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Institutional Ownership · SEC Form 13F

Who owns PCVX (PCVX)


Which tracked institutional funds hold PCVX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PCVX company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

338
Institutional holders
161,963,338
Shares held (tracked funds)

How the tape is positioned

The tracked-fund tape on PCVX is one-sided between 2025-Q4 and 2026-Q1: 158 added or opened and 33 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

PCVX’s largest tracked holder by dollar value, JANUS HENDERSON GROUP PLC, sizes it at 0.5% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 0.4pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in PCVX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 336 tracked filers holding PCVX, 197 increased or opened the position and 113 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in PCVX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 36

  • VANGUARD PORTFOLIO MANAGEMENT LLC$365M
  • VANGUARD CAPITAL MANAGEMENT LLC$364M
  • Bellevue Group AG$69M
  • VANGUARD FIDUCIARY TRUST CO$49M
  • BAUPOST GROUP LLC/MA$46M
  • Jones Hill Capital LP$37M

Full exits 9

  • VANGUARD GROUP INC$554M
  • EcoR1 Capital, LLC$21M
  • TANG CAPITAL MANAGEMENT LLC$13M
  • Jump Financial, LLC$4M
  • TUDOR INVESTMENT CORP ET AL$3M
  • HARBOR CAPITAL ADVISORS, INC.$1M

Largest adds

  • T. Rowe Price Investment Management, Inc.$396M
  • JANUS HENDERSON GROUP PLC$343M
  • FMR LLC$320M
  • RA CAPITAL MANAGEMENT, L.P.$172M
  • Paradigm Biocapital Advisors LP$91M
  • FARALLON CAPITAL MANAGEMENT LLC$73M

Largest trims

  • ADAGE CAPITAL PARTNERS GP, L.L.C.$59M
  • NORGES BANK$23M
  • Logos Global Management LP$13M
  • BARCLAYS PLC$12M
  • AMERIPRISE FINANCIAL INC$8M
  • Soleus Capital Management, L.P.$6M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
JANUS HENDERSON GROUP PLC added16,575,875$960M9.7%2026-Q1
FMR LLC added16,492,861$958M9.7%2026-Q1
T. Rowe Price Investment Management, Inc. added12,126,017$705M7.1%2026-Q1
RA CAPITAL MANAGEMENT, L.P. added11,474,599$667M6.8%2026-Q1
BlackRock, Inc. trimmed9,313,905$541M5.5%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new6,279,545$365M3.7%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new6,266,701$364M3.7%2026-Q1
WELLINGTON MANAGEMENT GROUP LLP trimmed5,603,805$326M3.3%2026-Q1
Paradigm Biocapital Advisors LP added4,793,020$279M2.8%2026-Q1
STATE STREET CORP trimmed4,440,519$258M2.6%2026-Q1
Deep Track Capital, LP added4,300,000$250M2.5%2026-Q1
WESTFIELD CAPITAL MANAGEMENT CO LP added3,646,138$212M2.1%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added3,201,283$186M1.9%2026-Q1
Kynam Capital Management, LP2,922,335$170M1.7%2026-Q1
D. E. Shaw & Co., Inc. trimmed2,865,318$167M1.7%2026-Q1
Caligan Partners LP added2,060,719$120M1.2%2026-Q1
JENNISON ASSOCIATES LLC added1,698,011$99M1.0%2026-Q1
Polar Capital Holdings Plc trimmed1,425,788$83M0.8%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added1,403,948$82M0.8%2026-Q1
MAVERICK CAPITAL LTD added1,377,738$80M0.8%2026-Q1
EVENTIDE ASSET MANAGEMENT, LLC added1,374,292$80M0.8%2026-Q1
Pivotal bioVenture Partners Investment Advisor LLC1,372,425$80M0.8%2026-Q1
UBS Group AG added1,337,390$78M0.8%2026-Q1
GOLDMAN SACHS GROUP INC added1,275,036$74M0.8%2026-Q1
FARALLON CAPITAL MANAGEMENT LLC added1,261,000$73M0.7%2026-Q1
BANK OF AMERICA CORP /DE/ added1,216,843$71M0.7%2026-Q1
Bellevue Group AG added1,190,697$69M0.7%2026-Q1
Assenagon Asset Management S.A. added1,164,813$68M0.7%2026-Q1
NORTHERN TRUST CORP added1,144,469$67M0.7%2026-Q1
Aberdeen Group plc trimmed978,969$57M0.6%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ trimmed976,429$57M0.6%2026-Q1
JPMORGAN CHASE & CO trimmed1,008,314$55M0.6%2026-Q1
Eversept Partners, LP trimmed924,193$54M0.5%2026-Q1
Capital Research Global Investors added912,688$53M0.5%2026-Q1
NOVO HOLDINGS A/S trimmed860,000$50M0.5%2026-Q1
VANGUARD FIDUCIARY TRUST CO new842,273$49M0.5%2026-Q1
Saturn V Capital Management LP added824,532$48M0.5%2026-Q1
BAUPOST GROUP LLC/MA new800,000$46M0.5%2026-Q1
MORGAN STANLEY trimmed735,907$43M0.4%2026-Q1
Pictet Asset Management Holding SA trimmed700,311$41M0.4%2026-Q1
Trails Edge Capital Partners, LP trimmed662,470$38M0.4%2026-Q1
Jones Hill Capital LP new644,831$37M0.4%2026-Q1
Point72 Asset Management, L.P. added620,401$36M0.4%2026-Q1
NORGES BANK trimmed899,842$34M0.3%2026-Q1
FEDERATED HERMES, INC. added566,828$33M0.3%2026-Q1
BOOTHBAY FUND MANAGEMENT, LLC added522,019$30M0.3%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. added514,577$30M0.3%2026-Q1
BROWN ADVISORY INC trimmed511,701$30M0.3%2026-Q1
VICTORY CAPITAL MANAGEMENT INC trimmed501,857$29M0.3%2026-Q1
Bank of New York Mellon Corp added474,526$28M0.3%2026-Q1
FRANKLIN RESOURCES INC added473,363$28M0.3%2026-Q1
Ensign Peak Advisors, Inc trimmed445,903$26M0.3%2026-Q1
Alyeska Investment Group, L.P. added435,581$25M0.3%2026-Q1
Ikarian Capital, LLC added428,682$25M0.3%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added410,605$24M0.2%2026-Q1
Soleus Capital Management, L.P. trimmed385,472$22M0.2%2026-Q1
DIMENSIONAL FUND ADVISORS LP added375,772$22M0.2%2026-Q1
ALGERT GLOBAL LLC added363,984$21M0.2%2026-Q1
AMERICAN CENTURY COMPANIES INC trimmed355,854$21M0.2%2026-Q1
ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed350,000$20M0.2%2026-Q1
Boxer Capital Management, LLC new325,000$19M0.2%2026-Q1
Nuveen, LLC added320,789$19M0.2%2026-Q1
Elmind Capital, LP added316,500$18M0.2%2026-Q1
Candriam S.C.A. added315,022$18M0.2%2026-Q1
TD Asset Management Inc trimmed312,762$18M0.2%2026-Q1
Logos Global Management LP trimmed300,000$17M0.2%2026-Q1
DEUTSCHE BANK AG\ trimmed299,693$17M0.2%2026-Q1
Artisan Partners Limited Partnership trimmed297,432$17M0.2%2026-Q1
MILLENNIUM MANAGEMENT LLC trimmed293,695$17M0.2%2026-Q1
Rosalind Advisors, Inc. new290,000$17M0.2%2026-Q1
Woodline Partners LP274,740$16M0.2%2026-Q1
FRED ALGER MANAGEMENT, LLC added270,115$16M0.2%2026-Q1
ADAR1 Capital Management, LLC trimmed259,137$15M0.2%2026-Q1
JANE STREET GROUP, LLC trimmed252,877$15M0.1%2026-Q1
RAYMOND JAMES FINANCIAL INC added260,395$15M0.1%2026-Q1
Spruce Street Capital LP trimmed245,709$14M0.1%2026-Q1
University of Wisconsin Foundation trimmed239,749$14M0.1%2026-Q1
Nantahala Capital Management, LLC new238,746$14M0.1%2026-Q1
Swiss National Bank added233,100$14M0.1%2026-Q1
Freestone Grove Partners LP added224,731$13M0.1%2026-Q1
BNP PARIBAS FINANCIAL MARKETS added224,518$13M0.1%2026-Q1
CITADEL ADVISORS LLC trimmed197,600$11M0.1%2026-Q1
C WorldWide Group Holding A/S195,000$11M0.1%2026-Q1
SEGALL BRYANT & HAMILL, LLC trimmed187,183$11M0.1%2026-Q1
RHUMBLINE ADVISERS added158,841$9M0.1%2026-Q1
California Public Employees Retirement System added151,555$9M0.1%2026-Q1
VANGUARD GROUP INC trimmed12,014,815$554M5.6%2025-Q4 stale
COMMODORE CAPITAL LP added1,650,000$62M0.6%2025-Q1 stale
Avoro Capital Advisors LLC trimmed1,000,000$38M0.4%2025-Q1 stale
Hood River Capital Management LLC added751,614$28M0.3%2025-Q1 stale
PERCEPTIVE ADVISORS LLC trimmed706,567$27M0.3%2025-Q1 stale
BAKER BROS. ADVISORS LP640,885$23M0.2%2025-Q3 stale
EcoR1 Capital, LLC added450,000$21M0.2%2025-Q4 stale
VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed519,734$19M0.2%2025-Q3 stale
Frazier Life Sciences Management, L.P.474,405$17M0.2%2025-Q3 stale
TANG CAPITAL MANAGEMENT LLC trimmed275,000$13M0.1%2025-Q4 stale
Fiera Capital Corp trimmed345,852$12M0.1%2025-Q3 stale
TimesSquare Capital Management, LLC trimmed281,863$11M0.1%2025-Q1 stale
First Turn Management, LLC276,905$10M0.1%2025-Q1 stale
Siren, L.L.C.295,543$10M0.1%2025-Q2 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership