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Institutional Ownership · SEC Form 13F

Who owns Q32 Bio (QTTB)


Which tracked institutional funds hold QTTB, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See QTTB company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

68
Institutional holders
22M
Shares held (tracked funds)

How the tape is positioned

The tracked-fund tape on QTTB is one-sided between 2026-Q1 and 2026-Q2: 27 added or opened and 5 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

QTTB’s largest tracked holder by dollar value, ORBIMED ADVISORS LLC, sizes it at 1.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 1.0pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in QTTB divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 68 tracked filers holding QTTB, 43 increased or opened the position and 23 reduced or closed it; over the same quarter, open-market insider Form 4s were net purchases.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in QTTB between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 9

  • Boxer Capital Management, LLC$40M
  • BVF INC/IL$30M
  • RA CAPITAL MANAGEMENT, L.P.$30M
  • Point72 Asset Management, L.P.$15M
  • Logos Global Management LP$10M
  • SummitTX Capital, L.P.$9M

Full exits 4

  • ARCH Venture Management, LLC$2M
  • MACKENZIE FINANCIAL CORP$2M
  • ACADIAN ASSET MANAGEMENT LLC$1M
  • Pfizer Inc$737K

Largest adds

  • ORBIMED ADVISORS LLC$38M
  • Atlas Venture Life Science Advisors, LLC$21M
  • VANGUARD CAPITAL MANAGEMENT LLC$5M
  • Opaleye Management Inc.$4M
  • AMERICAN CENTURY COMPANIES INC$3M
  • JANE STREET GROUP, LLC$2M

