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Institutional Ownership · SEC Form 13F

Who owns Rhythm Pharmaceuticals (RYTM)


Which tracked institutional funds hold RYTM, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See RYTM company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

288
Institutional holders
77M
Shares held (tracked funds)

How the tape is positioned

132 tracked funds added or opened RYTM while 51 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

RYTM’s largest tracked holder by dollar value, RA CAPITAL MANAGEMENT, L.P., sizes it at 6.4% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 6.4pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in RYTM divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 288 tracked filers holding RYTM, 165 increased or opened the position and 153 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in RYTM between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 23

  • Jupiter Topco LLC$103M
  • Duquesne Family Office LLC$23M
  • Assenagon Asset Management S.A.$21M
  • First Turn Management, LLC$17M
  • Nicholas Investment Partners, LP$15M
  • SEGALL BRYANT & HAMILL, LLC$14M

Full exits 22

  • JANUS HENDERSON GROUP PLC$80M
  • LORD, ABBETT & CO. LLC$30M
  • Hood River Capital Management LLC$21M
  • M&G PLC$12M
  • BALYASNY ASSET MANAGEMENT L.P.$5M
  • CASTLEARK MANAGEMENT LLC$5M

Largest adds

  • BlackRock, Inc.$327M
  • JPMORGAN CHASE & CO$172M
  • RA CAPITAL MANAGEMENT, L.P.$160M
  • PRICE T ROWE ASSOCIATES INC /MD/$141M
  • BAKER BROS. ADVISORS LP$135M
  • STATE STREET CORP$88M

Largest trims

  • FMR LLC$30M
  • Point72 Asset Management, L.P.$28M
  • Logos Global Management LP$25M
  • Driehaus Capital Management LLC$24M
  • Opaleye Management Inc.$22M
  • ALLIANCEBERNSTEIN L.P.$20M

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
RA CAPITAL MANAGEMENT, L.P.6,666,837$740M8.9%2026-Q2
BlackRock, Inc. added6,156,902$684M8.2%2026-Q2
BAKER BROS. ADVISORS LP5,604,483$622M7.4%2026-Q2
PRIMECAP MANAGEMENT CO/CA/ trimmed3,168,853$352M4.2%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC added3,136,895$348M4.2%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added3,005,977$334M4.0%2026-Q2
JPMORGAN CHASE & CO added2,652,746$292M3.5%2026-Q2
PERCEPTIVE ADVISORS LLC added2,586,295$287M3.4%2026-Q2
STATE STREET CORP added2,573,529$286M3.4%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ added2,566,171$285M3.4%2026-Q2
WESTFIELD CAPITAL MANAGEMENT CO LP added2,208,595$245M2.9%2026-Q2
GOLDMAN SACHS GROUP INC added2,126,502$236M2.8%2026-Q2
FEDERATED HERMES, INC. added1,785,716$198M2.4%2026-Q2
Polar Capital Holdings Plc added1,663,632$185M2.2%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added1,533,698$170M2.0%2026-Q2
Capital Research Global Investors added1,532,303$170M2.0%2026-Q2
CITADEL ADVISORS LLC trimmed1,263,652$140M1.7%2026-Q2
Checkpoint Capital L.P. trimmed1,186,000$132M1.6%2026-Q2
Siren, L.L.C. added1,136,275$126M1.5%2026-Q2
MORGAN STANLEY added1,112,240$123M1.5%2026-Q2
FMR LLC trimmed1,025,840$114M1.4%2026-Q2
Pictet Asset Management Holding SA added957,785$106M1.3%2026-Q2
Jupiter Topco LLC new925,490$103M1.2%2026-Q2
ALLIANCEBERNSTEIN L.P. trimmed894,723$78M0.9%2026-Q2
Woodline Partners LP758,891$84M1.0%2026-Q2
Clearbridge Investments, LLC added696,473$77M0.9%2026-Q2
Rock Springs Capital Management LP added692,598$77M0.9%2026-Q2
NORGES BANK added685,844$76M0.9%2026-Q2
FRANKLIN RESOURCES INC trimmed577,033$64M0.8%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added552,738$61M0.7%2026-Q2
Integral Health Asset Management, LLC trimmed550,000$61M0.7%2026-Q2
Invesco Ltd. added543,271$60M0.7%2026-Q2
NORTHERN TRUST CORP added540,332$60M0.7%2026-Q2
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed514,850$57M0.7%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP added488,747$54M0.6%2026-Q2
VANGUARD FIDUCIARY TRUST CO added445,723$49M0.6%2026-Q2
LOOMIS SAYLES & CO L P trimmed434,102$48M0.6%2026-Q2
Candriam S.C.A. trimmed433,025$48M0.6%2026-Q2
Squarepoint Ops LLC added422,921$47M0.6%2026-Q2
Point72 Asset Management, L.P. trimmed414,210$46M0.6%2026-Q2
Sofinnova Investments, Inc. trimmed408,027$45M0.5%2026-Q2
AMERIPRISE FINANCIAL INC added401,634$45M0.5%2026-Q2
ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed397,000$44M0.5%2026-Q2
Bank of New York Mellon Corp added394,044$44M0.5%2026-Q2
BRAIDWELL LP added381,128$42M0.5%2026-Q2
Artisan Partners Limited Partnership trimmed354,816$39M0.5%2026-Q2
BANK OF AMERICA CORP /DE/ trimmed325,470$36M0.4%2026-Q2
ORBIMED ADVISORS LLC added322,900$36M0.4%2026-Q2
MILLENNIUM MANAGEMENT LLC trimmed316,719$35M0.4%2026-Q2
SILVERARC CAPITAL MANAGEMENT, LLC added311,461$35M0.4%2026-Q2
VOYA INVESTMENT MANAGEMENT LLC added272,974$30M0.4%2026-Q2
Capital World Investors added221,450$25M0.3%2026-Q2
Duquesne Family Office LLC new203,618$23M0.3%2026-Q2
Nuveen, LLC added203,078$23M0.3%2026-Q2
BNP PARIBAS FINANCIAL MARKETS trimmed197,374$22M0.3%2026-Q2
KENNEDY CAPITAL MANAGEMENT LLC added193,215$21M0.3%2026-Q2
Assenagon Asset Management S.A. trimmed186,491$21M0.2%2026-Q2
SCHRODER INVESTMENT MANAGEMENT GROUP added160,518$18M0.2%2026-Q2
First Turn Management, LLC added154,018$17M0.2%2026-Q2
NEW YORK STATE COMMON RETIREMENT FUND added148,152$16M0.2%2026-Q2
UBS Group AG trimmed144,378$16M0.2%2026-Q2
Nicholas Investment Partners, LP added139,270$15M0.2%2026-Q2
ADAR1 Capital Management, LLC trimmed136,158$15M0.2%2026-Q2
Connor, Clark & Lunn Investment Management Ltd. trimmed135,867$15M0.2%2026-Q2
Qube Research & Technologies Ltd trimmed134,410$15M0.2%2026-Q2
NEXTBio Capital Management LP added131,758$15M0.2%2026-Q2
Driehaus Capital Management LLC trimmed129,285$14M0.2%2026-Q2
SummitTX Capital, L.P. trimmed126,401$14M0.2%2026-Q2
Logos Global Management LP trimmed125,000$14M0.2%2026-Q2
Opaleye Management Inc. trimmed122,500$14M0.2%2026-Q2
SEGALL BRYANT & HAMILL, LLC new121,866$14M0.2%2026-Q2
DEUTSCHE BANK AG\ trimmed115,232$13M0.2%2026-Q2
Longaeva Partners L.P. new110,074$12M0.1%2026-Q2
Swiss National Bank trimmed109,700$12M0.1%2026-Q2
PFM Health Sciences, LP trimmed101,550$11M0.1%2026-Q2
Aberdeen Group plc added94,946$11M0.1%2026-Q2
AXIOM INVESTORS LLC /DE trimmed86,880$10M0.1%2026-Q2
Russell Investments Group, Ltd. trimmed86,709$10M0.1%2026-Q2
First Light Asset Management, LLC trimmed85,765$10M0.1%2026-Q2
ALGERT GLOBAL LLC added83,431$9M0.1%2026-Q2
Granahan Investment Management, LLC added83,270$9M0.1%2026-Q2
NEUBERGER BERMAN GROUP LLC added83,035$9M0.1%2026-Q2
WCM INVESTMENT MANAGEMENT, LLC trimmed80,552$9M0.1%2026-Q2
SPHERA FUNDS MANAGEMENT LTD. new80,400$9M0.1%2026-Q2
Atom Investors LP added73,465$8M0.1%2026-Q2
SILVERCREST ASSET MANAGEMENT GROUP LLC added73,432$8M0.1%2026-Q2
RHUMBLINE ADVISERS added73,333$8M0.1%2026-Q2
WELLS FARGO & COMPANY/MN added72,147$8M0.1%2026-Q2
PRUDENTIAL FINANCIAL INC added69,145$8M0.1%2026-Q2
CAPITAL FUND MANAGEMENT S.A. new68,548$8M0.1%2026-Q2
RENAISSANCE TECHNOLOGIES LLC trimmed68,281$8M0.1%2026-Q2
PICTON MAHONEY ASSET MANAGEMENT added65,880$7M0.1%2026-Q2
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM trimmed64,031$7M0.1%2026-Q2
Blue Owl Capital Holdings LP61,455$7M0.1%2026-Q2
ExodusPoint Capital Management, LP added61,147$7M0.1%2026-Q2
AQR CAPITAL MANAGEMENT LLC added59,208$7M0.1%2026-Q2
CITIGROUP INC added58,347$6M0.1%2026-Q2
RAYMOND JAMES FINANCIAL INC added58,069$6M0.1%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE added57,170$6M0.1%2026-Q2
Trexquant Investment LP added56,248$6M0.1%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership