Who owns LXEO (LXEO)
Which tracked institutional funds hold LXEO, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See LXEO company fundamentals →
Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on LXEO is one-sided between 2025-Q4 and 2026-Q1: 14 added or opened and 53 trimmed or exited — on balance reducing.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
LXEO’s largest tracked holder by dollar value, Paradigm Biocapital Advisors LP, sizes it at 0.7% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.7pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in LXEO divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 138 tracked filers holding LXEO, 78 increased or opened the position and 66 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in LXEO between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 5
- VANGUARD CAPITAL MANAGEMENT LLC$17M
- VANGUARD PORTFOLIO MANAGEMENT LLC$3M
- VANGUARD FIDUCIARY TRUST CO$2M
- Aberdeen Group plc$1M
- ExodusPoint Capital Management, LP$644K
Full exits 11
- VANGUARD GROUP INC$34M
- Siren, L.L.C.$7M
- SILVERARC CAPITAL MANAGEMENT, LLC$6M
- Verition Fund Management LLC$4M
- AMERIPRISE FINANCIAL INC$2M
- RENAISSANCE TECHNOLOGIES LLC$2M
Largest adds
- Spruce Street Capital LP$4M
- GOLDMAN SACHS GROUP INC$3M
- Qube Research & Technologies Ltd$1M
- BANK OF AMERICA CORP /DE/$1M
- MORGAN STANLEY$921K
- Squarepoint Ops LLC$912K
Largest trims
- JANUS HENDERSON GROUP PLC$26M
- Avoro Capital Advisors LLC$22M
- RA CAPITAL MANAGEMENT, L.P.$21M
- BlackRock, Inc.$19M
- Vestal Point Capital, LP$19M
- Frazier Life Sciences Management, L.P.$19M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Paradigm Biocapital Advisors LP added | 6,184,134 | $35M | 6.5% | 2026-Q1 |
| BlackRock, Inc. added | 5,110,871 | $29M | 5.4% | 2026-Q1 |
| Affinity Asset Advisors, LLC added | 5,050,211 | $29M | 5.3% | 2026-Q1 |
| RA CAPITAL MANAGEMENT, L.P. | 5,000,000 | $29M | 5.3% | 2026-Q1 |
| JANUS HENDERSON GROUP PLC trimmed | 4,976,429 | $29M | 5.3% | 2026-Q1 |
| Vestal Point Capital, LP | 4,475,000 | $26M | 4.7% | 2026-Q1 |
| Frazier Life Sciences Management, L.P. | 4,424,725 | $25M | 4.7% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 3,834,999 | $22M | 4.1% | 2026-Q1 |
| ORBIMED ADVISORS LLC added | 3,602,450 | $21M | 3.8% | 2026-Q1 |
| STATE STREET CORP added | 3,568,242 | $20M | 3.8% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 3,007,093 | $17M | 3.2% | 2026-Q1 |
| Woodline Partners LP trimmed | 2,750,532 | $16M | 2.9% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 1,949,885 | $11M | 2.1% | 2026-Q1 |
| Avoro Capital Advisors LLC trimmed | 1,875,000 | $11M | 2.0% | 2026-Q1 |
| Point72 Asset Management, L.P. trimmed | 1,680,449 | $10M | 1.8% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 1,612,780 | $9M | 1.7% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. trimmed | 1,589,585 | $9M | 1.7% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,513,777 | $9M | 1.6% | 2026-Q1 |
| ADAR1 Capital Management, LLC added | 1,467,350 | $8M | 1.6% | 2026-Q1 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 1,250,000 | $7M | 1.3% | 2026-Q1 |
| 683 Capital Management, LLC added | 1,200,000 | $7M | 1.3% | 2026-Q1 |
| Nantahala Capital Management, LLC added | 1,200,000 | $7M | 1.3% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 1,103,584 | $6M | 1.2% | 2026-Q1 |
| Octagon Capital Advisors LP trimmed | 1,100,000 | $6M | 1.2% | 2026-Q1 |
| Spruce Street Capital LP added | 928,593 | $5M | 1.0% | 2026-Q1 |
| Blackstone Inc. | 904,959 | $5M | 1.0% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 577,192 | $3M | 0.6% | 2026-Q1 |
| Ikarian Capital, LLC | 513,011 | $3M | 0.5% | 2026-Q1 |
| NORTHERN TRUST CORP added | 493,666 | $3M | 0.5% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 491,532 | $3M | 0.5% | 2026-Q1 |
| Qube Research & Technologies Ltd added | 465,515 | $3M | 0.5% | 2026-Q1 |
| MORGAN STANLEY added | 402,924 | $2M | 0.4% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 384,734 | $2M | 0.4% | 2026-Q1 |
| DAFNA Capital Management LLC added | 377,059 | $2M | 0.4% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 331,227 | $2M | 0.4% | 2026-Q1 |
| UBS Group AG added | 321,737 | $2M | 0.3% | 2026-Q1 |
| Squarepoint Ops LLC added | 319,090 | $2M | 0.3% | 2026-Q1 |
| Aberdeen Group plc new | 245,904 | $1M | 0.3% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS trimmed | 228,201 | $1M | 0.2% | 2026-Q1 |
| Privium Fund Management B.V. added | 205,000 | $1M | 0.2% | 2026-Q1 |
| Nuveen, LLC trimmed | 182,975 | $1M | 0.2% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed | 182,069 | $1M | 0.2% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP trimmed | 181,676 | $1M | 0.2% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP added | 172,703 | $991K | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp trimmed | 158,899 | $912K | 0.2% | 2026-Q1 |
| Y-Intercept (Hong Kong) Ltd trimmed | 142,571 | $818K | 0.2% | 2026-Q1 |
| BOOTHBAY FUND MANAGEMENT, LLC | 136,377 | $783K | 0.1% | 2026-Q1 |
| Burkehill Global Management, LP | 125,000 | $718K | 0.1% | 2026-Q1 |
| Susquehanna Portfolio Strategies, LLC added | 112,982 | $649K | 0.1% | 2026-Q1 |
| ExodusPoint Capital Management, LP added | 112,172 | $644K | 0.1% | 2026-Q1 |
| ALLIANCEBERNSTEIN L.P. | 61,810 | $614K | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC trimmed | 100,896 | $579K | 0.1% | 2026-Q1 |
| XTX Topco Ltd added | 100,607 | $577K | 0.1% | 2026-Q1 |
| JPMORGAN CHASE & CO added | 93,163 | $491K | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS added | 72,082 | $414K | 0.1% | 2026-Q1 |
| Creative Planning added | 67,079 | $385K | 0.1% | 2026-Q1 |
| Invesco Ltd. trimmed | 63,518 | $365K | 0.1% | 2026-Q1 |
| DEUTSCHE BANK AG\ added | 63,051 | $362K | 0.1% | 2026-Q1 |
| DRW Securities, LLC new | 47,988 | $275K | 0.1% | 2026-Q1 |
| Bleakley Financial Group, LLC new | 47,964 | $275K | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 46,998 | $270K | 0.0% | 2026-Q1 |
| PROFUND ADVISORS LLC added | 45,161 | $259K | 0.0% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 43,132 | $248K | 0.0% | 2026-Q1 |
| Vanguard Global Advisers, LLC new | 42,575 | $244K | 0.0% | 2026-Q1 |
| LOS ANGELES CAPITAL MANAGEMENT LLC added | 37,071 | $213K | 0.0% | 2026-Q1 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added | 37,071 | $209K | 0.0% | 2026-Q1 |
| MetLife Investment Management, LLC trimmed | 35,584 | $204K | 0.0% | 2026-Q1 |
| GSA CAPITAL PARTNERS LLP added | 34,269 | $197K | 0.0% | 2026-Q1 |
| PANAGORA ASSET MANAGEMENT INC | 34,297 | $197K | 0.0% | 2026-Q1 |
| D. E. Shaw & Co., Inc. trimmed | 30,477 | $175K | 0.0% | 2026-Q1 |
| Virtus Investment Advisers, LLC added | 27,910 | $160K | 0.0% | 2026-Q1 |
| VANGUARD GROUP INC added | 3,472,518 | $34M | 6.4% | 2025-Q4 stale |
| Siren, L.L.C. added | 720,622 | $7M | 1.3% | 2025-Q4 stale |
| D1 Capital Partners L.P. | 978,652 | $6M | 1.2% | 2025-Q3 stale |
| SILVERARC CAPITAL MANAGEMENT, LLC trimmed | 617,608 | $6M | 1.1% | 2025-Q4 stale |
| Omega Fund Management, LLC | 1,184,636 | $5M | 0.9% | 2025-Q2 stale |
| Verition Fund Management LLC added | 428,458 | $4M | 0.8% | 2025-Q4 stale |
| Novo Holdings A/S | 1,122,581 | $4M | 0.7% | 2025-Q1 stale |
| Ally Bridge Group (NY) LLC new | 867,302 | $3M | 0.6% | 2025-Q2 stale |
| AMERIPRISE FINANCIAL INC added | 243,294 | $2M | 0.4% | 2025-Q4 stale |
| Avidity Partners Management LP new | 645,000 | $2M | 0.4% | 2025-Q1 stale |
| RENAISSANCE TECHNOLOGIES LLC added | 217,772 | $2M | 0.4% | 2025-Q4 stale |
| JANE STREET GROUP, LLC added | 140,096 | $1M | 0.3% | 2025-Q4 stale |
| PERCEPTIVE ADVISORS LLC | 139,835 | $1M | 0.3% | 2025-Q4 stale |
| Laurion Capital Management LP | 260,228 | $903K | 0.2% | 2025-Q1 stale |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 237,953 | $826K | 0.2% | 2025-Q1 stale |
| TWO SIGMA ADVISERS, LP trimmed | 81,300 | $807K | 0.1% | 2025-Q4 stale |
| Atom Investors LP new | 68,491 | $680K | 0.1% | 2025-Q4 stale |
| ACADIAN ASSET MANAGEMENT LLC added | 50,909 | $505K | 0.1% | 2025-Q4 stale |
| AMERICAN CENTURY COMPANIES INC added | 45,988 | $457K | 0.1% | 2025-Q4 stale |
| Palumbo Wealth Management LLC added | 61,276 | $407K | 0.1% | 2025-Q3 stale |
| Graham Capital Management, L.P. new | 32,898 | $327K | 0.1% | 2025-Q4 stale |
| MARSHALL WACE, LLP added | 81,009 | $281K | 0.1% | 2025-Q1 stale |
| WINTON GROUP Ltd new | 26,900 | $267K | 0.0% | 2025-Q4 stale |
| IEQ CAPITAL, LLC trimmed | 24,692 | $245K | 0.0% | 2025-Q4 stale |
| Pale Fire Capital SE trimmed | 22,302 | $221K | 0.0% | 2025-Q4 stale |
| OMERS ADMINISTRATION Corp new | 20,900 | $208K | 0.0% | 2025-Q4 stale |
| SG Americas Securities, LLC added | 18,640 | $185K | 0.0% | 2025-Q4 stale |
| Persistent Asset Partners Ltd new | 16,025 | $159K | 0.0% | 2025-Q4 stale |
| Shay Capital LLC new | 43,296 | $150K | 0.0% | 2025-Q1 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.