Who owns Seres Therapeutics, Inc. (MCRB)
Which tracked institutional funds hold MCRB, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See MCRB company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-15). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on MCRB is one-sided between 2025-Q4 and 2026-Q1: 2 added or opened and 9 trimmed or exited — on balance reducing.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
MCRB’s largest tracked holder by dollar value, Flagship Pioneering, LLC, sizes it at 0.9% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.9pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in MCRB divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 33 tracked filers holding MCRB, 15 increased or opened the position and 17 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in MCRB between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 1
- VANGUARD CAPITAL MANAGEMENT LLC$3M
Full exits 3
- VANGUARD GROUP INC$5M
- HRT FINANCIAL LP$935K
- 683 Capital Management, LLC$778K
Largest adds
- AMERICAN CENTURY COMPANIES INC$311K
Largest trims
- Flagship Pioneering, LLC$7M
- SUSQUEHANNA INTERNATIONAL GROUP, LLP$2M
- MARSHALL WACE, LLP$684K
- BlackRock, Inc.$637K
- GEODE CAPITAL MANAGEMENT, LLC$618K
- Vontobel Holding Ltd.$308K
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Flagship Pioneering, LLC | 1,155,850 | $10M | 33.9% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 294,143 | $3M | 8.6% | 2026-Q1 |
| Vontobel Holding Ltd. added | 138,468 | $1M | 4.1% | 2026-Q1 |
| MARSHALL WACE, LLP added | 124,481 | $1M | 3.6% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 105,339 | $934K | 3.1% | 2026-Q1 |
| BlackRock, Inc. trimmed | 102,026 | $905K | 3.0% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC trimmed | 74,835 | $664K | 2.2% | 2026-Q1 |
| AMERICAN CENTURY COMPANIES INC added | 62,316 | $553K | 1.8% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 39,643 | $352K | 1.2% | 2026-Q1 |
| STATE STREET CORP | 33,901 | $301K | 1.0% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 31,630 | $281K | 0.9% | 2026-Q1 |
| Lion Point Capital, LP | 31,570 | $280K | 0.9% | 2026-Q1 |
| MORGAN STANLEY trimmed | 21,700 | $192K | 0.6% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP trimmed | 18,794 | $167K | 0.6% | 2026-Q1 |
| NORTHERN TRUST CORP | 14,765 | $131K | 0.4% | 2026-Q1 |
| Invesco Ltd. added | 14,547 | $129K | 0.4% | 2026-Q1 |
| UBS Group AG added | 7,030 | $62K | 0.2% | 2026-Q1 |
| BARCLAYS PLC trimmed | 6,507 | $58K | 0.2% | 2026-Q1 |
| SBI Securities Co., Ltd. | 3,482 | $31K | 0.1% | 2026-Q1 |
| SIMPLEX TRADING, LLC added | 3,070 | $27K | 0.1% | 2026-Q1 |
| Vanguard Global Advisers, LLC new | 1,975 | $18K | 0.1% | 2026-Q1 |
| FMR LLC added | 1,752 | $16K | 0.1% | 2026-Q1 |
| Rachor Investment Advisory Services, LLC | 1,477 | $13K | 0.0% | 2026-Q1 |
| GROUP ONE TRADING LLC trimmed | 824 | $7K | 0.0% | 2026-Q1 |
| Tower Research Capital LLC (TRC) added | 794 | $7K | 0.0% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS trimmed | 211 | $2K | 0.0% | 2026-Q1 |
| Physician Wealth Advisors, Inc. | 142 | $1K | 0.0% | 2026-Q1 |
| ROYAL BANK OF CANADA added | 107 | $1K | 0.0% | 2026-Q1 |
| WELLS FARGO & COMPANY/MN trimmed | 10 | $89 | 0.0% | 2026-Q1 |
| Sound Income Strategies, LLC | 8 | $71 | 0.0% | 2026-Q1 |
| OSAIC HOLDINGS, INC. | 8 | $70 | 0.0% | 2026-Q1 |
| Allworth Financial LP | 4 | $36 | 0.0% | 2026-Q1 |
| Arax Advisory Partners added | 6 | $18 | 0.0% | 2026-Q1 |
| VANGUARD GROUP INC added | 324,214 | $5M | 15.9% | 2025-Q4 stale |
| HRT FINANCIAL LP added | 62,900 | $935K | 3.1% | 2025-Q4 stale |
| 683 Capital Management, LLC new | 52,314 | $778K | 2.6% | 2025-Q4 stale |
| J. Goldman & Co LP new | 27,000 | $519K | 1.7% | 2025-Q3 stale |
| CITADEL ADVISORS LLC added | 31,418 | $468K | 1.5% | 2025-Q4 stale |
| Schonfeld Strategic Advisors LLC added | 29,097 | $433K | 1.4% | 2025-Q4 stale |
| XTX Topco Ltd added | 22,417 | $249K | 0.8% | 2025-Q2 stale |
| Squarepoint Ops LLC trimmed | 20,908 | $232K | 0.8% | 2025-Q2 stale |
| OMERS ADMINISTRATION Corp new | 14,400 | $214K | 0.7% | 2025-Q4 stale |
| GOLDMAN SACHS GROUP INC trimmed | 14,340 | $213K | 0.7% | 2025-Q4 stale |
| ExodusPoint Capital Management, LP trimmed | 12,737 | $190K | 0.6% | 2025-Q4 stale |
| TANG CAPITAL MANAGEMENT LLC trimmed | 13,921 | $155K | 0.5% | 2025-Q2 stale |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC trimmed | 12,500 | $139K | 0.5% | 2025-Q2 stale |
| Providence Wealth Advisors, LLC | 105,000 | $71K | 0.2% | 2025-Q1 stale |
| LPL Financial LLC added | 95,137 | $67K | 0.2% | 2025-Q1 stale |
| CITIGROUP INC added | 2,621 | $50K | 0.2% | 2025-Q3 stale |
| TUDOR INVESTMENT CORP ET AL | 61,977 | $43K | 0.1% | 2025-Q1 stale |
| Vanguard Personalized Indexing Management, LLC trimmed | 50,720 | $36K | 0.1% | 2025-Q1 stale |
| Engineers Gate Manager LP trimmed | 47,637 | $33K | 0.1% | 2025-Q1 stale |
| AVANTAX ADVISORY SERVICES, INC. | 45,179 | $32K | 0.1% | 2025-Q1 stale |
| Kestra Advisory Services, LLC | 38,471 | $27K | 0.1% | 2025-Q1 stale |
| CANTOR FITZGERALD, L. P. trimmed | 37,475 | $26K | 0.1% | 2025-Q1 stale |
| IRONWOOD INVESTMENT MANAGEMENT LLC trimmed | 36,494 | $26K | 0.1% | 2025-Q1 stale |
| MILLENNIUM MANAGEMENT LLC trimmed | 29,550 | $21K | 0.1% | 2025-Q1 stale |
| TWO SIGMA SECURITIES, LLC trimmed | 25,588 | $18K | 0.1% | 2025-Q1 stale |
| Arete Wealth Advisors, LLC | 20,900 | $15K | 0.0% | 2025-Q1 stale |
| STIFEL FINANCIAL CORP | 20,000 | $14K | 0.0% | 2025-Q1 stale |
| Janney Montgomery Scott LLC trimmed | 20,000 | $14K | 0.0% | 2025-Q1 stale |
| MML INVESTORS SERVICES, LLC | 15,864 | $11K | 0.0% | 2025-Q1 stale |
| VICTORY CAPITAL MANAGEMENT INC trimmed | 15,342 | $11K | 0.0% | 2025-Q1 stale |
| Miller Financial Services LLC new | 15,000 | $11K | 0.0% | 2025-Q1 stale |
| Aries Wealth Management | 15,000 | $11K | 0.0% | 2025-Q1 stale |
| CAPTRUST FINANCIAL ADVISORS | 13,100 | $9K | 0.0% | 2025-Q1 stale |
| PEAPACK GLADSTONE FINANCIAL CORP new | 13,000 | $9K | 0.0% | 2025-Q1 stale |
| MISSION WEALTH MANAGEMENT, LP new | 11,495 | $8K | 0.0% | 2025-Q1 stale |
| COMMONWEALTH EQUITY SERVICES, LLC | 11,598 | $8K | 0.0% | 2025-Q1 stale |
| Diversified Trust Co | 10,000 | $7K | 0.0% | 2025-Q1 stale |
| Integrated Wealth Concepts LLC | 10,000 | $7K | 0.0% | 2025-Q1 stale |
| Atlantic Union Bankshares Corp new | 411 | $5K | 0.0% | 2025-Q2 stale |
| BANK OF AMERICA CORP /DE/ trimmed | 195 | $3K | 0.0% | 2025-Q4 stale |
| JPMORGAN CHASE & CO | 65 | $1K | 0.0% | 2025-Q3 stale |
| TFC Financial Management, Inc. | 1,000 | $701 | 0.0% | 2025-Q1 stale |
| Continuum Advisory, LLC | 955 | $669 | 0.0% | 2025-Q1 stale |
| RAYMOND JAMES FINANCIAL INC new | 56 | $623 | 0.0% | 2025-Q2 stale |
| EverSource Wealth Advisors, LLC | 666 | $466 | 0.0% | 2025-Q1 stale |
| Sandy Spring Bank | 345 | $242 | 0.0% | 2025-Q1 stale |
| US BANCORP \DE\ trimmed | 12 | $231 | 0.0% | 2025-Q3 stale |
| NISA INVESTMENT ADVISORS, LLC trimmed | 200 | $140 | 0.0% | 2025-Q1 stale |
| Farther Finance Advisors, LLC | 204 | $138 | 0.0% | 2025-Q1 stale |
| Federation des caisses Desjardins du Quebec new | 3 | $58 | 0.0% | 2025-Q3 stale |
| WHITTIER TRUST CO trimmed | 1 | $11 | 0.0% | 2025-Q2 stale |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | — | 0.0% | 2025-Q1 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.