Largest trims

  • Carlyle Group Inc.$6M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
ORBIMED ADVISORS LLC added4,127,987$53M18.3%2026-Q2
Boxer Capital Management, LLC new3,149,310$40M14.0%2026-Q2
Atlas Venture Life Science Advisors, LLC added2,717,106$35M12.0%2026-Q2
BVF INC/IL new2,350,000$30M10.4%2026-Q2
RA CAPITAL MANAGEMENT, L.P. new2,332,457$30M10.3%2026-Q2
Point72 Asset Management, L.P. added1,173,396$15M5.2%2026-Q2
Opaleye Management Inc. trimmed931,000$12M4.1%2026-Q2
Logos Global Management LP new800,000$10M3.5%2026-Q2
SummitTX Capital, L.P. new733,774$9M3.3%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added518,803$7M2.3%2026-Q2
Ikarian Capital, LLC new430,000$5M1.9%2026-Q2
Woodline Partners LP added286,212$4M1.3%2026-Q2
AMERICAN CENTURY COMPANIES INC added272,752$3M1.2%2026-Q2
Sanofi244,083$3M1.1%2026-Q2
ACORN CAPITAL ADVISORS, LLC trimmed216,171$3M1.0%2026-Q2
RENAISSANCE TECHNOLOGIES LLC trimmed179,600$2M0.8%2026-Q2
JANE STREET GROUP, LLC added162,747$2M0.7%2026-Q2
MONIMUS CAPITAL MANAGEMENT, LP trimmed132,036$2M0.6%2026-Q2
BOOTHBAY FUND MANAGEMENT, LLC new130,427$2M0.6%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added122,690$2M0.5%2026-Q2
CITADEL ADVISORS LLC added120,663$2M0.5%2026-Q2
BlackRock, Inc. added118,507$2M0.5%2026-Q2
MARSHALL WACE, LLP added67,045$854K0.3%2026-Q2
VANGUARD FIDUCIARY TRUST CO added66,217$844K0.3%2026-Q2
Carlyle Group Inc. trimmed60,363$769K0.3%2026-Q2
STATE STREET CORP added52,214$665K0.2%2026-Q2
TWO SIGMA INVESTMENTS, LP added49,582$632K0.2%2026-Q2
Quadrature Capital Ltd new36,396$464K0.2%2026-Q2
BRIDGEWAY CAPITAL MANAGEMENT, LLC added34,613$441K0.2%2026-Q2
DAFNA Capital Management LLC new32,896$419K0.1%2026-Q2
Knott David M Jr new30,412$387K0.1%2026-Q2
Affinity Asset Advisors, LLC27,777$354K0.1%2026-Q2
Squarepoint Ops LLC added23,790$303K0.1%2026-Q2
NORTHERN TRUST CORP trimmed23,631$301K0.1%2026-Q2
DIMENSIONAL FUND ADVISORS LP new23,588$301K0.1%2026-Q2
SUSQUEHANNA INTERNATIONAL GROUP, LLP added23,342$297K0.1%2026-Q2
MANGROVE PARTNERS IM, LLC new22,150$282K0.1%2026-Q2
LPL Financial LLC new18,170$231K0.1%2026-Q2
UBS Group AG added15,008$191K0.1%2026-Q2
BALYASNY ASSET MANAGEMENT L.P. new12,342$157K0.1%2026-Q2
ExodusPoint Capital Management, LP new11,336$144K0.1%2026-Q2
MILLENNIUM MANAGEMENT LLC trimmed10,928$139K0.0%2026-Q2
XTX Topco Ltd trimmed10,874$139K0.0%2026-Q2
MORGAN STANLEY trimmed6,456$82K0.0%2026-Q2
Vanguard Global Advisers, LLC added4,824$61K0.0%2026-Q2
FMR LLC trimmed3,388$43K0.0%2026-Q2
CITIGROUP INC added2,888$37K0.0%2026-Q2
Private Wealth Asset Management, LLC new1,700$22K0.0%2026-Q2
Arax Advisory Partners trimmed1,111$14K0.0%2026-Q2
FEDERATED HERMES, INC. trimmed1,050$13K0.0%2026-Q2
Rockefeller Capital Management L.P.577$7K0.0%2026-Q2
JONES FINANCIAL COMPANIES LLLP500$7K0.0%2026-Q2
Russell Investments Group, Ltd.454$6K0.0%2026-Q2
BNP PARIBAS FINANCIAL MARKETS303$4K0.0%2026-Q2
EverSource Wealth Advisors, LLC trimmed240$3K0.0%2026-Q2
NISA INVESTMENT ADVISORS, LLC166$2K0.0%2026-Q2
Truvestments Capital LLC new162$2K0.0%2026-Q2
OSAIC HOLDINGS, INC.124$2K0.0%2026-Q2
Allworth Financial LP added108$1K0.0%2026-Q2
SBI Securities Co., Ltd. trimmed94$1K0.0%2026-Q2
Federation des caisses Desjardins du Quebec70$8880.0%2026-Q2
Clearstead Advisors, LLC new67$8540.0%2026-Q2
Caitong International Asset Management Co., Ltd added45$5730.0%2026-Q2
GROUP ONE TRADING LLC34$4330.0%2026-Q2
HARBOUR INVESTMENTS, INC.11$1400.0%2026-Q2
AdvisorNet Financial, Inc2$250.0%2026-Q2
DANSKE BANK A/S1$130.0%2026-Q2
ROYAL BANK OF CANADA trimmed43—0.0%2026-Q2
ARCH Venture Management, LLC320,482$2M0.7%2026-Q1 stale (1 quarter behind)
MACKENZIE FINANCIAL CORP new246,304$2M0.6%2026-Q1 stale (1 quarter behind)
ACADIAN ASSET MANAGEMENT LLC added172,586$1M0.4%2026-Q1 stale (1 quarter behind)
Pfizer Inc trimmed101,618$737K0.3%2026-Q1 stale (1 quarter behind)
Cambridge Investment Research Advisors, Inc. new35,025$225K0.1%2026-Q1 stale (1 quarter behind)
ADAR1 Capital Management, LLC added35,000$225K0.1%2026-Q1 stale (1 quarter behind)
Cetera Investment Advisers new20,695$133K0.0%2026-Q1 stale (1 quarter behind)
Tower Research Capital LLC (TRC) added1,871$12K0.0%2026-Q1 stale (1 quarter behind)
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO added111$7130.0%2026-Q1 stale (1 quarter behind)
WELLS FARGO & COMPANY/MN trimmed84$5390.0%2026-Q1 stale (1 quarter behind)
CWM, LLC trimmed39$2500.0%2026-Q1 stale (1 quarter behind)
VANGUARD GROUP INC added321,051$1M0.4%2025-Q4 stale (2 quarters behind)
Monaco Asset Management SAM trimmed50,919$169K0.1%2025-Q4 stale (2 quarters behind)
HRT FINANCIAL LP added24,698$81K0.0%2025-Q4 stale (2 quarters behind)
Scientech Research LLC new15,510$51K0.0%2025-Q4 stale (2 quarters behind)
Global Retirement Partners, LLC trimmed1,500$5K0.0%2025-Q4 stale (2 quarters behind)
BANK OF AMERICA CORP /DE/ trimmed1,035$3K0.0%2025-Q4 stale (2 quarters behind)
JPMORGAN CHASE & CO added324$1K0.0%2025-Q4 stale (2 quarters behind)
Trustees of Columbia University in the City of New York133,903$265K0.1%2025-Q3 stale (3 quarters behind)
TWO SIGMA SECURITIES, LLC new13,749$27K0.0%2025-Q3 stale (3 quarters behind)
DLK Investment Management, LLC10,333$20K0.0%2025-Q3 stale (3 quarters behind)
China Universal Asset Management Co., Ltd. trimmed2,138$4K0.0%2025-Q3 stale (3 quarters behind)
Mirae Asset Global Investments Co., Ltd. added472$9350.0%2025-Q3 stale (3 quarters behind)
GF FUND MANAGEMENT CO. LTD. trimmed227$4490.0%2025-Q3 stale (3 quarters behind)
GOLDMAN SACHS GROUP INC added63,539$95K0.0%2025-Q2 stale (4 quarters behind)
AQR CAPITAL MANAGEMENT LLC trimmed26,530$40K0.0%2025-Q2 stale (4 quarters behind)
OPPENHEIMER & CO INC new13,000$19K0.0%2025-Q2 stale (4 quarters behind)
Mariner, LLC trimmed11,780$18K0.0%2025-Q2 stale (4 quarters behind)
RAYMOND JAMES FINANCIAL INC10,746$16K0.0%2025-Q2 stale (4 quarters behind)
SIMPLEX TRADING, LLC new813$1K0.0%2025-Q2 stale (4 quarters behind)
Clark Wealth Partners199$2970.0%2025-Q2 stale (4 quarters behind)
True Wealth Design, LLC added67$1000.0%2025-Q2 stale (4 quarters behind)

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership