Who owns PLRX (PLRX)
Which tracked institutional funds hold PLRX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PLRX company fundamentals →
Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
10 tracked funds added or opened PLRX while 10 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
PLRX’s largest tracked holder by dollar value, TANG CAPITAL MANAGEMENT LLC, sizes it at 0.4% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.4pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in PLRX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 91 tracked filers holding PLRX, 40 increased or opened the position and 46 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in PLRX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 2
- VANGUARD CAPITAL MANAGEMENT LLC$3M
- DAFNA Capital Management LLC$614K
Full exits 3
- VANGUARD GROUP INC$3M
- TWO SIGMA ADVISERS, LP$2M
- DekaBank Deutsche Girozentrale$633K
Largest adds
- ADAR1 Capital Management, LLC$3M
- TWO SIGMA INVESTMENTS, LP$2M
- RENAISSANCE TECHNOLOGIES LLC$1M
- MILLENNIUM MANAGEMENT LLC$989K
- CITADEL ADVISORS LLC$914K
- Peapod Lane Capital LLC$508K
Largest trims
- Redmile Group, LLC$999K
- Centiva Capital, LP$675K
- JPMORGAN CHASE & CO$467K
- BANK OF AMERICA CORP /DE/$424K
- Woodline Partners LP$372K
- JANE STREET GROUP, LLC$348K
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 6,143,132 | $8M | 8.7% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 3,226,599 | $4M | 4.6% | 2026-Q1 |
| Blue Owl Capital Holdings LP | 2,969,199 | $4M | 4.2% | 2026-Q1 |
| ADAR1 Capital Management, LLC added | 2,585,126 | $3M | 3.7% | 2026-Q1 |
| ACADIAN ASSET MANAGEMENT LLC added | 2,416,508 | $3M | 3.4% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 2,343,101 | $3M | 3.3% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP added | 2,253,138 | $3M | 3.2% | 2026-Q1 |
| Monaco Asset Management SAM | 1,938,747 | $2M | 2.8% | 2026-Q1 |
| RENAISSANCE TECHNOLOGIES LLC added | 1,852,842 | $2M | 2.6% | 2026-Q1 |
| Prosight Management, LP added | 1,667,600 | $2M | 2.4% | 2026-Q1 |
| Woodline Partners LP trimmed | 1,666,830 | $2M | 2.4% | 2026-Q1 |
| BML Capital Management, LLC | 1,546,137 | $2M | 2.2% | 2026-Q1 |
| Peapod Lane Capital LLC added | 1,288,578 | $2M | 1.8% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 1,180,518 | $1M | 1.7% | 2026-Q1 |
| BlackRock, Inc. added | 1,096,430 | $1M | 1.6% | 2026-Q1 |
| UBS Group AG trimmed | 1,057,954 | $1M | 1.5% | 2026-Q1 |
| MARSHALL WACE, LLP trimmed | 910,174 | $1M | 1.3% | 2026-Q1 |
| Eversept Partners, LP added | 891,425 | $1M | 1.3% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 861,823 | $1M | 1.1% | 2026-Q1 |
| Redmile Group, LLC trimmed | 772,126 | $973K | 1.1% | 2026-Q1 |
| JACOBS LEVY EQUITY MANAGEMENT, INC added | 718,543 | $905K | 1.0% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 596,837 | $752K | 0.8% | 2026-Q1 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC added | 553,630 | $698K | 0.8% | 2026-Q1 |
| BESSEMER GROUP INC | 532,079 | $670K | 0.8% | 2026-Q1 |
| Connor, Clark & Lunn Investment Management Ltd. added | 517,453 | $652K | 0.7% | 2026-Q1 |
| MORGAN STANLEY trimmed | 505,739 | $637K | 0.7% | 2026-Q1 |
| XTX Topco Ltd trimmed | 500,838 | $631K | 0.7% | 2026-Q1 |
| DAFNA Capital Management LLC new | 487,000 | $614K | 0.7% | 2026-Q1 |
| Centiva Capital, LP trimmed | 432,525 | $545K | 0.6% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC trimmed | 417,274 | $526K | 0.6% | 2026-Q1 |
| Laurion Capital Management LP added | 412,796 | $520K | 0.6% | 2026-Q1 |
| GSA CAPITAL PARTNERS LLP trimmed | 402,092 | $507K | 0.6% | 2026-Q1 |
| JANE STREET GROUP, LLC trimmed | 356,794 | $450K | 0.5% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ trimmed | 352,708 | $444K | 0.5% | 2026-Q1 |
| TORNO CAPITAL, LLC added | 350,000 | $441K | 0.5% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 339,540 | $428K | 0.5% | 2026-Q1 |
| SEI INVESTMENTS CO | 297,291 | $375K | 0.4% | 2026-Q1 |
| ArrowMark Colorado Holdings LLC | 281,189 | $354K | 0.4% | 2026-Q1 |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P added | 275,000 | $346K | 0.4% | 2026-Q1 |
| STATE STREET CORP | 253,418 | $319K | 0.4% | 2026-Q1 |
| Rangeley Capital, LLC | 225,000 | $284K | 0.3% | 2026-Q1 |
| Stonepine Capital Management, LLC trimmed | 224,650 | $283K | 0.3% | 2026-Q1 |
| HighMark Wealth Management LLC trimmed | 166,224 | $209K | 0.2% | 2026-Q1 |
| Squarepoint Ops LLC added | 163,215 | $206K | 0.2% | 2026-Q1 |
| NORTHERN TRUST CORP added | 154,176 | $194K | 0.2% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 153,810 | $194K | 0.2% | 2026-Q1 |
| Invesco Ltd. added | 115,218 | $145K | 0.2% | 2026-Q1 |
| OSAIC HOLDINGS, INC. trimmed | 114,924 | $145K | 0.2% | 2026-Q1 |
| Hennion & Walsh Asset Management, Inc. trimmed | 106,705 | $134K | 0.2% | 2026-Q1 |
| Bond & Devick Financial Network, Inc. | 100,160 | $126K | 0.1% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP trimmed | 99,773 | $125K | 0.1% | 2026-Q1 |
| Verdad Advisers, LP new | 98,320 | $124K | 0.1% | 2026-Q1 |
| ALGERT GLOBAL LLC | 84,452 | $106K | 0.1% | 2026-Q1 |
| FEDERATED HERMES, INC. added | 62,651 | $79K | 0.1% | 2026-Q1 |
| AMERIPRISE FINANCIAL INC trimmed | 55,129 | $69K | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 52,956 | $67K | 0.1% | 2026-Q1 |
| Quadrature Capital Ltd trimmed | 50,981 | $64K | 0.1% | 2026-Q1 |
| SIMPLEX TRADING, LLC added | 48,054 | $61K | 0.1% | 2026-Q1 |
| Point72 Asset Management, L.P. added | 47,054 | $59K | 0.1% | 2026-Q1 |
| TUDOR INVESTMENT CORP ET AL | 29,729 | $37K | 0.0% | 2026-Q1 |
| Deep Track Capital, LP trimmed | 3,947,807 | $5M | 5.2% | 2025-Q2 stale |
| Cormorant Asset Management, LP added | 3,000,000 | $4M | 4.6% | 2025-Q1 stale |
| VANGUARD GROUP INC added | 2,818,241 | $3M | 3.9% | 2025-Q4 stale |
| Madison Avenue Partners, LP added | 2,230,012 | $3M | 2.9% | 2025-Q2 stale |
| TRV GP IV, LLC | 2,132,867 | $2M | 2.8% | 2025-Q2 stale |
| TWO SIGMA ADVISERS, LP added | 1,245,600 | $2M | 1.7% | 2025-Q4 stale |
| GREAT POINT PARTNERS LLC | 850,000 | $1M | 1.4% | 2025-Q3 stale |
| Rock Springs Capital Management LP added | 589,996 | $796K | 0.9% | 2025-Q1 stale |
| Nuveen, LLC new | 233,585 | $635K | 0.7% | 2025-Q1 stale |
| DekaBank Deutsche Girozentrale | 40,000 | $633K | 0.7% | 2025-Q4 stale |
| Allostery Investments LP new | 441,686 | $596K | 0.7% | 2025-Q1 stale |
| Graham Capital Management, L.P. added | 333,421 | $450K | 0.5% | 2025-Q1 stale |
| Verition Fund Management LLC added | 262,698 | $355K | 0.4% | 2025-Q1 stale |
| Seven Fleet Capital Management LP new | 276,500 | $337K | 0.4% | 2025-Q4 stale |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed | 251,365 | $292K | 0.3% | 2025-Q2 stale |
| CW Advisors, LLC trimmed | 199,920 | $232K | 0.3% | 2025-Q2 stale |
| Voleon Capital Management LP added | 149,041 | $221K | 0.2% | 2025-Q3 stale |
| UBS AM, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS LLC added | 154,906 | $209K | 0.2% | 2025-Q1 stale |
| RICE HALL JAMES & ASSOCIATES, LLC added | 147,705 | $180K | 0.2% | 2025-Q4 stale |
| DIADEMA PARTNERS LP new | 144,914 | $177K | 0.2% | 2025-Q4 stale |
| AMERICAN CENTURY COMPANIES INC added | 110,093 | $149K | 0.2% | 2025-Q1 stale |
| HighVista Strategies LLC added | 109,938 | $148K | 0.2% | 2025-Q1 stale |
| Swiss National Bank | 95,700 | $129K | 0.1% | 2025-Q1 stale |
| KOTLER KEVIN new | 93,000 | $113K | 0.1% | 2025-Q4 stale |
| INTECH INVESTMENT MANAGEMENT LLC added | 79,004 | $107K | 0.1% | 2025-Q1 stale |
| PRICE T ROWE ASSOCIATES INC /MD/ trimmed | 83,868 | $98K | 0.1% | 2025-Q2 stale |
| Catalyst Funds Management Pty Ltd added | 59,539 | $88K | 0.1% | 2025-Q3 stale |
| Cubist Systematic Strategies, LLC trimmed | 54,367 | $80K | 0.1% | 2025-Q3 stale |
| ALLIANCEBERNSTEIN L.P. | 59,080 | $80K | 0.1% | 2025-Q1 stale |
| CANADA PENSION PLAN INVESTMENT BOARD added | 61,400 | $75K | 0.1% | 2025-Q4 stale |
| Legal & General Group Plc | 52,961 | $72K | 0.1% | 2025-Q1 stale |
| DEUTSCHE BANK AG\ trimmed | 47,472 | $64K | 0.1% | 2025-Q1 stale |
| AQR CAPITAL MANAGEMENT LLC trimmed | 53,683 | $62K | 0.1% | 2025-Q2 stale |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 46,051 | $62K | 0.1% | 2025-Q1 stale |
| ALPS ADVISORS INC trimmed | 45,261 | $61K | 0.1% | 2025-Q1 stale |
| FRANKLIN RESOURCES INC trimmed | 35,583 | $48K | 0.1% | 2025-Q1 stale |
| Persistent Asset Partners Ltd new | 38,831 | $47K | 0.1% | 2025-Q4 stale |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 33,923 | $46K | 0.1% | 2025-Q1 stale |
| Corebridge Financial, Inc. trimmed | 27,915 | $38K | 0.0% | 2025-Q1 stale |
| Engineers Gate Manager LP added | 30,544 | $37K | 0.0% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.