Who owns Lexicon Pharmaceuticals (LXRX)
Which tracked institutional funds hold LXRX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See LXRX company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
28 tracked funds added or opened LXRX while 12 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
LXRX’s largest tracked holder by dollar value, Artal Group S.A., sizes it at 45.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 45.1pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in LXRX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 142 tracked filers holding LXRX, 78 increased or opened the position and 69 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in LXRX between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 3
- Nuveen, LLC$1M
- CANADA PENSION PLAN INVESTMENT BOARD$619K
- DEUTSCHE BANK AG\$594K
Full exits 6
- JANE STREET GROUP, LLC$4M
- MARSHALL WACE, LLP$4M
- GSA CAPITAL PARTNERS LLP$1M
- Hennion & Walsh Asset Management, Inc.$1M
- ACADIAN ASSET MANAGEMENT LLC$693K
- TANG CAPITAL MANAGEMENT LLC$624K
Largest adds
- Artal Group S.A.$179M
- FMR LLC$54M
- Siren, L.L.C.$37M
- BlackRock, Inc.$36M
- Sessa Capital IM, L.P.$18M
- STATE STREET CORP$10M
Largest trims
- MILLENNIUM MANAGEMENT LLC$5M
- CIBC Bancorp USA Inc.$3M
- UBS Group AG$2M
- SUSQUEHANNA INTERNATIONAL GROUP, LLP$2M
- GOLDMAN SACHS GROUP INC$505K
- TWO SIGMA INVESTMENTS, LP$327K
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Artal Group S.A. added | 175,156,062 | $420M | 48.3% | 2026-Q2 |
| FMR LLC added | 51,782,045 | $124M | 14.3% | 2026-Q2 |
| Siren, L.L.C. | 44,303,518 | $106M | 12.2% | 2026-Q2 |
| Sessa Capital IM, L.P. added | 18,960,836 | $46M | 5.2% | 2026-Q2 |
| BlackRock, Inc. added | 17,348,741 | $42M | 4.8% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 9,901,208 | $24M | 2.7% | 2026-Q2 |
| Point72 Asset Management, L.P. added | 8,251,325 | $20M | 2.3% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 6,244,372 | $15M | 1.7% | 2026-Q2 |
| STATE STREET CORP added | 4,917,769 | $12M | 1.4% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 2,357,749 | $6M | 0.6% | 2026-Q2 |
| NORTHERN TRUST CORP added | 1,968,619 | $5M | 0.5% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 1,956,775 | $5M | 0.5% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 1,634,571 | $4M | 0.5% | 2026-Q2 |
| CITADEL ADVISORS LLC added | 1,601,182 | $4M | 0.4% | 2026-Q2 |
| Ishara Investments LP added | 1,271,000 | $3M | 0.4% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 1,134,229 | $3M | 0.3% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 1,127,000 | $3M | 0.3% | 2026-Q2 |
| MACKENZIE FINANCIAL CORP added | 963,354 | $2M | 0.3% | 2026-Q2 |
| ADAR1 Capital Management, LLC | 750,000 | $2M | 0.2% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 696,776 | $2M | 0.2% | 2026-Q2 |
| UBS Group AG trimmed | 684,713 | $2M | 0.2% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP trimmed | 643,444 | $2M | 0.2% | 2026-Q2 |
| Nuveen, LLC new | 586,664 | $1M | 0.2% | 2026-Q2 |
| Bank of New York Mellon Corp added | 568,706 | $1M | 0.2% | 2026-Q2 |
| Invesco Ltd. trimmed | 508,071 | $1M | 0.1% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC trimmed | 485,546 | $1M | 0.1% | 2026-Q2 |
| Compagnie Lombard Odier SCmA trimmed | 480,000 | $1M | 0.1% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ trimmed | 421,299 | $1M | 0.1% | 2026-Q2 |
| BARCLAYS PLC added | 387,483 | $930K | 0.1% | 2026-Q2 |
| XTX Topco Ltd added | 357,877 | $859K | 0.1% | 2026-Q2 |
| CANADA PENSION PLAN INVESTMENT BOARD new | 257,900 | $619K | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 256,885 | $617K | 0.1% | 2026-Q2 |
| DEUTSCHE BANK AG\ added | 247,528 | $594K | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 230,470 | $553K | 0.1% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 204,391 | $491K | 0.1% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 179,700 | $431K | 0.0% | 2026-Q2 |
| CITIGROUP INC added | 175,205 | $420K | 0.0% | 2026-Q2 |
| GROUP ONE TRADING LLC trimmed | 175,013 | $420K | 0.0% | 2026-Q2 |
| Virtus Investment Advisers, LLC trimmed | 170,415 | $409K | 0.0% | 2026-Q2 |
| Headlands Technologies LLC trimmed | 167,198 | $401K | 0.0% | 2026-Q2 |
| Ikarian Capital, LLC | 164,674 | $395K | 0.0% | 2026-Q2 |
| Quarry LP added | 156,186 | $375K | 0.0% | 2026-Q2 |
| MetLife Investment Management, LLC added | 146,410 | $351K | 0.0% | 2026-Q2 |
| MORGAN STANLEY trimmed | 132,902 | $319K | 0.0% | 2026-Q2 |
| PANAGORA ASSET MANAGEMENT INC new | 132,042 | $317K | 0.0% | 2026-Q2 |
| Aster Capital Management (DIFC) Ltd | 130,452 | $123K | 0.0% | 2026-Q2 |
| State of Wyoming added | 119,090 | $286K | 0.0% | 2026-Q2 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 114,114 | $274K | 0.0% | 2026-Q2 |
| Cornerstone Investment Partners, LLC new | 113,739 | $273K | 0.0% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 109,839 | $290K | 0.0% | 2026-Q2 |
| Cerity Partners LLC trimmed | 98,400 | $236K | 0.0% | 2026-Q2 |
| ALGERT GLOBAL LLC new | 92,150 | $221K | 0.0% | 2026-Q2 |
| BANK OF NOVA SCOTIA added | 86,607 | $208K | 0.0% | 2026-Q2 |
| LPL Financial LLC added | 84,916 | $204K | 0.0% | 2026-Q2 |
| Vanguard Global Advisers, LLC trimmed | 77,946 | $187K | 0.0% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 75,230 | $181K | 0.0% | 2026-Q2 |
| Police & Firemen's Retirement System of New Jersey added | 73,402 | $176K | 0.0% | 2026-Q2 |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO added | 71,427 | $171K | 0.0% | 2026-Q2 |
| PRUDENTIAL FINANCIAL INC added | 71,345 | $171K | 0.0% | 2026-Q2 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE added | 69,747 | $167K | 0.0% | 2026-Q2 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 68,400 | $164K | 0.0% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. trimmed | 67,800 | $106K | 0.0% | 2026-Q2 |
| TWO SIGMA SECURITIES, LLC trimmed | 66,375 | $159K | 0.0% | 2026-Q2 |
| SEI INVESTMENTS CO new | 63,937 | $153K | 0.0% | 2026-Q2 |
| Straight Path Wealth Management | 62,666 | $150K | 0.0% | 2026-Q2 |
| R Squared Ltd trimmed | 54,985 | $132K | 0.0% | 2026-Q2 |
| Vanguard Personalized Indexing Management, LLC trimmed | 54,334 | $130K | 0.0% | 2026-Q2 |
| Fortis Group Advisors, LLC | 50,000 | $120K | 0.0% | 2026-Q2 |
| Schonfeld Strategic Advisors LLC trimmed | 49,435 | $119K | 0.0% | 2026-Q2 |
| SCOTIA CAPITAL INC. trimmed | 48,871 | $117K | 0.0% | 2026-Q2 |
| PROFUND ADVISORS LLC new | 48,586 | $117K | 0.0% | 2026-Q2 |
| VOYA INVESTMENT MANAGEMENT LLC added | 47,771 | $115K | 0.0% | 2026-Q2 |
| AXQ CAPITAL, LP added | 45,727 | $110K | 0.0% | 2026-Q2 |
| BOOTHBAY FUND MANAGEMENT, LLC | 44,315 | $106K | 0.0% | 2026-Q2 |
| WINTON GROUP Ltd added | 43,200 | $104K | 0.0% | 2026-Q2 |
| INTECH INVESTMENT MANAGEMENT LLC trimmed | 42,491 | $102K | 0.0% | 2026-Q2 |
| LMR Partners LLP added | 41,091 | $99K | 0.0% | 2026-Q2 |
| BANK OF MONTREAL /CAN/ trimmed | 40,000 | $96K | 0.0% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS added | 37,780 | $91K | 0.0% | 2026-Q2 |
| Rafferty Asset Management, LLC new | 34,090 | $82K | 0.0% | 2026-Q2 |
| ProShare Advisors LLC added | 32,588 | $78K | 0.0% | 2026-Q2 |
| Leonteq Securities AG | 30,000 | $72K | 0.0% | 2026-Q2 |
| Pathstone Holdings, LLC added | 29,969 | $72K | 0.0% | 2026-Q2 |
| PINNACLE ASSOCIATES LTD | 29,015 | $70K | 0.0% | 2026-Q2 |
| VICTORY CAPITAL MANAGEMENT INC added | 24,223 | $58K | 0.0% | 2026-Q2 |
| Legal & General Group Plc added | 24,185 | $58K | 0.0% | 2026-Q2 |
| XPONANCE LLC new | 23,763 | $57K | 0.0% | 2026-Q2 |
| Graham Capital Management, L.P. trimmed | 23,541 | $56K | 0.0% | 2026-Q2 |
| Ameritas Investment Partners, Inc. added | 22,986 | $55K | 0.0% | 2026-Q2 |
| D. E. Shaw & Co., Inc. trimmed | 22,200 | $53K | 0.0% | 2026-Q2 |
| Quadrature Capital Ltd trimmed | 21,998 | $53K | 0.0% | 2026-Q2 |
| TIAA-CREF INDIVIDUAL & INSTITUTIONAL SERVICES, LLC | 20,000 | $48K | 0.0% | 2026-Q2 |
| Invera Wealth Advisors, LLC | 20,000 | $48K | 0.0% | 2026-Q2 |
| DIKER MANAGEMENT LLC | 20,000 | $48K | 0.0% | 2026-Q2 |
| Russell Investments Group, Ltd. trimmed | 19,902 | $48K | 0.0% | 2026-Q2 |
| Tower Research Capital LLC (TRC) trimmed | 19,486 | $47K | 0.0% | 2026-Q2 |
| SBI Securities Co., Ltd. added | 19,205 | $46K | 0.0% | 2026-Q2 |
| PRINCIPAL FINANCIAL GROUP INC new | 19,034 | $46K | 0.0% | 2026-Q2 |
| CREDIT AGRICOLE S A | 18,975 | $46K | 0.0% | 2026-Q2 |
| CAPTRUST FINANCIAL ADVISORS trimmed | 15,321 | $37K | 0.0% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.