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Institutional Ownership · SEC Form 13F

Who owns Silence Therapeutics plc (SLN)


Which tracked institutional funds hold SLN, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See SLN company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

56
Institutional holders
20M
Shares held (tracked funds)
14.0%
Of shares outstanding

How the tape is positioned

13 tracked funds added or opened SLN while 11 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

SLN’s largest tracked holder by dollar value, TCG Crossover Management, LLC, sizes it at 0.5% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.5pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in SLN divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 56 tracked filers holding SLN, 30 increased or opened the position and 19 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in SLN between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 1

  • Jones Hill Capital LP$2M

Full exits 2

  • Vivo Capital, LLC$7M
  • Lombard Odier Asset Management (USA) Corp$1M

Largest adds

  • CITADEL ADVISORS LLC$5M
  • Nantahala Capital Management, LLC$2M
  • MILLENNIUM MANAGEMENT LLC$2M
  • Tetragon Partners GP Ltd$1M
  • ADAR1 Capital Management, LLC$764K
  • BNP PARIBAS FINANCIAL MARKETS$705K

Largest trims

  • TCG Crossover Management, LLC$2M
  • Siren, L.L.C.$2M
  • Redmile Group, LLC$2M
  • MORGAN STANLEY$2M
  • Nextech Invest, Ltd.$771K
  • Ishara Investments LP$719K

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
TCG Crossover Management, LLC3,033,560$16M13.0%2026-Q1
Siren, L.L.C.2,911,438$15M12.4%2026-Q1
Redmile Group, LLC2,164,777$11M9.3%2026-Q1
Nantahala Capital Management, LLC added2,146,731$11M9.2%2026-Q1
CITADEL ADVISORS LLC added1,234,807$7M5.3%2026-Q1
MILLENNIUM MANAGEMENT LLC added1,074,191$6M4.6%2026-Q1
GREAT POINT PARTNERS LLC added1,020,489$5M4.4%2026-Q1
Nextech Invest, Ltd.952,400$5M4.1%2026-Q1
Tetragon Partners GP Ltd added630,161$3M2.7%2026-Q1
5AM Venture Management, LLC476,200$3M2.0%2026-Q1
Ikarian Capital, LLC865,784$2M1.4%2026-Q1
Jones Hill Capital LP new301,604$2M1.3%2026-Q1
SG Americas Securities, LLC added286,698$2M1.2%2026-Q1
UBS Group AG added246,937$1M1.1%2026-Q1
BOOTHBAY FUND MANAGEMENT, LLC209,088$1M0.9%2026-Q1
BlackRock, Inc. added204,777$1M0.9%2026-Q1
BANK OF MONTREAL /CAN/ added202,901$1M0.9%2026-Q1
ADAR1 Capital Management, LLC added172,157$907K0.7%2026-Q1
MARSHALL WACE, LLP added167,931$885K0.7%2026-Q1
Seven Fleet Capital Management LP added156,759$826K0.7%2026-Q1
BNP PARIBAS FINANCIAL MARKETS added147,668$778K0.6%2026-Q1
Ishara Investments LP trimmed140,500$740K0.6%2026-Q1
HSBC HOLDINGS PLC trimmed122,834$640K0.5%2026-Q1
Point72 Asset Management, L.P. added119,711$631K0.5%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP added115,281$608K0.5%2026-Q1
XTX Topco Ltd added106,002$559K0.5%2026-Q1
Qube Research & Technologies Ltd added104,555$551K0.4%2026-Q1
M28 Capital Management LP trimmed101,203$533K0.4%2026-Q1
JANE STREET GROUP, LLC added100,927$532K0.4%2026-Q1
Squarepoint Ops LLC new89,469$472K0.4%2026-Q1
MORGAN STANLEY trimmed65,486$345K0.3%2026-Q1
GOLDMAN SACHS GROUP INC added52,511$277K0.2%2026-Q1
BANK OF AMERICA CORP /DE/ added29,773$157K0.1%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC29,538$156K0.1%2026-Q1
RAYMOND JAMES FINANCIAL INC25,000$132K0.1%2026-Q1
TWO SIGMA INVESTMENTS, LP trimmed16,203$85K0.1%2026-Q1
RHUMBLINE ADVISERS added13,935$73K0.1%2026-Q1
HRT FINANCIAL LP added11,994$63K0.1%2026-Q1
Dynamic Technology Lab Private Ltd new10,490$55K0.0%2026-Q1
GAMMA Investing LLC trimmed9,365$49K0.0%2026-Q1
China Universal Asset Management Co., Ltd. trimmed8,335$44K0.0%2026-Q1
JPMORGAN CHASE & CO trimmed7,636$38K0.0%2026-Q1
ACADIAN ASSET MANAGEMENT LLC added4,818$25K0.0%2026-Q1
BARCLAYS PLC trimmed2,937$15K0.0%2026-Q1
Mirae Asset Global Investments Co., Ltd. added2,450$13K0.0%2026-Q1
JONES FINANCIAL COMPANIES LLLP2,500$12K0.0%2026-Q1
Tower Research Capital LLC (TRC) trimmed2,313$12K0.0%2026-Q1
CITIGROUP INC added1,835$10K0.0%2026-Q1
Parallel Advisors, LLC1,300$7K0.0%2026-Q1
GF FUND MANAGEMENT CO. LTD. added1,047$6K0.0%2026-Q1
SIMPLEX TRADING, LLC trimmed612$3K0.0%2026-Q1
Steward Partners Investment Advisory, LLC100$5270.0%2026-Q1
Rockefeller Capital Management L.P.45$2370.0%2026-Q1
SBI Securities Co., Ltd.28$1480.0%2026-Q1
Caitong International Asset Management Co., Ltd new3$160.0%2026-Q1
ROYAL BANK OF CANADA160.0%2026-Q1
Vivo Capital, LLC1,105,454$7M5.5%2025-Q4 stale
Frazier Life Sciences Management, L.P.970,130$5M4.1%2025-Q3 stale
CANTOR FITZGERALD, L. P. added801,306$4M3.4%2025-Q3 stale
Lombard Odier Asset Management (USA) Corp trimmed255,901$1M0.9%2025-Q4 stale
Parkman Healthcare Partners LLC trimmed401,746$1M0.9%2025-Q1 stale
Opaleye Management Inc. new78,926$480K0.4%2025-Q4 stale
Schonfeld Strategic Advisors LLC added149,996$423K0.3%2025-Q1 stale
Walleye Capital LLC added136,150$384K0.3%2025-Q1 stale
Quadrature Capital Ltd new54,380$331K0.3%2025-Q4 stale
Woodline Partners LP62,459$324K0.3%2025-Q3 stale
Saturn V Capital Management LP trimmed34,737$201K0.2%2025-Q2 stale
Shay Capital LLC added47,728$135K0.1%2025-Q1 stale
Massar Capital Management, LP new19,863$115K0.1%2025-Q2 stale
Rathbones Group PLC18,421$107K0.1%2025-Q2 stale
Virtus Investment Advisers, LLC added20,374$106K0.1%2025-Q3 stale
TWO SIGMA ADVISERS, LP trimmed15,900$97K0.1%2025-Q4 stale
Jump Financial, LLC added26,351$74K0.1%2025-Q1 stale
Beacon Pointe Advisors, LLC new11,615$67K0.1%2025-Q2 stale
EHP Funds Inc. new10,673$55K0.0%2025-Q3 stale
Cambridge Investment Research Advisors, Inc.10,194$53K0.0%2025-Q3 stale
WEXFORD CAPITAL LP trimmed7,708$40K0.0%2025-Q3 stale
Cubist Systematic Strategies, LLC trimmed7,364$21K0.0%2025-Q1 stale
FNY Investment Advisers, LLC trimmed7,000$19K0.0%2025-Q1 stale
Global Retirement Partners, LLC new1,000$6K0.0%2025-Q4 stale
PRINCIPAL SECURITIES, INC.17$880.0%2025-Q3 stale
SageView Advisory Group, LLC new11$670.0%2025-Q4 stale
EverSource Wealth Advisors, LLC new10$580.0%2025-Q2 stale
OSAIC HOLDINGS, INC. trimmed3$180.0%2025-Q4 stale
CONCOURSE FINANCIAL GROUP SECURITIES, INC.00.0%2025-Q2 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership