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Institutional Ownership · SEC Form 13F

Who owns LBRX (LBRX)


Which tracked institutional funds hold LBRX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See LBRX company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

77
Institutional holders
28,209,913
Shares held (tracked funds)

How the tape is positioned

The tracked-fund tape on LBRX is one-sided between 2025-Q4 and 2026-Q1: 36 added or opened and 10 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

LBRX’s largest tracked holder by dollar value, Deep Track Capital, LP, sizes it at 1.7% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 1.7pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in LBRX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 77 tracked filers holding LBRX, 51 increased or opened the position and 26 reduced or closed it; over the same quarter, open-market insider Form 4s were net purchases.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in LBRX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 11

  • Caligan Partners LP$35M
  • VANGUARD CAPITAL MANAGEMENT LLC$22M
  • GREAT POINT PARTNERS LLC$7M
  • VANGUARD FIDUCIARY TRUST CO$4M
  • MILLENNIUM MANAGEMENT LLC$3M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$3M

Full exits 3

  • VANGUARD GROUP INC$25M
  • Longbow Finance SA$2M
  • JANE STREET GROUP, LLC$706K

Largest adds

  • Spruce Street Capital LP$11M
  • BlackRock, Inc.$11M
  • Nantahala Capital Management, LLC$11M
  • Nan Fung Group Holdings Ltd$9M
  • Deep Track Capital, LP$8M
  • STATE STREET CORP$7M

Largest trims

  • JENNISON ASSOCIATES LLC$5M
  • Logos Global Management LP$4M
  • JPMORGAN CHASE & CO$3M
  • AMERIPRISE FINANCIAL INC$2M
  • BANK OF AMERICA CORP /DE/$564K
  • BARCLAYS PLC$561K

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
Deep Track Capital, LP3,352,804$83M11.3%2026-Q1
BlackRock, Inc. added2,470,845$61M8.3%2026-Q1
RA CAPITAL MANAGEMENT, L.P.2,208,604$54M7.5%2026-Q1
TCG Crossover Management, LLC added1,839,489$45M6.2%2026-Q1
Commodore Capital LP1,500,000$37M5.1%2026-Q1
Caligan Partners LP new1,438,070$35M4.7%2026-Q1
Spruce Street Capital LP added1,376,159$34M4.6%2026-Q1
JPMORGAN CHASE & CO trimmed1,427,568$33M4.5%2026-Q1
Trails Edge Capital Partners, LP trimmed1,319,362$33M4.5%2026-Q1
Nantahala Capital Management, LLC added1,052,894$26M3.6%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. added923,694$23M3.1%2026-Q1
Logos Global Management LP trimmed915,000$23M3.1%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new894,653$22M3.0%2026-Q1
Alyeska Investment Group, L.P. added863,947$21M2.9%2026-Q1
Vivo Capital, LLC800,000$20M2.7%2026-Q1
Nan Fung Group Holdings Ltd added630,657$16M2.1%2026-Q1
JENNISON ASSOCIATES LLC trimmed538,216$13M1.8%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added518,228$13M1.7%2026-Q1
STATE STREET CORP added504,373$12M1.7%2026-Q1
CITADEL ADVISORS LLC added416,906$10M1.4%2026-Q1
GOLDMAN SACHS GROUP INC added363,799$9M1.2%2026-Q1
GREAT POINT PARTNERS LLC new300,000$7M1.0%2026-Q1
FMR LLC added222,508$5M0.8%2026-Q1
BAKER BROS. ADVISORS LP200,000$5M0.7%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added186,095$5M0.6%2026-Q1
HighVista Strategies LLC added173,595$4M0.6%2026-Q1
VANGUARD FIDUCIARY TRUST CO new157,426$4M0.5%2026-Q1
NORTHERN TRUST CORP added154,398$4M0.5%2026-Q1
Integral Health Asset Management, LLC added150,000$4M0.5%2026-Q1
UBS Group AG added137,932$3M0.5%2026-Q1
MILLENNIUM MANAGEMENT LLC trimmed136,966$3M0.5%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new112,497$3M0.4%2026-Q1
AMERIPRISE FINANCIAL INC trimmed108,307$3M0.4%2026-Q1
Eversept Partners, LP new100,198$2M0.3%2026-Q1
Russell Investments Group, Ltd. added72,067$2M0.2%2026-Q1
Boxer Capital Management, LLC70,000$2M0.2%2026-Q1
JANUS HENDERSON GROUP PLC new65,429$2M0.2%2026-Q1
WELLINGTON MANAGEMENT GROUP LLP trimmed52,640$1M0.2%2026-Q1
STEMPOINT CAPITAL LP new50,000$1M0.2%2026-Q1
MORGAN STANLEY added47,280$1M0.2%2026-Q1
Bank of New York Mellon Corp added45,457$1M0.2%2026-Q1
ACUTA CAPITAL PARTNERS, LLC trimmed28,919$713K0.1%2026-Q1
Calamos Advisors LLC new24,063$593K0.1%2026-Q1
Nuveen, LLC22,966$566K0.1%2026-Q1
Focus Partners Wealth trimmed19,815$489K0.1%2026-Q1
RHUMBLINE ADVISERS added17,103$422K0.1%2026-Q1
BANK OF AMERICA CORP /DE/ trimmed16,618$410K0.1%2026-Q1
DEUTSCHE BANK AG\ added15,359$379K0.1%2026-Q1
MEYER HANDELMAN CO new15,094$372K0.1%2026-Q1
Opaleye Management Inc. new14,506$358K0.0%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ added13,229$327K0.0%2026-Q1
TWO SIGMA INVESTMENTS, LP12,720$314K0.0%2026-Q1
MetLife Investment Management, LLC11,104$274K0.0%2026-Q1
Invesco Ltd. trimmed10,729$265K0.0%2026-Q1
Soleus Capital Management, L.P.10,000$247K0.0%2026-Q1
Quadrature Capital Ltd new9,931$245K0.0%2026-Q1
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added9,170$226K0.0%2026-Q1
Vanguard Global Advisers, LLC new8,753$216K0.0%2026-Q1
WELLS FARGO & COMPANY/MN trimmed8,623$213K0.0%2026-Q1
NEW YORK STATE COMMON RETIREMENT FUND new6,100$150K0.0%2026-Q1
Police & Firemen's Retirement System of New Jersey added6,041$149K0.0%2026-Q1
CITIGROUP INC added5,569$137K0.0%2026-Q1
STRS OHIO added5,100$126K0.0%2026-Q1
FEDERATED HERMES, INC.5,000$123K0.0%2026-Q1
BARCLAYS PLC trimmed4,530$112K0.0%2026-Q1
BNP PARIBAS FINANCIAL MARKETS added4,052$100K0.0%2026-Q1
Legal & General Group Plc trimmed1,723$42K0.0%2026-Q1
Tower Research Capital LLC (TRC) added1,661$41K0.0%2026-Q1
Ameritas Investment Partners, Inc.1,562$39K0.0%2026-Q1
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM trimmed1,041$26K0.0%2026-Q1
Sterling Capital Management LLC trimmed368$9K0.0%2026-Q1
GAMMA Investing LLC added162$4K0.0%2026-Q1
PNC FINANCIAL SERVICES GROUP, INC. new145$4K0.0%2026-Q1
MassMutual Private Wealth & Trust, FSB new54$1K0.0%2026-Q1
CWM, LLC added29$7150.0%2026-Q1
VANGUARD GROUP INC new1,112,978$25M3.4%2025-Q4 stale
ADAGE CAPITAL PARTNERS GP, L.L.C. new200,000$3M0.4%2025-Q3 stale
Longbow Finance SA new82,336$2M0.3%2025-Q4 stale
SILVERARC CAPITAL MANAGEMENT, LLC new70,000$1M0.2%2025-Q3 stale
HRT FINANCIAL LP new58,815$928K0.1%2025-Q3 stale
JANE STREET GROUP, LLC added31,733$706K0.1%2025-Q4 stale
Monashee Investment Management LLC new40,000$632K0.1%2025-Q3 stale
TD Asset Management Inc new36,780$581K0.1%2025-Q3 stale
Point72 (DIFC) Ltd new34,003$537K0.1%2025-Q3 stale
NORGES BANK new20,000$445K0.1%2025-Q4 stale
Hudson Bay Capital Management LP27,097$428K0.1%2025-Q4 stale
XTX Topco Ltd added19,121$426K0.1%2025-Q4 stale
MARSHALL WACE, LLP trimmed18,014$401K0.1%2025-Q4 stale
Squarepoint Ops LLC new20,825$329K0.0%2025-Q3 stale
Jefferies Financial Group Inc. trimmed12,445$277K0.0%2025-Q4 stale
MANUFACTURERS LIFE INSURANCE COMPANY, THE new17,488$276K0.0%2025-Q3 stale
ARISTEIA CAPITAL, L.L.C. new15,270$241K0.0%2025-Q3 stale
Point72 Asia (Singapore) Pte. Ltd. new14,535$230K0.0%2025-Q3 stale
Quantessence Capital LLC new14,225$225K0.0%2025-Q3 stale
Brevan Howard Capital Management LP new13,259$209K0.0%2025-Q3 stale
LANDSCAPE CAPITAL MANAGEMENT, L.L.C. new10,638$168K0.0%2025-Q3 stale
SG Americas Securities, LLC new6,434$143K0.0%2025-Q4 stale
Persistent Asset Partners Ltd new4,080$91K0.0%2025-Q4 stale
ROYAL BANK OF CANADA new767$17K0.0%2025-Q4 stale
AMALGAMATED BANK new605$13K0.0%2025-Q4 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership