Who owns Stoke Therapeutics, Inc. (STOK)
Which tracked institutional funds hold STOK, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See STOK company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
60 tracked funds added or opened STOK while 33 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
STOK’s largest tracked holder by dollar value, RTW INVESTMENTS, LP, sizes it at 1.8% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 1.8pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in STOK divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 197 tracked filers holding STOK, 122 increased or opened the position and 83 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in STOK between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 20
- VANGUARD CAPITAL MANAGEMENT LLC$77M
- Troluce Capital Advisors LLC$21M
- MILLENNIUM MANAGEMENT LLC$15M
- VANGUARD PORTFOLIO MANAGEMENT LLC$15M
- VANGUARD FIDUCIARY TRUST CO$12M
- Artisan Partners Limited Partnership$10M
Full exits 8
- VANGUARD GROUP INC$87M
- Point72 Asset Management, L.P.$39M
- Penserra Capital Management LLC$3M
- Alyeska Investment Group, L.P.$2M
- Kennondale Capital Management LLC$1M
- READYSTATE ASSET MANAGEMENT LP$922K
Largest adds
- WELLINGTON MANAGEMENT GROUP LLP$76M
- PRICE T ROWE ASSOCIATES INC /MD/$51M
- BANK OF AMERICA CORP /DE/$11M
- BVF INC/IL$11M
- BAILLIE GIFFORD & CO$11M
- BlackRock, Inc.$10M
Largest trims
- JANUS HENDERSON GROUP PLC$45M
- Lynx1 Capital Management LP$16M
- Assenagon Asset Management S.A.$9M
- GOLDMAN SACHS GROUP INC$9M
- Siren, L.L.C.$6M
- FMR LLC$5M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| RTW INVESTMENTS, LP added | 5,623,525 | $183M | 7.5% | 2026-Q1 |
| BlackRock, Inc. added | 5,385,714 | $175M | 7.2% | 2026-Q1 |
| FMR LLC trimmed | 5,298,109 | $173M | 7.0% | 2026-Q1 |
| Lynx1 Capital Management LP trimmed | 4,763,673 | $155M | 6.3% | 2026-Q1 |
| Redmile Group, LLC added | 4,164,120 | $136M | 5.5% | 2026-Q1 |
| MORGAN STANLEY trimmed | 3,423,280 | $111M | 4.6% | 2026-Q1 |
| BAKER BROS. ADVISORS LP | 3,336,697 | $109M | 4.4% | 2026-Q1 |
| TORONTO DOMINION BANK | 3,173,258 | $103M | 4.2% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP added | 3,048,046 | $99M | 4.1% | 2026-Q1 |
| BVF INC/IL added | 2,547,557 | $83M | 3.4% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 2,355,603 | $77M | 3.1% | 2026-Q1 |
| STATE STREET CORP trimmed | 2,276,512 | $74M | 3.0% | 2026-Q1 |
| Siren, L.L.C. trimmed | 1,995,347 | $65M | 2.7% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 1,934,171 | $63M | 2.6% | 2026-Q1 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,823,500 | $59M | 2.4% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,322,260 | $43M | 1.8% | 2026-Q1 |
| Polar Capital Holdings Plc trimmed | 1,132,511 | $37M | 1.5% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 989,936 | $32M | 1.3% | 2026-Q1 |
| Assenagon Asset Management S.A. trimmed | 907,015 | $30M | 1.2% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC trimmed | 830,702 | $27M | 1.1% | 2026-Q1 |
| MPM BIOIMPACT LLC trimmed | 767,038 | $25M | 1.0% | 2026-Q1 |
| Opaleye Management Inc. added | 700,000 | $23M | 0.9% | 2026-Q1 |
| Troluce Capital Advisors LLC new | 652,800 | $21M | 0.9% | 2026-Q1 |
| BAILLIE GIFFORD & CO added | 575,182 | $19M | 0.8% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 543,095 | $18M | 0.7% | 2026-Q1 |
| Candriam S.C.A. added | 502,020 | $16M | 0.7% | 2026-Q1 |
| TANG CAPITAL MANAGEMENT LLC | 500,000 | $16M | 0.7% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 472,141 | $15M | 0.6% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 462,682 | $15M | 0.6% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 437,175 | $14M | 0.6% | 2026-Q1 |
| Erste Asset Management GmbH added | 446,000 | $14M | 0.6% | 2026-Q1 |
| NORTHERN TRUST CORP added | 431,630 | $14M | 0.6% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 356,947 | $12M | 0.5% | 2026-Q1 |
| Parkman Healthcare Partners LLC trimmed | 336,519 | $11M | 0.4% | 2026-Q1 |
| Granahan Investment Management, LLC added | 335,586 | $11M | 0.4% | 2026-Q1 |
| Artisan Partners Limited Partnership new | 315,492 | $10M | 0.4% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 265,473 | $8M | 0.3% | 2026-Q1 |
| T. Rowe Price Investment Management, Inc. new | 250,913 | $8M | 0.3% | 2026-Q1 |
| Birchview Capital, LP trimmed | 210,000 | $7M | 0.3% | 2026-Q1 |
| FIRST TRUST ADVISORS LP added | 163,459 | $5M | 0.2% | 2026-Q1 |
| UBS Group AG trimmed | 158,304 | $5M | 0.2% | 2026-Q1 |
| Invesco Ltd. trimmed | 150,045 | $5M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp added | 143,407 | $5M | 0.2% | 2026-Q1 |
| FRANKLIN RESOURCES INC added | 142,793 | $5M | 0.2% | 2026-Q1 |
| DAFNA Capital Management LLC added | 130,875 | $4M | 0.2% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 123,022 | $4M | 0.2% | 2026-Q1 |
| Susquehanna Portfolio Strategies, LLC trimmed | 119,226 | $4M | 0.2% | 2026-Q1 |
| GILDER GAGNON HOWE & CO LLC trimmed | 112,627 | $4M | 0.1% | 2026-Q1 |
| Nuveen, LLC added | 108,617 | $4M | 0.1% | 2026-Q1 |
| EcoR1 Capital, LLC new | 100,000 | $3M | 0.1% | 2026-Q1 |
| Palo Alto Investors LP added | 84,631 | $3M | 0.1% | 2026-Q1 |
| HUSSMAN STRATEGIC ADVISORS, INC. added | 84,000 | $3M | 0.1% | 2026-Q1 |
| Rhenman & Partners Asset Management AB trimmed | 83,000 | $3M | 0.1% | 2026-Q1 |
| Swiss National Bank added | 79,100 | $3M | 0.1% | 2026-Q1 |
| Quantedge Capital Pte Ltd trimmed | 78,600 | $3M | 0.1% | 2026-Q1 |
| TD Asset Management Inc added | 74,400 | $2M | 0.1% | 2026-Q1 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE added | 69,222 | $2M | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS added | 67,315 | $2M | 0.1% | 2026-Q1 |
| JANE STREET GROUP, LLC trimmed | 64,349 | $2M | 0.1% | 2026-Q1 |
| PRINCIPAL FINANCIAL GROUP INC trimmed | 63,933 | $2M | 0.1% | 2026-Q1 |
| Harvest Investment Services, LLC added | 62,838 | $2M | 0.1% | 2026-Q1 |
| HighVista Strategies LLC trimmed | 62,617 | $2M | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC trimmed | 59,898 | $2M | 0.1% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 58,185 | $2M | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 57,291 | $2M | 0.1% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 56,128 | $2M | 0.1% | 2026-Q1 |
| Informed Momentum Co LLC trimmed | 52,000 | $2M | 0.1% | 2026-Q1 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 51,606 | $2M | 0.1% | 2026-Q1 |
| Woodline Partners LP | 50,120 | $2M | 0.1% | 2026-Q1 |
| Privium Fund Management B.V. trimmed | 50,000 | $2M | 0.1% | 2026-Q1 |
| D. E. Shaw & Co., Inc. added | 49,972 | $2M | 0.1% | 2026-Q1 |
| Schonfeld Strategic Advisors LLC trimmed | 49,302 | $2M | 0.1% | 2026-Q1 |
| Creative Planning added | 48,108 | $2M | 0.1% | 2026-Q1 |
| STATE OF WISCONSIN INVESTMENT BOARD added | 47,859 | $2M | 0.1% | 2026-Q1 |
| BOOTHBAY FUND MANAGEMENT, LLC added | 47,307 | $2M | 0.1% | 2026-Q1 |
| ALPS ADVISORS INC trimmed | 46,498 | $2M | 0.1% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC added | 46,143 | $2M | 0.1% | 2026-Q1 |
| OMERS ADMINISTRATION Corp added | 41,500 | $1M | 0.1% | 2026-Q1 |
| PLATINUM INVESTMENT MANAGEMENT LTD | 40,815 | $1M | 0.1% | 2026-Q1 |
| ALLIANCEBERNSTEIN L.P. added | 41,830 | $1M | 0.1% | 2026-Q1 |
| DEUTSCHE BANK AG\ added | 40,596 | $1M | 0.1% | 2026-Q1 |
| Moran Wealth Management, LLC new | 40,552 | $1M | 0.1% | 2026-Q1 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 39,158 | $1M | 0.1% | 2026-Q1 |
| LPL Financial LLC added | 36,047 | $1M | 0.0% | 2026-Q1 |
| Caption Management, LLC new | 35,174 | $1M | 0.0% | 2026-Q1 |
| SG Americas Securities, LLC added | 33,996 | $1M | 0.0% | 2026-Q1 |
| VICTORY CAPITAL MANAGEMENT INC trimmed | 33,890 | $1M | 0.0% | 2026-Q1 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 33,873 | $1M | 0.0% | 2026-Q1 |
| VANGUARD GROUP INC trimmed | 2,739,958 | $87M | 3.6% | 2025-Q4 stale |
| Skorpios Trust trimmed | 2,256,181 | $53M | 2.2% | 2025-Q3 stale |
| Point72 Asset Management, L.P. trimmed | 1,222,213 | $39M | 1.6% | 2025-Q4 stale |
| MARSHALL WACE, LLP trimmed | 768,287 | $18M | 0.7% | 2025-Q3 stale |
| Corient Private Wealth LLC new | 659,834 | $7M | 0.3% | 2025-Q2 stale |
| Checkpoint Capital L.P. trimmed | 212,049 | $5M | 0.2% | 2025-Q3 stale |
| Cormorant Asset Management, LP | 254,161 | $3M | 0.1% | 2025-Q2 stale |
| Penserra Capital Management LLC trimmed | 88,507 | $3M | 0.1% | 2025-Q4 stale |
| Alyeska Investment Group, L.P. new | 75,000 | $2M | 0.1% | 2025-Q4 stale |
| Fort Point Capital Partners LLC trimmed | 75,429 | $2M | 0.1% | 2025-Q3 stale |
| Kennondale Capital Management LLC trimmed | 38,731 | $1M | 0.1% | 2025-Q4 stale |
| RENAISSANCE TECHNOLOGIES LLC added | 178,300 | $1M | 0.0% | 2025-Q1 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.