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Institutional Ownership · SEC Form 13F

Who owns PTGX (PTGX)


Which tracked institutional funds hold PTGX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PTGX company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

321
Institutional holders
77,759,125
Shares held (tracked funds)

How the tape is positioned

142 tracked funds added or opened PTGX while 55 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

PTGX’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 0.0pp gap the other way — the median holder sizes PTGX more heavily than its largest holder by dollar value does.

Book-share is each fund’s reported value in PTGX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 321 tracked filers holding PTGX, 167 increased or opened the position and 163 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in PTGX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 23

  • VANGUARD PORTFOLIO MANAGEMENT LLC$367M
  • VANGUARD CAPITAL MANAGEMENT LLC$296M
  • Hood River Capital Management LLC$87M
  • Rubric Capital Management LP$45M
  • VANGUARD FIDUCIARY TRUST CO$44M
  • Vestal Point Capital, LP$34M

Full exits 29

  • VANGUARD GROUP INC$467M
  • Commodore Capital LP$39M
  • Skandinaviska Enskilda Banken AB (publ)$18M
  • MPM BIOIMPACT LLC$17M
  • AIHC Capital Management Ltd$17M
  • Qube Research & Technologies Ltd$13M

Largest adds

  • UBS Group AG$304M
  • FARALLON CAPITAL MANAGEMENT LLC$133M
  • WELLINGTON MANAGEMENT GROUP LLP$101M
  • RTW INVESTMENTS, LP$91M
  • Invesco Ltd.$85M
  • JENNISON ASSOCIATES LLC$84M

Largest trims

  • Pacer Advisors, Inc.$306M
  • MARSHALL WACE, LLP$23M
  • Driehaus Capital Management LLC$20M
  • BARCLAYS PLC$15M
  • Hudson Bay Capital Management LP$9M
  • KENNEDY CAPITAL MANAGEMENT LLC$5M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
BlackRock, Inc. trimmed8,338,427$879M9.9%2026-Q1
FARALLON CAPITAL MANAGEMENT LLC added6,348,906$669M7.5%2026-Q1
UBS Group AG added5,177,796$546M6.1%2026-Q1
RTW INVESTMENTS, LP5,059,053$533M6.0%2026-Q1
WELLINGTON MANAGEMENT GROUP LLP added3,590,878$378M4.3%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new3,481,211$367M4.1%2026-Q1
STATE STREET CORP trimmed3,116,749$329M3.7%2026-Q1
JANUS HENDERSON GROUP PLC added2,891,527$305M3.4%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new2,805,896$296M3.3%2026-Q1
JOHNSON & JOHNSON2,449,183$258M2.9%2026-Q1
Invesco Ltd. added2,110,216$222M2.5%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added1,669,371$176M2.0%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ added1,665,497$176M2.0%2026-Q1
CITADEL ADVISORS LLC added1,551,900$164M1.8%2026-Q1
Woodline Partners LP added1,414,173$149M1.7%2026-Q1
BANK OF AMERICA CORP /DE/ added1,295,434$137M1.5%2026-Q1
PERCEPTIVE ADVISORS LLC trimmed1,230,879$130M1.5%2026-Q1
JENNISON ASSOCIATES LLC added1,072,011$113M1.3%2026-Q1
MORGAN STANLEY added1,018,222$107M1.2%2026-Q1
ADAR1 Capital Management, LLC trimmed994,119$105M1.2%2026-Q1
Hood River Capital Management LLC new829,285$87M1.0%2026-Q1
GOLDMAN SACHS GROUP INC trimmed778,945$82M0.9%2026-Q1
Driehaus Capital Management LLC trimmed720,928$76M0.9%2026-Q1
FMR LLC added661,228$70M0.8%2026-Q1
MARSHALL WACE, LLP trimmed628,075$66M0.7%2026-Q1
Clearbridge Investments, LLC added621,820$66M0.7%2026-Q1
Alyeska Investment Group, L.P. added593,197$63M0.7%2026-Q1
NORTHERN TRUST CORP added587,968$62M0.7%2026-Q1
Pictet Asset Management Holding SA added581,083$61M0.7%2026-Q1
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.571,825$60M0.7%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed552,956$58M0.7%2026-Q1
AMERICAN CENTURY COMPANIES INC added537,320$57M0.6%2026-Q1
DIMENSIONAL FUND ADVISORS LP added508,103$54M0.6%2026-Q1
VOYA INVESTMENT MANAGEMENT LLC added454,383$48M0.5%2026-Q1
Rubric Capital Management LP added427,998$45M0.5%2026-Q1
VANGUARD FIDUCIARY TRUST CO new412,730$44M0.5%2026-Q1
PRINCIPAL FINANCIAL GROUP INC added367,822$39M0.4%2026-Q1
683 Capital Management, LLC trimmed355,000$37M0.4%2026-Q1
Bank of New York Mellon Corp trimmed341,465$36M0.4%2026-Q1
Vestal Point Capital, LP new326,159$34M0.4%2026-Q1
BNP PARIBAS ASSET MANAGEMENT Holding S.A. trimmed306,037$32M0.4%2026-Q1
ADAGE CAPITAL PARTNERS GP, L.L.C. added282,436$30M0.3%2026-Q1
SEB Asset Management AB new232,416$24M0.3%2026-Q1
NEXTBio Capital Management LP229,619$24M0.3%2026-Q1
Public Sector Pension Investment Board added210,280$22M0.2%2026-Q1
Holocene Advisors, LP trimmed209,916$22M0.2%2026-Q1
SEGALL BRYANT & HAMILL, LLC added216,056$21M0.2%2026-Q1
BNP PARIBAS FINANCIAL MARKETS added194,530$21M0.2%2026-Q1
TD Asset Management Inc added183,700$19M0.2%2026-Q1
Eagle Health Investments LP added179,322$19M0.2%2026-Q1
Fisher Asset Management, LLC added173,971$18M0.2%2026-Q1
Affinity Asset Advisors, LLC172,125$18M0.2%2026-Q1
Boxer Capital Management, LLC170,000$18M0.2%2026-Q1
RAYMOND JAMES FINANCIAL INC trimmed177,361$18M0.2%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP added167,576$18M0.2%2026-Q1
JPMORGAN CHASE & CO added172,990$17M0.2%2026-Q1
LORD, ABBETT & CO. LLC trimmed163,459$17M0.2%2026-Q1
NAN FUNG TRINITY (HK) LTD trimmed160,670$17M0.2%2026-Q1
Duquesne Family Office LLC159,700$17M0.2%2026-Q1
CITIGROUP INC added158,711$17M0.2%2026-Q1
RHUMBLINE ADVISERS added157,413$17M0.2%2026-Q1
AMERIPRISE FINANCIAL INC trimmed145,690$15M0.2%2026-Q1
NEUBERGER BERMAN GROUP LLC added141,441$15M0.2%2026-Q1
FRANKLIN RESOURCES INC added137,871$15M0.2%2026-Q1
KENNEDY CAPITAL MANAGEMENT LLC trimmed137,099$14M0.2%2026-Q1
Legal & General Group Plc trimmed135,367$14M0.2%2026-Q1
Nuveen, LLC added127,914$13M0.2%2026-Q1
MANUFACTURERS LIFE INSURANCE COMPANY, THE added127,818$13M0.2%2026-Q1
DEUTSCHE BANK AG\ added125,451$13M0.1%2026-Q1
PANAGORA ASSET MANAGEMENT INC trimmed116,609$12M0.1%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added107,437$11M0.1%2026-Q1
Universal- Beteiligungs- und Servicegesellschaft mbH trimmed105,514$11M0.1%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. added101,299$11M0.1%2026-Q1
Opaleye Management Inc. trimmed100,000$11M0.1%2026-Q1
Swiss National Bank added98,900$10M0.1%2026-Q1
PRUDENTIAL FINANCIAL INC trimmed95,235$10M0.1%2026-Q1
SCHRODER INVESTMENT MANAGEMENT GROUP added100,166$10M0.1%2026-Q1
FIRST TRUST ADVISORS LP added87,858$9M0.1%2026-Q1
AXIOM INVESTORS LLC /DE trimmed85,475$9M0.1%2026-Q1
VICTORY CAPITAL MANAGEMENT INC added83,544$9M0.1%2026-Q1
SEI INVESTMENTS CO added83,197$9M0.1%2026-Q1
ALGERT GLOBAL LLC added78,470$8M0.1%2026-Q1
STEMPOINT CAPITAL LP added72,577$8M0.1%2026-Q1
GREAT LAKES ADVISORS, LLC trimmed71,043$7M0.1%2026-Q1
VANGUARD GROUP INC added5,346,407$467M5.2%2025-Q4 stale
BVF INC/IL trimmed2,560,916$170M1.9%2025-Q3 stale
Deep Track Capital, LP trimmed1,715,691$114M1.3%2025-Q3 stale
Lynx1 Capital Management LP trimmed700,014$47M0.5%2025-Q3 stale
Commodore Capital LP trimmed450,000$39M0.4%2025-Q4 stale
MANGROVE PARTNERS IM, LLC added478,413$32M0.4%2025-Q3 stale
Focus Partners Wealth added448,988$30M0.3%2025-Q3 stale
JUPITER ASSET MANAGEMENT LTD added405,644$22M0.3%2025-Q2 stale
Logos Global Management LP added300,000$20M0.2%2025-Q3 stale
Skandinaviska Enskilda Banken AB (publ) added205,574$18M0.2%2025-Q4 stale
MPM BIOIMPACT LLC new199,471$17M0.2%2025-Q4 stale
AIHC Capital Management Ltd new189,823$17M0.2%2025-Q4 stale
Qube Research & Technologies Ltd added153,876$13M0.2%2025-Q4 stale
SOROS FUND MANAGEMENT LLC new100,000$9M0.1%2025-Q4 stale
ExodusPoint Capital Management, LP added124,929$8M0.1%2025-Q3 stale
Soleus Capital Management, L.P. trimmed169,000$8M0.1%2025-Q1 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership