Who owns Silence Therapeutics (SLN)
Which tracked institutional funds hold SLN, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See SLN company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-02). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on SLN is one-sided between 2026-Q1 and 2026-Q2: 36 added or opened and 4 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
SLN’s largest tracked holder by dollar value, Siren, L.L.C., sizes it at 0.7% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.7pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in SLN divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 68 tracked filers holding SLN, 38 increased or opened the position and 25 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in SLN between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 10
- Soleus Capital Management, L.P.$7M
- BALYASNY ASSET MANAGEMENT L.P.$7M
- AMERIPRISE FINANCIAL INC$4M
- SummitTX Capital, L.P.$4M
- Schonfeld Strategic Advisors LLC$3M
- Propel Bio Management, LLC$2M
Full exits 3
- Jones Hill Capital LP$2M
- SG Americas Securities, LLC$2M
- Point72 Asset Management, L.P.$631K
Largest adds
- Siren, L.L.C.$21M
- TCG Crossover Management, LLC$17M
- Redmile Group, LLC$12M
- CITADEL ADVISORS LLC$8M
- Nextech Invest Ltd.$5M
- Tetragon Partners GP Ltd$5M
Largest trims
- GREAT POINT PARTNERS LLC$437K
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Siren, L.L.C. added | 3,311,438 | $36M | 14.0% | 2026-Q2 |
| TCG Crossover Management, LLC | 3,033,560 | $33M | 12.8% | 2026-Q2 |
| Redmile Group, LLC | 2,164,777 | $24M | 9.1% | 2026-Q2 |
| Nantahala Capital Management, LLC trimmed | 1,346,731 | $15M | 5.7% | 2026-Q2 |
| CITADEL ADVISORS LLC added | 1,329,625 | $15M | 5.6% | 2026-Q2 |
| Nextech Invest Ltd. | 952,400 | $10M | 4.0% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 909,279 | $10M | 3.8% | 2026-Q2 |
| Tetragon Partners GP Ltd added | 764,256 | $8M | 3.2% | 2026-Q2 |
| Soleus Capital Management, L.P. added | 630,000 | $7M | 2.7% | 2026-Q2 |
| BALYASNY ASSET MANAGEMENT L.P. new | 610,980 | $7M | 2.6% | 2026-Q2 |
| 5AM Venture Management, LLC | 476,200 | $5M | 2.0% | 2026-Q2 |
| GREAT POINT PARTNERS LLC trimmed | 450,000 | $5M | 1.9% | 2026-Q2 |
| MORGAN STANLEY added | 403,172 | $4M | 1.7% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC added | 370,052 | $4M | 1.6% | 2026-Q2 |
| JANE STREET GROUP, LLC added | 369,151 | $4M | 1.6% | 2026-Q2 |
| ADAR1 Capital Management, LLC added | 338,373 | $4M | 1.4% | 2026-Q2 |
| SummitTX Capital, L.P. new | 326,648 | $4M | 1.4% | 2026-Q2 |
| Schonfeld Strategic Advisors LLC added | 269,348 | $3M | 1.1% | 2026-Q2 |
| UBS Group AG trimmed | 243,152 | $3M | 1.0% | 2026-Q2 |
| Ishara Investments LP trimmed | 55,350 | $2M | 0.9% | 2026-Q2 |
| BlackRock, Inc. added | 219,917 | $2M | 0.9% | 2026-Q2 |
| BANK OF MONTREAL /CAN/ trimmed | 201,734 | $2M | 0.9% | 2026-Q2 |
| BOOTHBAY FUND MANAGEMENT, LLC trimmed | 198,347 | $2M | 0.8% | 2026-Q2 |
| Propel Bio Management, LLC new | 191,733 | $2M | 0.8% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 184,519 | $2M | 0.8% | 2026-Q2 |
| FRED ALGER MANAGEMENT, LLC new | 177,000 | $2M | 0.7% | 2026-Q2 |
| Ikarian Capital, LLC trimmed | 830,784 | $2M | 0.7% | 2026-Q2 |
| Qube Research & Technologies Ltd added | 163,945 | $2M | 0.7% | 2026-Q2 |
| Caption Management, LLC new | 162,476 | $2M | 0.7% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS added | 158,950 | $2M | 0.7% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 155,929 | $2M | 0.7% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP added | 121,004 | $1M | 0.5% | 2026-Q2 |
| HSBC HOLDINGS PLC | 122,834 | $1M | 0.5% | 2026-Q2 |
| Quadrature Capital Ltd added | 118,129 | $1M | 0.5% | 2026-Q2 |
| Squarepoint Ops LLC added | 115,918 | $1M | 0.5% | 2026-Q2 |
| XTX Topco Ltd added | 107,579 | $1M | 0.5% | 2026-Q2 |
| M28 Capital Management LP | 101,203 | $1M | 0.4% | 2026-Q2 |
| MARSHALL WACE, LLP trimmed | 72,039 | $791K | 0.3% | 2026-Q2 |
| Birchview Capital, LP new | 71,218 | $782K | 0.3% | 2026-Q2 |
| Seven Fleet Capital Management LP trimmed | 60,107 | $660K | 0.3% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC | 29,538 | $324K | 0.1% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ trimmed | 25,280 | $278K | 0.1% | 2026-Q2 |
| Trexquant Investment LP trimmed | 23,842 | $262K | 0.1% | 2026-Q2 |
| Verdad Advisers, LP new | 20,400 | $224K | 0.1% | 2026-Q2 |
| Scientech Research LLC new | 19,133 | $210K | 0.1% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC new | 16,930 | $186K | 0.1% | 2026-Q2 |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. new | 16,334 | $179K | 0.1% | 2026-Q2 |
| Persistent Asset Partners Ltd new | 15,170 | $167K | 0.1% | 2026-Q2 |
| RAYMOND JAMES FINANCIAL INC trimmed | 15,000 | $165K | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS trimmed | 13,815 | $152K | 0.1% | 2026-Q2 |
| CITIGROUP INC added | 13,217 | $145K | 0.1% | 2026-Q2 |
| AXQ CAPITAL, LP new | 12,566 | $138K | 0.1% | 2026-Q2 |
| GAMMA Investing LLC added | 11,063 | $121K | 0.0% | 2026-Q2 |
| CenterBook Partners LP new | 10,416 | $114K | 0.0% | 2026-Q2 |
| China Universal Asset Management Co., Ltd. trimmed | 7,475 | $82K | 0.0% | 2026-Q2 |
| JPMORGAN CHASE & CO trimmed | 3,863 | $42K | 0.0% | 2026-Q2 |
| BARCLAYS PLC added | 3,418 | $38K | 0.0% | 2026-Q2 |
| JONES FINANCIAL COMPANIES LLLP | 2,500 | $25K | 0.0% | 2026-Q2 |
| Mirae Asset Global Investments Co., Ltd. trimmed | 2,101 | $23K | 0.0% | 2026-Q2 |
| Tower Research Capital LLC (TRC) trimmed | 1,639 | $18K | 0.0% | 2026-Q2 |
| Parallel Advisors, LLC | 1,300 | $14K | 0.0% | 2026-Q2 |
| Rialto Wealth Management, LLC new | 1,021 | $11K | 0.0% | 2026-Q2 |
| GF FUND MANAGEMENT CO. LTD. trimmed | 975 | $11K | 0.0% | 2026-Q2 |
| Steward Partners Investment Advisory, LLC | 100 | $1K | 0.0% | 2026-Q2 |
