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Institutional Ownership · SEC Form 13F

Who owns Lexicon Pharmaceuticals (LXRX)


Which tracked institutional funds hold LXRX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See LXRX company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

142
Institutional holders
363M
Shares held (tracked funds)
99.3%
Of shares outstanding

How the tape is positioned

28 tracked funds added or opened LXRX while 12 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

LXRX’s largest tracked holder by dollar value, Artal Group S.A., sizes it at 45.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 45.1pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in LXRX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 142 tracked filers holding LXRX, 78 increased or opened the position and 69 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in LXRX between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 3

  • Nuveen, LLC$1M
  • CANADA PENSION PLAN INVESTMENT BOARD$619K
  • DEUTSCHE BANK AG\$594K

Full exits 6

  • JANE STREET GROUP, LLC$4M
  • MARSHALL WACE, LLP$4M
  • GSA CAPITAL PARTNERS LLP$1M
  • Hennion & Walsh Asset Management, Inc.$1M
  • ACADIAN ASSET MANAGEMENT LLC$693K
  • TANG CAPITAL MANAGEMENT LLC$624K

Largest adds

  • Artal Group S.A.$179M
  • FMR LLC$54M
  • Siren, L.L.C.$37M
  • BlackRock, Inc.$36M
  • Sessa Capital IM, L.P.$18M
  • STATE STREET CORP$10M

Largest trims

  • MILLENNIUM MANAGEMENT LLC$5M
  • CIBC Bancorp USA Inc.$3M
  • UBS Group AG$2M
  • SUSQUEHANNA INTERNATIONAL GROUP, LLP$2M
  • GOLDMAN SACHS GROUP INC$505K
  • TWO SIGMA INVESTMENTS, LP$327K

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
Artal Group S.A. added175,156,062$420M48.3%2026-Q2
FMR LLC added51,782,045$124M14.3%2026-Q2
Siren, L.L.C.44,303,518$106M12.2%2026-Q2
Sessa Capital IM, L.P. added18,960,836$46M5.2%2026-Q2
BlackRock, Inc. added17,348,741$42M4.8%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added9,901,208$24M2.7%2026-Q2
Point72 Asset Management, L.P. added8,251,325$20M2.3%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added6,244,372$15M1.7%2026-Q2
STATE STREET CORP added4,917,769$12M1.4%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC added2,357,749$6M0.6%2026-Q2
NORTHERN TRUST CORP added1,968,619$5M0.5%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added1,956,775$5M0.5%2026-Q2
VANGUARD FIDUCIARY TRUST CO added1,634,571$4M0.5%2026-Q2
CITADEL ADVISORS LLC added1,601,182$4M0.4%2026-Q2
Ishara Investments LP added1,271,000$3M0.4%2026-Q2
MILLENNIUM MANAGEMENT LLC trimmed1,134,229$3M0.3%2026-Q2
RENAISSANCE TECHNOLOGIES LLC trimmed1,127,000$3M0.3%2026-Q2
MACKENZIE FINANCIAL CORP added963,354$2M0.3%2026-Q2
ADAR1 Capital Management, LLC750,000$2M0.2%2026-Q2
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed696,776$2M0.2%2026-Q2
UBS Group AG trimmed684,713$2M0.2%2026-Q2
TWO SIGMA INVESTMENTS, LP trimmed643,444$2M0.2%2026-Q2
Nuveen, LLC new586,664$1M0.2%2026-Q2
Bank of New York Mellon Corp added568,706$1M0.2%2026-Q2
Invesco Ltd. trimmed508,071$1M0.1%2026-Q2
GOLDMAN SACHS GROUP INC trimmed485,546$1M0.1%2026-Q2
Compagnie Lombard Odier SCmA trimmed480,000$1M0.1%2026-Q2
BANK OF AMERICA CORP /DE/ trimmed421,299$1M0.1%2026-Q2
BARCLAYS PLC added387,483$930K0.1%2026-Q2
XTX Topco Ltd added357,877$859K0.1%2026-Q2
CANADA PENSION PLAN INVESTMENT BOARD new257,900$619K0.1%2026-Q2
RHUMBLINE ADVISERS added256,885$617K0.1%2026-Q2
DEUTSCHE BANK AG\ added247,528$594K0.1%2026-Q2
WELLS FARGO & COMPANY/MN added230,470$553K0.1%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ added204,391$491K0.1%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP trimmed179,700$431K0.0%2026-Q2
CITIGROUP INC added175,205$420K0.0%2026-Q2
GROUP ONE TRADING LLC trimmed175,013$420K0.0%2026-Q2
Virtus Investment Advisers, LLC trimmed170,415$409K0.0%2026-Q2
Headlands Technologies LLC trimmed167,198$401K0.0%2026-Q2
Ikarian Capital, LLC164,674$395K0.0%2026-Q2
Quarry LP added156,186$375K0.0%2026-Q2
MetLife Investment Management, LLC added146,410$351K0.0%2026-Q2
MORGAN STANLEY trimmed132,902$319K0.0%2026-Q2
PANAGORA ASSET MANAGEMENT INC new132,042$317K0.0%2026-Q2
Aster Capital Management (DIFC) Ltd130,452$123K0.0%2026-Q2
State of Wyoming added119,090$286K0.0%2026-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added114,114$274K0.0%2026-Q2
Cornerstone Investment Partners, LLC new113,739$273K0.0%2026-Q2
JPMORGAN CHASE & CO added109,839$290K0.0%2026-Q2
Cerity Partners LLC trimmed98,400$236K0.0%2026-Q2
ALGERT GLOBAL LLC new92,150$221K0.0%2026-Q2
BANK OF NOVA SCOTIA added86,607$208K0.0%2026-Q2
LPL Financial LLC added84,916$204K0.0%2026-Q2
Vanguard Global Advisers, LLC trimmed77,946$187K0.0%2026-Q2
AQR CAPITAL MANAGEMENT LLC trimmed75,230$181K0.0%2026-Q2
Police & Firemen's Retirement System of New Jersey added73,402$176K0.0%2026-Q2
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO added71,427$171K0.0%2026-Q2
PRUDENTIAL FINANCIAL INC added71,345$171K0.0%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE added69,747$167K0.0%2026-Q2
NEW YORK STATE COMMON RETIREMENT FUND added68,400$164K0.0%2026-Q2
ALLIANCEBERNSTEIN L.P. trimmed67,800$106K0.0%2026-Q2
TWO SIGMA SECURITIES, LLC trimmed66,375$159K0.0%2026-Q2
SEI INVESTMENTS CO new63,937$153K0.0%2026-Q2
Straight Path Wealth Management62,666$150K0.0%2026-Q2
R Squared Ltd trimmed54,985$132K0.0%2026-Q2
Vanguard Personalized Indexing Management, LLC trimmed54,334$130K0.0%2026-Q2
Fortis Group Advisors, LLC50,000$120K0.0%2026-Q2
Schonfeld Strategic Advisors LLC trimmed49,435$119K0.0%2026-Q2
SCOTIA CAPITAL INC. trimmed48,871$117K0.0%2026-Q2
PROFUND ADVISORS LLC new48,586$117K0.0%2026-Q2
VOYA INVESTMENT MANAGEMENT LLC added47,771$115K0.0%2026-Q2
AXQ CAPITAL, LP added45,727$110K0.0%2026-Q2
BOOTHBAY FUND MANAGEMENT, LLC44,315$106K0.0%2026-Q2
WINTON GROUP Ltd added43,200$104K0.0%2026-Q2
INTECH INVESTMENT MANAGEMENT LLC trimmed42,491$102K0.0%2026-Q2
LMR Partners LLP added41,091$99K0.0%2026-Q2
BANK OF MONTREAL /CAN/ trimmed40,000$96K0.0%2026-Q2
BNP PARIBAS FINANCIAL MARKETS added37,780$91K0.0%2026-Q2
Rafferty Asset Management, LLC new34,090$82K0.0%2026-Q2
ProShare Advisors LLC added32,588$78K0.0%2026-Q2
Leonteq Securities AG30,000$72K0.0%2026-Q2
Pathstone Holdings, LLC added29,969$72K0.0%2026-Q2
PINNACLE ASSOCIATES LTD29,015$70K0.0%2026-Q2
VICTORY CAPITAL MANAGEMENT INC added24,223$58K0.0%2026-Q2
Legal & General Group Plc added24,185$58K0.0%2026-Q2
XPONANCE LLC new23,763$57K0.0%2026-Q2
Graham Capital Management, L.P. trimmed23,541$56K0.0%2026-Q2
Ameritas Investment Partners, Inc. added22,986$55K0.0%2026-Q2
D. E. Shaw & Co., Inc. trimmed22,200$53K0.0%2026-Q2
Quadrature Capital Ltd trimmed21,998$53K0.0%2026-Q2
TIAA-CREF INDIVIDUAL & INSTITUTIONAL SERVICES, LLC20,000$48K0.0%2026-Q2
Invera Wealth Advisors, LLC20,000$48K0.0%2026-Q2
DIKER MANAGEMENT LLC20,000$48K0.0%2026-Q2
Russell Investments Group, Ltd. trimmed19,902$48K0.0%2026-Q2
Tower Research Capital LLC (TRC) trimmed19,486$47K0.0%2026-Q2
SBI Securities Co., Ltd. added19,205$46K0.0%2026-Q2
PRINCIPAL FINANCIAL GROUP INC new19,034$46K0.0%2026-Q2
CREDIT AGRICOLE S A18,975$46K0.0%2026-Q2
CAPTRUST FINANCIAL ADVISORS trimmed15,321$37K0.0%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership