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Institutional Ownership · SEC Form 13F

Who owns Krystal Biotech (KRYS)


Which tracked institutional funds hold KRYS, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See KRYS company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

391
Institutional holders
29M
Shares held (tracked funds)

How the tape is positioned

The tracked-fund tape on KRYS is one-sided between 2026-Q1 and 2026-Q2: 184 added or opened and 46 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

KRYS’s largest tracked holder by dollar value, FMR LLC, sizes it at 0.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in KRYS divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 391 tracked filers holding KRYS, 254 increased or opened the position and 164 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in KRYS between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 23

  • Jupiter Topco LLC$95M
  • WESTFIELD CAPITAL MANAGEMENT CO LP$37M
  • CONGRESS ASSET MANAGEMENT CO$15M
  • Life Cycle Investment Partners Ltd$13M
  • VAN ECK ASSOCIATES CORP$6M
  • Mediolanum International Funds Ltd$6M

Full exits 31

  • JANUS HENDERSON GROUP PLC$69M
  • Handelsbanken Fonder AB$24M
  • MARSHALL WACE, LLP$18M
  • C WorldWide Group Holding A/S$18M
  • CANADA LIFE ASSURANCE Co$6M
  • BESSEMER GROUP INC$5M

Largest adds

  • BlackRock, Inc.$627M
  • FMR LLC$514M
  • Avoro Capital Advisors LLC$327M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$209M
  • STATE STREET CORP$163M
  • VANGUARD CAPITAL MANAGEMENT LLC$160M

Largest trims

  • Bellevue Group AG$96M
  • TD Asset Management Inc$3M
  • CASTLEARK MANAGEMENT LLC$2M
  • SUSQUEHANNA INTERNATIONAL GROUP, LLP$2M
  • XTX Topco Ltd$2M
  • Rafferty Asset Management, LLC$1M

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
FMR LLC added4,418,197$1.6B15.5%2026-Q2
BlackRock, Inc. added4,181,432$1.6B14.7%2026-Q2
Avoro Capital Advisors LLC2,888,888$1.1B10.1%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC added1,574,905$585M5.5%2026-Q2
STATE STREET CORP added1,351,158$502M4.7%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added1,240,567$461M4.3%2026-Q2
Soleus Capital Management, L.P. trimmed939,254$349M3.3%2026-Q2
Capital World Investors trimmed777,843$289M2.7%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added698,993$260M2.5%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ added687,400$255M2.4%2026-Q2
Hood River Capital Management LLC added663,375$247M2.3%2026-Q2
Redmile Group, LLC trimmed632,005$235M2.2%2026-Q2
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC added570,153$212M2.0%2026-Q2
Frazier Life Sciences Management, L.P.481,307$179M1.7%2026-Q2
DIMENSIONAL FUND ADVISORS LP added476,038$177M1.7%2026-Q2
FIRST TRUST ADVISORS LP trimmed324,900$121M1.1%2026-Q2
Invesco Ltd. added324,755$121M1.1%2026-Q2
GOLDMAN SACHS GROUP INC added298,841$111M1.0%2026-Q2
NORTHERN TRUST CORP added283,784$105M1.0%2026-Q2
FRANKLIN RESOURCES INC added261,917$97M0.9%2026-Q2
NORGES BANK trimmed259,030$96M0.9%2026-Q2
Jupiter Topco LLC new256,665$95M0.9%2026-Q2
BANK OF AMERICA CORP /DE/ trimmed256,431$95M0.9%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added254,828$95M0.9%2026-Q2
MORGAN STANLEY added235,491$88M0.8%2026-Q2
VANGUARD FIDUCIARY TRUST CO added189,528$70M0.7%2026-Q2
PRINCIPAL FINANCIAL GROUP INC added169,550$63M0.6%2026-Q2
Bank of New York Mellon Corp added163,610$61M0.6%2026-Q2
RAYMOND JAMES FINANCIAL INC added158,675$59M0.6%2026-Q2
Woodline Partners LP150,616$56M0.5%2026-Q2
UBS Group AG added148,316$55M0.5%2026-Q2
Nuveen, LLC added146,520$54M0.5%2026-Q2
BRAIDWELL LP trimmed128,975$48M0.5%2026-Q2
VOYA INVESTMENT MANAGEMENT LLC added124,442$46M0.4%2026-Q2
TimesSquare Capital Management, LLC trimmed111,545$41M0.4%2026-Q2
Pictet Asset Management Holding SA trimmed107,798$40M0.4%2026-Q2
Public Sector Pension Investment Board added105,515$39M0.4%2026-Q2
1832 Asset Management L.P. added99,300$37M0.3%2026-Q2
WESTFIELD CAPITAL MANAGEMENT CO LP new98,707$37M0.3%2026-Q2
BNP PARIBAS FINANCIAL MARKETS trimmed92,234$34M0.3%2026-Q2
JPMORGAN CHASE & CO trimmed87,342$33M0.3%2026-Q2
ORBIMED ADVISORS LLC added83,200$31M0.3%2026-Q2
S SQUARED TECHNOLOGY, LLC trimmed77,545$29M0.3%2026-Q2
Bellevue Group AG trimmed77,530$29M0.3%2026-Q2
Biondo Investment Advisors, LLC trimmed70,945$26M0.2%2026-Q2
SEGALL BRYANT & HAMILL, LLC trimmed65,211$24M0.2%2026-Q2
RHUMBLINE ADVISERS trimmed61,236$23M0.2%2026-Q2
RENAISSANCE TECHNOLOGIES LLC added59,680$22M0.2%2026-Q2
Legal & General Group Plc trimmed58,580$22M0.2%2026-Q2
CITIGROUP INC added56,016$21M0.2%2026-Q2
Bridgewater Associates, LP added54,489$20M0.2%2026-Q2
SEI INVESTMENTS CO added54,040$20M0.2%2026-Q2
Russell Investments Group, Ltd. added52,621$20M0.2%2026-Q2
Allspring Global Investments Holdings, LLC added52,407$19M0.2%2026-Q2
NEUBERGER BERMAN GROUP LLC added51,876$19M0.2%2026-Q2
AMERIPRISE FINANCIAL INC trimmed48,790$18M0.2%2026-Q2
Palisades Investment Partners, LLC added47,801$18M0.2%2026-Q2
ACT CAPITAL MANAGEMENT, LLC trimmed45,000$17M0.2%2026-Q2
VICTORY CAPITAL MANAGEMENT INC added44,935$17M0.2%2026-Q2
FEDERATED HERMES, INC. added43,848$16M0.2%2026-Q2
Swiss National Bank trimmed41,360$15M0.1%2026-Q2
GILDER GAGNON HOWE & CO LLC added40,296$15M0.1%2026-Q2
CONGRESS ASSET MANAGEMENT CO new40,134$15M0.1%2026-Q2
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added38,697$14M0.1%2026-Q2
SEB Asset Management AB trimmed37,731$14M0.1%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP added36,936$14M0.1%2026-Q2
Life Cycle Investment Partners Ltd new35,124$13M0.1%2026-Q2
WELLS FARGO & COMPANY/MN added34,502$13M0.1%2026-Q2
ALLIANCEBERNSTEIN L.P. added34,039$9M0.1%2026-Q2
NEW YORK STATE COMMON RETIREMENT FUND added34,033$13M0.1%2026-Q2
Granite Investment Partners, LLC added32,837$12M0.1%2026-Q2
PRUDENTIAL FINANCIAL INC added32,662$12M0.1%2026-Q2
Corient Private Wealth LP added32,580$12M0.1%2026-Q2
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC trimmed31,998$12M0.1%2026-Q2
DEUTSCHE BANK AG\ added31,836$12M0.1%2026-Q2
Fisher Asset Management, LLC trimmed27,676$10M0.1%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed25,867$10M0.1%2026-Q2
Aberdeen Group plc trimmed25,141$9M0.1%2026-Q2
Atle Fund Management AB trimmed24,019$9M0.1%2026-Q2
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM trimmed23,692$9M0.1%2026-Q2
TD Asset Management Inc trimmed22,712$8M0.1%2026-Q2
Elmind Capital, LP22,000$8M0.1%2026-Q2
VANGUARD ASSET MANAGEMENT, Ltd added21,390$8M0.1%2026-Q2
Creative Planning added20,318$8M0.1%2026-Q2
Pinnacle Financial Partners, Inc. added20,243$8M0.1%2026-Q2
Tetragon Partners GP Ltd19,668$7M0.1%2026-Q2
Lisanti Capital Growth, LLC added19,050$7M0.1%2026-Q2
VAN ECK ASSOCIATES CORP new17,071$6M0.1%2026-Q2
ADAR1 Capital Management, LLC trimmed16,420$6M0.1%2026-Q2
Cinctive Capital Management LP added16,367$6M0.1%2026-Q2
Rhenman & Partners Asset Management AB trimmed16,325$6M0.1%2026-Q2
Informed Momentum Co LLC trimmed16,227$6M0.1%2026-Q2
CASTLEARK MANAGEMENT LLC trimmed16,150$6M0.1%2026-Q2
Mediolanum International Funds Ltd new15,940$6M0.1%2026-Q2
WCM INVESTMENT MANAGEMENT, LLC new15,753$6M0.1%2026-Q2
CIM, LLC added15,703$6M0.1%2026-Q2
EFG International AG trimmed15,304$6M0.1%2026-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added15,297$6M0.1%2026-Q2
MetLife Investment Management, LLC added15,196$6M0.1%2026-Q2
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM trimmed14,483$5M0.1%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership