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Institutional Ownership · SEC Form 13F

Who owns SPTX


Which tracked institutional funds hold SPTX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See SPTX company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

53
Institutional holders
37M
Shares held (tracked funds)

Conviction spread

SPTX’s largest tracked holder by dollar value, ARCH Venture Management, LLC, sizes it at 12.4% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 12.4pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in SPTX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Only one quarter (2026-Q2) of 13F history is available — a quarter-over-quarter accumulation delta needs two.

We do not publish a positioning read for a window we cannot measure honestly. A starting question, not a verdict.

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
ARCH Venture Management, LLC new6,294,951$137M16.8%2026-Q2
GENERAL ATLANTIC, L.P. new6,101,582$133M16.3%2026-Q2
Sofinnova Investments, Inc. new3,564,871$77M9.5%2026-Q2
GOLDMAN SACHS GROUP INC new2,178,642$47M5.8%2026-Q2
TRV GP VI, LLC new2,061,222$45M5.5%2026-Q2
CANADA PENSION PLAN INVESTMENT BOARD new1,975,791$43M5.3%2026-Q2
JPMORGAN CHASE & CO new1,815,845$41M5.0%2026-Q2
Foresite Capital Management VI LLC new1,779,521$39M4.7%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ new1,308,604$28M3.5%2026-Q2
FMR LLC new1,185,100$26M3.2%2026-Q2
Bellevue Group AG new1,100,000$24M2.9%2026-Q2
Siren, L.L.C. new1,095,316$24M2.9%2026-Q2
JENNISON ASSOCIATES LLC new1,079,669$23M2.9%2026-Q2
RA CAPITAL MANAGEMENT, L.P. new700,000$15M1.9%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC new599,217$13M1.6%2026-Q2
Woodline Partners LP new586,345$13M1.6%2026-Q2
PERCEPTIVE ADVISORS LLC new500,000$11M1.3%2026-Q2
BRAIDWELL LP new500,000$11M1.3%2026-Q2
PRINCIPAL FINANCIAL GROUP INC new414,672$9M1.1%2026-Q2
Aberdeen Group plc new310,355$7M0.8%2026-Q2
UBS Group AG new279,184$6M0.7%2026-Q2
BlackRock, Inc. new229,863$5M0.6%2026-Q2
SEVEN GRAND MANAGERS, LLC new225,000$5M0.6%2026-Q2
CITADEL ADVISORS LLC new191,144$4M0.5%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC new175,866$4M0.5%2026-Q2
Pier Capital, LLC new169,985$4M0.5%2026-Q2
AMERIPRISE FINANCIAL INC new131,788$3M0.4%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC new97,693$2M0.3%2026-Q2
VANGUARD FIDUCIARY TRUST CO new87,772$2M0.2%2026-Q2
Pentwater Capital Management LP new83,000$2M0.2%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE new82,565$2M0.2%2026-Q2
Alyeska Investment Group, L.P. new75,000$2M0.2%2026-Q2
STATE STREET CORP new66,650$1M0.2%2026-Q2
ALPS ADVISORS INC new54,328$1M0.1%2026-Q2
TD Asset Management Inc new47,944$1M0.1%2026-Q2
MILLENNIUM MANAGEMENT LLC new45,337$985K0.1%2026-Q2
DAFNA Capital Management LLC new32,400$704K0.1%2026-Q2
NORTHERN TRUST CORP new31,802$691K0.1%2026-Q2
ADAR1 Capital Management, LLC new26,000$565K0.1%2026-Q2
Ghisallo Capital Management LLC new25,000$543K0.1%2026-Q2
Burkehill Global Management, LP new25,000$543K0.1%2026-Q2
Squarepoint Ops LLC new24,753$538K0.1%2026-Q2
MORGAN STANLEY new11,692$254K0.0%2026-Q2
XTX Topco Ltd new10,983$239K0.0%2026-Q2
Zimmer Partners, LP new10,000$217K0.0%2026-Q2
Weiss Asset Management LP new10,000$217K0.0%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC new9,081$197K0.0%2026-Q2
Vanguard Global Advisers, LLC new7,159$155K0.0%2026-Q2
CITIGROUP INC new2,454$53K0.0%2026-Q2
JONES FINANCIAL COMPANIES LLLP new2,256$48K0.0%2026-Q2
ASSETMARK, INC new1,431$31K0.0%2026-Q2
BARCLAYS PLC new837$18K0.0%2026-Q2
Integrated Wealth Concepts LLC new32$6950.0%2026-Q2

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership