Who owns Silence Therapeutics plc (SLN)
Which tracked institutional funds hold SLN, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See SLN company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
13 tracked funds added or opened SLN while 11 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
SLN’s largest tracked holder by dollar value, TCG Crossover Management, LLC, sizes it at 0.5% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.5pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in SLN divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 56 tracked filers holding SLN, 30 increased or opened the position and 19 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in SLN between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 1
- Jones Hill Capital LP$2M
Full exits 2
- Vivo Capital, LLC$7M
- Lombard Odier Asset Management (USA) Corp$1M
Largest adds
- CITADEL ADVISORS LLC$5M
- Nantahala Capital Management, LLC$2M
- MILLENNIUM MANAGEMENT LLC$2M
- Tetragon Partners GP Ltd$1M
- ADAR1 Capital Management, LLC$764K
- BNP PARIBAS FINANCIAL MARKETS$705K
Largest trims
- TCG Crossover Management, LLC$2M
- Siren, L.L.C.$2M
- Redmile Group, LLC$2M
- MORGAN STANLEY$2M
- Nextech Invest, Ltd.$771K
- Ishara Investments LP$719K
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| TCG Crossover Management, LLC | 3,033,560 | $16M | 13.0% | 2026-Q1 |
| Siren, L.L.C. | 2,911,438 | $15M | 12.4% | 2026-Q1 |
| Redmile Group, LLC | 2,164,777 | $11M | 9.3% | 2026-Q1 |
| Nantahala Capital Management, LLC added | 2,146,731 | $11M | 9.2% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 1,234,807 | $7M | 5.3% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 1,074,191 | $6M | 4.6% | 2026-Q1 |
| GREAT POINT PARTNERS LLC added | 1,020,489 | $5M | 4.4% | 2026-Q1 |
| Nextech Invest, Ltd. | 952,400 | $5M | 4.1% | 2026-Q1 |
| Tetragon Partners GP Ltd added | 630,161 | $3M | 2.7% | 2026-Q1 |
| 5AM Venture Management, LLC | 476,200 | $3M | 2.0% | 2026-Q1 |
| Ikarian Capital, LLC | 865,784 | $2M | 1.4% | 2026-Q1 |
| Jones Hill Capital LP new | 301,604 | $2M | 1.3% | 2026-Q1 |
| SG Americas Securities, LLC added | 286,698 | $2M | 1.2% | 2026-Q1 |
| UBS Group AG added | 246,937 | $1M | 1.1% | 2026-Q1 |
| BOOTHBAY FUND MANAGEMENT, LLC | 209,088 | $1M | 0.9% | 2026-Q1 |
| BlackRock, Inc. added | 204,777 | $1M | 0.9% | 2026-Q1 |
| BANK OF MONTREAL /CAN/ added | 202,901 | $1M | 0.9% | 2026-Q1 |
| ADAR1 Capital Management, LLC added | 172,157 | $907K | 0.7% | 2026-Q1 |
| MARSHALL WACE, LLP added | 167,931 | $885K | 0.7% | 2026-Q1 |
| Seven Fleet Capital Management LP added | 156,759 | $826K | 0.7% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 147,668 | $778K | 0.6% | 2026-Q1 |
| Ishara Investments LP trimmed | 140,500 | $740K | 0.6% | 2026-Q1 |
| HSBC HOLDINGS PLC trimmed | 122,834 | $640K | 0.5% | 2026-Q1 |
| Point72 Asset Management, L.P. added | 119,711 | $631K | 0.5% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 115,281 | $608K | 0.5% | 2026-Q1 |
| XTX Topco Ltd added | 106,002 | $559K | 0.5% | 2026-Q1 |
| Qube Research & Technologies Ltd added | 104,555 | $551K | 0.4% | 2026-Q1 |
| M28 Capital Management LP trimmed | 101,203 | $533K | 0.4% | 2026-Q1 |
| JANE STREET GROUP, LLC added | 100,927 | $532K | 0.4% | 2026-Q1 |
| Squarepoint Ops LLC new | 89,469 | $472K | 0.4% | 2026-Q1 |
| MORGAN STANLEY trimmed | 65,486 | $345K | 0.3% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 52,511 | $277K | 0.2% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 29,773 | $157K | 0.1% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC | 29,538 | $156K | 0.1% | 2026-Q1 |
| RAYMOND JAMES FINANCIAL INC | 25,000 | $132K | 0.1% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP trimmed | 16,203 | $85K | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS added | 13,935 | $73K | 0.1% | 2026-Q1 |
| HRT FINANCIAL LP added | 11,994 | $63K | 0.1% | 2026-Q1 |
| Dynamic Technology Lab Private Ltd new | 10,490 | $55K | 0.0% | 2026-Q1 |
| GAMMA Investing LLC trimmed | 9,365 | $49K | 0.0% | 2026-Q1 |
| China Universal Asset Management Co., Ltd. trimmed | 8,335 | $44K | 0.0% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 7,636 | $38K | 0.0% | 2026-Q1 |
| ACADIAN ASSET MANAGEMENT LLC added | 4,818 | $25K | 0.0% | 2026-Q1 |
| BARCLAYS PLC trimmed | 2,937 | $15K | 0.0% | 2026-Q1 |
| Mirae Asset Global Investments Co., Ltd. added | 2,450 | $13K | 0.0% | 2026-Q1 |
| JONES FINANCIAL COMPANIES LLLP | 2,500 | $12K | 0.0% | 2026-Q1 |
| Tower Research Capital LLC (TRC) trimmed | 2,313 | $12K | 0.0% | 2026-Q1 |
| CITIGROUP INC added | 1,835 | $10K | 0.0% | 2026-Q1 |
| Parallel Advisors, LLC | 1,300 | $7K | 0.0% | 2026-Q1 |
| GF FUND MANAGEMENT CO. LTD. added | 1,047 | $6K | 0.0% | 2026-Q1 |
| SIMPLEX TRADING, LLC trimmed | 612 | $3K | 0.0% | 2026-Q1 |
| Steward Partners Investment Advisory, LLC | 100 | $527 | 0.0% | 2026-Q1 |
| Rockefeller Capital Management L.P. | 45 | $237 | 0.0% | 2026-Q1 |
| SBI Securities Co., Ltd. | 28 | $148 | 0.0% | 2026-Q1 |
| Caitong International Asset Management Co., Ltd new | 3 | $16 | 0.0% | 2026-Q1 |
| ROYAL BANK OF CANADA | 16 | — | 0.0% | 2026-Q1 |
| Vivo Capital, LLC | 1,105,454 | $7M | 5.5% | 2025-Q4 stale |
| Frazier Life Sciences Management, L.P. | 970,130 | $5M | 4.1% | 2025-Q3 stale |
| CANTOR FITZGERALD, L. P. added | 801,306 | $4M | 3.4% | 2025-Q3 stale |
| Lombard Odier Asset Management (USA) Corp trimmed | 255,901 | $1M | 0.9% | 2025-Q4 stale |
| Parkman Healthcare Partners LLC trimmed | 401,746 | $1M | 0.9% | 2025-Q1 stale |
| Opaleye Management Inc. new | 78,926 | $480K | 0.4% | 2025-Q4 stale |
| Schonfeld Strategic Advisors LLC added | 149,996 | $423K | 0.3% | 2025-Q1 stale |
| Walleye Capital LLC added | 136,150 | $384K | 0.3% | 2025-Q1 stale |
| Quadrature Capital Ltd new | 54,380 | $331K | 0.3% | 2025-Q4 stale |
| Woodline Partners LP | 62,459 | $324K | 0.3% | 2025-Q3 stale |
| Saturn V Capital Management LP trimmed | 34,737 | $201K | 0.2% | 2025-Q2 stale |
| Shay Capital LLC added | 47,728 | $135K | 0.1% | 2025-Q1 stale |
| Massar Capital Management, LP new | 19,863 | $115K | 0.1% | 2025-Q2 stale |
| Rathbones Group PLC | 18,421 | $107K | 0.1% | 2025-Q2 stale |
| Virtus Investment Advisers, LLC added | 20,374 | $106K | 0.1% | 2025-Q3 stale |
| TWO SIGMA ADVISERS, LP trimmed | 15,900 | $97K | 0.1% | 2025-Q4 stale |
| Jump Financial, LLC added | 26,351 | $74K | 0.1% | 2025-Q1 stale |
| Beacon Pointe Advisors, LLC new | 11,615 | $67K | 0.1% | 2025-Q2 stale |
| EHP Funds Inc. new | 10,673 | $55K | 0.0% | 2025-Q3 stale |
| Cambridge Investment Research Advisors, Inc. | 10,194 | $53K | 0.0% | 2025-Q3 stale |
| WEXFORD CAPITAL LP trimmed | 7,708 | $40K | 0.0% | 2025-Q3 stale |
| Cubist Systematic Strategies, LLC trimmed | 7,364 | $21K | 0.0% | 2025-Q1 stale |
| FNY Investment Advisers, LLC trimmed | 7,000 | $19K | 0.0% | 2025-Q1 stale |
| Global Retirement Partners, LLC new | 1,000 | $6K | 0.0% | 2025-Q4 stale |
| PRINCIPAL SECURITIES, INC. | 17 | $88 | 0.0% | 2025-Q3 stale |
| SageView Advisory Group, LLC new | 11 | $67 | 0.0% | 2025-Q4 stale |
| EverSource Wealth Advisors, LLC new | 10 | $58 | 0.0% | 2025-Q2 stale |
| OSAIC HOLDINGS, INC. trimmed | 3 | $18 | 0.0% | 2025-Q4 stale |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | — | 0.0% | 2025-Q2 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.