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Institutional Ownership · SEC Form 13F

Who owns Q32 Bio (QTTB)


Which tracked institutional funds hold QTTB, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See QTTB company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

53
Institutional holders
9M
Shares held (tracked funds)
73.3%
Of shares outstanding

How the tape is positioned

The tracked-fund tape on QTTB is one-sided between 2025-Q4 and 2026-Q1: 15 added or opened and 1 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

QTTB’s largest tracked holder by dollar value, Point72 Asset Management, L.P., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in QTTB divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 53 tracked filers holding QTTB, 25 increased or opened the position and 20 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in QTTB between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 3

  • VANGUARD CAPITAL MANAGEMENT LLC$2M
  • MACKENZIE FINANCIAL CORP$2M
  • MONIMUS CAPITAL MANAGEMENT, LP$862K

Full exits 1

  • VANGUARD GROUP INC$1M

Largest adds

  • Opaleye Management Inc.$7M
  • ORBIMED ADVISORS LLC$7M
  • Atlas Venture Life Science Advisors, LLC$6M
  • Carlyle Group Inc.$3M
  • RENAISSANCE TECHNOLOGIES LLC$998K
  • ARCH Venture Management, LLC$993K

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
Point72 Asset Management, L.P. added1,173,396$15M18.3%2026-Q2
ORBIMED ADVISORS LLC2,252,987$14M17.7%2026-Q1
Atlas Venture Life Science Advisors, LLC2,092,106$13M16.4%2026-Q1
Opaleye Management Inc. added1,256,228$8M9.9%2026-Q1
Carlyle Group Inc.1,102,741$7M8.7%2026-Q1
RENAISSANCE TECHNOLOGIES LLC trimmed179,600$2M2.8%2026-Q2
ARCH Venture Management, LLC320,482$2M2.5%2026-Q1
ACORN CAPITAL ADVISORS, LLC trimmed315,052$2M2.5%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new306,401$2M2.4%2026-Q1
MACKENZIE FINANCIAL CORP new246,304$2M1.9%2026-Q1
Sanofi244,083$2M1.9%2026-Q1
BlackRock, Inc. added118,507$2M1.8%2026-Q2
ACADIAN ASSET MANAGEMENT LLC added172,586$1M1.4%2026-Q1
MONIMUS CAPITAL MANAGEMENT, LP new134,310$862K1.1%2026-Q1
MARSHALL WACE, LLP added67,045$854K1.0%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added118,152$759K0.9%2026-Q1
Pfizer Inc trimmed101,618$737K0.9%2026-Q1
STATE STREET CORP added52,214$665K0.8%2026-Q2
TWO SIGMA INVESTMENTS, LP added49,582$632K0.8%2026-Q2
JANE STREET GROUP, LLC added65,599$421K0.5%2026-Q1
VANGUARD FIDUCIARY TRUST CO new49,995$321K0.4%2026-Q1
MANGROVE PARTNERS IM, LLC new22,150$282K0.3%2026-Q2
Cambridge Investment Research Advisors, Inc. new35,025$225K0.3%2026-Q1
ADAR1 Capital Management, LLC added35,000$225K0.3%2026-Q1
Affinity Asset Advisors, LLC27,777$178K0.2%2026-Q1
NORTHERN TRUST CORP25,033$161K0.2%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. new12,342$157K0.2%2026-Q2
ExodusPoint Capital Management, LP new11,336$144K0.2%2026-Q2
Cetera Investment Advisers new20,695$133K0.2%2026-Q1
AMERICAN CENTURY COMPANIES INC new18,770$121K0.1%2026-Q1
CITADEL ADVISORS LLC trimmed15,481$99K0.1%2026-Q1
BRIDGEWAY CAPITAL MANAGEMENT, LLC new12,613$81K0.1%2026-Q1
MORGAN STANLEY added9,560$61K0.1%2026-Q1
EverSource Wealth Advisors, LLC trimmed1,110$48K0.1%2026-Q1
FMR LLC trimmed3,388$43K0.1%2026-Q2
ROYAL BANK OF CANADA added2,744$18K0.0%2026-Q1
FEDERATED HERMES, INC.2,273$15K0.0%2026-Q1
Vanguard Global Advisers, LLC new1,915$12K0.0%2026-Q1
Tower Research Capital LLC (TRC) added1,871$12K0.0%2026-Q1
Arax Advisory Partners added1,148$7K0.0%2026-Q1
Rockefeller Capital Management L.P.577$4K0.0%2026-Q1
JONES FINANCIAL COMPANIES LLLP500$4K0.0%2026-Q1
Russell Investments Group, Ltd.454$3K0.0%2026-Q1
BNP PARIBAS FINANCIAL MARKETS trimmed303$2K0.0%2026-Q1
UBS Group AG trimmed270$2K0.0%2026-Q1
NISA INVESTMENT ADVISORS, LLC166$1K0.0%2026-Q1
OSAIC HOLDINGS, INC. trimmed124$7960.0%2026-Q1
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO added111$7130.0%2026-Q1
SBI Securities Co., Ltd. trimmed104$6680.0%2026-Q1
Allworth Financial LP98$6300.0%2026-Q1
WELLS FARGO & COMPANY/MN trimmed84$5390.0%2026-Q1
Federation des caisses Desjardins du Quebec70$4460.0%2026-Q1
CWM, LLC trimmed39$2500.0%2026-Q1
GROUP ONE TRADING LLC34$2180.0%2026-Q1
HARBOUR INVESTMENTS, INC.11$710.0%2026-Q1
VANGUARD GROUP INC added321,051$1M1.3%2025-Q4 stale
Trustees of Columbia University in the City of New York133,903$265K0.3%2025-Q3 stale
MILLENNIUM MANAGEMENT LLC trimmed51,268$170K0.2%2025-Q4 stale
Monaco Asset Management SAM trimmed50,919$169K0.2%2025-Q4 stale
GOLDMAN SACHS GROUP INC added63,539$95K0.1%2025-Q2 stale
Nuveen, LLC new55,886$92K0.1%2025-Q1 stale
HRT FINANCIAL LP added24,698$81K0.1%2025-Q4 stale
XTX Topco Ltd new20,353$68K0.1%2025-Q4 stale
Scientech Research LLC new15,510$51K0.1%2025-Q4 stale
DEUTSCHE BANK AG\25,018$41K0.1%2025-Q1 stale
AQR CAPITAL MANAGEMENT LLC trimmed26,530$40K0.0%2025-Q2 stale
TWO SIGMA SECURITIES, LLC new13,749$27K0.0%2025-Q3 stale
Bank of New York Mellon Corp added16,192$27K0.0%2025-Q1 stale
Squarepoint Ops LLC trimmed14,528$24K0.0%2025-Q1 stale
CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed14,190$23K0.0%2025-Q1 stale
DLK Investment Management, LLC10,333$20K0.0%2025-Q3 stale
OPPENHEIMER & CO INC new13,000$19K0.0%2025-Q2 stale
SUSQUEHANNA INTERNATIONAL GROUP, LLP added12,909$19K0.0%2025-Q2 stale
Corton Capital Inc. new11,607$19K0.0%2025-Q1 stale
RHUMBLINE ADVISERS trimmed11,156$18K0.0%2025-Q1 stale
Mariner, LLC trimmed11,780$18K0.0%2025-Q2 stale
RAYMOND JAMES FINANCIAL INC10,746$16K0.0%2025-Q2 stale
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added3,619$6K0.0%2025-Q1 stale
Global Retirement Partners, LLC trimmed1,500$5K0.0%2025-Q4 stale
Corebridge Financial, Inc. trimmed2,986$5K0.0%2025-Q1 stale
China Universal Asset Management Co., Ltd. trimmed2,138$4K0.0%2025-Q3 stale
NEW YORK STATE COMMON RETIREMENT FUND2,400$4K0.0%2025-Q1 stale
BANK OF AMERICA CORP /DE/ trimmed1,035$3K0.0%2025-Q4 stale
Police & Firemen's Retirement System of New Jersey1,228$2K0.0%2025-Q1 stale
COLDSTREAM CAPITAL MANAGEMENT INC new1,114$2K0.0%2025-Q1 stale
JPMORGAN CHASE & CO added324$1K0.0%2025-Q4 stale
SIMPLEX TRADING, LLC new813$1K0.0%2025-Q2 stale
Ameritas Investment Partners, Inc.591$9750.0%2025-Q1 stale
Mirae Asset Global Investments Co., Ltd. added472$9350.0%2025-Q3 stale
Fortitude Family Office, LLC562$9270.0%2025-Q1 stale
Legal & General Group Plc523$8630.0%2025-Q1 stale
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM437$7210.0%2025-Q1 stale
CITIGROUP INC trimmed236$4670.0%2025-Q3 stale
GF FUND MANAGEMENT CO. LTD. trimmed227$4490.0%2025-Q3 stale
Clark Wealth Partners199$2970.0%2025-Q2 stale
CoreCap Advisors, LLC107$1770.0%2025-Q1 stale
Sterling Capital Management LLC trimmed105$1730.0%2025-Q1 stale
True Wealth Design, LLC added67$1000.0%2025-Q2 stale
BARCLAYS PLC trimmed19$630.0%2025-Q4 stale
ST GERMAIN D J CO INC11$220.0%2025-Q3 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership