Who owns Fulcrum Therapeutics, Inc. (FULC)
Which tracked institutional funds hold FULC, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See FULC company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
23 tracked funds added or opened FULC while 63 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
FULC’s largest tracked holder by dollar value, SUVRETTA CAPITAL MANAGEMENT, LLC, sizes it at 1.4% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 1.4pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in FULC divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 168 tracked filers holding FULC, 109 increased or opened the position and 79 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in FULC between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 10
- VANGUARD CAPITAL MANAGEMENT LLC$21M
- Jones Hill Capital LP$14M
- Alyeska Investment Group, L.P.$10M
- Assenagon Asset Management S.A.$9M
- VANGUARD PORTFOLIO MANAGEMENT LLC$5M
- VANGUARD FIDUCIARY TRUST CO$3M
Full exits 21
- VANGUARD GROUP INC$36M
- GREAT POINT PARTNERS LLC$9M
- Sio Capital Management, LLC$4M
- Driehaus Capital Management LLC$3M
- Catalio Capital Management, LP$2M
- Nicholas Investment Partners, LP$2M
Largest adds
- AQR CAPITAL MANAGEMENT LLC$4M
- Qube Research & Technologies Ltd$3M
- Aberdeen Group plc$3M
- BALYASNY ASSET MANAGEMENT L.P.$3M
- MILLENNIUM MANAGEMENT LLC$2M
- Jump Financial, LLC$2M
Largest trims
- Nantahala Capital Management, LLC$25M
- SUVRETTA CAPITAL MANAGEMENT, LLC$24M
- RA CAPITAL MANAGEMENT, L.P.$22M
- TCG Crossover Management, LLC$19M
- ADAGE CAPITAL PARTNERS GP, L.L.C.$16M
- ADAR1 Capital Management, LLC$13M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| SUVRETTA CAPITAL MANAGEMENT, LLC | 6,561,111 | $50M | 8.2% | 2026-Q1 |
| RA CAPITAL MANAGEMENT, L.P. | 6,053,960 | $46M | 7.5% | 2026-Q1 |
| BlackRock, Inc. added | 5,390,593 | $41M | 6.7% | 2026-Q1 |
| TCG Crossover Management, LLC | 5,250,000 | $40M | 6.5% | 2026-Q1 |
| BRAIDWELL LP added | 3,134,922 | $24M | 3.9% | 2026-Q1 |
| Nantahala Capital Management, LLC trimmed | 3,050,040 | $23M | 3.8% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 2,692,948 | $21M | 3.4% | 2026-Q1 |
| Siren, L.L.C. added | 2,350,000 | $18M | 2.9% | 2026-Q1 |
| First Turn Management, LLC added | 2,256,109 | $17M | 2.8% | 2026-Q1 |
| Aberdeen Group plc added | 2,211,953 | $17M | 2.8% | 2026-Q1 |
| Point72 Asset Management, L.P. trimmed | 2,074,855 | $16M | 2.6% | 2026-Q1 |
| GSK plc | 1,785,714 | $14M | 2.2% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. added | 1,779,946 | $14M | 2.2% | 2026-Q1 |
| Jones Hill Capital LP new | 1,771,926 | $14M | 2.2% | 2026-Q1 |
| D. E. Shaw & Co., Inc. trimmed | 1,623,281 | $12M | 2.0% | 2026-Q1 |
| STATE STREET CORP added | 1,549,851 | $12M | 1.9% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,486,542 | $11M | 1.8% | 2026-Q1 |
| Alyeska Investment Group, L.P. added | 1,328,449 | $10M | 1.7% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 1,292,486 | $10M | 1.6% | 2026-Q1 |
