Who owns uniQure N.V. (QURE)
Which tracked institutional funds hold QURE, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See QURE company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-19). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
44 tracked funds added or opened QURE while 97 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
QURE’s largest tracked holder by dollar value, EcoR1 Capital, LLC, sizes it at 10.0% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 9.8pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in QURE divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 211 tracked filers holding QURE, 118 increased or opened the position and 121 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in QURE between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 22
- Two Seas Capital LP$21M
- Siren, L.L.C.$16M
- VANGUARD CAPITAL MANAGEMENT LLC$11M
- JANE STREET GROUP, LLC$10M
- MAK CAPITAL ONE LLC$7M
- Vestal Point Capital, LP$6M
Full exits 28
- SUVRETTA CAPITAL MANAGEMENT, LLC$29M
- TWO SIGMA ADVISERS, LP$27M
- VANGUARD GROUP INC$25M
- Artia Global Partners LP$24M
- Logos Global Management LP$16M
- Tyro Capital Management LLC$16M
Largest adds
- ORBIMED ADVISORS LLC$17M
- BALYASNY ASSET MANAGEMENT L.P.$13M
- SG Americas Securities, LLC$11M
- TWO SIGMA INVESTMENTS, LP$9M
- Massar Capital Management, LP$6M
- ExodusPoint Capital Management, LP$5M
Largest trims
- FMR LLC$122M
- Avoro Capital Advisors LLC$50M
- RTW INVESTMENTS, LP$47M
- STATE STREET CORP$40M
- JPMORGAN CHASE & CO$28M
- BlackRock, Inc.$19M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Avoro Capital Advisors LLC trimmed | 5,959,595 | $97M | 6.6% | 2026-Q1 |
| Aberdeen Group plc added | 5,306,386 | $87M | 5.8% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP added | 2,675,871 | $44M | 2.9% | 2026-Q1 |
| RTW INVESTMENTS, LP trimmed | 2,586,356 | $42M | 2.8% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 2,837,466 | $42M | 2.8% | 2026-Q1 |
| STATE STREET CORP trimmed | 2,260,512 | $37M | 2.5% | 2026-Q1 |
| ORBIMED ADVISORS LLC added | 2,136,149 | $35M | 2.3% | 2026-Q1 |
| BlackRock, Inc. trimmed | 1,733,458 | $28M | 1.9% | 2026-Q1 |
| FMR LLC trimmed | 1,677,498 | $27M | 1.8% | 2026-Q1 |
| MPM BIOIMPACT LLC trimmed | 1,369,231 | $22M | 1.5% | 2026-Q1 |
| Two Seas Capital LP new | 1,300,000 | $21M | 1.4% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 1,263,236 | $21M | 1.4% | 2026-Q1 |
| JENNISON ASSOCIATES LLC trimmed | 1,233,789 | $20M | 1.4% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 1,002,800 | $16M | 1.1% | 2026-Q1 |
| Siren, L.L.C. added | 1,000,000 | $16M | 1.1% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. added | 964,290 | $16M | 1.1% | 2026-Q1 |
| Integral Health Asset Management, LLC | 900,000 | $15M | 1.0% | 2026-Q1 |
| Fiera Capital Corp added | 816,893 | $13M | 0.9% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 804,610 | $13M | 0.9% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC trimmed | 792,756 | $13M | 0.9% | 2026-Q1 |
| SG Americas Securities, LLC added | 776,604 | $13M | 0.9% | 2026-Q1 |
| MAVERICK CAPITAL LTD added | 697,640 | $11M | 0.8% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 694,721 | $11M | 0.8% | 2026-Q1 |
| Boxer Capital Management, LLC added | 662,000 | $11M | 0.7% | 2026-Q1 |
| Whitefort Capital Management, LP added | 657,611 | $11M | 0.7% | 2026-Q1 |
| JANE STREET GROUP, LLC added | 635,995 | $10M | 0.7% | 2026-Q1 |
| First Turn Management, LLC added | 615,489 | $10M | 0.7% | 2026-Q1 |
| Voss Capital, LP added | 605,000 | $10M | 0.7% | 2026-Q1 |
| CITIGROUP INC added | 531,885 | $9M | 0.6% | 2026-Q1 |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 521,677 | $9M | 0.6% | 2026-Q1 |
| READYSTATE ASSET MANAGEMENT LP added | 504,702 | $8M | 0.6% | 2026-Q1 |
| 683 Capital Management, LLC added | 500,000 | $8M | 0.5% | 2026-Q1 |
| Catalio Capital Management, LP added | 491,116 | $8M | 0.5% | 2026-Q1 |
| UBS Group AG trimmed | 487,838 | $8M | 0.5% | 2026-Q1 |
| Privium Fund Management B.V. added | 486,520 | $8M | 0.5% | 2026-Q1 |
| FRANKLIN RESOURCES INC trimmed | 480,866 | $8M | 0.5% | 2026-Q1 |
| MAK CAPITAL ONE LLC new | 441,205 | $7M | 0.5% | 2026-Q1 |
| ExodusPoint Capital Management, LP added | 436,467 | $7M | 0.5% | 2026-Q1 |
| Massar Capital Management, LP added | 426,029 | $7M | 0.5% | 2026-Q1 |
| CITADEL ADVISORS LLC trimmed | 404,565 | $7M | 0.4% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 375,852 | $6M | 0.4% | 2026-Q1 |
| MORGAN STANLEY trimmed | 366,117 | $6M | 0.4% | 2026-Q1 |
| Vestal Point Capital, LP added | 358,996 | $6M | 0.4% | 2026-Q1 |
| Squarepoint Ops LLC added | 345,983 | $6M | 0.4% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 332,523 | $5M | 0.4% | 2026-Q1 |
| Caption Management, LLC added | 303,231 | $5M | 0.3% | 2026-Q1 |
| Engineers Gate Manager LP added | 299,757 | $5M | 0.3% | 2026-Q1 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 258,211 | $4M | 0.3% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ trimmed | 246,851 | $4M | 0.3% | 2026-Q1 |
| Nantahala Capital Management, LLC trimmed | 237,078 | $4M | 0.3% | 2026-Q1 |
| SIMPLEX TRADING, LLC added | 231,769 | $4M | 0.3% | 2026-Q1 |
| Kalehua Capital Management LLC new | 211,702 | $3M | 0.2% | 2026-Q1 |
| Parkman Healthcare Partners LLC trimmed | 206,842 | $3M | 0.2% | 2026-Q1 |
| GROUP ONE TRADING LLC added | 179,000 | $3M | 0.2% | 2026-Q1 |
| NORTHERN TRUST CORP added | 169,959 | $3M | 0.2% | 2026-Q1 |
| BARCLAYS PLC trimmed | 167,732 | $3M | 0.2% | 2026-Q1 |
| D. E. Shaw & Co., Inc. added | 160,714 | $3M | 0.2% | 2026-Q1 |
| Hudson Bay Capital Management LP added | 158,500 | $3M | 0.2% | 2026-Q1 |
| FLAX POND CAPITAL, LLC added | 152,031 | $2M | 0.2% | 2026-Q1 |
| Creek Drive Management Group LLC new | 150,000 | $2M | 0.2% | 2026-Q1 |
| NEW YORK STATE COMMON RETIREMENT FUND | 147,549 | $2M | 0.2% | 2026-Q1 |
| Assenagon Asset Management S.A. trimmed | 146,749 | $2M | 0.2% | 2026-Q1 |
| Susquehanna Portfolio Strategies, LLC added | 138,969 | $2M | 0.2% | 2026-Q1 |
| EcoR1 Capital, LLC | 3,988,971 | $233M | 15.7% | 2025-Q3 stale |
| SUVRETTA CAPITAL MANAGEMENT, LLC new | 1,216,734 | $29M | 2.0% | 2025-Q4 stale |
| Deep Track Capital, LP trimmed | 483,092 | $28M | 1.9% | 2025-Q3 stale |
| TWO SIGMA ADVISERS, LP added | 1,110,400 | $27M | 1.8% | 2025-Q4 stale |
| VANGUARD GROUP INC trimmed | 1,051,379 | $25M | 1.7% | 2025-Q4 stale |
| Artia Global Partners LP added | 1,023,539 | $24M | 1.6% | 2025-Q4 stale |
| Darwin Global Management, Ltd. new | 400,000 | $24M | 1.6% | 2025-Q3 stale |
| Logos Global Management LP added | 675,000 | $16M | 1.1% | 2025-Q4 stale |
| Tyro Capital Management LLC new | 663,929 | $16M | 1.1% | 2025-Q4 stale |
| MACQUARIE GROUP LTD trimmed | 258,211 | $15M | 1.0% | 2025-Q3 stale |
| EVENTIDE ASSET MANAGEMENT, LLC trimmed | 498,212 | $12M | 0.8% | 2025-Q4 stale |
| RA CAPITAL MANAGEMENT, L.P. added | 200,000 | $12M | 0.8% | 2025-Q3 stale |
| Soleus Capital Management, L.P. new | 200,000 | $12M | 0.8% | 2025-Q3 stale |
| LORD, ABBETT & CO. LLC trimmed | 176,025 | $10M | 0.7% | 2025-Q3 stale |
| BOONE CAPITAL MANAGEMENT LLC new | 147,317 | $9M | 0.6% | 2025-Q3 stale |
| Woodline Partners LP trimmed | 130,615 | $8M | 0.5% | 2025-Q3 stale |
| HRT FINANCIAL LP added | 310,050 | $7M | 0.5% | 2025-Q4 stale |
| Pale Fire Capital SE added | 529,798 | $7M | 0.5% | 2025-Q2 stale |
| Jump Financial, LLC added | 306,131 | $7M | 0.5% | 2025-Q4 stale |
| Rosalind Advisors, Inc. new | 125,000 | $7M | 0.5% | 2025-Q3 stale |
| Freshford Capital Management, LLC new | 229,613 | $5M | 0.4% | 2025-Q4 stale |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC added | 500,977 | $5M | 0.4% | 2025-Q1 stale |
| Atika Capital Management LLC added | 90,000 | $5M | 0.4% | 2025-Q3 stale |
| Eagle Health Investments LP new | 205,247 | $5M | 0.3% | 2025-Q4 stale |
| Patient Square Capital LP new | 75,000 | $4M | 0.3% | 2025-Q3 stale |
| Sofinnova Investments, Inc. added | 176,513 | $4M | 0.3% | 2025-Q4 stale |
| Apis Capital Advisors, LLC new | 63,800 | $4M | 0.3% | 2025-Q3 stale |
| Cubist Systematic Strategies, LLC trimmed | 62,365 | $4M | 0.2% | 2025-Q3 stale |
| Alyeska Investment Group, L.P. added | 151,058 | $4M | 0.2% | 2025-Q4 stale |
| Verition Fund Management LLC trimmed | 57,968 | $3M | 0.2% | 2025-Q3 stale |
| Longaeva Partners L.P. new | 55,000 | $3M | 0.2% | 2025-Q3 stale |
| SILVERARC CAPITAL MANAGEMENT, LLC trimmed | 126,047 | $3M | 0.2% | 2025-Q4 stale |
| Avidity Partners Management LP trimmed | 207,000 | $3M | 0.2% | 2025-Q2 stale |
| Owl Creek Asset Management, L.P. new | 49,389 | $3M | 0.2% | 2025-Q3 stale |
| ACADIAN ASSET MANAGEMENT LLC trimmed | 250,104 | $3M | 0.2% | 2025-Q1 stale |
| Monashee Investment Management LLC trimmed | 40,000 | $2M | 0.2% | 2025-Q3 stale |
| Jefferies Financial Group Inc. | 90,542 | $2M | 0.1% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.