Who owns Structure Therapeutics (GPCR)
Which tracked institutional funds hold GPCR, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See GPCR company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
82 tracked funds added or opened GPCR while 45 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
GPCR’s largest tracked holder by dollar value, FMR LLC, sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes GPCR more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in GPCR divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 184 tracked filers holding GPCR, 100 increased or opened the position and 168 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in GPCR between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 10
- Jupiter Topco LLC$279M
- RTW INVESTMENTS, LP$86M
- ExodusPoint Capital Management, LP$4M
- ADAGE CAPITAL PARTNERS GP, L.L.C.$4M
- Y-Intercept (Hong Kong) Ltd$1M
- NOMURA HOLDINGS INC$1M
Full exits 22
- Exor N.V.$5.0B
- Paradigm Biocapital Advisors LP$26M
- BALYASNY ASSET MANAGEMENT L.P.$15M
- Pentwater Capital Management LP$12M
- Sio Capital Management, LLC$10M
- Holocene Advisors, LP$8M
Largest adds
- Deep Track Capital, LP$48M
- WELLINGTON MANAGEMENT GROUP LLP$47M
- MORGAN STANLEY$40M
- Avoro Capital Advisors LLC$36M
- ORBIMED ADVISORS LLC$25M
- DEERFIELD MANAGEMENT COMPANY, L.P.$21M
Largest trims
- PRICE T ROWE ASSOCIATES INC /MD/$51M
- Siren, L.L.C.$17M
- ALLIANCEBERNSTEIN L.P.$15M
- JPMORGAN CHASE & CO$9M
- STEMPOINT CAPITAL LP$8M
- VOLORIDGE INVESTMENT MANAGEMENT, LLC$6M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| FMR LLC trimmed | 7,810,306 | $419M | 11.7% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP added | 7,379,433 | $396M | 11.0% | 2026-Q2 |
| Avoro Capital Advisors LLC | 6,555,555 | $352M | 9.8% | 2026-Q2 |
| Jupiter Topco LLC new | 5,204,212 | $279M | 7.8% | 2026-Q2 |
| Deep Track Capital, LP added | 4,740,072 | $254M | 7.1% | 2026-Q2 |
| BVF INC/IL trimmed | 3,366,823 | $181M | 5.0% | 2026-Q2 |
| MORGAN STANLEY added | 2,806,640 | $151M | 4.2% | 2026-Q2 |
| ORBIMED ADVISORS LLC added | 2,209,400 | $119M | 3.3% | 2026-Q2 |
| PRINCIPAL FINANCIAL GROUP INC trimmed | 1,752,753 | $94M | 2.6% | 2026-Q2 |
| AMERICAN CENTURY COMPANIES INC added | 1,682,179 | $90M | 2.5% | 2026-Q2 |
| RTW INVESTMENTS, LP added | 1,607,507 | $86M | 2.4% | 2026-Q2 |
| Driehaus Capital Management LLC trimmed | 1,553,219 | $83M | 2.3% | 2026-Q2 |
| BAKER BROS. ADVISORS LP | 1,432,529 | $77M | 2.1% | 2026-Q2 |
| Casdin Capital, LLC | 1,175,000 | $63M | 1.8% | 2026-Q2 |
| DEERFIELD MANAGEMENT COMPANY, L.P. added | 1,086,000 | $58M | 1.6% | 2026-Q2 |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC trimmed | 1,041,100 | $56M | 1.6% | 2026-Q2 |
| Siren, L.L.C. trimmed | 872,967 | $47M | 1.3% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ trimmed | 845,532 | $45M | 1.3% | 2026-Q2 |
| Pacific Heights Asset Management LLC added | 800,000 | $43M | 1.2% | 2026-Q2 |
| Rock Springs Capital Management LP added | 640,317 | $34M | 1.0% | 2026-Q2 |
| Aberdeen Group plc added | 639,915 | $34M | 1.0% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. trimmed | 611,708 | $29M | 0.8% | 2026-Q2 |
| FRANKLIN RESOURCES INC added | 578,839 | $31M | 0.9% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 563,422 | $30M | 0.8% | 2026-Q2 |
| BlackRock, Inc. added | 511,149 | $27M | 0.8% | 2026-Q2 |
| Logos Global Management LP | 500,000 | $27M | 0.7% | 2026-Q2 |
| Parkman Healthcare Partners LLC added | 485,661 | $26M | 0.7% | 2026-Q2 |
| Davern Capital Partners, LP added | 446,059 | $24M | 0.7% | 2026-Q2 |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND trimmed | 418,800 | $22M | 0.6% | 2026-Q2 |
| UBS Group AG added | 378,986 | $20M | 0.6% | 2026-Q2 |
| DEUTSCHE BANK AG\ | 331,867 | $18M | 0.5% | 2026-Q2 |
| NEXTBio Capital Management LP added | 312,496 | $17M | 0.5% | 2026-Q2 |
| Catalio Capital Management, LP added | 276,550 | $15M | 0.4% | 2026-Q2 |
| MARSHALL WACE, LLP added | 267,592 | $14M | 0.4% | 2026-Q2 |
| HSG Holding Ltd | 266,062 | $14M | 0.4% | 2026-Q2 |
| SEB Asset Management AB | 245,043 | $13M | 0.4% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC trimmed | 242,790 | $13M | 0.4% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC added | 230,514 | $12M | 0.3% | 2026-Q2 |
| NATIONAL BANK OF CANADA /FI/ trimmed | 215,800 | $12M | 0.3% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP added | 204,156 | $11M | 0.3% | 2026-Q2 |
| Eversept Partners, LP added | 196,302 | $11M | 0.3% | 2026-Q2 |
| Schonfeld Strategic Advisors LLC added | 190,685 | $10M | 0.3% | 2026-Q2 |
| Woodline Partners LP trimmed | 153,808 | $8M | 0.2% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. added | 153,119 | $8M | 0.2% | 2026-Q2 |
| ArrowMark Colorado Holdings LLC trimmed | 150,579 | $8M | 0.2% | 2026-Q2 |
| Susquehanna Portfolio Strategies, LLC added | 148,948 | $8M | 0.2% | 2026-Q2 |
| CenterBook Partners LP added | 148,030 | $8M | 0.2% | 2026-Q2 |
| Rhenman & Partners Asset Management AB added | 145,100 | $8M | 0.2% | 2026-Q2 |
| B Group, Inc. added | 140,000 | $8M | 0.2% | 2026-Q2 |
| HighVista Strategies LLC added | 130,784 | $7M | 0.2% | 2026-Q2 |
| Universal- Beteiligungs- und Servicegesellschaft mbH added | 125,689 | $7M | 0.2% | 2026-Q2 |
| Squarepoint Ops LLC added | 125,575 | $7M | 0.2% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 122,344 | $7M | 0.2% | 2026-Q2 |
| D. E. Shaw & Co., Inc. trimmed | 115,300 | $6M | 0.2% | 2026-Q2 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 112,300 | $6M | 0.2% | 2026-Q2 |
| Soleus Capital Management, L.P. added | 107,000 | $6M | 0.2% | 2026-Q2 |
| Avidity Partners Management LP added | 98,000 | $5M | 0.1% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 97,183 | $5M | 0.1% | 2026-Q2 |
| Qube Research & Technologies Ltd added | 93,403 | $5M | 0.1% | 2026-Q2 |
| PEREGRINE CAPITAL MANAGEMENT LLC trimmed | 92,229 | $5M | 0.1% | 2026-Q2 |
| PFM Health Sciences, LP trimmed | 91,550 | $5M | 0.1% | 2026-Q2 |
| PLATINUM INVESTMENT MANAGEMENT LTD added | 90,363 | $5M | 0.1% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 89,568 | $5M | 0.1% | 2026-Q2 |
| ExodusPoint Capital Management, LP new | 78,266 | $4M | 0.1% | 2026-Q2 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 75,000 | $4M | 0.1% | 2026-Q2 |
| Boxer Capital Management, LLC | 75,000 | $4M | 0.1% | 2026-Q2 |
| Cormorant Asset Management, LP trimmed | 75,000 | $4M | 0.1% | 2026-Q2 |
| ALPS ADVISORS INC added | 71,833 | $4M | 0.1% | 2026-Q2 |
| TD Asset Management Inc trimmed | 68,962 | $4M | 0.1% | 2026-Q2 |
| Brevan Howard Capital Management LP added | 60,336 | $3M | 0.1% | 2026-Q2 |
| Burkehill Global Management, LP | 60,000 | $3M | 0.1% | 2026-Q2 |
| RAYMOND JAMES FINANCIAL INC added | 59,357 | $3M | 0.1% | 2026-Q2 |
| TUDOR INVESTMENT CORP ET AL trimmed | 53,656 | $3M | 0.1% | 2026-Q2 |
| ANTIPODES PARTNERS Ltd added | 51,262 | $3M | 0.1% | 2026-Q2 |
| SEVEN GRAND MANAGERS, LLC | 50,000 | $3M | 0.1% | 2026-Q2 |
| Buckland Partners Management Co LLC | 50,000 | $3M | 0.1% | 2026-Q2 |
| DAFNA Capital Management LLC | 46,500 | $2M | 0.1% | 2026-Q2 |
| Mariner, LLC added | 46,285 | $2M | 0.1% | 2026-Q2 |
| OSAIC HOLDINGS, INC. added | 44,786 | $2M | 0.1% | 2026-Q2 |
| STATE STREET CORP trimmed | 44,629 | $2M | 0.1% | 2026-Q2 |
| VOYA INVESTMENT MANAGEMENT LLC | 44,410 | $2M | 0.1% | 2026-Q2 |
| BANQUE PICTET & CIE SA trimmed | 43,332 | $2M | 0.1% | 2026-Q2 |
| Jump Financial, LLC trimmed | 42,658 | $2M | 0.1% | 2026-Q2 |
| BANK OF MONTREAL /CAN/ added | 42,570 | $2M | 0.1% | 2026-Q2 |
| Cinctive Capital Management LP added | 40,877 | $2M | 0.1% | 2026-Q2 |
| Jefferies Financial Group Inc. trimmed | 40,625 | $2M | 0.1% | 2026-Q2 |
| Jones Hill Capital LP trimmed | 40,567 | $2M | 0.1% | 2026-Q2 |
| STEMPOINT CAPITAL LP trimmed | 38,178 | $2M | 0.1% | 2026-Q2 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed | 38,108 | $2M | 0.1% | 2026-Q2 |
| CAPITAL FUND MANAGEMENT S.A. added | 37,281 | $2M | 0.1% | 2026-Q2 |
| PSquared Asset Management AG added | 37,200 | $2M | 0.1% | 2026-Q2 |
| FLAX POND CAPITAL, LLC added | 37,000 | $2M | 0.0% | 2026-Q2 |
| TrueMark Investments, LLC trimmed | 33,600 | $2M | 0.1% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT CO LTD | 32,790 | $2M | 0.0% | 2026-Q2 |
| DCF Advisers, LLC added | 32,100 | $2M | 0.0% | 2026-Q2 |
| EXCHANGE TRADED CONCEPTS, LLC added | 30,773 | $2M | 0.0% | 2026-Q2 |
| Private Capital Advisors, Inc. trimmed | 29,760 | $2M | 0.0% | 2026-Q2 |
| SPHERA FUNDS MANAGEMENT LTD. trimmed | 28,600 | $2M | 0.0% | 2026-Q2 |
| Verition Fund Management LLC added | 28,519 | $2M | 0.0% | 2026-Q2 |
| Y-Intercept (Hong Kong) Ltd added | 27,573 | $1M | 0.0% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.