Who owns Denali Therapeutics (DNLI)
Which tracked institutional funds hold DNLI, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See DNLI company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on DNLI is one-sided between 2026-Q1 and 2026-Q2: 115 added or opened and 38 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
DNLI’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes DNLI more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in DNLI divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 274 tracked filers holding DNLI, 166 increased or opened the position and 113 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in DNLI between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 13
- ExodusPoint Capital Management, LP$9M
- E. Ohman J:or Asset Management AB$4M
- Odyssean, LLC$3M
- PFM Health Sciences, LP$3M
- Integral Health Asset Management, LLC$3M
- Phocas Financial Corp.$2M
Full exits 21
- T. Rowe Price Investment Management, Inc.$164M
- Vestal Point Capital, LP$34M
- STEMPOINT CAPITAL LP$8M
- BRAIDWELL LP$6M
- SCHRODER INVESTMENT MANAGEMENT GROUP$5M
- Palo Alto Investors LP$5M
Largest adds
- BlackRock, Inc.$110M
- BAILLIE GIFFORD & CO$76M
- STATE STREET CORP$61M
- NOMURA ASSET MANAGEMENT INTERNATIONAL INC.$55M
- VANGUARD PORTFOLIO MANAGEMENT LLC$49M
- Temasek Holdings (Private) Ltd$46M
Largest trims
- Lynx1 Capital Management LP$36M
- Alyeska Investment Group, L.P.$32M
- Defilade Capital Management, L.P.$16M
- Clearstead Advisors, LLC$14M
- ADAR1 Capital Management, LLC$9M
- MASTERS CAPITAL MANAGEMENT LLC$6M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| BlackRock, Inc. added | 14,026,413 | $361M | 10.3% | 2026-Q2 |
| BAILLIE GIFFORD & CO trimmed | 11,960,230 | $308M | 8.8% | 2026-Q2 |
| STATE STREET CORP added | 7,049,304 | $181M | 5.2% | 2026-Q2 |
| Temasek Holdings (Private) Ltd | 7,012,974 | $180M | 5.1% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 6,477,057 | $167M | 4.7% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 6,275,729 | $161M | 4.6% | 2026-Q2 |
| FMR LLC trimmed | 4,535,836 | $117M | 3.3% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC trimmed | 4,155,895 | $107M | 3.0% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 3,973,342 | $102M | 2.9% | 2026-Q2 |
| Holocene Advisors, LP added | 3,905,225 | $100M | 2.9% | 2026-Q2 |
| BAKER BROS. ADVISORS LP added | 3,734,336 | $96M | 2.7% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 3,161,972 | $81M | 2.3% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 3,136,149 | $81M | 2.3% | 2026-Q2 |
| UBS Group AG added | 3,120,592 | $80M | 2.3% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. added | 2,984,807 | $57M | 1.6% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP added | 2,860,604 | $74M | 2.1% | 2026-Q2 |
| NORGES BANK trimmed | 2,824,746 | $73M | 2.1% | 2026-Q2 |
| Pictet Asset Management Holding SA added | 2,791,206 | $72M | 2.0% | 2026-Q2 |
| Capital Research Global Investors added | 2,565,817 | $66M | 1.9% | 2026-Q2 |
| Fisher Asset Management, LLC trimmed | 2,414,162 | $62M | 1.8% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. added | 2,208,263 | $57M | 1.6% | 2026-Q2 |
| Casdin Capital, LLC added | 2,045,000 | $53M | 1.5% | 2026-Q2 |
| Crestline Management, L.P. trimmed | 1,910,732 | $49M | 1.4% | 2026-Q2 |
| PRINCIPAL FINANCIAL GROUP INC trimmed | 1,420,083 | $37M | 1.0% | 2026-Q2 |
| Foresite Capital Management VI LLC added | 1,396,771 | $36M | 1.0% | 2026-Q2 |
| Siren, L.L.C. | 1,396,513 | $36M | 1.0% | 2026-Q2 |
| NORTHERN TRUST CORP added | 1,389,765 | $36M | 1.0% | 2026-Q2 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. added | 1,355,514 | $35M | 1.0% | 2026-Q2 |
| Aberdeen Group plc trimmed | 1,345,481 | $35M | 1.0% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 1,244,955 | $32M | 0.9% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 1,230,957 | $32M | 0.9% | 2026-Q2 |
| Artisan Partners Limited Partnership added | 1,224,497 | $31M | 0.9% | 2026-Q2 |
| Candriam S.C.A. added | 1,189,886 | $31M | 0.9% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 1,125,748 | $29M | 0.8% | 2026-Q2 |
| ADAR1 Capital Management, LLC trimmed | 1,029,080 | $26M | 0.8% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 991,904 | $26M | 0.7% | 2026-Q2 |
| MORGAN STANLEY trimmed | 961,050 | $25M | 0.7% | 2026-Q2 |
| Bank of New York Mellon Corp added | 800,283 | $21M | 0.6% | 2026-Q2 |
| DAFNA Capital Management LLC added | 739,014 | $19M | 0.5% | 2026-Q2 |
| AMERICAN CENTURY COMPANIES INC trimmed | 712,526 | $18M | 0.5% | 2026-Q2 |
| Cercano Management LLC | 625,000 | $16M | 0.5% | 2026-Q2 |
| Nuveen, LLC added | 608,967 | $16M | 0.4% | 2026-Q2 |
| Ensign Peak Advisors, Inc added | 582,669 | $15M | 0.4% | 2026-Q2 |
| MARSHALL WACE, LLP trimmed | 549,830 | $14M | 0.4% | 2026-Q2 |
| SEGALL BRYANT & HAMILL, LLC trimmed | 519,483 | $13M | 0.4% | 2026-Q2 |
| CITIGROUP INC added | 487,278 | $13M | 0.4% | 2026-Q2 |
| Defilade Capital Management, L.P. trimmed | 391,866 | $10M | 0.3% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC added | 388,469 | $10M | 0.3% | 2026-Q2 |
| Woodline Partners LP | 364,082 | $9M | 0.3% | 2026-Q2 |
| Invesco Ltd. added | 343,898 | $9M | 0.3% | 2026-Q2 |
| ExodusPoint Capital Management, LP trimmed | 336,567 | $9M | 0.2% | 2026-Q2 |
| Marex Group Ltd added | 295,631 | $8M | 0.2% | 2026-Q2 |
| JPMORGAN CHASE & CO trimmed | 287,019 | $8M | 0.2% | 2026-Q2 |
| Swiss National Bank trimmed | 270,500 | $7M | 0.2% | 2026-Q2 |
| TD Asset Management Inc trimmed | 231,644 | $6M | 0.2% | 2026-Q2 |
| GROUPAMA ASSET MANAGMENT added | 229,939 | $6M | 0.2% | 2026-Q2 |
| Privium Fund Management B.V. trimmed | 229,857 | $6M | 0.2% | 2026-Q2 |
| XTX Topco Ltd added | 226,953 | $6M | 0.2% | 2026-Q2 |
| Alyeska Investment Group, L.P. trimmed | 219,334 | $6M | 0.2% | 2026-Q2 |
| Susquehanna Portfolio Strategies, LLC added | 211,474 | $5M | 0.2% | 2026-Q2 |
| MASTERS CAPITAL MANAGEMENT LLC trimmed | 200,000 | $5M | 0.1% | 2026-Q2 |
| Burkehill Global Management, LP | 200,000 | $5M | 0.1% | 2026-Q2 |
| SCS Capital Management LLC | 197,998 | $5M | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 194,787 | $5M | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 189,865 | $5M | 0.1% | 2026-Q2 |
| Universal- Beteiligungs- und Servicegesellschaft mbH added | 179,195 | $5M | 0.1% | 2026-Q2 |
| Rhenman & Partners Asset Management AB trimmed | 179,000 | $5M | 0.1% | 2026-Q2 |
| NEW YORK STATE COMMON RETIREMENT FUND added | 171,712 | $4M | 0.1% | 2026-Q2 |
| EDMOND DE ROTHSCHILD HOLDING S.A. trimmed | 165,080 | $4M | 0.1% | 2026-Q2 |
| ALPS ADVISORS INC added | 160,378 | $4M | 0.1% | 2026-Q2 |
| E. Ohman J:or Asset Management AB new | 160,000 | $4M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM trimmed | 152,086 | $4M | 0.1% | 2026-Q2 |
| DEUTSCHE BANK AG\ added | 149,804 | $4M | 0.1% | 2026-Q2 |
| GREAT LAKES ADVISORS, LLC trimmed | 145,045 | $4M | 0.1% | 2026-Q2 |
| VANGUARD ASSET MANAGEMENT, Ltd added | 141,153 | $4M | 0.1% | 2026-Q2 |
| Man Group plc added | 139,065 | $4M | 0.1% | 2026-Q2 |
| Hudson Bay Capital Management LP trimmed | 130,000 | $3M | 0.1% | 2026-Q2 |
| Odyssean, LLC new | 125,062 | $3M | 0.1% | 2026-Q2 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 123,258 | $3M | 0.1% | 2026-Q2 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed | 117,348 | $3M | 0.1% | 2026-Q2 |
| Zurcher Kantonalbank (Zurich Cantonalbank) added | 115,775 | $3M | 0.1% | 2026-Q2 |
| B. Metzler seel. Sohn & Co. AG | 112,300 | $3M | 0.1% | 2026-Q2 |
| Legal & General Group Plc added | 111,953 | $3M | 0.1% | 2026-Q2 |
| Integrated Wealth Concepts LLC added | 102,241 | $3M | 0.1% | 2026-Q2 |
| PFM Health Sciences, LP new | 100,966 | $3M | 0.1% | 2026-Q2 |
| Ghisallo Capital Management LLC | 100,000 | $3M | 0.1% | 2026-Q2 |
| Integral Health Asset Management, LLC new | 100,000 | $3M | 0.1% | 2026-Q2 |
| Lumbard & Kellner, LLC added | 98,282 | $3M | 0.1% | 2026-Q2 |
| Rafferty Asset Management, LLC trimmed | 96,342 | $2M | 0.1% | 2026-Q2 |
| D.A. DAVIDSON & CO. trimmed | 87,741 | $2M | 0.1% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 86,032 | $2M | 0.1% | 2026-Q2 |
| MetLife Investment Management, LLC added | 85,621 | $2M | 0.1% | 2026-Q2 |
| BARCLAYS PLC added | 84,892 | $2M | 0.1% | 2026-Q2 |
| STATE OF WISCONSIN INVESTMENT BOARD added | 84,652 | $2M | 0.1% | 2026-Q2 |
| Creative Planning added | 84,644 | $2M | 0.1% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC trimmed | 82,650 | $2M | 0.1% | 2026-Q2 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. trimmed | 78,937 | $2M | 0.1% | 2026-Q2 |
| Phocas Financial Corp. new | 71,197 | $2M | 0.1% | 2026-Q2 |
| Knights of Columbus Asset Advisors LLC added | 67,591 | $2M | 0.0% | 2026-Q2 |
| CITADEL ADVISORS LLC trimmed | 66,971 | $2M | 0.0% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.