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Institutional Ownership · SEC Form 13F

Who owns Seres Therapeutics, Inc. (MCRB)


Which tracked institutional funds hold MCRB, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See MCRB company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-15). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

33
Institutional holders
2M
Shares held (tracked funds)
24.0%
Of shares outstanding

How the tape is positioned

The tracked-fund tape on MCRB is one-sided between 2025-Q4 and 2026-Q1: 2 added or opened and 9 trimmed or exited — on balance reducing.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

MCRB’s largest tracked holder by dollar value, Flagship Pioneering, LLC, sizes it at 0.9% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.9pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in MCRB divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 33 tracked filers holding MCRB, 15 increased or opened the position and 17 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in MCRB between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 1

  • VANGUARD CAPITAL MANAGEMENT LLC$3M

Full exits 3

  • VANGUARD GROUP INC$5M
  • HRT FINANCIAL LP$935K
  • 683 Capital Management, LLC$778K

Largest adds

  • AMERICAN CENTURY COMPANIES INC$311K

Largest trims

  • Flagship Pioneering, LLC$7M
  • SUSQUEHANNA INTERNATIONAL GROUP, LLP$2M
  • MARSHALL WACE, LLP$684K
  • BlackRock, Inc.$637K
  • GEODE CAPITAL MANAGEMENT, LLC$618K
  • Vontobel Holding Ltd.$308K

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
Flagship Pioneering, LLC1,155,850$10M33.9%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new294,143$3M8.6%2026-Q1
Vontobel Holding Ltd. added138,468$1M4.1%2026-Q1
MARSHALL WACE, LLP added124,481$1M3.6%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed105,339$934K3.1%2026-Q1
BlackRock, Inc. trimmed102,026$905K3.0%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC trimmed74,835$664K2.2%2026-Q1
AMERICAN CENTURY COMPANIES INC added62,316$553K1.8%2026-Q1
VANGUARD FIDUCIARY TRUST CO new39,643$352K1.2%2026-Q1
STATE STREET CORP33,901$301K1.0%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added31,630$281K0.9%2026-Q1
Lion Point Capital, LP31,570$280K0.9%2026-Q1
MORGAN STANLEY trimmed21,700$192K0.6%2026-Q1
TWO SIGMA INVESTMENTS, LP trimmed18,794$167K0.6%2026-Q1
NORTHERN TRUST CORP14,765$131K0.4%2026-Q1
Invesco Ltd. added14,547$129K0.4%2026-Q1
UBS Group AG added7,030$62K0.2%2026-Q1
BARCLAYS PLC trimmed6,507$58K0.2%2026-Q1
SBI Securities Co., Ltd.3,482$31K0.1%2026-Q1
SIMPLEX TRADING, LLC added3,070$27K0.1%2026-Q1
Vanguard Global Advisers, LLC new1,975$18K0.1%2026-Q1
FMR LLC added1,752$16K0.1%2026-Q1
Rachor Investment Advisory Services, LLC1,477$13K0.0%2026-Q1
GROUP ONE TRADING LLC trimmed824$7K0.0%2026-Q1
Tower Research Capital LLC (TRC) added794$7K0.0%2026-Q1
BNP PARIBAS FINANCIAL MARKETS trimmed211$2K0.0%2026-Q1
Physician Wealth Advisors, Inc.142$1K0.0%2026-Q1
ROYAL BANK OF CANADA added107$1K0.0%2026-Q1
WELLS FARGO & COMPANY/MN trimmed10$890.0%2026-Q1
Sound Income Strategies, LLC8$710.0%2026-Q1
OSAIC HOLDINGS, INC.8$700.0%2026-Q1
Allworth Financial LP4$360.0%2026-Q1
Arax Advisory Partners added6$180.0%2026-Q1
VANGUARD GROUP INC added324,214$5M15.9%2025-Q4 stale
HRT FINANCIAL LP added62,900$935K3.1%2025-Q4 stale
683 Capital Management, LLC new52,314$778K2.6%2025-Q4 stale
J. Goldman & Co LP new27,000$519K1.7%2025-Q3 stale
CITADEL ADVISORS LLC added31,418$468K1.5%2025-Q4 stale
Schonfeld Strategic Advisors LLC added29,097$433K1.4%2025-Q4 stale
XTX Topco Ltd added22,417$249K0.8%2025-Q2 stale
Squarepoint Ops LLC trimmed20,908$232K0.8%2025-Q2 stale
OMERS ADMINISTRATION Corp new14,400$214K0.7%2025-Q4 stale
GOLDMAN SACHS GROUP INC trimmed14,340$213K0.7%2025-Q4 stale
ExodusPoint Capital Management, LP trimmed12,737$190K0.6%2025-Q4 stale
TANG CAPITAL MANAGEMENT LLC trimmed13,921$155K0.5%2025-Q2 stale
BRIDGEWAY CAPITAL MANAGEMENT, LLC trimmed12,500$139K0.5%2025-Q2 stale
Providence Wealth Advisors, LLC105,000$71K0.2%2025-Q1 stale
LPL Financial LLC added95,137$67K0.2%2025-Q1 stale
CITIGROUP INC added2,621$50K0.2%2025-Q3 stale
TUDOR INVESTMENT CORP ET AL61,977$43K0.1%2025-Q1 stale
Vanguard Personalized Indexing Management, LLC trimmed50,720$36K0.1%2025-Q1 stale
Engineers Gate Manager LP trimmed47,637$33K0.1%2025-Q1 stale
AVANTAX ADVISORY SERVICES, INC.45,179$32K0.1%2025-Q1 stale
Kestra Advisory Services, LLC38,471$27K0.1%2025-Q1 stale
CANTOR FITZGERALD, L. P. trimmed37,475$26K0.1%2025-Q1 stale
IRONWOOD INVESTMENT MANAGEMENT LLC trimmed36,494$26K0.1%2025-Q1 stale
MILLENNIUM MANAGEMENT LLC trimmed29,550$21K0.1%2025-Q1 stale
TWO SIGMA SECURITIES, LLC trimmed25,588$18K0.1%2025-Q1 stale
Arete Wealth Advisors, LLC20,900$15K0.0%2025-Q1 stale
STIFEL FINANCIAL CORP20,000$14K0.0%2025-Q1 stale
Janney Montgomery Scott LLC trimmed20,000$14K0.0%2025-Q1 stale
MML INVESTORS SERVICES, LLC15,864$11K0.0%2025-Q1 stale
VICTORY CAPITAL MANAGEMENT INC trimmed15,342$11K0.0%2025-Q1 stale
Miller Financial Services LLC new15,000$11K0.0%2025-Q1 stale
Aries Wealth Management15,000$11K0.0%2025-Q1 stale
CAPTRUST FINANCIAL ADVISORS13,100$9K0.0%2025-Q1 stale
PEAPACK GLADSTONE FINANCIAL CORP new13,000$9K0.0%2025-Q1 stale
MISSION WEALTH MANAGEMENT, LP new11,495$8K0.0%2025-Q1 stale
COMMONWEALTH EQUITY SERVICES, LLC11,598$8K0.0%2025-Q1 stale
Diversified Trust Co10,000$7K0.0%2025-Q1 stale
Integrated Wealth Concepts LLC10,000$7K0.0%2025-Q1 stale
Atlantic Union Bankshares Corp new411$5K0.0%2025-Q2 stale
BANK OF AMERICA CORP /DE/ trimmed195$3K0.0%2025-Q4 stale
JPMORGAN CHASE & CO65$1K0.0%2025-Q3 stale
TFC Financial Management, Inc.1,000$7010.0%2025-Q1 stale
Continuum Advisory, LLC955$6690.0%2025-Q1 stale
RAYMOND JAMES FINANCIAL INC new56$6230.0%2025-Q2 stale
EverSource Wealth Advisors, LLC666$4660.0%2025-Q1 stale
Sandy Spring Bank345$2420.0%2025-Q1 stale
US BANCORP \DE\ trimmed12$2310.0%2025-Q3 stale
NISA INVESTMENT ADVISORS, LLC trimmed200$1400.0%2025-Q1 stale
Farther Finance Advisors, LLC204$1380.0%2025-Q1 stale
Federation des caisses Desjardins du Quebec new3$580.0%2025-Q3 stale
WHITTIER TRUST CO trimmed1$110.0%2025-Q2 stale
CONCOURSE FINANCIAL GROUP SECURITIES, INC.00.0%2025-Q1 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership