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Institutional Ownership · SEC Form 13F

Who owns SION (SION)


Which tracked institutional funds hold SION, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See SION company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

122
Institutional holders
45,407,335
Shares held (tracked funds)

How the tape is positioned

31 tracked funds added or opened SION while 25 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

SION’s largest tracked holder by dollar value, RA CAPITAL MANAGEMENT, L.P., sizes it at 4.2% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 4.2pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in SION divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 122 tracked filers holding SION, 72 increased or opened the position and 41 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in SION between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 15

  • VANGUARD CAPITAL MANAGEMENT LLC$41M
  • Sio Capital Management, LLC$12M
  • Candriam S.C.A.$9M
  • ADAGE CAPITAL PARTNERS GP, L.L.C.$6M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$6M
  • Point72 Asset Management, L.P.$5M

Full exits 1

  • VANGUARD GROUP INC$44M

Largest adds

  • JENNISON ASSOCIATES LLC$12M
  • GOLDMAN SACHS GROUP INC$9M
  • Ensign Peak Advisors, Inc$7M
  • MORGAN STANLEY$3M
  • FMR LLC$3M
  • JPMORGAN CHASE & CO$3M

Largest trims

  • PERCEPTIVE ADVISORS LLC$22M
  • TPG GP A, LLC$17M
  • Aberdeen Group plc$12M
  • RA CAPITAL MANAGEMENT, L.P.$10M
  • ORBIMED ADVISORS LLC$5M
  • Invesco Ltd.$4M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
RA CAPITAL MANAGEMENT, L.P.9,905,045$397M21.1%2026-Q1
TPG GP A, LLC trimmed6,494,962$260M13.9%2026-Q1
ORBIMED ADVISORS LLC trimmed3,530,702$142M7.5%2026-Q1
VIKING GLOBAL INVESTORS LP3,195,181$128M6.8%2026-Q1
Atlas Venture Life Science Advisors, LLC2,995,602$120M6.4%2026-Q1
ENAVATE SCIENCES GP, LLC2,478,030$99M5.3%2026-Q1
JENNISON ASSOCIATES LLC added1,451,220$58M3.1%2026-Q1
JPMORGAN CHASE & CO added1,465,014$54M2.9%2026-Q1
BlackRock, Inc. added1,295,867$52M2.8%2026-Q1
CITADEL ADVISORS LLC added1,166,931$47M2.5%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new1,029,497$41M2.2%2026-Q1
DEERFIELD MANAGEMENT COMPANY, L.P.970,590$39M2.1%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ trimmed756,376$30M1.6%2026-Q1
STATE STREET CORP added756,227$30M1.6%2026-Q1
PERCEPTIVE ADVISORS LLC trimmed658,439$26M1.4%2026-Q1
EVENTIDE ASSET MANAGEMENT, LLC added645,530$26M1.4%2026-Q1
Aberdeen Group plc trimmed564,175$23M1.2%2026-Q1
BAKER BROS. ADVISORS LP400,000$16M0.9%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added389,872$16M0.8%2026-Q1
Siren, L.L.C.300,000$12M0.6%2026-Q1
Sio Capital Management, LLC new294,340$12M0.6%2026-Q1
Soleus Capital Management, L.P. added293,500$12M0.6%2026-Q1
GOLDMAN SACHS GROUP INC added263,174$11M0.6%2026-Q1
Ensign Peak Advisors, Inc added255,636$10M0.5%2026-Q1
Candriam S.C.A. new236,813$9M0.5%2026-Q1
Kalehua Capital Management LLC197,072$8M0.4%2026-Q1
FRANKLIN RESOURCES INC175,483$7M0.4%2026-Q1
ADAGE CAPITAL PARTNERS GP, L.L.C. new150,000$6M0.3%2026-Q1
UBS Group AG added147,641$6M0.3%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new142,081$6M0.3%2026-Q1
SUPERSTRING CAPITAL MANAGEMENT LP trimmed141,024$6M0.3%2026-Q1
MILLENNIUM MANAGEMENT LLC added140,641$6M0.3%2026-Q1
Point72 Asset Management, L.P. new136,549$5M0.3%2026-Q1
Alyeska Investment Group, L.P.136,222$5M0.3%2026-Q1
GordonMD Global Investments LP new136,000$5M0.3%2026-Q1
MORGAN STANLEY added133,023$5M0.3%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed120,253$5M0.3%2026-Q1
Artia Global Partners LP119,741$5M0.3%2026-Q1
NORTHERN TRUST CORP added116,776$5M0.2%2026-Q1
VANGUARD FIDUCIARY TRUST CO new112,175$4M0.2%2026-Q1
Rock Springs Capital Management LP99,429$4M0.2%2026-Q1
Rhenman & Partners Asset Management AB new87,500$4M0.2%2026-Q1
TD Asset Management Inc trimmed82,996$3M0.2%2026-Q1
AMERIPRISE FINANCIAL INC trimmed81,974$3M0.2%2026-Q1
FMR LLC added81,395$3M0.2%2026-Q1
Driehaus Capital Management LLC trimmed76,633$3M0.2%2026-Q1
MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed64,458$3M0.1%2026-Q1
BANK OF AMERICA CORP /DE/ added50,870$2M0.1%2026-Q1
SEVEN GRAND MANAGERS, LLC50,000$2M0.1%2026-Q1
Integral Health Asset Management, LLC new50,000$2M0.1%2026-Q1
Ishara Investments LP new49,200$2M0.1%2026-Q1
Russell Investments Group, Ltd. added48,419$2M0.1%2026-Q1
WELLINGTON MANAGEMENT GROUP LLP added46,079$2M0.1%2026-Q1
Qube Research & Technologies Ltd new42,242$2M0.1%2026-Q1
BNP PARIBAS FINANCIAL MARKETS added40,570$2M0.1%2026-Q1
SILVERARC CAPITAL MANAGEMENT, LLC trimmed39,417$2M0.1%2026-Q1
ALPS ADVISORS INC trimmed36,628$1M0.1%2026-Q1
STEMPOINT CAPITAL LP trimmed36,540$1M0.1%2026-Q1
Bank of New York Mellon Corp trimmed33,778$1M0.1%2026-Q1
POLEN CAPITAL MANAGEMENT LLC trimmed26,775$1M0.1%2026-Q1
Maven Securities LTD new25,000$1M0.1%2026-Q1
Nuveen, LLC23,734$951K0.1%2026-Q1
XTX Topco Ltd added23,551$944K0.1%2026-Q1
Rafferty Asset Management, LLC trimmed22,137$887K0.0%2026-Q1
BARCLAYS PLC trimmed18,385$737K0.0%2026-Q1
RHUMBLINE ADVISERS added18,308$734K0.0%2026-Q1
CITIGROUP INC added18,058$724K0.0%2026-Q1
ALLIANCEBERNSTEIN L.P. added16,410$675K0.0%2026-Q1
Squarepoint Ops LLC trimmed15,217$610K0.0%2026-Q1
Walleye Capital LLC new15,097$605K0.0%2026-Q1
DEUTSCHE BANK AG\ added13,249$531K0.0%2026-Q1
Longaeva Partners L.P. trimmed12,693$509K0.0%2026-Q1
KENNEDY CAPITAL MANAGEMENT LLC added12,284$492K0.0%2026-Q1
Vanguard Global Advisers, LLC new11,191$449K0.0%2026-Q1
Invesco Ltd. trimmed10,787$432K0.0%2026-Q1
PROFUND ADVISORS LLC added9,939$398K0.0%2026-Q1
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added9,185$363K0.0%2026-Q1
MetLife Investment Management, LLC8,565$343K0.0%2026-Q1
China Universal Asset Management Co., Ltd. trimmed7,920$318K0.0%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed7,310$293K0.0%2026-Q1
ExodusPoint Capital Management, LP new7,190$288K0.0%2026-Q1
VARCOV Co. new6,571$263K0.0%2026-Q1
Virtus Investment Advisers, LLC added6,374$256K0.0%2026-Q1
Quarry LP new6,304$253K0.0%2026-Q1
Hudson Bay Capital Management LP new6,180$248K0.0%2026-Q1
VANGUARD GROUP INC trimmed1,070,817$44M2.3%2025-Q4 stale
BRAIDWELL LP trimmed314,013$9M0.5%2025-Q3 stale
Zimmer Partners, LP new237,500$2M0.1%2025-Q1 stale
PRUDENTIAL FINANCIAL INC added135,185$2M0.1%2025-Q2 stale
Holocene Advisors, LP50,000$1M0.1%2025-Q3 stale
Woodline Partners LP80,000$1M0.1%2025-Q2 stale
CenterBook Partners LP new114,284$1M0.1%2025-Q1 stale
MARSHALL WACE, LLP added30,103$885K0.0%2025-Q3 stale
SG Americas Securities, LLC new10,691$440K0.0%2025-Q4 stale
RENAISSANCE TECHNOLOGIES LLC trimmed14,600$429K0.0%2025-Q3 stale
BOSUN ASSET MANAGEMENT, LLC new16,975$295K0.0%2025-Q2 stale
AMERICAN CENTURY COMPANIES INC new6,180$254K0.0%2025-Q4 stale
Jain Global LLC new8,513$250K0.0%2025-Q3 stale
DARK FOREST CAPITAL MANAGEMENT LP new5,991$246K0.0%2025-Q4 stale
COMMONWEALTH EQUITY SERVICES, LLC new14,017$243K0.0%2025-Q2 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership