Skip to main content
Institutional Ownership · SEC Form 13F

Who owns Prime Medicine (PRME)


Which tracked institutional funds hold PRME, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PRME company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

177
Institutional holders
100M
Shares held (tracked funds)
55.3%
Of shares outstanding

How the tape is positioned

33 tracked funds added or opened PRME while 13 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

PRME’s largest tracked holder by dollar value, Alphabet Inc., sizes it at 0.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.1pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in PRME divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 177 tracked filers holding PRME, 85 increased or opened the position and 97 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in PRME between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 6

  • Jump Financial, LLC$5M
  • Point72 Asset Management, L.P.$2M
  • MILLENNIUM MANAGEMENT LLC$2M
  • Jain Global LLC$794K
  • JUPITER ASSET MANAGEMENT LTD$773K
  • PEAK6 LLC$768K

Full exits 6

  • T. Rowe Price Investment Management, Inc.$19M
  • Greenwich Wealth Management LLC$3M
  • HRT FINANCIAL LP$2M
  • Bollard Group LLC$1M
  • HighTower Advisors, LLC$1M
  • Elevate Capital Advisors, LLC$526K

Largest adds

  • GOLDMAN SACHS GROUP INC$9M
  • ARK Investment Management LLC$9M
  • CITADEL ADVISORS LLC$6M
  • STATE STREET CORP$6M
  • BlackRock, Inc.$6M
  • Alphabet Inc.$3M

Largest trims

  • D. E. Shaw & Co., Inc.$2M
  • RENAISSANCE TECHNOLOGIES LLC$2M
  • AQR CAPITAL MANAGEMENT LLC$1M
  • Amova Asset Management Americas, Inc.$1M
  • Sumitomo Mitsui Trust Group, Inc.$1M
  • EverSource Wealth Advisors, LLC$1M

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
Alphabet Inc.16,562,498$61M16.7%2026-Q2
BlackRock, Inc. added9,602,041$35M9.7%2026-Q2
ARK Investment Management LLC added8,348,746$31M8.4%2026-Q2
STATE STREET CORP added7,576,460$28M7.6%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added4,522,640$17M4.6%2026-Q2
BALYASNY ASSET MANAGEMENT L.P. trimmed3,969,082$15M4.0%2026-Q2
GOLDMAN SACHS GROUP INC added3,430,518$13M3.5%2026-Q2
Casdin Capital, LLC3,167,175$12M3.2%2026-Q2
Woodline Partners LP added3,003,904$11M3.0%2026-Q2
UBS Group AG trimmed2,794,689$10M2.8%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC trimmed2,712,446$10M2.7%2026-Q2
Sumitomo Mitsui Trust Group, Inc. trimmed2,412,984$9M2.4%2026-Q2
Amova Asset Management Americas, Inc. trimmed2,407,018$9M2.4%2026-Q2
CITADEL ADVISORS LLC added2,054,543$8M2.1%2026-Q2
ADAR1 Capital Management, LLC added1,997,552$7M2.0%2026-Q2
FMR LLC trimmed1,761,884$7M1.8%2026-Q2
TWO SIGMA INVESTMENTS, LP trimmed1,524,511$6M1.5%2026-Q2
Redmile Group, LLC trimmed1,389,632$5M1.4%2026-Q2
FARALLON CAPITAL MANAGEMENT, L.L.C.1,240,843$5M1.3%2026-Q2
Jump Financial, LLC added1,240,429$5M1.3%2026-Q2
BANK OF AMERICA CORP /DE/ added981,335$4M1.0%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC added961,826$4M1.0%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added927,538$3M0.9%2026-Q2
NORTHERN TRUST CORP added912,597$3M0.9%2026-Q2
JPMORGAN CHASE & CO trimmed810,095$3M0.8%2026-Q2
VANGUARD FIDUCIARY TRUST CO added764,633$3M0.8%2026-Q2
MORGAN STANLEY added708,963$3M0.7%2026-Q2
Alessandra Capital Management, LLC added666,603$2M0.7%2026-Q2
D. E. Shaw & Co., Inc. trimmed648,940$2M0.7%2026-Q2
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed648,479$2M0.7%2026-Q2
Point72 Asset Management, L.P. trimmed533,553$2M0.5%2026-Q2
MOORE CAPITAL MANAGEMENT, LP500,000$2M0.5%2026-Q2
CHELSEA COUNSEL CO added449,060$2M0.5%2026-Q2
MILLENNIUM MANAGEMENT LLC added427,097$2M0.4%2026-Q2
DIMENSIONAL FUND ADVISORS LP added304,678$1M0.3%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP added304,444$1M0.3%2026-Q2
Nuveen, LLC275,931$1M0.3%2026-Q2
WELLS FARGO & COMPANY/MN trimmed251,747$929K0.3%2026-Q2
Bank of New York Mellon Corp trimmed246,344$909K0.2%2026-Q2
IQ EQ FUND MANAGEMENT (IRELAND) Ltd added225,799$833K0.2%2026-Q2
MARSHALL WACE, LLP added216,841$800K0.2%2026-Q2
XTX Topco Ltd added215,708$796K0.2%2026-Q2
Jain Global LLC added215,218$794K0.2%2026-Q2
JUPITER ASSET MANAGEMENT LTD new209,490$773K0.2%2026-Q2
Swiss National Bank added208,300$769K0.2%2026-Q2
PEAK6 LLC added208,057$768K0.2%2026-Q2
CITIGROUP INC added195,664$722K0.2%2026-Q2
Green Alpha Advisors, LLC trimmed185,023$683K0.2%2026-Q2
Keystone Financial Group added166,510$614K0.2%2026-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added162,338$600K0.2%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ added162,325$599K0.2%2026-Q2
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added157,049$580K0.2%2026-Q2
ALLIANCEBERNSTEIN L.P. added150,300$523K0.1%2026-Q2
Rafferty Asset Management, LLC trimmed145,275$536K0.1%2026-Q2
Invesco Ltd. added140,308$518K0.1%2026-Q2
Concurrent Investment Advisors, LLC added131,722$486K0.1%2026-Q2
ExodusPoint Capital Management, LP added118,464$437K0.1%2026-Q2
AQR CAPITAL MANAGEMENT LLC trimmed117,998$435K0.1%2026-Q2
Virtus Investment Advisers, LLC added117,909$435K0.1%2026-Q2
RENAISSANCE TECHNOLOGIES LLC trimmed117,412$433K0.1%2026-Q2
RHUMBLINE ADVISERS added116,754$431K0.1%2026-Q2
FIL Ltd115,206$425K0.1%2026-Q2
DEUTSCHE BANK AG\ trimmed114,472$422K0.1%2026-Q2
Steward Partners Investment Advisory, LLC trimmed108,290$400K0.1%2026-Q2
Palumbo Wealth Management LLC added103,801$383K0.1%2026-Q2
MILESTONE ASSET MANAGEMENT, LLC new100,035$369K0.1%2026-Q2
TD Asset Management Inc94,148$347K0.1%2026-Q2
LPL Financial LLC added92,174$340K0.1%2026-Q2
Rockefeller Capital Management L.P. trimmed90,735$335K0.1%2026-Q2
BARCLAYS PLC added88,058$325K0.1%2026-Q2
Squarepoint Ops LLC trimmed88,029$325K0.1%2026-Q2
COMMONWEALTH EQUITY SERVICES, LLC added87,310$322K0.1%2026-Q2
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC85,300$315K0.1%2026-Q2
LOS ANGELES CAPITAL MANAGEMENT LLC added82,305$304K0.1%2026-Q2
PROFUND ADVISORS LLC trimmed72,624$268K0.1%2026-Q2
Legal & General Group Plc66,444$245K0.1%2026-Q2
BNP PARIBAS FINANCIAL MARKETS added66,101$244K0.1%2026-Q2
BRIDGEWAY CAPITAL MANAGEMENT, LLC trimmed64,800$239K0.1%2026-Q2
Jupiter Topco LLC new60,900$224K0.1%2026-Q2
Engineers Gate Manager LP trimmed59,133$218K0.1%2026-Q2
VANGUARD ASSET MANAGEMENT, Ltd59,021$218K0.1%2026-Q2
&PARTNERS trimmed57,460$211K0.1%2026-Q2
MetLife Investment Management, LLC added56,192$207K0.1%2026-Q2
Russell Investments Group, Ltd. trimmed50,994$188K0.1%2026-Q2
AMERIPRISE FINANCIAL INC added49,941$184K0.1%2026-Q2
Mutual Advisors, LLC trimmed45,000$166K0.0%2026-Q2
Vanguard Global Advisers, LLC44,269$163K0.0%2026-Q2
Quadrature Capital Ltd trimmed43,663$161K0.0%2026-Q2
IvyRock Asset Management (HK) Ltd41,800$154K0.0%2026-Q2
JONES FINANCIAL COMPANIES LLLP added40,867$140K0.0%2026-Q2
Corient Private Wealth LP trimmed38,881$143K0.0%2026-Q2
State of New Jersey Common Pension Fund D added33,569$124K0.0%2026-Q2
Crestwood Advisors Group, LLC trimmed32,041$118K0.0%2026-Q2
Police & Firemen's Retirement System of New Jersey30,751$113K0.0%2026-Q2
OPPENHEIMER & CO INC trimmed29,650$109K0.0%2026-Q2
RAYMOND JAMES FINANCIAL INC added29,184$108K0.0%2026-Q2
SEI INVESTMENTS CO29,183$108K0.0%2026-Q2
China Universal Asset Management Co., Ltd. trimmed28,745$106K0.0%2026-Q2
ARIZONA STATE RETIREMENT SYSTEM added28,646$106K0.0%2026-Q2
ENVESTNET ASSET MANAGEMENT INC trimmed28,278$104K0.0%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership