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Institutional Ownership · SEC Form 13F

Who owns Syndax Pharmaceuticals, Inc. (SNDX)


Which tracked institutional funds hold SNDX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See SNDX company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

245
Institutional holders
99M
Shares held (tracked funds)

How the tape is positioned

99 tracked funds added or opened SNDX while 42 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

SNDX’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 0.1pp gap the other way — the median holder sizes SNDX more heavily than its largest holder by dollar value does.

Book-share is each fund’s reported value in SNDX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 245 tracked filers holding SNDX, 143 increased or opened the position and 96 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in SNDX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 18

  • VANGUARD CAPITAL MANAGEMENT LLC$89M
  • DEERFIELD MANAGEMENT COMPANY, L.P.$88M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$41M
  • ORBIMED ADVISORS LLC$22M
  • Trails Edge Capital Partners, LP$16M
  • VANGUARD FIDUCIARY TRUST CO$14M

Full exits 12

  • VANGUARD GROUP INC$116M
  • EVENTIDE ASSET MANAGEMENT, LLC$26M
  • TWO SIGMA ADVISERS, LP$13M
  • Jump Financial, LLC$3M
  • Y-Intercept (Hong Kong) Ltd$3M
  • Voss Capital, LP$3M

Largest adds

  • BlackRock, Inc.$20M
  • Kynam Capital Management, LP$19M
  • TWO SIGMA INVESTMENTS, LP$13M
  • UBS Group AG$12M
  • D. E. Shaw & Co., Inc.$12M
  • BNP PARIBAS ASSET MANAGEMENT Holding S.A.$12M

Largest trims

  • Point72 Asset Management, L.P.$56M
  • Qube Research & Technologies Ltd$14M
  • Ensign Peak Advisors, Inc$10M
  • ExodusPoint Capital Management, LP$9M
  • JANE STREET GROUP, LLC$8M
  • Soleus Capital Management, L.P.$7M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
BlackRock, Inc. added8,254,426$193M7.6%2026-Q1
Kynam Capital Management, LP8,050,959$188M7.4%2026-Q1
GOLDMAN SACHS GROUP INC trimmed4,996,787$117M4.6%2026-Q1
STATE STREET CORP trimmed4,430,076$103M4.1%2026-Q1
BANK OF AMERICA CORP /DE/ trimmed4,249,836$99M3.9%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new3,822,579$89M3.5%2026-Q1
DEERFIELD MANAGEMENT COMPANY, L.P. added3,779,900$88M3.5%2026-Q1
Eversept Partners, LP trimmed2,885,622$67M2.6%2026-Q1
KINGDON CAPITAL MANAGEMENT, L.L.C. added2,500,000$58M2.3%2026-Q1
Hood River Capital Management LLC added2,354,285$55M2.2%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added2,157,058$50M2.0%2026-Q1
FRANKLIN RESOURCES INC trimmed2,150,079$50M2.0%2026-Q1
Point72 Asset Management, L.P. trimmed1,985,547$46M1.8%2026-Q1
Elmind Capital, LP1,855,000$43M1.7%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new1,737,141$41M1.6%2026-Q1
BNP PARIBAS ASSET MANAGEMENT Holding S.A. added1,732,541$40M1.6%2026-Q1
Soleus Capital Management, L.P. trimmed1,726,908$40M1.6%2026-Q1
D. E. Shaw & Co., Inc. added1,601,896$37M1.5%2026-Q1
TWO SIGMA INVESTMENTS, LP added1,579,596$37M1.4%2026-Q1
Nuveen, LLC added1,494,645$35M1.4%2026-Q1
MPM BIOIMPACT LLC added1,340,733$31M1.2%2026-Q1
Aisling Capital Management LP1,316,806$31M1.2%2026-Q1
Woodline Partners LP added1,250,760$29M1.1%2026-Q1
STEMPOINT CAPITAL LP trimmed1,215,743$28M1.1%2026-Q1
UBS Group AG added1,153,662$27M1.1%2026-Q1
Catalio Capital Management, LP trimmed1,043,670$24M1.0%2026-Q1
Bank of New York Mellon Corp trimmed1,004,498$23M0.9%2026-Q1
Ensign Peak Advisors, Inc trimmed990,969$23M0.9%2026-Q1
AQR CAPITAL MANAGEMENT LLC added964,472$23M0.9%2026-Q1
ORBIMED ADVISORS LLC trimmed962,300$22M0.9%2026-Q1
ALGERT GLOBAL LLC added928,568$22M0.9%2026-Q1
Candriam S.C.A.925,332$22M0.8%2026-Q1
Parkman Healthcare Partners LLC added901,511$21M0.8%2026-Q1
MORGAN STANLEY trimmed893,933$21M0.8%2026-Q1
SILVERARC CAPITAL MANAGEMENT, LLC added888,987$21M0.8%2026-Q1
Palo Alto Investors LP added864,986$20M0.8%2026-Q1
Prosight Management, LP added770,000$18M0.7%2026-Q1
NORTHERN TRUST CORP added755,719$18M0.7%2026-Q1
SPHERA FUNDS MANAGEMENT LTD. trimmed724,563$17M0.7%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed715,153$17M0.7%2026-Q1
Trails Edge Capital Partners, LP new701,821$16M0.6%2026-Q1
CITADEL ADVISORS LLC added630,942$15M0.6%2026-Q1
VANGUARD FIDUCIARY TRUST CO new600,517$14M0.5%2026-Q1
Apis Capital Advisors, LLC trimmed550,000$13M0.5%2026-Q1
RENAISSANCE TECHNOLOGIES LLC trimmed498,200$12M0.5%2026-Q1
Knott David M Jr added422,000$10M0.4%2026-Q1
Walleye Capital LLC added384,973$9M0.4%2026-Q1
Rhenman & Partners Asset Management AB trimmed379,250$9M0.3%2026-Q1
Integral Health Asset Management, LLC added350,000$8M0.3%2026-Q1
JANE STREET GROUP, LLC trimmed335,531$8M0.3%2026-Q1
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND added331,665$8M0.3%2026-Q1
Granahan Investment Management, LLC trimmed306,321$7M0.3%2026-Q1
Aberdeen Group plc trimmed286,969$7M0.3%2026-Q1
SECTOR GAMMA AS added286,007$7M0.3%2026-Q1
Pale Fire Capital SE284,460$7M0.3%2026-Q1
AMERIPRISE FINANCIAL INC added284,245$7M0.3%2026-Q1
Schonfeld Strategic Advisors LLC added260,626$6M0.2%2026-Q1
ALLIANCEBERNSTEIN L.P. added288,567$6M0.2%2026-Q1
Invesco Ltd. added252,761$6M0.2%2026-Q1
PANAGORA ASSET MANAGEMENT INC added249,407$6M0.2%2026-Q1
JPMORGAN CHASE & CO trimmed258,519$6M0.2%2026-Q1
PFM Health Sciences, LP added245,021$6M0.2%2026-Q1
CANADA PENSION PLAN INVESTMENT BOARD229,600$5M0.2%2026-Q1
SEI INVESTMENTS CO added217,600$5M0.2%2026-Q1
DAFNA Capital Management LLC trimmed217,355$5M0.2%2026-Q1
Hennion & Walsh Asset Management, Inc. added214,807$5M0.2%2026-Q1
Brevan Howard Capital Management LP trimmed204,845$5M0.2%2026-Q1
Pinnacle Financial Partners, Inc. trimmed202,282$5M0.2%2026-Q1
Trexquant Investment LP added201,777$5M0.2%2026-Q1
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group200,000$5M0.2%2026-Q1
MILLENNIUM MANAGEMENT LLC added199,524$5M0.2%2026-Q1
ESSEX INVESTMENT MANAGEMENT CO LLC new198,985$5M0.2%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP added196,621$5M0.2%2026-Q1
Man Group plc added182,016$4M0.2%2026-Q1
Squarepoint Ops LLC added181,552$4M0.2%2026-Q1
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.180,000$4M0.2%2026-Q1
FMR LLC added173,993$4M0.2%2026-Q1
Swiss National Bank161,400$4M0.1%2026-Q1
Atom Investors LP added155,965$4M0.1%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added149,797$3M0.1%2026-Q1
CAPITAL FUND MANAGEMENT S.A. trimmed145,566$3M0.1%2026-Q1
Rafferty Asset Management, LLC trimmed124,723$3M0.1%2026-Q1
VANGUARD GROUP INC added5,527,345$116M4.6%2025-Q4 stale
ADAGE CAPITAL PARTNERS GP, L.L.C. added3,311,963$51M2.0%2025-Q3 stale
Octagon Capital Advisors LP added27,330,800$48M1.9%2025-Q1 stale
EVENTIDE ASSET MANAGEMENT, LLC added1,238,196$26M1.0%2025-Q4 stale
THORNBURG INVESTMENT MANAGEMENT INC added130,746$16M0.6%2025-Q1 stale
Sofinnova Investments, Inc. trimmed1,524,440$14M0.6%2025-Q2 stale
TWO SIGMA ADVISERS, LP added632,752$13M0.5%2025-Q4 stale
Nantahala Capital Management, LLC added754,503$7M0.3%2025-Q2 stale
Casdin Capital, LLC added650,000$6M0.2%2025-Q2 stale
Zimmer Partners, LP trimmed383,100$6M0.2%2025-Q3 stale
Ikarian Capital, LLC added333,733$5M0.2%2025-Q3 stale
Caption Management, LLC added504,471$5M0.2%2025-Q2 stale
Saturn V Capital Management LP trimmed500,551$5M0.2%2025-Q2 stale
BOOTHBAY FUND MANAGEMENT, LLC added261,933$4M0.2%2025-Q3 stale
Cubist Systematic Strategies, LLC added246,779$4M0.1%2025-Q3 stale
Jump Financial, LLC added163,915$3M0.1%2025-Q4 stale
Y-Intercept (Hong Kong) Ltd added155,916$3M0.1%2025-Q4 stale
TANG CAPITAL MANAGEMENT LLC200,000$3M0.1%2025-Q3 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership