Who owns EWTX (EWTX)
Which tracked institutional funds hold EWTX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See EWTX company fundamentals →
Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
91 tracked funds added or opened EWTX while 32 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
EWTX’s largest tracked holder by dollar value, ORBIMED ADVISORS LLC, sizes it at 11.1% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 11.0pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in EWTX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 216 tracked filers holding EWTX, 110 increased or opened the position and 95 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in EWTX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 18
- VANGUARD CAPITAL MANAGEMENT LLC$119M
- VANGUARD PORTFOLIO MANAGEMENT LLC$18M
- VANGUARD FIDUCIARY TRUST CO$16M
- PEREGRINE CAPITAL MANAGEMENT LLC$7M
- SEB Asset Management AB$7M
- Freestone Grove Partners LP$5M
Full exits 11
- VANGUARD GROUP INC$106M
- DEERFIELD MANAGEMENT COMPANY, L.P.$19M
- Eversept Partners, LP$8M
- Balyasny Asset Management L.P.$4M
- Exome Asset Management LLC$2M
- Jump Financial, LLC$2M
Largest adds
- ORBIMED ADVISORS LLC$104M
- JANUS HENDERSON GROUP PLC$73M
- RA CAPITAL MANAGEMENT, L.P.$70M
- Paradigm Biocapital Advisors LP$70M
- BAKER BROS. ADVISORS LP$44M
- BlackRock, Inc.$39M
Largest trims
- BRAIDWELL LP$55M
- NORGES BANK$18M
- UBS Group AG$11M
- EVENTIDE ASSET MANAGEMENT, LLC$9M
- First Light Asset Management, LLC$7M
- D. E. Shaw & Co., Inc.$6M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 15,518,492 | $489M | 12.4% | 2026-Q1 |
| RA CAPITAL MANAGEMENT, L.P. | 10,428,437 | $328M | 8.4% | 2026-Q1 |
| Paradigm Biocapital Advisors LP added | 7,365,038 | $232M | 5.9% | 2026-Q1 |
| BAKER BROS. ADVISORS LP | 6,575,940 | $207M | 5.3% | 2026-Q1 |
| BlackRock, Inc. trimmed | 6,472,991 | $204M | 5.2% | 2026-Q1 |
| JANUS HENDERSON GROUP PLC added | 5,915,556 | $186M | 4.7% | 2026-Q1 |
| NOVO HOLDINGS A/S | 5,350,000 | $169M | 4.3% | 2026-Q1 |
| Driehaus Capital Management LLC added | 4,477,942 | $141M | 3.6% | 2026-Q1 |
| Siren, L.L.C. trimmed | 4,430,263 | $140M | 3.6% | 2026-Q1 |
| PERCEPTIVE ADVISORS LLC trimmed | 4,423,974 | $139M | 3.5% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 3,788,161 | $119M | 3.0% | 2026-Q1 |
| Cormorant Asset Management, LP trimmed | 3,260,000 | $103M | 2.6% | 2026-Q1 |
| BRAIDWELL LP trimmed | 2,347,583 | $74M | 1.9% | 2026-Q1 |
| MORGAN STANLEY trimmed | 2,246,028 | $71M | 1.8% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,789,819 | $56M | 1.4% | 2026-Q1 |
| STATE STREET CORP trimmed | 1,716,823 | $54M | 1.4% | 2026-Q1 |
| MPM BIOIMPACT LLC added | 1,660,696 | $52M | 1.3% | 2026-Q1 |
| Integral Health Asset Management, LLC added | 1,600,000 | $50M | 1.3% | 2026-Q1 |
| Bellevue Group AG | 1,528,518 | $48M | 1.2% | 2026-Q1 |
| Soleus Capital Management, L.P. added | 1,449,915 | $46M | 1.2% | 2026-Q1 |
| ALLIANCEBERNSTEIN L.P. added | 1,722,169 | $43M | 1.1% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ trimmed | 1,327,360 | $42M | 1.1% | 2026-Q1 |
| UBS Group AG trimmed | 1,311,125 | $41M | 1.1% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 1,219,717 | $38M | 1.0% | 2026-Q1 |
| AMERICAN CENTURY COMPANIES INC trimmed | 1,147,176 | $36M | 0.9% | 2026-Q1 |
| FMR LLC added | 1,016,793 | $32M | 0.8% | 2026-Q1 |
| First Light Asset Management, LLC trimmed | 1,001,846 | $32M | 0.8% | 2026-Q1 |
| Aberdeen Group plc added | 826,059 | $26M | 0.7% | 2026-Q1 |
| Qube Research & Technologies Ltd added | 825,910 | $26M | 0.7% | 2026-Q1 |
| VICTORY CAPITAL MANAGEMENT INC added | 789,043 | $25M | 0.6% | 2026-Q1 |
| Artisan Partners Limited Partnership trimmed | 659,067 | $21M | 0.5% | 2026-Q1 |
| MARSHALL WACE, LLP trimmed | 648,393 | $20M | 0.5% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC trimmed | 629,820 | $20M | 0.5% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed | 596,310 | $19M | 0.5% | 2026-Q1 |
| NORTHERN TRUST CORP added | 576,556 | $18M | 0.5% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 557,260 | $18M | 0.4% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 521,726 | $16M | 0.4% | 2026-Q1 |
| Opaleye Management Inc. | 500,000 | $16M | 0.4% | 2026-Q1 |
| Candriam S.C.A. trimmed | 447,416 | $14M | 0.4% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 429,032 | $14M | 0.3% | 2026-Q1 |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND trimmed | 404,200 | $13M | 0.3% | 2026-Q1 |
| Sofinnova Investments, Inc. trimmed | 386,498 | $12M | 0.3% | 2026-Q1 |
| Squadron Capital Management LLC | 350,000 | $11M | 0.3% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 342,867 | $11M | 0.3% | 2026-Q1 |
| Nuveen, LLC added | 335,783 | $11M | 0.3% | 2026-Q1 |
| Parkman Healthcare Partners LLC trimmed | 322,828 | $10M | 0.3% | 2026-Q1 |
| STEMPOINT CAPITAL LP trimmed | 290,864 | $9M | 0.2% | 2026-Q1 |
| Universal- Beteiligungs- und Servicegesellschaft mbH added | 283,312 | $9M | 0.2% | 2026-Q1 |
| Sio Capital Management, LLC added | 268,986 | $8M | 0.2% | 2026-Q1 |
| KENNEDY CAPITAL MANAGEMENT LLC added | 264,204 | $8M | 0.2% | 2026-Q1 |
| Woodline Partners LP added | 224,290 | $7M | 0.2% | 2026-Q1 |
| DEUTSCHE BANK AG\ added | 221,868 | $7M | 0.2% | 2026-Q1 |
| PEREGRINE CAPITAL MANAGEMENT LLC new | 208,672 | $7M | 0.2% | 2026-Q1 |
| SEB Asset Management AB new | 206,512 | $7M | 0.2% | 2026-Q1 |
| Granahan Investment Management, LLC trimmed | 200,843 | $6M | 0.2% | 2026-Q1 |
| AMERIPRISE FINANCIAL INC trimmed | 200,661 | $6M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp trimmed | 192,434 | $6M | 0.2% | 2026-Q1 |
| BARCLAYS PLC trimmed | 177,244 | $6M | 0.1% | 2026-Q1 |
| NEUBERGER BERMAN GROUP LLC added | 168,678 | $5M | 0.1% | 2026-Q1 |
| Ally Bridge Group (NY) LLC trimmed | 161,000 | $5M | 0.1% | 2026-Q1 |
| EVENTIDE ASSET MANAGEMENT, LLC trimmed | 149,863 | $5M | 0.1% | 2026-Q1 |
| Freestone Grove Partners LP new | 148,426 | $5M | 0.1% | 2026-Q1 |
| JPMORGAN CHASE & CO added | 147,573 | $4M | 0.1% | 2026-Q1 |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 145,286 | $4M | 0.1% | 2026-Q1 |
| Invesco Ltd. added | 138,399 | $4M | 0.1% | 2026-Q1 |
| KVP Capital Advisors, LP | 133,000 | $4M | 0.1% | 2026-Q1 |
| Quantum Private Wealth, LLC added | 116,624 | $4M | 0.1% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 114,720 | $4M | 0.1% | 2026-Q1 |
| Moody Aldrich Partners LLC added | 114,141 | $4M | 0.1% | 2026-Q1 |
| DAFNA Capital Management LLC trimmed | 112,236 | $4M | 0.1% | 2026-Q1 |
| D. E. Shaw & Co., Inc. trimmed | 104,863 | $3M | 0.1% | 2026-Q1 |
| Swiss National Bank | 103,900 | $3M | 0.1% | 2026-Q1 |
| Schonfeld Strategic Advisors LLC added | 99,075 | $3M | 0.1% | 2026-Q1 |
| HighVista Strategies LLC trimmed | 91,931 | $3M | 0.1% | 2026-Q1 |
| ADAR1 Capital Management, LLC trimmed | 90,599 | $3M | 0.1% | 2026-Q1 |
| NEW YORK STATE COMMON RETIREMENT FUND | 88,937 | $3M | 0.1% | 2026-Q1 |
| ALPS ADVISORS INC added | 87,326 | $3M | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS trimmed | 83,540 | $3M | 0.1% | 2026-Q1 |
| DekaBank Deutsche Girozentrale | 80,000 | $3M | 0.1% | 2026-Q1 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 73,419 | $2M | 0.1% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 69,427 | $2M | 0.1% | 2026-Q1 |
| VANGUARD GROUP INC trimmed | 4,277,840 | $106M | 2.7% | 2025-Q4 stale |
| Deep Track Capital, LP added | 1,400,000 | $31M | 0.8% | 2025-Q1 stale |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 765,694 | $19M | 0.5% | 2025-Q4 stale |
| New Leaf Venture Partners, L.L.C. | 1,030,161 | $17M | 0.4% | 2025-Q3 stale |
| Polar Capital Holdings Plc added | 975,000 | $13M | 0.3% | 2025-Q2 stale |
| VIKING GLOBAL INVESTORS LP trimmed | 490,035 | $11M | 0.3% | 2025-Q1 stale |
| ADAGE CAPITAL PARTNERS GP, L.L.C. added | 390,000 | $9M | 0.2% | 2025-Q1 stale |
| Eversept Partners, LP trimmed | 337,340 | $8M | 0.2% | 2025-Q4 stale |
| READYSTATE ASSET MANAGEMENT LP added | 361,233 | $8M | 0.2% | 2025-Q1 stale |
| Foresite Capital Management VI LLC | 585,000 | $8M | 0.2% | 2025-Q2 stale |
| TANG CAPITAL MANAGEMENT LLC | 431,300 | $7M | 0.2% | 2025-Q3 stale |
| Ikarian Capital, LLC added | 280,000 | $6M | 0.2% | 2025-Q1 stale |
| AMUNDI trimmed | 308,633 | $4M | 0.1% | 2025-Q1 stale |
| Kynam Capital Management, LP | 253,979 | $4M | 0.1% | 2025-Q3 stale |
| Balyasny Asset Management L.P. added | 151,905 | $4M | 0.1% | 2025-Q4 stale |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC added | 284,551 | $4M | 0.1% | 2025-Q2 stale |
| JENNISON ASSOCIATES LLC new | 128,746 | $3M | 0.1% | 2025-Q1 stale |
| Exome Asset Management LLC trimmed | 100,046 | $2M | 0.1% | 2025-Q4 stale |
| EFG Asset Management (North America) Corp. added | 104,386 | $2M | 0.1% | 2025-Q1 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.