2% | 2026-Q2 |
| STATE STREET CORP added | 11,421,920 | $78M | 3.8% | 2026-Q2 |
| Siren, L.L.C. added | 9,846,579 | $67M | 3.3% | 2026-Q2 |
| Octagon Capital Advisors LP added | 9,693,244 | $66M | 3.2% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 6,560,394 | $45M | 2.2% | 2026-Q2 |
| Polar Capital Holdings Plc trimmed | 5,117,133 | $35M | 1.7% | 2026-Q2 |
| MPM BIOIMPACT LLC added | 4,500,000 | $31M | 1.5% | 2026-Q2 |
| D. E. Shaw & Co., Inc. trimmed | 4,398,652 | $30M | 1.5% | 2026-Q2 |
| BAKER BROS. ADVISORS LP | 4,004,756 | $27M | 1.3% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP added | 3,975,605 | $27M | 1.3% | 2026-Q2 |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND added | 3,885,501 | $26M | 1.3% | 2026-Q2 |
| Casdin Capital, LLC | 3,250,000 | $22M | 1.1% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 3,140,009 | $21M | 1.0% | 2026-Q2 |
| ADAR1 Capital Management, LLC added | 3,040,466 | $21M | 1.0% | 2026-Q2 |
| Pictet Asset Management Holding SA added | 2,770,701 | $19M | 0.9% | 2026-Q2 |
| Aberdeen Group plc added | 2,327,152 | $16M | 0.8% | 2026-Q2 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. new | 2,250,000 | $15M | 0.8% | 2026-Q2 |
| NORGES BANK added | 2,233,600 | $15M | 0.7% | 2026-Q2 |
| NORTHERN TRUST CORP added | 2,226,210 | $15M | 0.7% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 2,200,695 | $15M | 0.7% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 2,126,838 | $14M | 0.7% | 2026-Q2 |
| ORBIMED ADVISORS LLC new | 2,000,000 | $14M | 0.7% | 2026-Q2 |
| RICE HALL JAMES & ASSOCIATES, LLC added | 1,992,229 | $14M | 0.7% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 1,896,474 | $13M | 0.6% | 2026-Q2 |
| B Group, Inc. | 1,800,556 | $12M | 0.6% | 2026-Q2 |
| Affinity Asset Advisors, LLC added | 1,750,000 | $12M | 0.6% | 2026-Q2 |
| BARCLAYS PLC trimmed | 1,630,659 | $11M | 0.5% | 2026-Q2 |
| CITADEL ADVISORS LLC added | 1,535,287 | $10M | 0.5% | 2026-Q2 |
| Seven Fleet Capital Management LP added | 1,504,400 | $10M | 0.5% | 2026-Q2 |
| HEIGHTS CAPITAL MANAGEMENT, INC new | 1,500,000 | $10M | 0.5% | 2026-Q2 |
| Palo Alto Investors LP | 1,391,382 | $9M | 0.5% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ trimmed | 1,372,845 | $9M | 0.5% | 2026-Q2 |
| Granahan Investment Management, LLC added | 1,305,177 | $9M | 0.4% | 2026-Q2 |
| Quantum Private Wealth, LLC trimmed | 812,027 | $6M | 0.3% | 2026-Q2 |
| FIRST TRUST ADVISORS LP new | 791,169 | $5M | 0.3% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 766,282 | $5M | 0.3% | 2026-Q2 |
| Sands Capital Alternatives, LLC | 724,873 | $5M | 0.2% | 2026-Q2 |
| GordonMD Global Investments LP trimmed | 723,185 | $25M | 1.2% | 2026-Q2 |
| Bank of New York Mellon Corp added | 697,971 | $5M | 0.2% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS added | 640,035 | $4M | 0.2% | 2026-Q2 |
| PANAGORA ASSET MANAGEMENT INC added | 590,387 | $4M | 0.2% | 2026-Q2 |
| UBS Group AG added | 588,427 | $4M | 0.2% | 2026-Q2 |
| AFFINITY WEALTH MANAGEMENT LLC new | 576,808 | $4M | 0.2% | 2026-Q2 |
| Squarepoint Ops LLC added | 569,269 | $4M | 0.2% | 2026-Q2 |
| ACUTA CAPITAL PARTNERS, LLC added | 561,808 | $4M | 0.2% | 2026-Q2 |
| Nuveen, LLC added | 555,693 | $4M | 0.2% | 2026-Q2 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 553,000 | $4M | 0.2% | 2026-Q2 |
| DIADEMA PARTNERS LP new | 522,619 | $4M | 0.2% | 2026-Q2 |
| Hennion & Walsh Asset Management, Inc. added | 519,120 | $4M | 0.2% | 2026-Q2 |
| Woodline Partners LP | 513,828 | $3M | 0.2% | 2026-Q2 |
| Holocene Advisors, LP new | 510,000 | $3M | 0.2% | 2026-Q2 |
| Ghisallo Capital Management LLC new | 505,000 | $3M | 0.2% | 2026-Q2 |
| Burkehill Global Management, LP new | 500,000 | $3M | 0.2% | 2026-Q2 |
| POLEN CAPITAL MANAGEMENT LLC added | 489,219 | $3M | 0.2% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP trimmed | 464,771 | $3M | 0.2% | 2026-Q2 |
| VOYA INVESTMENT MANAGEMENT LLC trimmed | 425,363 | $3M | 0.1% | 2026-Q2 |
| Trexquant Investment LP new | 379,577 | $3M | 0.1% | 2026-Q2 |
| Swiss National Bank added | 369,000 | $3M | 0.1% | 2026-Q2 |
| MOORE CAPITAL MANAGEMENT, LP added | 358,374 | $2M | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 333,314 | $2M | 0.1% | 2026-Q2 |
| Jefferies Financial Group Inc. trimmed | 328,800 | $2M | 0.1% | 2026-Q2 |
| CITIGROUP INC added | 306,907 | $2M | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 299,975 | $2M | 0.1% | 2026-Q2 |
| ALPS ADVISORS INC added | 290,543 | $2M | 0.1% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 272,600 | $2M | 0.1% | 2026-Q2 |
| Invesco Ltd. trimmed | 264,379 | $2M | 0.1% | 2026-Q2 |
| Ensign Peak Advisors, Inc trimmed | 262,896 | $2M | 0.1% | 2026-Q2 |
| Qube Research & Technologies Ltd trimmed | 259,605 | $2M | 0.1% | 2026-Q2 |
| SPHERA FUNDS MANAGEMENT LTD. trimmed | 250,000 | $2M | 0.1% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. added | 247,680 | $1M | 0.1% | 2026-Q2 |
| DEUTSCHE BANK AG\ added | 243,379 | $2M | 0.1% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP trimmed | 234,716 | $2M | 0.1% | 2026-Q2 |
| JANE STREET GROUP, LLC added | 228,355 | $2M | 0.1% | 2026-Q2 |
| Chicago Partners Investment Group LLC added | 222,347 | $1M | 0.1% | 2026-Q2 |
| Monashee Investment Management LLC new | 200,000 | $1M | 0.1% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 199,494 | $1M | 0.1% | 2026-Q2 |
| Privium Fund Management B.V. added | 198,900 | $1M | 0.1% | 2026-Q2 |
| VICTORY CAPITAL MANAGEMENT INC added | 197,578 | $1M | 0.1% | 2026-Q2 |
| BALYASNY ASSET MANAGEMENT L.P. added | 189,332 | $1M | 0.1% | 2026-Q2 |
| STATE OF WISCONSIN INVESTMENT BOARD trimmed | 177,089 | $1M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 169,374 | $1M | 0.1% | 2026-Q2 |
| RAYMOND JAMES FINANCIAL INC added | 166,042 | $1M | 0.1% | 2026-Q2 |
| WEXFORD CAPITAL LP | 160,654 | $1M | 0.1% | 2026-Q2 |
| Rafferty Asset Management, LLC trimmed | 154,706 | $1M | 0.1% | 2026-Q2 |
| Palumbo Wealth Management LLC added | 149,173 | $1M | 0.0% | 2026-Q2 |
| MetLife Investment Management, LLC added | 140,846 | $959K | 0.0% | 2026-Q2 |
| Vanguard Global Advisers, LLC added | 133,821 | $911K | 0.0% | 2026-Q2 |
| Persistent Asset Partners Ltd new | 133,411 | $909K | 0.0% | 2026-Q2 |
| VANGUARD ASSET MANAGEMENT, Ltd added | 132,614 | $903K | 0.0% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 128,764 | $877K | 0.0% | 2026-Q2 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 127,915 | $870K | 0.0% | 2026-Q2 |
| Mariner, LLC added | 116,582 | $794K | 0.0% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.