| Assenagon Asset Management S.A. added | 1,193,873 | $9M | 1.5% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 1,130,281 | $9M | 1.4% | 2026-Q1 |
| Vestal Point Capital, LP added | 1,100,000 | $8M | 1.4% | 2026-Q1 |
| Ikarian Capital, LLC trimmed | 1,049,161 | $8M | 1.3% | 2026-Q1 |
| Qube Research & Technologies Ltd added | 974,739 | $7M | 1.2% | 2026-Q1 |
| Connor, Clark & Lunn Investment Management Ltd. added | 736,684 | $6M | 0.9% | 2026-Q1 |
| ACADIAN ASSET MANAGEMENT LLC trimmed | 727,315 | $6M | 0.9% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 599,379 | $5M | 0.7% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 571,909 | $4M | 0.7% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC added | 540,443 | $4M | 0.7% | 2026-Q1 |
| NORTHERN TRUST CORP trimmed | 472,985 | $4M | 0.6% | 2026-Q1 |
| Trexquant Investment LP added | 453,529 | $3M | 0.6% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 426,869 | $3M | 0.5% | 2026-Q1 |
| SILVERARC CAPITAL MANAGEMENT, LLC added | 419,949 | $3M | 0.5% | 2026-Q1 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 400,000 | $3M | 0.5% | 2026-Q1 |
| Jump Financial, LLC added | 369,805 | $3M | 0.5% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 356,471 | $3M | 0.4% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 329,884 | $3M | 0.4% | 2026-Q1 |
| UBS Group AG added | 315,185 | $2M | 0.4% | 2026-Q1 |
| JANE STREET GROUP, LLC trimmed | 310,417 | $2M | 0.4% | 2026-Q1 |
| BOOTHBAY FUND MANAGEMENT, LLC trimmed | 303,988 | $2M | 0.4% | 2026-Q1 |
| BESSEMER GROUP INC | 286,988 | $2M | 0.4% | 2026-Q1 |
| PANAGORA ASSET MANAGEMENT INC added | 243,565 | $2M | 0.3% | 2026-Q1 |
| DAFNA Capital Management LLC new | 205,000 | $2M | 0.3% | 2026-Q1 |
| Squarepoint Ops LLC added | 175,944 | $1M | 0.2% | 2026-Q1 |
| MORGAN STANLEY added | 173,337 | $1M | 0.2% | 2026-Q1 |
| AMERICAN CENTURY COMPANIES INC trimmed | 156,242 | $1M | 0.2% | 2026-Q1 |
| STATE OF WISCONSIN INVESTMENT BOARD added | 154,435 | $1M | 0.2% | 2026-Q1 |
| Y-Intercept (Hong Kong) Ltd added | 153,344 | $1M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp added | 149,942 | $1M | 0.2% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP added | 139,000 | $1M | 0.2% | 2026-Q1 |
| GSA CAPITAL PARTNERS LLP added | 136,664 | $1M | 0.2% | 2026-Q1 |
| Fiduciary Trust Co | 136,555 | $1M | 0.2% | 2026-Q1 |
| ADAR1 Capital Management, LLC trimmed | 130,560 | $1M | 0.2% | 2026-Q1 |
| Nuveen, LLC added | 129,618 | $994K | 0.2% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ trimmed | 126,559 | $971K | 0.2% | 2026-Q1 |
| Engineers Gate Manager LP added | 126,109 | $967K | 0.2% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 118,600 | $910K | 0.1% | 2026-Q1 |
| Simplify Asset Management Inc. trimmed | 115,994 | $890K | 0.1% | 2026-Q1 |
| Invesco Ltd. trimmed | 111,125 | $852K | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 101,336 | $777K | 0.1% | 2026-Q1 |
| BARCLAYS PLC trimmed | 88,458 | $678K | 0.1% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 80,169 | $615K | 0.1% | 2026-Q1 |
| Russell Investments Group, Ltd. added | 79,157 | $607K | 0.1% | 2026-Q1 |
| XTX Topco Ltd added | 71,603 | $549K | 0.1% | 2026-Q1 |
| RBF Capital, LLC trimmed | 70,000 | $537K | 0.1% | 2026-Q1 |
| Atom Investors LP added | 69,155 | $530K | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS added | 66,175 | $508K | 0.1% | 2026-Q1 |
| Creative Planning added | 64,089 | $492K | 0.1% | 2026-Q1 |
| FMR LLC added | 61,041 | $468K | 0.1% | 2026-Q1 |
| VANGUARD GROUP INC added | 3,214,900 | $36M | 5.9% | 2025-Q4 stale |
| GREAT POINT PARTNERS LLC new | 800,000 | $9M | 1.5% | 2025-Q4 stale |
| Sio Capital Management, LLC added | 382,000 | $4M | 0.7% | 2025-Q4 stale |
| Driehaus Capital Management LLC trimmed | 243,388 | $3M | 0.4% | 2025-Q4 stale |
| Catalio Capital Management, LP added | 201,301 | $2M | 0.4% | 2025-Q4 stale |
| Nicholas Investment Partners, LP new | 182,961 | $2M | 0.3% | 2025-Q4 stale |
| SummitTX Capital, L.P. new | 138,143 | $2M | 0.3% | 2025-Q4 stale |
| J. Goldman & Co LP added | 135,000 | $1M | 0.2% | 2025-Q3 stale |
| Walleye Capital LLC added | 108,434 | $1M | 0.2% | 2025-Q4 stale |
| MARSHALL WACE, LLP trimmed | 102,921 | $1M | 0.2% | 2025-Q4 stale |
| HRT FINANCIAL LP added | 124,924 | $1M | 0.2% | 2025-Q3 stale |
| AMERIPRISE FINANCIAL INC trimmed | 100,675 | $1M | 0.2% | 2025-Q4 stale |
| Maven Securities LTD added | 100,000 | $1M | 0.2% | 2025-Q4 stale |
| PRINCIPAL FINANCIAL GROUP INC added | 97,688 | $1M | 0.2% | 2025-Q4 stale |
| Exome Asset Management LLC trimmed | 92,055 | $1M | 0.2% | 2025-Q4 stale |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 111,582 | $1M | 0.2% | 2025-Q3 stale |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC trimmed | 95,400 | $878K | 0.1% | 2025-Q3 stale |
| Verition Fund Management LLC added | 74,691 | $845K | 0.1% | 2025-Q4 stale |
| SUPERSTRING CAPITAL MANAGEMENT LP new | 72,060 | $815K | 0.1% | 2025-Q4 stale |
| Legato Capital Management LLC new | 66,347 | $750K | 0.1% | 2025-Q4 stale |
| Integrated Quantitative Investments LLC added | 62,522 | $707K | 0.1% | 2025-Q4 stale |
| Informed Momentum Co LLC added | 61,620 | $697K | 0.1% | 2025-Q4 stale |
| Shay Capital LLC trimmed | 224,305 | $646K | 0.1% | 2025-Q1 stale |
| JACOBS LEVY EQUITY MANAGEMENT, INC trimmed | 70,015 | $644K | 0.1% | 2025-Q3 stale |
| DekaBank Deutsche Girozentrale | 60,000 | $617K | 0.1% | 2025-Q4 stale |
| SUMMIT WEALTH GROUP LLC / CO new | 533 | $616K | 0.1% | 2025-Q3 stale |
| Brooklyn Investment Group added | 62,984 | $579K | 0.1% | 2025-Q3 stale |
| SEVEN GRAND MANAGERS, LLC new | 50,000 | $566K | 0.1% | 2025-Q4 stale |
| KVP Capital Advisors, LP new | 50,000 | $566K | 0.1% | 2025-Q4 stale |
| ACUTA CAPITAL PARTNERS, LLC trimmed | 57,141 | $526K | 0.1% | 2025-Q3 stale |
| Jain Global LLC added | 41,260 | $467K | 0.1% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.