Who owns Ionis Pharmaceuticals (IONS)
Which tracked institutional funds hold IONS, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See IONS company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
152 tracked funds added or opened IONS while 103 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
IONS’s largest tracked holder by dollar value, FMR LLC, sizes it at 0.1% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 0.0pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in IONS divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 483 tracked filers holding IONS, 245 increased or opened the position and 234 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in IONS between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 21
- Capital International Investors$65M
- Freestone Grove Partners LP$27M
- Life Cycle Investment Partners Ltd$17M
- Eagle Health Investments LP$15M
- PICTON MAHONEY ASSET MANAGEMENT$8M
- BANK OF NOVA SCOTIA$5M
Full exits 39
- T. Rowe Price Investment Management, Inc.$462M
- GW&K Investment Management, LLC$59M
- C WorldWide Group Holding A/S$27M
- HRT FINANCIAL LP$19M
- Zurich Insurance Group Ltd/FI$18M
- Handelsbanken Fonder AB$16M
Largest adds
- ROYAL BANK OF CANADA$205M
- BlackRock, Inc.$191M
- WELLINGTON MANAGEMENT GROUP LLP$127M
- Capital World Investors$127M
- FMR LLC$109M
- BARCLAYS PLC$105M
Largest trims
- Bellevue Group AG$59M
- MILLENNIUM MANAGEMENT LLC$56M
- CITADEL ADVISORS LLC$52M
- AMERIPRISE FINANCIAL INC$44M
- Squarepoint Ops LLC$44M
- SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC$43M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| FMR LLC added | 24,631,956 | $2.0B | 14.9% | 2026-Q2 |
| Capital World Investors added | 21,669,226 | $1.7B | 13.1% | 2026-Q2 |
| BlackRock, Inc. added | 10,704,660 | $849M | 6.5% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 7,859,529 | $623M | 4.7% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP added | 7,651,415 | $607M | 4.6% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 7,211,497 | $572M | 4.4% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP added | 6,252,342 | $496M | 3.8% | 2026-Q2 |
| ROYAL BANK OF CANADA added | 6,182,479 | $490M | 3.7% | 2026-Q2 |
| STATE STREET CORP added | 4,334,848 | $344M | 2.6% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC trimmed | 3,584,024 | $295M | 2.2% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 3,184,500 | $252M | 1.9% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 2,671,717 | $216M | 1.6% | 2026-Q2 |
| Artisan Partners Limited Partnership added | 2,640,024 | $209M | 1.6% | 2026-Q2 |
| Tweedy, Browne Co LLC added | 2,280,311 | $181M | 1.4% | 2026-Q2 |
| Deep Track Capital, LP added | 2,200,000 | $174M | 1.3% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 2,109,945 | $167M | 1.3% | 2026-Q2 |
| BAKER BROS. ADVISORS LP | 2,047,727 | $162M | 1.2% | 2026-Q2 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,979,669 | $157M | 1.2% | 2026-Q2 |
| AMERICAN CENTURY COMPANIES INC added | 1,947,076 | $154M | 1.2% | 2026-Q2 |
| FRANKLIN RESOURCES INC added | 1,623,377 | $129M | 1.0% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 1,605,054 | $127M | 1.0% | 2026-Q2 |
| BARCLAYS PLC added | 1,603,136 | $127M | 1.0% | 2026-Q2 |
| Pictet Asset Management Holding SA added | 1,596,998 | $127M | 1.0% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 1,454,672 | $115M | 0.9% | 2026-Q2 |
| Polar Capital Holdings Plc added | 1,454,021 | $115M | 0.9% | 2026-Q2 |
| Alyeska Investment Group, L.P. added | 1,417,916 | $112M | 0.9% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. added | 1,300,392 | $103M | 0.8% | 2026-Q2 |
| MORGAN STANLEY added | 1,281,444 | $102M | 0.8% | 2026-Q2 |
| Invesco Ltd. trimmed | 1,120,707 | $89M | 0.7% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 1,060,845 | $84M | 0.6% | 2026-Q2 |
| Bellevue Group AG trimmed | 972,258 | $77M | 0.6% | 2026-Q2 |
| GROUPAMA ASSET MANAGMENT added | 937,083 | $75M | 0.6% | 2026-Q2 |
| NORTHERN TRUST CORP added | 913,610 | $72M | 0.6% | 2026-Q2 |
| Capital International Investors new | 823,764 | $65M | 0.5% | 2026-Q2 |
| Davern Capital Partners, LP added | 798,709 | $63M | 0.5% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ trimmed | 790,990 | $63M | 0.5% | 2026-Q2 |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC trimmed | 787,263 | $62M | 0.5% | 2026-Q2 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. trimmed | 734,219 | $58M | 0.4% | 2026-Q2 |
| Nuveen, LLC added | 726,282 | $58M | 0.4% | 2026-Q2 |
| Connor, Clark & Lunn Investment Management Ltd. trimmed | 684,236 | $54M | 0.4% | 2026-Q2 |
| Eversept Partners, LP added | 664,684 | $53M | 0.4% | 2026-Q2 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 655,454 | $52M | 0.4% | 2026-Q2 |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ trimmed | 651,816 | $52M | 0.4% | 2026-Q2 |
| NEUBERGER BERMAN GROUP LLC added | 633,533 | $50M | 0.4% | 2026-Q2 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP trimmed | 632,028 | $50M | 0.4% | 2026-Q2 |
| UBS Group AG trimmed | 624,874 | $50M | 0.4% | 2026-Q2 |
| TimesSquare Capital Management, LLC added | 614,070 | $49M | 0.4% | 2026-Q2 |
| EVENTIDE ASSET MANAGEMENT, LLC | 575,000 | $46M | 0.3% | 2026-Q2 |
| PERCEPTIVE ADVISORS LLC added | 566,000 | $45M | 0.3% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC added | 559,414 | $44M | 0.3% | 2026-Q2 |
| Bank of New York Mellon Corp added | 542,454 | $43M | 0.3% | 2026-Q2 |
| TEACHER RETIREMENT SYSTEM OF TEXAS trimmed | 522,317 | $41M | 0.3% | 2026-Q2 |
| BOONE CAPITAL MANAGEMENT LLC added | 519,977 | $41M | 0.3% | 2026-Q2 |
| JANE STREET GROUP, LLC added | 503,647 | $40M | 0.3% | 2026-Q2 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 500,050 | $40M | 0.3% | 2026-Q2 |
| BNP PARIBAS FINANCIAL MARKETS trimmed | 454,649 | $36M | 0.3% | 2026-Q2 |
| Candriam S.C.A. trimmed | 445,019 | $35M | 0.3% | 2026-Q2 |
| FIRST TRUST ADVISORS LP trimmed | 427,197 | $34M | 0.3% | 2026-Q2 |
| PINNACLE ASSOCIATES LTD trimmed | 419,752 | $33M | 0.3% | 2026-Q2 |
| NOMURA HOLDINGS INC added | 402,192 | $32M | 0.2% | 2026-Q2 |
| TD Asset Management Inc trimmed | 340,548 | $27M | 0.2% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. trimmed | 340,450 | $26M | 0.2% | 2026-Q2 |
| Freestone Grove Partners LP new | 339,967 | $27M | 0.2% | 2026-Q2 |
| Qube Research & Technologies Ltd added | 333,952 | $26M | 0.2% | 2026-Q2 |
| Capital Research Global Investors added | 331,936 | $26M | 0.2% | 2026-Q2 |
| CAPITAL FUND MANAGEMENT S.A. added | 329,554 | $26M | 0.2% | 2026-Q2 |
| Carmignac Gestion added | 321,000 | $25M | 0.2% | 2026-Q2 |
| Privium Fund Management B.V. added | 319,924 | $25M | 0.2% | 2026-Q2 |
| Swiss National Bank added | 315,000 | $25M | 0.2% | 2026-Q2 |
| Jump Financial, LLC added | 306,330 | $24M | 0.2% | 2026-Q2 |
| ARK Investment Management LLC added | 300,770 | $24M | 0.2% | 2026-Q2 |
| Legal & General Group Plc added | 299,184 | $24M | 0.2% | 2026-Q2 |
| D. E. Shaw & Co., Inc. trimmed | 297,041 | $24M | 0.2% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 288,872 | $23M | 0.2% | 2026-Q2 |
| DAVENPORT & Co LLC added | 283,960 | $23M | 0.2% | 2026-Q2 |
| Aberdeen Group plc added | 277,400 | $22M | 0.2% | 2026-Q2 |
| California Public Employees Retirement System added | 270,843 | $21M | 0.2% | 2026-Q2 |
| TOCQUEVILLE ASSET MANAGEMENT L.P. added | 251,215 | $20M | 0.2% | 2026-Q2 |
| RAYMOND JAMES FINANCIAL INC added | 237,348 | $19M | 0.1% | 2026-Q2 |
| CITADEL ADVISORS LLC trimmed | 236,284 | $19M | 0.1% | 2026-Q2 |
| Universal- Beteiligungs- und Servicegesellschaft mbH added | 233,499 | $19M | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 226,213 | $18M | 0.1% | 2026-Q2 |
| Empowered Funds, LLC added | 223,142 | $18M | 0.1% | 2026-Q2 |
| Orion Investment Co trimmed | 220,335 | $17M | 0.1% | 2026-Q2 |
| Life Cycle Investment Partners Ltd new | 219,896 | $17M | 0.1% | 2026-Q2 |
| ALGERT GLOBAL LLC added | 206,853 | $16M | 0.1% | 2026-Q2 |
| STIFEL FINANCIAL CORP added | 202,983 | $16M | 0.1% | 2026-Q2 |
| Corient Private Wealth LP added | 196,791 | $16M | 0.1% | 2026-Q2 |
| Eagle Health Investments LP new | 194,577 | $15M | 0.1% | 2026-Q2 |
| SECTOR GAMMA AS added | 189,468 | $15M | 0.1% | 2026-Q2 |
| HSBC HOLDINGS PLC added | 188,402 | $15M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 180,949 | $14M | 0.1% | 2026-Q2 |
| Polymer Capital Management (HK) LTD added | 177,897 | $14M | 0.1% | 2026-Q2 |
| DEUTSCHE BANK AG\ added | 169,614 | $13M | 0.1% | 2026-Q2 |
| ADAR1 Capital Management, LLC added | 166,286 | $13M | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS trimmed | 164,911 | $13M | 0.1% | 2026-Q2 |
| Sicart Associates LLC added | 160,694 | $13M | 0.1% | 2026-Q2 |
| VANGUARD ASSET MANAGEMENT, Ltd added | 155,088 | $12M | 0.1% | 2026-Q2 |
| CSS LLC/IL added | 152,289 | $12M | 0.1% | 2026-Q2 |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main trimmed | 151,301 | $12M | 0.1% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.