Who owns uniQure (QURE)
Which tracked institutional funds hold QURE, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See QURE company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on QURE is one-sided between 2026-Q1 and 2026-Q2: 151 added or opened and 27 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
QURE’s largest tracked holder by dollar value, Avoro Capital Advisors LLC, sizes it at 2.8% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 2.7pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in QURE divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 245 tracked filers holding QURE, 170 increased or opened the position and 108 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in QURE between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 37
- Longaeva Partners L.P.$37M
- Invesco Ltd.$29M
- Point72 Asset Management, L.P.$28M
- Kinetic Partners Management, LP$27M
- GILDER GAGNON HOWE & CO LLC$24M
- Rubric Capital Management LP$19M
Full exits 22
- Siren, L.L.C.$16M
- SG Americas Securities, LLC$13M
- Whitefort Capital Management, LP$11M
- Catalio Capital Management, LP$8M
- ExodusPoint Capital Management, LP$7M
- GROUP ONE TRADING LLC$3M
Largest adds
- Avoro Capital Advisors LLC$212M
- JPMORGAN CHASE & CO$189M
- RTW INVESTMENTS, LP$139M
- STATE STREET CORP$97M
- JANE STREET GROUP, LLC$64M
- Boxer Capital Management, LLC$58M
Largest trims
- Caption Management, LLC$4M
- Massar Capital Management, LP$4M
- CITIGROUP INC$3M
- Engineers Gate Manager LP$2M
- BARCLAYS PLC$2M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Avoro Capital Advisors LLC added | 6,727,777 | $310M | 10.6% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 4,867,755 | $231M | 7.9% | 2026-Q2 |
| RTW INVESTMENTS, LP added | 3,941,572 | $182M | 6.2% | 2026-Q2 |
| STATE STREET CORP added | 2,903,825 | $134M | 4.6% | 2026-Q2 |
| Aberdeen Group plc trimmed | 2,848,117 | $131M | 4.5% | 2026-Q2 |
| BlackRock, Inc. added | 1,877,453 | $86M | 3.0% | 2026-Q2 |
| ORBIMED ADVISORS LLC trimmed | 1,807,486 | $83M | 2.8% | 2026-Q2 |
| JANE STREET GROUP, LLC added | 1,610,483 | $74M | 2.5% | 2026-Q2 |
| JENNISON ASSOCIATES LLC added | 1,561,412 | $72M | 2.5% | 2026-Q2 |
| Boxer Capital Management, LLC added | 1,503,300 | $69M | 2.4% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 1,475,956 | $68M | 2.3% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP trimmed | 1,462,024 | $67M | 2.3% | 2026-Q2 |
| Two Seas Capital LP added | 1,441,410 | $66M | 2.3% | 2026-Q2 |
| FMR LLC trimmed | 1,270,068 | $58M | 2.0% | 2026-Q2 |
| MAK CAPITAL ONE LLC added | 1,232,051 | $57M | 1.9% | 2026-Q2 |
| MPM BIOIMPACT LLC trimmed | 1,225,855 | $56M | 1.9% | 2026-Q2 |
| MORGAN STANLEY added | 1,066,639 | $49M | 1.7% | 2026-Q2 |
| Vestal Point Capital, LP added | 935,000 | $43M | 1.5% | 2026-Q2 |
| MAVERICK CAPITAL LTD added | 925,383 | $43M | 1.5% | 2026-Q2 |
| CITADEL ADVISORS LLC added | 910,338 | $42M | 1.4% | 2026-Q2 |
| Fiera Capital Corp added | 909,141 | $42M | 1.4% | 2026-Q2 |
| Integral Health Asset Management, LLC | 900,000 | $41M | 1.4% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 860,631 | $40M | 1.4% | 2026-Q2 |
| Longaeva Partners L.P. added | 804,594 | $37M | 1.3% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 779,779 | $36M | 1.2% | 2026-Q2 |
| Invesco Ltd. added | 627,823 | $29M | 1.0% | 2026-Q2 |
| First Turn Management, LLC trimmed | 608,925 | $28M | 1.0% | 2026-Q2 |
| Point72 Asset Management, L.P. added | 606,212 | $28M | 1.0% | 2026-Q2 |
| BALYASNY ASSET MANAGEMENT L.P. trimmed | 586,582 | $27M | 0.9% | 2026-Q2 |
| Kinetic Partners Management, LP new | 581,000 | $27M | 0.9% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 578,786 | $27M | 0.9% | 2026-Q2 |
| 683 Capital Management, LLC added | 575,000 | $26M | 0.9% | 2026-Q2 |
| GILDER GAGNON HOWE & CO LLC added | 530,979 | $24M | 0.8% | 2026-Q2 |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 521,677 | $24M | 0.8% | 2026-Q2 |
| Assenagon Asset Management S.A. added | 513,530 | $24M | 0.8% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 496,897 | $23M | 0.8% | 2026-Q2 |
| UBS Group AG trimmed | 467,571 | $22M | 0.7% | 2026-Q2 |
| Nantahala Capital Management, LLC added | 455,660 | $21M | 0.7% | 2026-Q2 |
| Voss Capital, LP trimmed | 450,361 | $21M | 0.7% | 2026-Q2 |
| Rubric Capital Management LP new | 408,581 | $19M | 0.6% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 403,338 | $19M | 0.6% | 2026-Q2 |
| READYSTATE ASSET MANAGEMENT LP trimmed | 400,989 | $18M | 0.6% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 369,607 | $17M | 0.6% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 343,126 | $16M | 0.5% | 2026-Q2 |
| Creek Drive Management Group LLC added | 337,000 | $16M | 0.5% | 2026-Q2 |
| TUDOR INVESTMENT CORP ET AL added | 328,889 | $15M | 0.5% | 2026-Q2 |
| Privium Fund Management B.V. trimmed | 328,322 | $15M | 0.5% | 2026-Q2 |
| ADAR1 Capital Management, LLC added | 324,672 | $15M | 0.5% | 2026-Q2 |
| MARSHALL WACE, LLP added | 304,702 | $14M | 0.5% | 2026-Q2 |
| BRAIDWELL LP new | 301,652 | $14M | 0.5% | 2026-Q2 |
| Squarepoint Ops LLC trimmed | 280,300 | $13M | 0.4% | 2026-Q2 |
| FRANKLIN RESOURCES INC trimmed | 245,272 | $11M | 0.4% | 2026-Q2 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 244,238 | $11M | 0.4% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. trimmed | 217,500 | $10M | 0.3% | 2026-Q2 |
| NORTHERN TRUST CORP added | 212,935 | $10M | 0.3% | 2026-Q2 |
| Parkman Healthcare Partners LLC added | 208,170 | $10M | 0.3% | 2026-Q2 |
| D. E. Shaw & Co., Inc. added | 207,629 | $10M | 0.3% | 2026-Q2 |
| Diametric Capital, LP added | 197,242 | $9M | 0.3% | 2026-Q2 |
| PICTON MAHONEY ASSET MANAGEMENT new | 181,215 | $8M | 0.3% | 2026-Q2 |
| Affinity Asset Advisors, LLC added | 175,000 | $8M | 0.3% | 2026-Q2 |
| Trexquant Investment LP added | 171,149 | $8M | 0.3% | 2026-Q2 |
| FLAX POND CAPITAL, LLC added | 168,031 | $3M | 0.1% | 2026-Q2 |
| PERCEPTIVE ADVISORS LLC added | 168,000 | $8M | 0.3% | 2026-Q2 |
| Freshford Capital Management, LLC trimmed | 161,855 | $7M | 0.3% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC added | 152,343 | $7M | 0.2% | 2026-Q2 |
| Casdin Capital, LLC new | 150,000 | $7M | 0.2% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 149,971 | $7M | 0.2% | 2026-Q2 |
| Hennion & Walsh Asset Management, Inc. added | 142,113 | $7M | 0.2% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 141,093 | $6M | 0.2% | 2026-Q2 |
| CITIGROUP INC trimmed | 127,944 | $6M | 0.2% | 2026-Q2 |
| ENVESTNET ASSET MANAGEMENT INC added | 126,576 | $6M | 0.2% | 2026-Q2 |
| ROYAL BANK OF CANADA added | 124,293 | $6M | 0.2% | 2026-Q2 |
| Susquehanna Portfolio Strategies, LLC trimmed | 121,869 | $6M | 0.2% | 2026-Q2 |
| Hudson Bay Capital Management LP trimmed | 120,000 | $6M | 0.2% | 2026-Q2 |
| NAN FUNG TRINITY (HK) LTD | 115,494 | $5M | 0.2% | 2026-Q2 |
| SIMPLEX TRADING, LLC trimmed | 110,219 | $5M | 0.2% | 2026-Q2 |
| SILVERARC CAPITAL MANAGEMENT, LLC trimmed | 105,000 | $5M | 0.2% | 2026-Q2 |
| Ghisallo Capital Management LLC new | 100,000 | $5M | 0.2% | 2026-Q2 |
| Pekin Hardy Strauss, Inc. trimmed | 94,250 | $4M | 0.1% | 2026-Q2 |
| Swiss National Bank added | 94,100 | $4M | 0.1% | 2026-Q2 |
| STEMPOINT CAPITAL LP added | 88,115 | $4M | 0.1% | 2026-Q2 |
| FourWorld Capital Management LLC new | 87,000 | $4M | 0.1% | 2026-Q2 |
| Marex Group Ltd added | 81,500 | $4M | 0.1% | 2026-Q2 |
| Exome Asset Management LLC added | 81,056 | $4M | 0.1% | 2026-Q2 |
| Kalehua Capital Management LLC trimmed | 79,407 | $4M | 0.1% | 2026-Q2 |
| K2 PRINCIPAL FUND, L.P. trimmed | 78,601 | $4M | 0.1% | 2026-Q2 |
| Alyeska Investment Group, L.P. trimmed | 75,000 | $3M | 0.1% | 2026-Q2 |
| Burkehill Global Management, LP added | 75,000 | $3M | 0.1% | 2026-Q2 |
| FRED ALGER MANAGEMENT, LLC added | 69,561 | $3M | 0.1% | 2026-Q2 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 67,428 | $3M | 0.1% | 2026-Q2 |
| XTX Topco Ltd added | 66,665 | $3M | 0.1% | 2026-Q2 |
| Rafferty Asset Management, LLC trimmed | 66,438 | $3M | 0.1% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 62,418 | $3M | 0.1% | 2026-Q2 |
| Massar Capital Management, LP trimmed | 61,314 | $3M | 0.1% | 2026-Q2 |
| Holocene Advisors, LP new | 59,856 | $3M | 0.1% | 2026-Q2 |
| Clearline Capital LP trimmed | 58,055 | $3M | 0.1% | 2026-Q2 |
| Engineers Gate Manager LP trimmed | 56,064 | $3M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 52,611 | $2M | 0.1% | 2026-Q2 |
| Walleye Capital LLC trimmed | 51,225 | $2M | 0.1% | 2026-Q2 |
| MONIMUS CAPITAL MANAGEMENT, LP added | 51,066 | $2M | 0.1% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.