Who owns Pyxis Oncology (PYXS)
Which tracked institutional funds hold PYXS, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PYXS company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on PYXS is one-sided between 2026-Q1 and 2026-Q2: 17 added or opened and 0 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
PYXS’s largest tracked holder by dollar value, GordonMD Global Investments LP, sizes it at 14.6% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 14.6pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in PYXS divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 74 tracked filers holding PYXS, 34 increased or opened the position and 36 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in PYXS between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 1
- Woodline Partners LP$2M
Largest adds
- GordonMD Global Investments LP$24M
- Pfizer Inc$10M
- Laurion Capital Management LP$7M
- VANGUARD CAPITAL MANAGEMENT LLC$3M
- MARSHALL WACE, LLP$2M
- BlackRock, Inc.$1M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| GordonMD Global Investments LP added | 10,024,909 | $30M | 25.6% | 2026-Q2 |
| Pfizer Inc | 7,032,770 | $19M | 16.5% | 2026-Q2 |
| Laurion Capital Management LP trimmed | 4,900,888 | $15M | 12.5% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 2,075,997 | $6M | 5.3% | 2026-Q2 |
| Atle Fund Management AB added | 966,459 | $3M | 2.5% | 2026-Q2 |
| BlackRock, Inc. added | 867,934 | $3M | 2.2% | 2026-Q2 |
| Palo Alto Investors LP trimmed | 864,277 | $3M | 2.2% | 2026-Q2 |
| MARSHALL WACE, LLP added | 830,544 | $2M | 2.1% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 772,232 | $2M | 2.0% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC trimmed | 591,849 | $2M | 1.5% | 2026-Q2 |
| Woodline Partners LP new | 523,999 | $2M | 1.3% | 2026-Q2 |
| 683 Capital Management, LLC trimmed | 459,367 | $1M | 1.2% | 2026-Q2 |
| JACOBS LEVY EQUITY MANAGEMENT, INC trimmed | 428,606 | $1M | 1.1% | 2026-Q2 |
| Longaeva Partners L.P. trimmed | 353,582 | $1M | 0.9% | 2026-Q2 |
| Decheng Capital LLC | 326,810 | $984K | 0.8% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 302,986 | $912K | 0.8% | 2026-Q2 |
| JANE STREET GROUP, LLC trimmed | 290,090 | $873K | 0.7% | 2026-Q2 |
| STATE STREET CORP | 248,837 | $749K | 0.6% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 233,004 | $701K | 0.6% | 2026-Q2 |
| UBS Group AG trimmed | 155,217 | $467K | 0.4% | 2026-Q2 |
| Bank of New York Mellon Corp | 133,996 | $403K | 0.3% | 2026-Q2 |
| NORTHERN TRUST CORP added | 123,959 | $373K | 0.3% | 2026-Q2 |
| NewEdge Wealth, LLC | 116,006 | $349K | 0.3% | 2026-Q2 |
| XTX Topco Ltd trimmed | 110,939 | $334K | 0.3% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP added | 83,961 | $253K | 0.2% | 2026-Q2 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 81,260 | $245K | 0.2% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 80,464 | $242K | 0.2% | 2026-Q2 |
| STIFEL FINANCIAL CORP added | 70,437 | $212K | 0.2% | 2026-Q2 |
| Cable Car Capital, LP | 61,606 | $185K | 0.2% | 2026-Q2 |
| MYDA Advisors LLC new | 50,000 | $150K | 0.1% | 2026-Q2 |
| Qube Research & Technologies Ltd added | 49,932 | $150K | 0.1% | 2026-Q2 |
| UNIVERSITY OF CHICAGO | 48,731 | $147K | 0.1% | 2026-Q2 |
| CITADEL ADVISORS LLC trimmed | 47,317 | $142K | 0.1% | 2026-Q2 |
| Quadrature Capital Ltd trimmed | 47,067 | $142K | 0.1% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC trimmed | 45,900 | $138K | 0.1% | 2026-Q2 |
| Verdad Advisers, LP new | 44,899 | $135K | 0.1% | 2026-Q2 |
| LPL Financial LLC added | 43,554 | $131K | 0.1% | 2026-Q2 |
| COMMONWEALTH EQUITY SERVICES, LLC added | 42,455 | $128K | 0.1% | 2026-Q2 |
| J. Derek Lewis & Associates Inc. trimmed | 42,000 | $126K | 0.1% | 2026-Q2 |
| CITIGROUP INC added | 38,205 | $115K | 0.1% | 2026-Q2 |
| SIMPLEX TRADING, LLC added | 37,902 | $114K | 0.1% | 2026-Q2 |
| Point72 Asset Management, L.P. added | 37,092 | $112K | 0.1% | 2026-Q2 |
| Walleye Capital LLC trimmed | 36,778 | $111K | 0.1% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP added | 36,175 | $109K | 0.1% | 2026-Q2 |
| MORGAN STANLEY trimmed | 33,448 | $101K | 0.1% | 2026-Q2 |
| MACKENZIE FINANCIAL CORP new | 26,343 | $79K | 0.1% | 2026-Q2 |
| Cetera Investment Advisers trimmed | 25,000 | $75K | 0.1% | 2026-Q2 |
| Graham Capital Management, L.P. trimmed | 22,708 | $68K | 0.1% | 2026-Q2 |
| Vanguard Global Advisers, LLC | 21,242 | $64K | 0.1% | 2026-Q2 |
| OSAIC HOLDINGS, INC. added | 17,721 | $53K | 0.0% | 2026-Q2 |
| GROUP ONE TRADING LLC added | 16,480 | $50K | 0.0% | 2026-Q2 |
| FMR LLC added | 12,383 | $37K | 0.0% | 2026-Q2 |
| PACES FERRY WEALTH ADVISORS, LLC | 11,440 | $34K | 0.0% | 2026-Q2 |
| NewEdge Advisors, LLC | 10,250 | $31K | 0.0% | 2026-Q2 |
| China Universal Asset Management Co., Ltd. trimmed | 10,083 | $30K | 0.0% | 2026-Q2 |
| Tower Research Capital LLC (TRC) trimmed | 9,398 | $28K | 0.0% | 2026-Q2 |
| PNC Financial Services Group, Inc. | 6,500 | $20K | 0.0% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 5,545 | $16K | 0.0% | 2026-Q2 |
| HAGER INVESTMENT MANAGEMENT SERVICES, LLC | 5,000 | $15K | 0.0% | 2026-Q2 |
| BARCLAYS PLC trimmed | 4,669 | $14K | 0.0% | 2026-Q2 |
| Federation des caisses Desjardins du Quebec new | 4,500 | $14K | 0.0% | 2026-Q2 |
| FEDERATED HERMES, INC. trimmed | 2,962 | $9K | 0.0% | 2026-Q2 |
| Mirae Asset Global Investments Co., Ltd. trimmed | 2,833 | $9K | 0.0% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS added | 2,689 | $8K | 0.0% | 2026-Q2 |
| FIRST UNITED BANK & TRUST new | 2,500 | $7K | 0.0% | 2026-Q2 |
| GF FUND MANAGEMENT CO. LTD. trimmed | 1,226 | $4K | 0.0% | 2026-Q2 |
| NISA INVESTMENT ADVISORS, LLC | 961 | $3K | 0.0% | 2026-Q2 |
| Physician Wealth Advisors, Inc. | 943 | $3K | 0.0% | 2026-Q2 |
| SBI Securities Co., Ltd. added | 509 | $2K | 0.0% | 2026-Q2 |
| JONES FINANCIAL COMPANIES LLLP | 500 | $1K | 0.0% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN | 285 | $858 | 0.0% | 2026-Q2 |
| Cornerstone Financial Management LLC | 172 | $518 | 0.0% | 2026-Q2 |
| Caitong International Asset Management Co., Ltd added | 35 | $105 | 0.0% | 2026-Q2 |
| Arax Advisory Partners added | 14 | $42 | 0.0% | 2026-Q2 |
| ACADIAN ASSET MANAGEMENT LLC added | 144,256 | $209K | 0.2% | 2026-Q1 stale (1 quarter behind) |
| PANAGORA ASSET MANAGEMENT INC new | 69,424 | $101K | 0.1% | 2026-Q1 stale (1 quarter behind) |
| TORONTO DOMINION BANK trimmed | 50,000 | $73K | 0.1% | 2026-Q1 stale (1 quarter behind) |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 41,201 | $60K | 0.1% | 2026-Q1 stale (1 quarter behind) |
| VANGUARD GROUP INC added | 2,335,768 | $3M | 2.3% | 2025-Q4 stale (2 quarters behind) |
| ExodusPoint Capital Management, LP new | 317,769 | $365K | 0.3% | 2025-Q4 stale (2 quarters behind) |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO added | 6,575 | $147K | 0.1% | 2025-Q4 stale (2 quarters behind) |
| OMERS ADMINISTRATION Corp new | 67,000 | $77K | 0.1% | 2025-Q4 stale (2 quarters behind) |
| Velan Capital Investment Management LP trimmed | 40,000 | $46K | 0.0% | 2025-Q4 stale (2 quarters behind) |
| HRT FINANCIAL LP added | 39,649 | $45K | 0.0% | 2025-Q4 stale (2 quarters behind) |
| AMERICAN CENTURY COMPANIES INC added | 31,936 | $37K | 0.0% | 2025-Q4 stale (2 quarters behind) |
| Lighthouse Investment Partners, LLC new | 28,860 | $33K | 0.0% | 2025-Q4 stale (2 quarters behind) |
| TANG CAPITAL MANAGEMENT LLC | 2,500,000 | $6M | 4.7% | 2025-Q3 stale (3 quarters behind) |
| PERCEPTIVE ADVISORS LLC added | 1,178,307 | $3M | 2.2% | 2025-Q3 stale (3 quarters behind) |
| STEMPOINT CAPITAL LP trimmed | 689,538 | $2M | 1.3% | 2025-Q3 stale (3 quarters behind) |
| Driehaus Capital Management LLC new | 418,632 | $929K | 0.8% | 2025-Q3 stale (3 quarters behind) |
| SCHULHOFF & CO INC | 275,000 | $610K | 0.5% | 2025-Q3 stale (3 quarters behind) |
| PIER 88 INVESTMENT PARTNERS LLC trimmed | 151,730 | $337K | 0.3% | 2025-Q3 stale (3 quarters behind) |
| DIADEMA PARTNERS LP new | 150,000 | $333K | 0.3% | 2025-Q3 stale (3 quarters behind) |
| Persistent Asset Partners Ltd new | 34,632 | $77K | 0.1% | 2025-Q3 stale (3 quarters behind) |
| Cubist Systematic Strategies, LLC new | 33,061 | $73K | 0.1% | 2025-Q3 stale (3 quarters behind) |
| Point72 Asia (Singapore) Pte. Ltd. trimmed | 18,057 | $40K | 0.0% | 2025-Q3 stale (3 quarters behind) |
| PRUDENTIAL FINANCIAL INC new | 16,300 | $36K | 0.0% | 2025-Q3 stale (3 quarters behind) |
| Aberdeen Group plc | 913,045 | $1M | 0.9% | 2025-Q2 stale (4 quarters behind) |
| Y-Intercept (Hong Kong) Ltd new | 133,047 | $146K | 0.1% | 2025-Q2 stale (4 quarters behind) |
| Jain Global LLC new | 48,649 | $54K | 0.0% | 2025-Q2 stale (4 quarters behind) |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.