Who owns Protagonist Therapeutics (PTGX)
Which tracked institutional funds hold PTGX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PTGX company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on PTGX is one-sided between 2026-Q1 and 2026-Q2: 144 added or opened and 47 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
PTGX’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes PTGX more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in PTGX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 323 tracked filers holding PTGX, 187 increased or opened the position and 144 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in PTGX between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 19
- Jupiter Topco LLC$261M
- Stephens Investment Management Group LLC$35M
- NOMURA ASSET MANAGEMENT INTERNATIONAL INC.$17M
- Catalio Capital Management, LP$13M
- Eversept Partners, LP$7M
- CASTLEARK MANAGEMENT LLC$6M
Full exits 24
- JANUS HENDERSON GROUP PLC$305M
- CITADEL ADVISORS LLC$164M
- Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.$60M
- Rubric Capital Management LP$45M
- Vestal Point Capital, LP$34M
- ADAGE CAPITAL PARTNERS GP, L.L.C.$30M
Largest adds
- BlackRock, Inc.$385M
- FARALLON CAPITAL MANAGEMENT, L.L.C.$109M
- PRICE T ROWE ASSOCIATES INC /MD/$88M
- RTW INVESTMENTS, LP$87M
- STATE STREET CORP$79M
- VANGUARD PORTFOLIO MANAGEMENT LLC$78M
Largest trims
- UBS Group AG$129M
- MARSHALL WACE, LLP$53M
- DIMENSIONAL FUND ADVISORS LP$32M
- Holocene Advisors, LP$21M
- PANAGORA ASSET MANAGEMENT INC$12M
- SUSQUEHANNA INTERNATIONAL GROUP, LLP$11M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| BlackRock, Inc. added | 10,307,837 | $1.3B | 14.0% | 2026-Q2 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | 6,348,906 | $778M | 8.6% | 2026-Q2 |
| RTW INVESTMENTS, LP added | 5,061,175 | $620M | 6.9% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 3,629,298 | $445M | 4.9% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 3,416,781 | $419M | 4.7% | 2026-Q2 |
| UBS Group AG trimmed | 3,399,221 | $417M | 4.6% | 2026-Q2 |
| STATE STREET CORP added | 3,321,554 | $407M | 4.5% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 2,853,394 | $350M | 3.9% | 2026-Q2 |
| JOHNSON & JOHNSON | 2,449,183 | $300M | 3.3% | 2026-Q2 |
| Invesco Ltd. added | 2,340,667 | $287M | 3.2% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 2,149,662 | $264M | 2.9% | 2026-Q2 |
| Jupiter Topco LLC new | 2,129,780 | $261M | 2.9% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,741,209 | $213M | 2.4% | 2026-Q2 |
| Woodline Partners LP | 1,414,173 | $173M | 1.9% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 1,324,498 | $162M | 1.8% | 2026-Q2 |
| JENNISON ASSOCIATES LLC added | 1,151,681 | $141M | 1.6% | 2026-Q2 |
| PERCEPTIVE ADVISORS LLC trimmed | 981,879 | $120M | 1.3% | 2026-Q2 |
| ADAR1 Capital Management, LLC trimmed | 960,863 | $118M | 1.3% | 2026-Q2 |
| MORGAN STANLEY trimmed | 905,992 | $111M | 1.2% | 2026-Q2 |
| Alyeska Investment Group, L.P. added | 889,298 | $109M | 1.2% | 2026-Q2 |
| Hood River Capital Management LLC added | 882,738 | $108M | 1.2% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 812,852 | $100M | 1.1% | 2026-Q2 |
| Driehaus Capital Management LLC added | 731,053 | $90M | 1.0% | 2026-Q2 |
| Clearbridge Investments, LLC added | 725,335 | $89M | 1.0% | 2026-Q2 |
| FMR LLC added | 672,186 | $82M | 0.9% | 2026-Q2 |
| NORTHERN TRUST CORP added | 666,105 | $82M | 0.9% | 2026-Q2 |
| AMERICAN CENTURY COMPANIES INC added | 598,600 | $73M | 0.8% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 583,774 | $72M | 0.8% | 2026-Q2 |
| VOYA INVESTMENT MANAGEMENT LLC added | 571,618 | $70M | 0.8% | 2026-Q2 |
| Pictet Asset Management Holding SA trimmed | 567,990 | $70M | 0.8% | 2026-Q2 |
| FRANKLIN RESOURCES INC added | 520,032 | $64M | 0.7% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 437,747 | $54M | 0.6% | 2026-Q2 |
| PRINCIPAL FINANCIAL GROUP INC added | 385,262 | $47M | 0.5% | 2026-Q2 |
| Bank of New York Mellon Corp added | 358,300 | $44M | 0.5% | 2026-Q2 |
| NEUBERGER BERMAN GROUP LLC added | 302,427 | $37M | 0.4% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS added | 301,472 | $37M | 0.4% | 2026-Q2 |
| 683 Capital Management, LLC trimmed | 290,000 | $36M | 0.4% | 2026-Q2 |
| Nuveen, LLC added | 284,085 | $35M | 0.4% | 2026-Q2 |
| Stephens Investment Management Group LLC new | 281,832 | $35M | 0.4% | 2026-Q2 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. trimmed | 259,972 | $32M | 0.4% | 2026-Q2 |
| Eagle Health Investments LP added | 248,322 | $30M | 0.3% | 2026-Q2 |
| NEXTBio Capital Management LP trimmed | 219,333 | $27M | 0.3% | 2026-Q2 |
| SEGALL BRYANT & HAMILL, LLC trimmed | 214,724 | $26M | 0.3% | 2026-Q2 |
| SEB Asset Management AB trimmed | 209,963 | $26M | 0.3% | 2026-Q2 |
| Duquesne Family Office LLC added | 208,900 | $26M | 0.3% | 2026-Q2 |
| Public Sector Pension Investment Board trimmed | 207,688 | $25M | 0.3% | 2026-Q2 |
| CITIGROUP INC added | 198,668 | $24M | 0.3% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 183,098 | $23M | 0.3% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP trimmed | 178,152 | $22M | 0.2% | 2026-Q2 |
| Affinity Asset Advisors, LLC | 172,125 | $21M | 0.2% | 2026-Q2 |
| Fisher Asset Management, LLC trimmed | 170,524 | $21M | 0.2% | 2026-Q2 |
| Boxer Capital Management, LLC | 170,000 | $21M | 0.2% | 2026-Q2 |
| RAYMOND JAMES FINANCIAL INC trimmed | 168,270 | $21M | 0.2% | 2026-Q2 |
| NAN FUNG TRINITY (HK) LTD | 160,670 | $20M | 0.2% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC trimmed | 143,810 | $18M | 0.2% | 2026-Q2 |
| DEUTSCHE BANK AG\ added | 141,838 | $17M | 0.2% | 2026-Q2 |
| RHUMBLINE ADVISERS trimmed | 141,279 | $17M | 0.2% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. new | 141,081 | $17M | 0.2% | 2026-Q2 |
| TD Asset Management Inc trimmed | 134,950 | $17M | 0.2% | 2026-Q2 |
| KENNEDY CAPITAL MANAGEMENT LLC trimmed | 134,019 | $16M | 0.2% | 2026-Q2 |
| Legal & General Group Plc trimmed | 132,351 | $16M | 0.2% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 115,425 | $14M | 0.2% | 2026-Q2 |
| MARSHALL WACE, LLP trimmed | 109,017 | $13M | 0.1% | 2026-Q2 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed | 108,555 | $13M | 0.1% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 107,094 | $13M | 0.1% | 2026-Q2 |
| Catalio Capital Management, LP new | 106,799 | $13M | 0.1% | 2026-Q2 |
| Swiss National Bank added | 102,400 | $13M | 0.1% | 2026-Q2 |
| Universal- Beteiligungs- und Servicegesellschaft mbH trimmed | 102,002 | $13M | 0.1% | 2026-Q2 |
| Opaleye Management Inc. | 100,000 | $12M | 0.1% | 2026-Q2 |
| ASSETMARK, INC added | 98,687 | $12M | 0.1% | 2026-Q2 |
| SEI INVESTMENTS CO added | 92,749 | $11M | 0.1% | 2026-Q2 |
| ALGERT GLOBAL LLC added | 87,698 | $11M | 0.1% | 2026-Q2 |
| PRUDENTIAL FINANCIAL INC trimmed | 85,180 | $10M | 0.1% | 2026-Q2 |
| VICTORY CAPITAL MANAGEMENT INC added | 83,883 | $10M | 0.1% | 2026-Q2 |
| AXIOM INVESTORS LLC /DE trimmed | 81,683 | $10M | 0.1% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. added | 79,563 | $8M | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 71,944 | $9M | 0.1% | 2026-Q2 |
| SCHRODER INVESTMENT MANAGEMENT GROUP trimmed | 64,991 | $8M | 0.1% | 2026-Q2 |
| NORDEA INVESTMENT MANAGEMENT AB added | 64,964 | $8M | 0.1% | 2026-Q2 |
| Knott David M Jr | 63,000 | $8M | 0.1% | 2026-Q2 |
| Atika Capital Management LLC | 62,100 | $8M | 0.1% | 2026-Q2 |
| Moody Aldrich Partners LLC added | 59,601 | $7M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 58,961 | $7M | 0.1% | 2026-Q2 |
| Eversept Partners, LP added | 58,504 | $7M | 0.1% | 2026-Q2 |
| Twin Lakes Capital Management, LLC trimmed | 58,059 | $7M | 0.1% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 57,062 | $7M | 0.1% | 2026-Q2 |
| GREAT LAKES ADVISORS, LLC trimmed | 56,904 | $7M | 0.1% | 2026-Q2 |
| Creative Planning added | 56,185 | $7M | 0.1% | 2026-Q2 |
| Bellevue Group AG added | 55,682 | $7M | 0.1% | 2026-Q2 |
| FIRST TRUST ADVISORS LP trimmed | 54,865 | $7M | 0.1% | 2026-Q2 |
| KVP Capital Advisors, LP | 53,000 | $6M | 0.1% | 2026-Q2 |
| VANGUARD ASSET MANAGEMENT, Ltd added | 51,639 | $6M | 0.1% | 2026-Q2 |
| CASTLEARK MANAGEMENT LLC new | 50,570 | $6M | 0.1% | 2026-Q2 |
| Granahan Investment Management, LLC added | 49,809 | $6M | 0.1% | 2026-Q2 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO trimmed | 48,894 | $6M | 0.1% | 2026-Q2 |
| SILVERCREST ASSET MANAGEMENT GROUP LLC trimmed | 45,668 | $6M | 0.1% | 2026-Q2 |
| Seven Fleet Capital Management LP added | 45,400 | $6M | 0.1% | 2026-Q2 |
| Caption Management, LLC trimmed | 45,000 | $6M | 0.1% | 2026-Q2 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP added | 44,529 | $5M | 0.1% | 2026-Q2 |
| ORBIMED ADVISORS LLC | 42,100 | $5M | 0.1% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.