| Rockefeller Capital Management L.P. | 45 | $494 | 0.0% | 2026-Q2 |
| Caitong International Asset Management Co., Ltd added | 41 | $450 | 0.0% | 2026-Q2 |
| SBI Securities Co., Ltd. | 28 | $307 | 0.0% | 2026-Q2 |
| ROYAL BANK OF CANADA added | 26 | — | 0.0% | 2026-Q2 |
| Vivo Capital, LLC | 1,105,454 | $7M | 2.6% | 2025-Q4 stale (2 quarters behind) |
| Frazier Life Sciences Management, L.P. | 970,130 | $5M | 1.9% | 2025-Q3 stale (3 quarters behind) |
| CANTOR FITZGERALD, L. P. added | 801,306 | $4M | 1.6% | 2025-Q3 stale (3 quarters behind) |
| Jones Hill Capital LP new | 301,604 | $2M | 0.6% | 2026-Q1 stale (1 quarter behind) |
| SG Americas Securities, LLC added | 286,698 | $2M | 0.6% | 2026-Q1 stale (1 quarter behind) |
| Lombard Odier Asset Management (USA) Corp trimmed | 255,901 | $1M | 0.4% | 2025-Q4 stale (2 quarters behind) |
| Point72 Asset Management, L.P. added | 119,711 | $631K | 0.2% | 2026-Q1 stale (1 quarter behind) |
| Opaleye Management Inc. new | 78,926 | $480K | 0.2% | 2025-Q4 stale (2 quarters behind) |
| Woodline Partners LP | 62,459 | $324K | 0.1% | 2025-Q3 stale (3 quarters behind) |
| Saturn V Capital Management LP trimmed | 34,737 | $201K | 0.1% | 2025-Q2 stale (4 quarters behind) |
| Massar Capital Management, LP new | 19,863 | $115K | 0.0% | 2025-Q2 stale (4 quarters behind) |
| Rathbones Group PLC | 18,421 | $107K | 0.0% | 2025-Q2 stale (4 quarters behind) |
| Virtus Investment Advisers, LLC added | 20,374 | $106K | 0.0% | 2025-Q3 stale (3 quarters behind) |
| TWO SIGMA ADVISERS, LP trimmed | 15,900 | $97K | 0.0% | 2025-Q4 stale (2 quarters behind) |
| Beacon Pointe Advisors, LLC new | 11,615 | $67K | 0.0% | 2025-Q2 stale (4 quarters behind) |
| HRT FINANCIAL LP added | 11,994 | $63K | 0.0% | 2026-Q1 stale (1 quarter behind) |
| EHP Funds Inc. new | 10,673 | $55K | 0.0% | 2025-Q3 stale (3 quarters behind) |
| Dynamic Technology Lab Private Ltd new | 10,490 | $55K | 0.0% | 2026-Q1 stale (1 quarter behind) |
| Cambridge Investment Research Advisors, Inc. | 10,194 | $53K | 0.0% | 2025-Q3 stale (3 quarters behind) |
| WEXFORD CAPITAL LP trimmed | 7,708 | $40K | 0.0% | 2025-Q3 stale (3 quarters behind) |
| ACADIAN ASSET MANAGEMENT LLC added | 4,818 | $25K | 0.0% | 2026-Q1 stale (1 quarter behind) |
| Global Retirement Partners, LLC new | 1,000 | $6K | 0.0% | 2025-Q4 stale (2 quarters behind) |
| SIMPLEX TRADING, LLC trimmed | 612 | $3K | 0.0% | 2026-Q1 stale (1 quarter behind) |
| PRINCIPAL SECURITIES, INC. | 17 | $88 | 0.0% | 2025-Q3 stale (3 quarters behind) |
| SageView Advisory Group, LLC new | 11 | $67 | 0.0% | 2025-Q4 stale (2 quarters behind) |
| EverSource Wealth Advisors, LLC new | 10 | $58 | 0.0% | 2025-Q2 stale (4 quarters behind) |
| OSAIC HOLDINGS, INC. trimmed | 3 | $18 | 0.0% | 2025-Q4 stale (2 quarters behind) |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | — | 0.0% | 2025-Q2 stale (4 quarters behind) |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.