Who owns Milestone Pharmaceuticals (MIST)
Which tracked institutional funds hold MIST, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See MIST company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on MIST is one-sided between 2026-Q1 and 2026-Q2: 9 added or opened and 2 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
MIST’s largest tracked holder by dollar value, Pavaki Capital Management LLC, sizes it at 6.9% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 6.9pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in MIST divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 74 tracked filers holding MIST, 27 increased or opened the position and 40 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in MIST between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 2
- Kalehua Capital Management LLC$2M
- AMERIPRISE FINANCIAL INC$893K
Full exits 1
- GOLDMAN SACHS GROUP INC$2M
Largest adds
- Point72 Asset Management, L.P.$6M
- Propel Bio Management, LLC$5M
- RTW INVESTMENTS, LP$3M
- Simplify Asset Management Inc.$3M
- MILLENNIUM MANAGEMENT LLC$2M
- Pavaki Capital Management LLC$1M
Largest trims
- BALYASNY ASSET MANAGEMENT L.P.$718K
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Pavaki Capital Management LLC added | 9,067,848 | $12M | 12.9% | 2026-Q2 |
| RTW INVESTMENTS, LP added | 7,833,336 | $10M | 11.1% | 2026-Q2 |
| Propel Bio Management, LLC added | 7,429,590 | $10M | 10.6% | 2026-Q2 |
| Point72 Asset Management, L.P. added | 5,411,138 | $7M | 7.7% | 2026-Q2 |
| Simplify Asset Management Inc. added | 3,349,379 | $4M | 4.8% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC added | 3,142,219 | $4M | 4.5% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP trimmed | 2,040,015 | $3M | 2.9% | 2026-Q2 |
| MARSHALL WACE, LLP trimmed | 1,797,695 | $2M | 2.6% | 2026-Q2 |
| Kalehua Capital Management LLC new | 1,269,237 | $2M | 1.8% | 2026-Q2 |
| Lion Point Capital, LP | 820,000 | $1M | 1.2% | 2026-Q2 |
| TORONTO DOMINION BANK | 750,000 | $1M | 1.1% | 2026-Q2 |
| Boxer Capital Management, LLC | 666,666 | $893K | 0.9% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC new | 666,666 | $893K | 0.9% | 2026-Q2 |
| MORGAN STANLEY trimmed | 635,211 | $851K | 0.9% | 2026-Q2 |
| UBS Group AG trimmed | 465,403 | $624K | 0.7% | 2026-Q2 |
| BOOTHBAY FUND MANAGEMENT, LLC added | 462,669 | $620K | 0.7% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 359,895 | $482K | 0.5% | 2026-Q2 |
| Aptus Capital Advisors, LLC added | 339,450 | $455K | 0.5% | 2026-Q2 |
| GUARDIAN WEALTH ADVISORS, LLC / NC added | 339,450 | $455K | 0.5% | 2026-Q2 |
| Seven Fleet Capital Management LP trimmed | 270,233 | $362K | 0.4% | 2026-Q2 |
| Squarepoint Ops LLC trimmed | 231,824 | $311K | 0.3% | 2026-Q2 |
| LPL Financial LLC added | 220,873 | $296K | 0.3% | 2026-Q2 |
| BALYASNY ASSET MANAGEMENT L.P. trimmed | 220,498 | $295K | 0.3% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS trimmed | 173,704 | $233K | 0.2% | 2026-Q2 |
| TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC added | 150,000 | $201K | 0.2% | 2026-Q2 |
| Wealthspire Advisors, LLC added | 140,629 | $188K | 0.2% | 2026-Q2 |
| Valeo Financial Advisors, LLC | 130,699 | $175K | 0.2% | 2026-Q2 |
| ADAR1 Capital Management, LLC | 100,000 | $134K | 0.1% | 2026-Q2 |
| Cascades Capital Asset Management, LLC added | 83,610 | $112K | 0.1% | 2026-Q2 |
| Quadrature Capital Ltd trimmed | 64,661 | $87K | 0.1% | 2026-Q2 |
| JANE STREET GROUP, LLC trimmed | 57,787 | $77K | 0.1% | 2026-Q2 |
| SIMPLEX TRADING, LLC trimmed | 54,171 | $73K | 0.1% | 2026-Q2 |
| Bay Rivers Group added | 46,633 | $62K | 0.1% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC | 40,789 | $55K | 0.1% | 2026-Q2 |
| October Effect Ltd trimmed | 40,000 | $54K | 0.1% | 2026-Q2 |
| Focus Partners Wealth | 36,000 | $48K | 0.1% | 2026-Q2 |
| CITADEL ADVISORS LLC trimmed | 32,887 | $44K | 0.0% | 2026-Q2 |
| RAYMOND JAMES FINANCIAL INC added | 30,070 | $40K | 0.0% | 2026-Q2 |
| Federation des caisses Desjardins du Quebec | 29,781 | $40K | 0.0% | 2026-Q2 |
| Mariner, LLC trimmed | 27,830 | $37K | 0.0% | 2026-Q2 |
| XTX Topco Ltd trimmed | 26,317 | $35K | 0.0% | 2026-Q2 |
| Welch & Forbes LLC | 25,000 | $34K | 0.0% | 2026-Q2 |
| Tower Research Capital LLC (TRC) added | 24,185 | $32K | 0.0% | 2026-Q2 |
| NATIONAL BANK OF CANADA /FI/ | 23,500 | $31K | 0.0% | 2026-Q2 |
| Exit Wealth Advisors, LLC. added | 22,692 | $30K | 0.0% | 2026-Q2 |
| STATE STREET CORP added | 22,564 | $30K | 0.0% | 2026-Q2 |
| Taylor Financial Group, Inc. added | 20,000 | $27K | 0.0% | 2026-Q2 |
| Stephenson & Company, Inc. | 20,000 | $27K | 0.0% | 2026-Q2 |
| TWO SIGMA SECURITIES, LLC trimmed | 16,745 | $22K | 0.0% | 2026-Q2 |
| Cetera Investment Advisers added | 16,368 | $22K | 0.0% | 2026-Q2 |
| Pathstone Holdings, LLC trimmed | 15,500 | $21K | 0.0% | 2026-Q2 |
| AE Wealth Management LLC | 15,000 | $20K | 0.0% | 2026-Q2 |
| Vision Retirement, LLC | 15,000 | $20K | 0.0% | 2026-Q2 |
| JONES FINANCIAL COMPANIES LLLP | 16,000 | $20K | 0.0% | 2026-Q2 |
| EARNED WEALTH ADVISORS, LLC | 14,756 | $20K | 0.0% | 2026-Q2 |
| Bronte Capital Management Pty Ltd. added | 14,390 | $19K | 0.0% | 2026-Q2 |
| WINTON GROUP Ltd new | 14,300 | $19K | 0.0% | 2026-Q2 |
| Beta Wealth Group, Inc. | 14,127 | $19K | 0.0% | 2026-Q2 |
| Strategic Family Wealth Counselors, L.L.C. | 13,875 | $19K | 0.0% | 2026-Q2 |
| Creative Planning trimmed | 13,080 | $18K | 0.0% | 2026-Q2 |
| Rockefeller Capital Management L.P. | 12,500 | $17K | 0.0% | 2026-Q2 |
| Safeguard Investment Advisory Group, LLC trimmed | 12,406 | $17K | 0.0% | 2026-Q2 |
| Eaton Financial Holdings Company, LLC | 10,250 | $14K | 0.0% | 2026-Q2 |
| Secure Asset Management, LLC | 10,000 | $13K | 0.0% | 2026-Q2 |
| INTEGRAL INVESTMENT ADVISORS, INC. | 10,000 | $13K | 0.0% | 2026-Q2 |
| ROYAL BANK OF CANADA | 6,698 | $9K | 0.0% | 2026-Q2 |
| US BANCORP \DE\ | 3,200 | $4K | 0.0% | 2026-Q2 |
| Arax Advisory Partners added | 3,053 | $4K | 0.0% | 2026-Q2 |
| PNC Financial Services Group, Inc. added | 2,800 | $4K | 0.0% | 2026-Q2 |
| Medallion Wealth Advisors, LLC | 340 | $456 | 0.0% | 2026-Q2 |
| Rialto Wealth Management, LLC | 300 | $402 | 0.0% | 2026-Q2 |
| GROUP ONE TRADING LLC trimmed | 224 | $300 | 0.0% | 2026-Q2 |
| Caitong International Asset Management Co., Ltd trimmed | 94 | $126 | 0.0% | 2026-Q2 |
| SBI Securities Co., Ltd. trimmed | 6 | $8 | 0.0% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 2,000,025 | $2M | 2.5% | 2026-Q1 stale (1 quarter behind) |
| RENAISSANCE TECHNOLOGIES LLC new | 129,705 | $154K | 0.2% | 2026-Q1 stale (1 quarter behind) |
| HRT FINANCIAL LP trimmed | 62,256 | $74K | 0.1% | 2026-Q1 stale (1 quarter behind) |
| Cambridge Investment Research Advisors, Inc. added | 59,620 | $71K | 0.1% | 2026-Q1 stale (1 quarter behind) |
| SG Americas Securities, LLC trimmed | 42,512 | $51K | 0.1% | 2026-Q1 stale (1 quarter behind) |
| Invesco Ltd. added | 41,356 | $49K | 0.1% | 2026-Q1 stale (1 quarter behind) |
| NORTHERN TRUST CORP trimmed | 38,779 | $46K | 0.0% | 2026-Q1 stale (1 quarter behind) |
| GSA CAPITAL PARTNERS LLP trimmed | 26,893 | $32K | 0.0% | 2026-Q1 stale (1 quarter behind) |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 2,810,037 | $6M | 6.0% | 2025-Q4 stale (2 quarters behind) |
| Stonepine Capital Management, LLC added | 662,666 | $1M | 1.4% | 2025-Q4 stale (2 quarters behind) |
| TWO SIGMA ADVISERS, LP added | 619,592 | $1M | 1.3% | 2025-Q4 stale (2 quarters behind) |
| NOMURA HOLDINGS INC new | 225,000 | $454K | 0.5% | 2025-Q4 stale (2 quarters behind) |
| Graham Capital Management, L.P. new | 133,620 | $270K | 0.3% | 2025-Q4 stale (2 quarters behind) |
| Engineers Gate Manager LP added | 59,053 | $119K | 0.1% | 2025-Q4 stale (2 quarters behind) |
| Qube Research & Technologies Ltd new | 34,596 | $70K | 0.1% | 2025-Q4 stale (2 quarters behind) |
| CITIGROUP INC added | 33,858 | $68K | 0.1% | 2025-Q4 stale (2 quarters behind) |
| Scientech Research LLC added | 30,124 | $61K | 0.1% | 2025-Q4 stale (2 quarters behind) |
| Quantbot Technologies LP new | 18,990 | $38K | 0.0% | 2025-Q4 stale (2 quarters behind) |
| ORBIMED ADVISORS LLC added | 3,221,828 | $6M | 6.8% | 2025-Q3 stale (3 quarters behind) |
| SPHERA FUNDS MANAGEMENT LTD. new | 820,000 | $2M | 1.7% | 2025-Q3 stale (3 quarters behind) |
| Affinity Asset Advisors, LLC new | 666,666 | $1M | 1.4% | 2025-Q3 stale (3 quarters behind) |
| AMH Equity Ltd new | 231,671 | $463K | 0.5% | 2025-Q3 stale (3 quarters behind) |
| Alta Fundamental Advisers LLC trimmed | 1,398,977 | $3M | 2.9% | 2025-Q2 stale (4 quarters behind) |
| BML Capital Management, LLC | 1,136,091 | $2M | 2.3% | 2025-Q2 stale (4 quarters behind) |
| Bleichroeder LP | 500,000 | $970K | 1.0% | 2025-Q2 stale (4 quarters behind) |
| Walleye Capital LLC trimmed | 15,109 | $29K | 0.0% | 2025-Q2 stale (4 quarters behind) |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.