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Institutional Ownership · SEC Form 13F

Who owns Puma Biotechnology (PBYI)


Which tracked institutional funds hold PBYI, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See PBYI company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

156
Institutional holders
35M
Shares held (tracked funds)
69.4%
Of shares outstanding

How the tape is positioned

The tracked-fund tape on PBYI is one-sided between 2026-Q1 and 2026-Q2: 37 added or opened and 3 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

PBYI’s largest tracked holder by dollar value, ACORN CAPITAL ADVISORS, LLC, sizes it at 9.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 9.1pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in PBYI divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 156 tracked filers holding PBYI, 81 increased or opened the position and 72 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in PBYI between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 2

  • WELLINGTON MANAGEMENT GROUP LLP$1M
  • Trexquant Investment LP$586K

Full exits 2

  • ACADIAN ASSET MANAGEMENT LLC$13M
  • LSV ASSET MANAGEMENT$8M

Largest adds

  • BlackRock, Inc.$8M
  • ACORN CAPITAL ADVISORS, LLC$7M
  • AMERICAN CENTURY COMPANIES INC$7M
  • GEODE CAPITAL MANAGEMENT, LLC$4M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$4M
  • VANGUARD CAPITAL MANAGEMENT LLC$3M

Largest trims

  • MILLENNIUM MANAGEMENT LLC$5M

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
ACORN CAPITAL ADVISORS, LLC4,131,299$34M11.8%2026-Q2
BlackRock, Inc. added3,804,736$31M10.9%2026-Q2
AMERICAN CENTURY COMPANIES INC added2,319,996$19M6.7%2026-Q2
RENAISSANCE TECHNOLOGIES LLC trimmed1,836,213$15M5.3%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added1,835,643$15M5.3%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC added1,825,599$15M5.2%2026-Q2
DIMENSIONAL FUND ADVISORS LP added1,518,014$12M4.4%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added1,339,405$11M3.8%2026-Q2
O'SHAUGHNESSY ASSET MANAGEMENT, LLC trimmed1,123,783$9M3.2%2026-Q2
STATE STREET CORP added952,165$8M2.7%2026-Q2
KENNEDY CAPITAL MANAGEMENT LLC trimmed873,253$7M2.5%2026-Q2
BRIDGEWAY CAPITAL MANAGEMENT, LLC added791,616$6M2.3%2026-Q2
RITHOLTZ WEALTH MANAGEMENT trimmed749,798$6M2.1%2026-Q2
AQR CAPITAL MANAGEMENT LLC trimmed725,192$6M2.1%2026-Q2
GOLDMAN SACHS GROUP INC trimmed669,156$5M1.9%2026-Q2
NORTHERN TRUST CORP added652,386$5M1.9%2026-Q2
Connor, Clark & Lunn Investment Management Ltd. trimmed642,946$5M1.8%2026-Q2
UBS Group AG added636,761$5M1.8%2026-Q2
MILLENNIUM MANAGEMENT LLC trimmed602,240$5M1.7%2026-Q2
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP trimmed532,450$4M1.5%2026-Q2
SEI INVESTMENTS CO trimmed418,669$3M1.2%2026-Q2
GLOBEFLEX CAPITAL L P added382,807$3M1.1%2026-Q2
Bank of New York Mellon Corp added360,734$3M1.0%2026-Q2
D. E. Shaw & Co., Inc. trimmed316,343$3M0.9%2026-Q2
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM added309,106$3M0.9%2026-Q2
Invesco Ltd. added301,002$2M0.9%2026-Q2
Russell Investments Group, Ltd. added272,234$2M0.8%2026-Q2
VANGUARD FIDUCIARY TRUST CO added269,070$2M0.8%2026-Q2
MORGAN STANLEY trimmed265,670$2M0.8%2026-Q2
FEDERATED HERMES, INC. added250,766$2M0.7%2026-Q2
Empowered Funds, LLC added220,316$2M0.6%2026-Q2
PANAGORA ASSET MANAGEMENT INC added217,545$2M0.6%2026-Q2
PRUDENTIAL FINANCIAL INC trimmed213,599$2M0.6%2026-Q2
FMR LLC added211,444$2M0.6%2026-Q2
JPMORGAN CHASE & CO trimmed211,339$2M0.6%2026-Q2
STATE OF WISCONSIN INVESTMENT BOARD trimmed188,232$2M0.5%2026-Q2
FRANKLIN RESOURCES INC trimmed172,010$1M0.5%2026-Q2
Prospera Financial Services Inc trimmed158,762$1M0.5%2026-Q2
Haven Private, LLC trimmed148,448$1M0.4%2026-Q2
TWO SIGMA INVESTMENTS, LP added140,587$1M0.4%2026-Q2
FIRST TRUST ADVISORS LP added130,206$1M0.4%2026-Q2
Round Rock Advisors LLC128,912$1M0.4%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added128,243$1M0.4%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP trimmed126,091$1M0.4%2026-Q2
STRS OHIO trimmed84,600$686K0.2%2026-Q2
Nuveen, LLC added82,298$667K0.2%2026-Q2
EVERGREEN CAPITAL MANAGEMENT LLC trimmed73,731$598K0.2%2026-Q2
CANADA PENSION PLAN INVESTMENT BOARD added73,500$596K0.2%2026-Q2
Trexquant Investment LP new72,223$586K0.2%2026-Q2
Vise Technologies, Inc. added72,030$584K0.2%2026-Q2
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.61,255$497K0.2%2026-Q2
OpenArc Corporate Advisory, LLC trimmed59,491$482K0.2%2026-Q2
RHUMBLINE ADVISERS added57,510$466K0.2%2026-Q2
D'Orazio & Associates, Inc. trimmed48,680$395K0.1%2026-Q2
Vanguard Global Advisers, LLC added46,267$375K0.1%2026-Q2
DEUTSCHE BANK AG\ added43,192$350K0.1%2026-Q2
Man Group plc trimmed41,506$337K0.1%2026-Q2
WINTON GROUP Ltd trimmed40,509$329K0.1%2026-Q2
XTX Topco Ltd added40,296$327K0.1%2026-Q2
State of Wyoming trimmed39,833$323K0.1%2026-Q2
WELLS FARGO & COMPANY/MN added37,606$305K0.1%2026-Q2
EntryPoint Capital, LLC trimmed37,386$303K0.1%2026-Q2
Baron Wealth Management LLC trimmed36,372$295K0.1%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ added36,343$295K0.1%2026-Q2
Creative Planning added35,737$290K0.1%2026-Q2
LPL Financial LLC trimmed34,537$280K0.1%2026-Q2
Universal- Beteiligungs- und Servicegesellschaft mbH trimmed34,485$280K0.1%2026-Q2
BANK OF AMERICA CORP /DE/ trimmed31,747$257K0.1%2026-Q2
Kathmere Capital Management, LLC added31,172$253K0.1%2026-Q2
ENVESTNET ASSET MANAGEMENT INC added29,190$237K0.1%2026-Q2
Y-Intercept (Hong Kong) Ltd new26,222$213K0.1%2026-Q2
MARTINGALE ASSET MANAGEMENT L P new25,364$206K0.1%2026-Q2
Metis Global Partners, LLC25,264$205K0.1%2026-Q2
MetLife Investment Management, LLC added24,873$202K0.1%2026-Q2
C2C Wealth Management, LLC23,620$192K0.1%2026-Q2
CITIGROUP INC added21,666$176K0.1%2026-Q2
PRELUDE CAPITAL MANAGEMENT, LLC added21,548$175K0.1%2026-Q2
ALLIANCEBERNSTEIN L.P. added21,360$136K0.0%2026-Q2
One Wealth Advisors, LLC21,079$171K0.1%2026-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. trimmed20,383$165K0.1%2026-Q2
BAILARD, INC.18,100$147K0.1%2026-Q2
Allspring Global Investments Holdings, LLC added17,945$143K0.1%2026-Q2
Spark Investment Management LLC new17,000$138K0.0%2026-Q2
Police & Firemen's Retirement System of New Jersey15,719$127K0.0%2026-Q2
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed15,476$126K0.0%2026-Q2
Lido Advisors, LLC new15,045$122K0.0%2026-Q2
Mariner, LLC added14,869$121K0.0%2026-Q2
Caprock Group, LLC trimmed13,862$112K0.0%2026-Q2
PERKINS CAPITAL MANAGEMENT INC added13,400$109K0.0%2026-Q2
TOCQUEVILLE ASSET MANAGEMENT L.P. added13,312$108K0.0%2026-Q2
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC added13,203$106K0.0%2026-Q2
OSAIC HOLDINGS, INC. added12,169$99K0.0%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE added12,056$98K0.0%2026-Q2
R Squared Ltd added11,991$97K0.0%2026-Q2
Abel Hall, LLC added11,520$93K0.0%2026-Q2
BARCLAYS PLC trimmed11,202$91K0.0%2026-Q2
IEQ CAPITAL, LLC trimmed10,671$87K0.0%2026-Q2
Cerity Partners LLC trimmed10,512$85K0.0%2026-Q2
Williams & Novak, LLC trimmed10,489$85K0.0%2026-Q2
Vanguard Personalized Indexing Management, LLC new10,408$84K0.0%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership