Who owns Prime Medicine (PRME)
Which tracked institutional funds hold PRME, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PRME company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
33 tracked funds added or opened PRME while 13 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
PRME’s largest tracked holder by dollar value, Alphabet Inc., sizes it at 0.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.1pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in PRME divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 177 tracked filers holding PRME, 85 increased or opened the position and 97 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in PRME between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 6
- Jump Financial, LLC$5M
- Point72 Asset Management, L.P.$2M
- MILLENNIUM MANAGEMENT LLC$2M
- Jain Global LLC$794K
- JUPITER ASSET MANAGEMENT LTD$773K
- PEAK6 LLC$768K
Full exits 6
- T. Rowe Price Investment Management, Inc.$19M
- Greenwich Wealth Management LLC$3M
- HRT FINANCIAL LP$2M
- Bollard Group LLC$1M
- HighTower Advisors, LLC$1M
- Elevate Capital Advisors, LLC$526K
Largest adds
- GOLDMAN SACHS GROUP INC$9M
- ARK Investment Management LLC$9M
- CITADEL ADVISORS LLC$6M
- STATE STREET CORP$6M
- BlackRock, Inc.$6M
- Alphabet Inc.$3M
Largest trims
- D. E. Shaw & Co., Inc.$2M
- RENAISSANCE TECHNOLOGIES LLC$2M
- AQR CAPITAL MANAGEMENT LLC$1M
- Amova Asset Management Americas, Inc.$1M
- Sumitomo Mitsui Trust Group, Inc.$1M
- EverSource Wealth Advisors, LLC$1M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Alphabet Inc. | 16,562,498 | $61M | 16.7% | 2026-Q2 |
| BlackRock, Inc. added | 9,602,041 | $35M | 9.7% | 2026-Q2 |
| ARK Investment Management LLC added | 8,348,746 | $31M | 8.4% | 2026-Q2 |
| STATE STREET CORP added | 7,576,460 | $28M | 7.6% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 4,522,640 | $17M | 4.6% | 2026-Q2 |
| BALYASNY ASSET MANAGEMENT L.P. trimmed | 3,969,082 | $15M | 4.0% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 3,430,518 | $13M | 3.5% | 2026-Q2 |
| Casdin Capital, LLC | 3,167,175 | $12M | 3.2% | 2026-Q2 |
| Woodline Partners LP added | 3,003,904 | $11M | 3.0% | 2026-Q2 |
| UBS Group AG trimmed | 2,794,689 | $10M | 2.8% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC trimmed | 2,712,446 | $10M | 2.7% | 2026-Q2 |
| Sumitomo Mitsui Trust Group, Inc. trimmed | 2,412,984 | $9M | 2.4% | 2026-Q2 |
| Amova Asset Management Americas, Inc. trimmed | 2,407,018 | $9M | 2.4% | 2026-Q2 |
| CITADEL ADVISORS LLC added | 2,054,543 | $8M | 2.1% | 2026-Q2 |
| ADAR1 Capital Management, LLC added | 1,997,552 | $7M | 2.0% | 2026-Q2 |
| FMR LLC trimmed | 1,761,884 | $7M | 1.8% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP trimmed | 1,524,511 | $6M | 1.5% | 2026-Q2 |
| Redmile Group, LLC trimmed | 1,389,632 | $5M | 1.4% | 2026-Q2 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | 1,240,843 | $5M | 1.3% | 2026-Q2 |
| Jump Financial, LLC added | 1,240,429 | $5M | 1.3% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 981,335 | $4M | 1.0% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 961,826 | $4M | 1.0% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 927,538 | $3M | 0.9% | 2026-Q2 |
| NORTHERN TRUST CORP added | 912,597 | $3M | 0.9% | 2026-Q2 |
| JPMORGAN CHASE & CO trimmed | 810,095 | $3M | 0.8% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 764,633 | $3M | 0.8% | 2026-Q2 |
| MORGAN STANLEY added | 708,963 | $3M | 0.7% | 2026-Q2 |
| Alessandra Capital Management, LLC added | 666,603 | $2M | 0.7% | 2026-Q2 |
| D. E. Shaw & Co., Inc. trimmed | 648,940 | $2M | 0.7% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 648,479 | $2M | 0.7% | 2026-Q2 |
| Point72 Asset Management, L.P. trimmed | 533,553 | $2M | 0.5% | 2026-Q2 |
| MOORE CAPITAL MANAGEMENT, LP | 500,000 | $2M | 0.5% | 2026-Q2 |
| CHELSEA COUNSEL CO added | 449,060 | $2M | 0.5% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC added | 427,097 | $2M | 0.4% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP added | 304,678 | $1M | 0.3% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP added | 304,444 | $1M | 0.3% | 2026-Q2 |
| Nuveen, LLC | 275,931 | $1M | 0.3% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN trimmed | 251,747 | $929K | 0.3% | 2026-Q2 |
| Bank of New York Mellon Corp trimmed | 246,344 | $909K | 0.2% | 2026-Q2 |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd added | 225,799 | $833K | 0.2% | 2026-Q2 |
| MARSHALL WACE, LLP added | 216,841 | $800K | 0.2% | 2026-Q2 |
| XTX Topco Ltd added | 215,708 | $796K | 0.2% | 2026-Q2 |
| Jain Global LLC added | 215,218 | $794K | 0.2% | 2026-Q2 |
| JUPITER ASSET MANAGEMENT LTD new | 209,490 | $773K | 0.2% | 2026-Q2 |
| Swiss National Bank added | 208,300 | $769K | 0.2% | 2026-Q2 |
| PEAK6 LLC added | 208,057 | $768K | 0.2% | 2026-Q2 |
| CITIGROUP INC added | 195,664 | $722K | 0.2% | 2026-Q2 |
| Green Alpha Advisors, LLC trimmed | 185,023 | $683K | 0.2% | 2026-Q2 |
| Keystone Financial Group added | 166,510 | $614K | 0.2% | 2026-Q2 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 162,338 | $600K | 0.2% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 162,325 | $599K | 0.2% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 157,049 | $580K | 0.2% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. added | 150,300 | $523K | 0.1% | 2026-Q2 |
| Rafferty Asset Management, LLC trimmed | 145,275 | $536K | 0.1% | 2026-Q2 |
| Invesco Ltd. added | 140,308 | $518K | 0.1% | 2026-Q2 |
| Concurrent Investment Advisors, LLC added | 131,722 | $486K | 0.1% | 2026-Q2 |
| ExodusPoint Capital Management, LP added | 118,464 | $437K | 0.1% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 117,998 | $435K | 0.1% | 2026-Q2 |
| Virtus Investment Advisers, LLC added | 117,909 | $435K | 0.1% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 117,412 | $433K | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 116,754 | $431K | 0.1% | 2026-Q2 |
| FIL Ltd | 115,206 | $425K | 0.1% | 2026-Q2 |
| DEUTSCHE BANK AG\ trimmed | 114,472 | $422K | 0.1% | 2026-Q2 |
| Steward Partners Investment Advisory, LLC trimmed | 108,290 | $400K | 0.1% | 2026-Q2 |
| Palumbo Wealth Management LLC added | 103,801 | $383K | 0.1% | 2026-Q2 |
| MILESTONE ASSET MANAGEMENT, LLC new | 100,035 | $369K | 0.1% | 2026-Q2 |
| TD Asset Management Inc | 94,148 | $347K | 0.1% | 2026-Q2 |
| LPL Financial LLC added | 92,174 | $340K | 0.1% | 2026-Q2 |
| Rockefeller Capital Management L.P. trimmed | 90,735 | $335K | 0.1% | 2026-Q2 |
| BARCLAYS PLC added | 88,058 | $325K | 0.1% | 2026-Q2 |
| Squarepoint Ops LLC trimmed | 88,029 | $325K | 0.1% | 2026-Q2 |
| COMMONWEALTH EQUITY SERVICES, LLC added | 87,310 | $322K | 0.1% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 85,300 | $315K | 0.1% | 2026-Q2 |
| LOS ANGELES CAPITAL MANAGEMENT LLC added | 82,305 | $304K | 0.1% | 2026-Q2 |
| PROFUND ADVISORS LLC trimmed | 72,624 | $268K | 0.1% | 2026-Q2 |
| Legal & General Group Plc | 66,444 | $245K | 0.1% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS added | 66,101 | $244K | 0.1% | 2026-Q2 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC trimmed | 64,800 | $239K | 0.1% | 2026-Q2 |
| Jupiter Topco LLC new | 60,900 | $224K | 0.1% | 2026-Q2 |
| Engineers Gate Manager LP trimmed | 59,133 | $218K | 0.1% | 2026-Q2 |
| VANGUARD ASSET MANAGEMENT, Ltd | 59,021 | $218K | 0.1% | 2026-Q2 |
| &PARTNERS trimmed | 57,460 | $211K | 0.1% | 2026-Q2 |
| MetLife Investment Management, LLC added | 56,192 | $207K | 0.1% | 2026-Q2 |
| Russell Investments Group, Ltd. trimmed | 50,994 | $188K | 0.1% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC added | 49,941 | $184K | 0.1% | 2026-Q2 |
| Mutual Advisors, LLC trimmed | 45,000 | $166K | 0.0% | 2026-Q2 |
| Vanguard Global Advisers, LLC | 44,269 | $163K | 0.0% | 2026-Q2 |
| Quadrature Capital Ltd trimmed | 43,663 | $161K | 0.0% | 2026-Q2 |
| IvyRock Asset Management (HK) Ltd | 41,800 | $154K | 0.0% | 2026-Q2 |
| JONES FINANCIAL COMPANIES LLLP added | 40,867 | $140K | 0.0% | 2026-Q2 |
| Corient Private Wealth LP trimmed | 38,881 | $143K | 0.0% | 2026-Q2 |
| State of New Jersey Common Pension Fund D added | 33,569 | $124K | 0.0% | 2026-Q2 |
| Crestwood Advisors Group, LLC trimmed | 32,041 | $118K | 0.0% | 2026-Q2 |
| Police & Firemen's Retirement System of New Jersey | 30,751 | $113K | 0.0% | 2026-Q2 |
| OPPENHEIMER & CO INC trimmed | 29,650 | $109K | 0.0% | 2026-Q2 |
| RAYMOND JAMES FINANCIAL INC added | 29,184 | $108K | 0.0% | 2026-Q2 |
| SEI INVESTMENTS CO | 29,183 | $108K | 0.0% | 2026-Q2 |
| China Universal Asset Management Co., Ltd. trimmed | 28,745 | $106K | 0.0% | 2026-Q2 |
| ARIZONA STATE RETIREMENT SYSTEM added | 28,646 | $106K | 0.0% | 2026-Q2 |
| ENVESTNET ASSET MANAGEMENT INC trimmed | 28,278 | $104K | 0.0% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.