Who owns PVLA (PVLA)
Which tracked institutional funds hold PVLA, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PVLA company fundamentals →
Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on PVLA is one-sided between 2025-Q4 and 2026-Q1: 94 added or opened and 20 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
PVLA’s largest tracked holder by dollar value, SUVRETTA CAPITAL MANAGEMENT, LLC, sizes it at 3.9% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 3.9pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in PVLA divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 182 tracked filers holding PVLA, 132 increased or opened the position and 55 reduced or closed it; over the same quarter, open-market insider Form 4s were net purchases.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in PVLA between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 41
- VANGUARD CAPITAL MANAGEMENT LLC$59M
- FRONTIER CAPITAL MANAGEMENT CO LLC$47M
- PRIMECAP MANAGEMENT CO/CA/$24M
- Alyeska Investment Group, L.P.$22M
- EMERALD ADVISERS, LLC$20M
- First Turn Management, LLC$18M
Full exits 12
- VANGUARD GROUP INC$52M
- SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC$41M
- PERCEPTIVE ADVISORS LLC$28M
- Artia Global Partners LP$6M
- SUPERSTRING CAPITAL MANAGEMENT LP$3M
- Verition Fund Management LLC$1M
Largest adds
- SUVRETTA CAPITAL MANAGEMENT, LLC$50M
- PRICE T ROWE ASSOCIATES INC /MD/$50M
- First Light Asset Management, LLC$48M
- JENNISON ASSOCIATES LLC$39M
- Frazier Life Sciences Management, L.P.$34M
- BVF INC/IL$28M
Largest trims
- FRED ALGER MANAGEMENT, LLC$13M
- MORGAN STANLEY$7M
- SAMSARA BIOCAPITAL, LLC$6M
- BARCLAYS PLC$2M
- Mariner, LLC$665K
- ALLIANCEBERNSTEIN L.P.$648K
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| SUVRETTA CAPITAL MANAGEMENT, LLC added | 1,153,496 | $144M | 8.1% | 2026-Q1 |
| First Light Asset Management, LLC added | 980,758 | $122M | 6.9% | 2026-Q1 |
| BVF INC/IL added | 960,989 | $120M | 6.7% | 2026-Q1 |
| Frazier Life Sciences Management, L.P. added | 882,400 | $110M | 6.2% | 2026-Q1 |
| BlackRock, Inc. added | 686,853 | $86M | 4.8% | 2026-Q1 |
| JENNISON ASSOCIATES LLC added | 640,611 | $80M | 4.5% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 477,294 | $59M | 3.4% | 2026-Q1 |
| STATE STREET CORP added | 458,999 | $57M | 3.2% | 2026-Q1 |
| FEDERATED HERMES, INC. added | 433,015 | $54M | 3.0% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 402,564 | $50M | 2.8% | 2026-Q1 |
| FRONTIER CAPITAL MANAGEMENT CO LLC new | 374,035 | $47M | 2.6% | 2026-Q1 |
| Woodline Partners LP added | 317,517 | $40M | 2.2% | 2026-Q1 |
| Siren, L.L.C. added | 257,485 | $32M | 1.8% | 2026-Q1 |
| EVENTIDE ASSET MANAGEMENT, LLC added | 233,248 | $29M | 1.6% | 2026-Q1 |
| ALLIANCEBERNSTEIN L.P. trimmed | 262,835 | $28M | 1.5% | 2026-Q1 |
| FMR LLC trimmed | 215,719 | $27M | 1.5% | 2026-Q1 |
| MPM BIOIMPACT LLC added | 206,404 | $26M | 1.4% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 205,609 | $26M | 1.4% | 2026-Q1 |
| PRIMECAP MANAGEMENT CO/CA/ new | 195,030 | $24M | 1.4% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 194,179 | $24M | 1.4% | 2026-Q1 |
| Artisan Partners Limited Partnership trimmed | 193,796 | $24M | 1.4% | 2026-Q1 |
| Alyeska Investment Group, L.P. new | 179,922 | $22M | 1.3% | 2026-Q1 |
| EMERALD ADVISERS, LLC new | 161,500 | $20M | 1.1% | 2026-Q1 |
| First Turn Management, LLC new | 148,093 | $18M | 1.0% | 2026-Q1 |
| ORBIMED ADVISORS LLC new | 134,600 | $17M | 0.9% | 2026-Q1 |
| MORGAN STANLEY trimmed | 127,987 | $16M | 0.9% | 2026-Q1 |
| EMERALD MUTUAL FUND ADVISERS TRUST new | 105,820 | $13M | 0.7% | 2026-Q1 |
| UBS Group AG added | 104,537 | $13M | 0.7% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. trimmed | 96,726 | $12M | 0.7% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 93,646 | $12M | 0.7% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 90,858 | $11M | 0.6% | 2026-Q1 |
| Clio Asset Management LLC trimmed | 90,757 | $11M | 0.6% | 2026-Q1 |
| Apis Capital Advisors, LLC added | 89,000 | $11M | 0.6% | 2026-Q1 |
| Point72 Asset Management, L.P. added | 88,160 | $11M | 0.6% | 2026-Q1 |
| NEXTBio Capital Management LP | 82,686 | $10M | 0.6% | 2026-Q1 |
| Aberdeen Group plc added | 81,081 | $10M | 0.6% | 2026-Q1 |
| Avidity Partners Management LP added | 70,000 | $9M | 0.5% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 69,901 | $9M | 0.5% | 2026-Q1 |
| AWM Investment Company, Inc. | 69,416 | $9M | 0.5% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 64,783 | $8M | 0.5% | 2026-Q1 |
| Ikarian Capital, LLC trimmed | 64,626 | $8M | 0.5% | 2026-Q1 |
| NORTHERN TRUST CORP added | 64,371 | $8M | 0.5% | 2026-Q1 |
| SEVEN GRAND MANAGERS, LLC new | 60,000 | $7M | 0.4% | 2026-Q1 |
| Clearbridge Investments, LLC trimmed | 59,410 | $7M | 0.4% | 2026-Q1 |
| NEUBERGER BERMAN GROUP LLC added | 49,103 | $6M | 0.3% | 2026-Q1 |
| Invesco Ltd. trimmed | 48,527 | $6M | 0.3% | 2026-Q1 |
| Lisanti Capital Growth, LLC trimmed | 41,445 | $5M | 0.3% | 2026-Q1 |
| Ensign Peak Advisors, Inc new | 39,223 | $5M | 0.3% | 2026-Q1 |
| SAMSARA BIOCAPITAL, LLC trimmed | 38,432 | $5M | 0.3% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 37,972 | $5M | 0.3% | 2026-Q1 |
| Trexquant Investment LP new | 36,639 | $5M | 0.3% | 2026-Q1 |
| WCM INVESTMENT MANAGEMENT, LLC new | 39,964 | $4M | 0.2% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP added | 32,475 | $4M | 0.2% | 2026-Q1 |
| ROYCE & ASSOCIATES LP added | 31,507 | $4M | 0.2% | 2026-Q1 |
| Blue Owl Capital Holdings LP trimmed | 31,259 | $4M | 0.2% | 2026-Q1 |
| Informed Momentum Co LLC new | 29,328 | $4M | 0.2% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 27,781 | $3M | 0.2% | 2026-Q1 |
| Nicholas Investment Partners, LP new | 27,603 | $3M | 0.2% | 2026-Q1 |
| RAYMOND JAMES FINANCIAL INC added | 25,446 | $3M | 0.2% | 2026-Q1 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. new | 25,000 | $3M | 0.2% | 2026-Q1 |
| NOMURA HOLDINGS INC new | 24,008 | $3M | 0.2% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 22,970 | $3M | 0.2% | 2026-Q1 |
| TD Asset Management Inc new | 22,746 | $3M | 0.2% | 2026-Q1 |
| FRED ALGER MANAGEMENT, LLC trimmed | 21,236 | $3M | 0.1% | 2026-Q1 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 21,142 | $3M | 0.1% | 2026-Q1 |
| Nuveen, LLC added | 20,834 | $3M | 0.1% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 20,472 | $3M | 0.1% | 2026-Q1 |
| ExodusPoint Capital Management, LP new | 20,277 | $3M | 0.1% | 2026-Q1 |
| BlueCrest Capital Management Ltd new | 20,000 | $2M | 0.1% | 2026-Q1 |
| FIFTH THIRD BANCORP new | 19,947 | $2M | 0.1% | 2026-Q1 |
| Swiss National Bank added | 19,400 | $2M | 0.1% | 2026-Q1 |
| BOOTHBAY FUND MANAGEMENT, LLC trimmed | 18,962 | $2M | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 18,808 | $2M | 0.1% | 2026-Q1 |
| Bank of New York Mellon Corp added | 18,041 | $2M | 0.1% | 2026-Q1 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 17,970 | $2M | 0.1% | 2026-Q1 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE added | 17,907 | $2M | 0.1% | 2026-Q1 |
| SEI INVESTMENTS CO added | 16,663 | $2M | 0.1% | 2026-Q1 |
| Legato Capital Management LLC added | 16,023 | $2M | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC trimmed | 14,590 | $2M | 0.1% | 2026-Q1 |
| F/m Investments LLC new | 13,839 | $2M | 0.1% | 2026-Q1 |
| Russell Investments Group, Ltd. added | 13,527 | $2M | 0.1% | 2026-Q1 |
| Squarepoint Ops LLC new | 13,067 | $2M | 0.1% | 2026-Q1 |
| Cresset Asset Management, LLC added | 11,860 | $1M | 0.1% | 2026-Q1 |
| VICTORY CAPITAL MANAGEMENT INC trimmed | 11,403 | $1M | 0.1% | 2026-Q1 |
| ALPS ADVISORS INC added | 11,132 | $1M | 0.1% | 2026-Q1 |
| Calamos Advisors LLC new | 9,804 | $1M | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS added | 9,129 | $1M | 0.1% | 2026-Q1 |
| Quadrature Capital Ltd new | 8,232 | $1M | 0.1% | 2026-Q1 |
| VANGUARD GROUP INC added | 495,710 | $52M | 2.9% | 2025-Q4 stale |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC added | 389,420 | $41M | 2.3% | 2025-Q4 stale |
| PERCEPTIVE ADVISORS LLC trimmed | 266,287 | $28M | 1.6% | 2025-Q4 stale |
| Nantahala Capital Management, LLC | 250,062 | $16M | 0.9% | 2025-Q3 stale |
| ADAMS STREET PARTNERS LLC trimmed | 298,986 | $7M | 0.4% | 2025-Q2 stale |
| Artia Global Partners LP new | 59,200 | $6M | 0.3% | 2025-Q4 stale |
| Opaleye Management Inc. new | 172,357 | $5M | 0.3% | 2025-Q1 stale |
| SECTORAL ASSET MANAGEMENT INC trimmed | 49,115 | $3M | 0.2% | 2025-Q3 stale |
| SUPERSTRING CAPITAL MANAGEMENT LP new | 25,469 | $3M | 0.2% | 2025-Q4 stale |
| J. Goldman & Co LP trimmed | 40,692 | $3M | 0.1% | 2025-Q3 stale |
| Verition Fund Management LLC new | 11,932 | $1M | 0.1% | 2025-Q4 stale |
| Catalio Capital Management, LP trimmed | 10,452 | $1M | 0.1% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.