Who owns LYEL (LYEL)
Which tracked institutional funds hold LYEL, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See LYEL company fundamentals →
Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
13 tracked funds added or opened LYEL while 26 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
LYEL’s largest tracked holder by dollar value, ARCH Venture Management, LLC, sizes it at 9.6% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 9.6pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in LYEL divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 74 tracked filers holding LYEL, 42 increased or opened the position and 20 reduced or closed it; over the same quarter, open-market insider Form 4s were net purchases.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in LYEL between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 6
- VANGUARD CAPITAL MANAGEMENT LLC$14M
- Velan Capital Investment Management LP$2M
- VANGUARD FIDUCIARY TRUST CO$2M
- Opaleye Management Inc.$2M
- DIMENSIONAL FUND ADVISORS LP$959K
- Clearstead Advisors, LLC$801K
Full exits 5
- MWG Caph Ltd$31M
- VANGUARD GROUP INC$25M
- Invesco Ltd.$3M
- JOHNSON & JOHNSON$1M
- Clarius Group, LLC$614K
Largest adds
- MILLENNIUM MANAGEMENT LLC$7M
- SUSQUEHANNA INTERNATIONAL GROUP, LLP$2M
- RENAISSANCE TECHNOLOGIES LLC$1M
- JANE STREET GROUP, LLC$900K
- Qube Research & Technologies Ltd$827K
- MARSHALL WACE, LLP$723K
Largest trims
- ARCH Venture Management, LLC$20M
- GSK plc$16M
- Foresite Capital Management IV, LLC$9M
- Orland Properties Ltd$8M
- Decheng Capital LLC$7M
- Almitas Capital LLC$6M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| ARCH Venture Management, LLC added | 3,247,162 | $65M | 19.4% | 2026-Q1 |
| GSK plc | 1,512,659 | $30M | 9.0% | 2026-Q1 |
| Foresite Capital Management IV, LLC | 800,399 | $16M | 4.8% | 2026-Q1 |
| Orland Properties Ltd | 754,698 | $15M | 4.5% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 718,155 | $14M | 4.3% | 2026-Q1 |
| Decheng Capital LLC | 692,050 | $14M | 4.1% | 2026-Q1 |
| Almitas Capital LLC | 577,807 | $12M | 3.4% | 2026-Q1 |
| Foresite Capital Management V, LLC | 477,078 | $10M | 2.8% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 458,905 | $9M | 2.7% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 381,462 | $8M | 2.3% | 2026-Q1 |
| venBio Partners LLC | 337,697 | $7M | 2.0% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 310,198 | $6M | 1.9% | 2026-Q1 |
| Alphabet Inc. | 293,256 | $6M | 1.8% | 2026-Q1 |
| BlackRock, Inc. added | 191,820 | $4M | 1.1% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 166,980 | $3M | 1.0% | 2026-Q1 |
| MARSHALL WACE, LLP added | 148,516 | $3M | 0.9% | 2026-Q1 |
| RENAISSANCE TECHNOLOGIES LLC added | 116,411 | $2M | 0.7% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 114,491 | $2M | 0.7% | 2026-Q1 |
| Velan Capital Investment Management LP new | 102,000 | $2M | 0.6% | 2026-Q1 |
| MIC Capital Management UK LLP | 87,028 | $2M | 0.5% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 86,925 | $2M | 0.5% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 85,971 | $2M | 0.5% | 2026-Q1 |
| Opaleye Management Inc. trimmed | 79,097 | $2M | 0.5% | 2026-Q1 |
| STATE STREET CORP added | 72,522 | $1M | 0.4% | 2026-Q1 |
| JANE STREET GROUP, LLC added | 63,893 | $1M | 0.4% | 2026-Q1 |
| MORGAN STANLEY added | 56,151 | $1M | 0.3% | 2026-Q1 |
| Qube Research & Technologies Ltd added | 55,110 | $1M | 0.3% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 47,888 | $959K | 0.3% | 2026-Q1 |
| RBF Capital, LLC trimmed | 44,094 | $885K | 0.3% | 2026-Q1 |
| Ikarian Capital, LLC | 41,081 | $824K | 0.2% | 2026-Q1 |
| Clearstead Advisors, LLC new | 39,916 | $801K | 0.2% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 33,321 | $668K | 0.2% | 2026-Q1 |
| UBS Group AG added | 31,814 | $638K | 0.2% | 2026-Q1 |
| NORTHERN TRUST CORP | 30,280 | $607K | 0.2% | 2026-Q1 |
| CANADA PENSION PLAN INVESTMENT BOARD trimmed | 29,411 | $590K | 0.2% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 23,015 | $462K | 0.1% | 2026-Q1 |
| Walleye Capital LLC trimmed | 22,207 | $445K | 0.1% | 2026-Q1 |
| Point72 Asset Management, L.P. added | 21,292 | $427K | 0.1% | 2026-Q1 |
| Susquehanna Portfolio Strategies, LLC | 20,800 | $417K | 0.1% | 2026-Q1 |
| Jump Financial, LLC trimmed | 20,123 | $404K | 0.1% | 2026-Q1 |
| Squarepoint Ops LLC trimmed | 19,294 | $387K | 0.1% | 2026-Q1 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 18,000 | $361K | 0.1% | 2026-Q1 |
| AMERICAN CENTURY COMPANIES INC trimmed | 15,971 | $320K | 0.1% | 2026-Q1 |
| Brevan Howard Capital Management LP trimmed | 13,435 | $270K | 0.1% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 13,128 | $264K | 0.1% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP trimmed | 11,585 | $232K | 0.1% | 2026-Q1 |
| CITIGROUP INC added | 5,912 | $119K | 0.0% | 2026-Q1 |
| Vanguard Global Advisers, LLC new | 5,165 | $104K | 0.0% | 2026-Q1 |
| China Universal Asset Management Co., Ltd. added | 3,770 | $76K | 0.0% | 2026-Q1 |
| HSG Holding Ltd | 152,299 | $73K | 0.0% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS trimmed | 2,097 | $42K | 0.0% | 2026-Q1 |
| FMR LLC trimmed | 1,823 | $37K | 0.0% | 2026-Q1 |
| BARCLAYS PLC trimmed | 1,671 | $34K | 0.0% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 1,468 | $28K | 0.0% | 2026-Q1 |
| Tower Research Capital LLC (TRC) added | 1,301 | $26K | 0.0% | 2026-Q1 |
| Mirae Asset Global Investments Co., Ltd. added | 1,108 | $22K | 0.0% | 2026-Q1 |
| JONES FINANCIAL COMPANIES LLLP | 1,025 | $20K | 0.0% | 2026-Q1 |
| MWG Caph Ltd new | 1,008,116 | $31M | 9.2% | 2025-Q4 stale |
| VANGUARD GROUP INC added | 826,430 | $25M | 7.6% | 2025-Q4 stale |
| MWG Management Ltd. | 1,008,116 | $16M | 4.9% | 2025-Q3 stale |
| Invesco Ltd. added | 98,649 | $3M | 0.9% | 2025-Q4 stale |
| JOHNSON & JOHNSON trimmed | 41,165 | $1M | 0.4% | 2025-Q4 stale |
| TAKEDA PHARMACEUTICAL CO LTD added | 54,887 | $891K | 0.3% | 2025-Q3 stale |
| Woodline Partners LP added | 98,425 | $870K | 0.3% | 2025-Q2 stale |
| ORBIMED ADVISORS LLC | 51,727 | $840K | 0.2% | 2025-Q3 stale |
| Clarius Group, LLC | 19,958 | $614K | 0.2% | 2025-Q4 stale |
| TD Asset Management Inc trimmed | 50,232 | $444K | 0.1% | 2025-Q2 stale |
| JACOBS LEVY EQUITY MANAGEMENT, INC trimmed | 39,621 | $350K | 0.1% | 2025-Q2 stale |
| Nuveen, LLC new | 641,173 | $345K | 0.1% | 2025-Q1 stale |
| BOOTHBAY FUND MANAGEMENT, LLC trimmed | 9,516 | $293K | 0.1% | 2025-Q4 stale |
| Bank of New York Mellon Corp | 525,782 | $283K | 0.1% | 2025-Q1 stale |
| ExodusPoint Capital Management, LP trimmed | 8,511 | $262K | 0.1% | 2025-Q4 stale |
| RAYMOND JAMES FINANCIAL INC | 7,900 | $243K | 0.1% | 2025-Q4 stale |
| Candriam S.C.A. new | 7,617 | $234K | 0.1% | 2025-Q4 stale |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed | 24,419 | $216K | 0.1% | 2025-Q2 stale |
| TWO SIGMA ADVISERS, LP added | 391,200 | $210K | 0.1% | 2025-Q1 stale |
| BBR PARTNERS, LLC trimmed | 6,834 | $210K | 0.1% | 2025-Q4 stale |
| Trexquant Investment LP new | 10,275 | $167K | 0.0% | 2025-Q3 stale |
| Rangeley Capital, LLC | 10,000 | $162K | 0.0% | 2025-Q3 stale |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. trimmed | 295,647 | $159K | 0.0% | 2025-Q1 stale |
| EXCHANGE TRADED CONCEPTS, LLC added | 246,349 | $133K | 0.0% | 2025-Q1 stale |
| RHUMBLINE ADVISERS trimmed | 235,694 | $127K | 0.0% | 2025-Q1 stale |
| ALLIANCEBERNSTEIN L.P. | 220,790 | $119K | 0.0% | 2025-Q1 stale |
| AQR CAPITAL MANAGEMENT LLC added | 174,279 | $94K | 0.0% | 2025-Q1 stale |
| INTECH INVESTMENT MANAGEMENT LLC added | 124,696 | $67K | 0.0% | 2025-Q1 stale |
| TUDOR INVESTMENT CORP ET AL | 124,320 | $67K | 0.0% | 2025-Q1 stale |
| ACADIAN ASSET MANAGEMENT LLC trimmed | 1,657 | $51K | 0.0% | 2025-Q4 stale |
| DEUTSCHE BANK AG\ | 82,441 | $45K | 0.0% | 2025-Q1 stale |
| Corebridge Financial, Inc. trimmed | 78,727 | $42K | 0.0% | 2025-Q1 stale |
| D. E. Shaw & Co., Inc. trimmed | 77,178 | $42K | 0.0% | 2025-Q1 stale |
| SG Americas Securities, LLC trimmed | 71,881 | $39K | 0.0% | 2025-Q1 stale |
| Graham Capital Management, L.P. added | 61,609 | $33K | 0.0% | 2025-Q1 stale |
| SEI INVESTMENTS CO | 55,900 | $30K | 0.0% | 2025-Q1 stale |
| NEW YORK STATE COMMON RETIREMENT FUND | 51,263 | $28K | 0.0% | 2025-Q1 stale |
| VOYA INVESTMENT MANAGEMENT LLC trimmed | 50,329 | $27K | 0.0% | 2025-Q1 stale |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 49,523 | $27K | 0.0% | 2025-Q1 stale |
| PRUDENTIAL FINANCIAL INC | 48,057 | $26K | 0.0% | 2025-Q1 stale |
| ProShare Advisors LLC trimmed | 47,966 | $26K | 0.0% | 2025-Q1 stale |
| CIBC WORLD MARKETS CORP added | 35,658 | $19K | 0.0% | 2025-Q1 stale |
| Police & Firemen's Retirement System of New Jersey | 35,001 | $19K | 0.0% | 2025-Q1 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.