Who owns Definium Therapeutics (DFTX)
Which tracked institutional funds hold DFTX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See DFTX company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
The tracked-fund tape on DFTX is one-sided between 2026-Q1 and 2026-Q2: 205 added or opened and 15 trimmed or exited — on balance accumulating.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
DFTX’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 0.0pp gap the other way — the median holder sizes DFTX more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in DFTX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 348 tracked filers holding DFTX, 257 increased or opened the position and 104 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in DFTX between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 65
- Jupiter Topco LLC$264M
- Capital World Investors$252M
- Capital International Investors$139M
- RA CAPITAL MANAGEMENT, L.P.$71M
- Polar Capital Holdings Plc$37M
- BAMCO INC /NY/$24M
Full exits 12
- Trails Edge Capital Partners, LP$33M
- Patient Square Capital LP$6M
- JANE STREET GROUP, LLC$5M
- Soviero Asset Management, LP$3M
- Squarepoint Ops LLC$2M
- Rosalind Advisors, Inc.$2M
Largest adds
- BlackRock, Inc.$368M
- Avoro Capital Advisors LLC$244M
- PRICE T ROWE ASSOCIATES INC /MD/$218M
- Driehaus Capital Management LLC$210M
- FMR LLC$189M
- GEODE CAPITAL MANAGEMENT, LLC$124M
Largest trims
- ArrowMark Colorado Holdings LLC$4M
- MILLENNIUM MANAGEMENT LLC$3M
- DEUTSCHE BANK AG\$1M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| BlackRock, Inc. added | 11,232,834 | $528M | 10.3% | 2026-Q2 |
| Avoro Capital Advisors LLC added | 7,188,888 | $338M | 6.6% | 2026-Q2 |
| Driehaus Capital Management LLC added | 6,845,276 | $322M | 6.3% | 2026-Q2 |
| Jupiter Topco LLC new | 5,615,645 | $264M | 5.2% | 2026-Q2 |
| Capital World Investors new | 5,367,723 | $252M | 4.9% | 2026-Q2 |
| FMR LLC added | 4,752,921 | $224M | 4.4% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 4,652,032 | $219M | 4.3% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 3,644,813 | $171M | 3.3% | 2026-Q2 |
| STATE STREET CORP added | 3,065,390 | $144M | 2.8% | 2026-Q2 |
| Capital International Investors new | 2,963,410 | $139M | 2.7% | 2026-Q2 |
| Octagon Capital Advisors LP added | 2,950,000 | $139M | 2.7% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP added | 2,949,734 | $139M | 2.7% | 2026-Q2 |
| Deep Track Capital, LP trimmed | 2,750,000 | $129M | 2.5% | 2026-Q2 |
| Commodore Capital LP | 2,000,000 | $94M | 1.8% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. added | 1,803,287 | $34M | 0.7% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 1,800,852 | $85M | 1.7% | 2026-Q2 |
| CITADEL ADVISORS LLC added | 1,688,587 | $79M | 1.5% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 1,648,426 | $78M | 1.5% | 2026-Q2 |
| RA CAPITAL MANAGEMENT, L.P. new | 1,500,000 | $71M | 1.4% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 1,486,454 | $70M | 1.4% | 2026-Q2 |
| Siren, L.L.C. added | 1,419,493 | $67M | 1.3% | 2026-Q2 |
| MARSHALL WACE, LLP added | 1,298,946 | $61M | 1.2% | 2026-Q2 |
| NORTHERN TRUST CORP added | 1,169,238 | $55M | 1.1% | 2026-Q2 |
| AMERIPRISE FINANCIAL INC added | 1,148,363 | $54M | 1.1% | 2026-Q2 |
| Nuveen, LLC added | 1,105,314 | $52M | 1.0% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 1,083,576 | $51M | 1.0% | 2026-Q2 |
| Woodline Partners LP added | 1,003,641 | $47M | 0.9% | 2026-Q2 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 1,000,000 | $47M | 0.9% | 2026-Q2 |
| Boxer Capital Management, LLC added | 998,500 | $47M | 0.9% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP trimmed | 921,818 | $43M | 0.8% | 2026-Q2 |
| BALYASNY ASSET MANAGEMENT L.P. trimmed | 897,658 | $42M | 0.8% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 827,693 | $39M | 0.8% | 2026-Q2 |
| Holocene Advisors, LP trimmed | 796,574 | $37M | 0.7% | 2026-Q2 |
| AWM Investment Company, Inc. trimmed | 784,800 | $37M | 0.7% | 2026-Q2 |
| Bank of New York Mellon Corp added | 777,271 | $37M | 0.7% | 2026-Q2 |
| Polar Capital Holdings Plc new | 777,253 | $37M | 0.7% | 2026-Q2 |
| EVENTIDE ASSET MANAGEMENT, LLC added | 710,000 | $33M | 0.7% | 2026-Q2 |
| NEUBERGER BERMAN GROUP LLC added | 687,539 | $32M | 0.6% | 2026-Q2 |
| Qube Research & Technologies Ltd added | 682,901 | $32M | 0.6% | 2026-Q2 |
| Candriam S.C.A. trimmed | 614,425 | $29M | 0.6% | 2026-Q2 |
| ArrowMark Colorado Holdings LLC trimmed | 564,069 | $27M | 0.5% | 2026-Q2 |
| Catalio Capital Management, LP trimmed | 562,672 | $26M | 0.5% | 2026-Q2 |
| Blackstone Inc. added | 561,612 | $26M | 0.5% | 2026-Q2 |
| Integral Health Asset Management, LLC added | 550,000 | $26M | 0.5% | 2026-Q2 |
| BAMCO INC /NY/ new | 520,108 | $24M | 0.5% | 2026-Q2 |
| UBS Group AG added | 499,467 | $23M | 0.5% | 2026-Q2 |
| FRANKLIN RESOURCES INC new | 486,219 | $23M | 0.4% | 2026-Q2 |
| Point72 Asset Management, L.P. added | 483,980 | $23M | 0.4% | 2026-Q2 |
| Ensign Peak Advisors, Inc trimmed | 466,106 | $22M | 0.4% | 2026-Q2 |
| MORGAN STANLEY added | 454,912 | $21M | 0.4% | 2026-Q2 |
| GREAT POINT PARTNERS LLC new | 425,000 | $20M | 0.4% | 2026-Q2 |
| Cormorant Asset Management, LP new | 400,000 | $19M | 0.4% | 2026-Q2 |
| RTW INVESTMENTS, LP added | 400,000 | $19M | 0.4% | 2026-Q2 |
| SILVERARC CAPITAL MANAGEMENT, LLC new | 400,000 | $19M | 0.4% | 2026-Q2 |
| ASSETMARK, INC new | 396,542 | $19M | 0.4% | 2026-Q2 |
| ORBIMED ADVISORS LLC trimmed | 365,400 | $17M | 0.3% | 2026-Q2 |
| Duquesne Family Office LLC new | 356,600 | $17M | 0.3% | 2026-Q2 |
| D. E. Shaw & Co., Inc. added | 315,410 | $15M | 0.3% | 2026-Q2 |
| Tetragon Partners GP Ltd added | 286,990 | $14M | 0.3% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC trimmed | 266,076 | $13M | 0.2% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 265,955 | $12M | 0.2% | 2026-Q2 |
| Sofinnova Investments, Inc. trimmed | 255,903 | $12M | 0.2% | 2026-Q2 |
| PFM Health Sciences, LP added | 249,020 | $12M | 0.2% | 2026-Q2 |
| HighVista Strategies LLC added | 242,884 | $11M | 0.2% | 2026-Q2 |
| Trexquant Investment LP new | 233,199 | $11M | 0.2% | 2026-Q2 |
| SEVEN GRAND MANAGERS, LLC | 225,000 | $11M | 0.2% | 2026-Q2 |
| Swiss National Bank added | 221,200 | $10M | 0.2% | 2026-Q2 |
| Eversept Partners, LP added | 217,185 | $10M | 0.2% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 211,183 | $10M | 0.2% | 2026-Q2 |
| TD Asset Management Inc new | 209,460 | $10M | 0.2% | 2026-Q2 |
| ROYCE & ASSOCIATES LP trimmed | 208,551 | $10M | 0.2% | 2026-Q2 |
| SEB Asset Management AB new | 208,254 | $10M | 0.2% | 2026-Q2 |
| SUPERSTRING CAPITAL MANAGEMENT LP trimmed | 188,282 | $9M | 0.2% | 2026-Q2 |
| EMERALD ADVISERS, LLC new | 178,751 | $8M | 0.2% | 2026-Q2 |
| Aberdeen Group plc new | 175,000 | $8M | 0.2% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ added | 164,575 | $8M | 0.2% | 2026-Q2 |
| Tri Locum Partners LP trimmed | 162,996 | $8M | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 158,096 | $7M | 0.1% | 2026-Q2 |
| Brevan Howard Capital Management LP trimmed | 156,812 | $7M | 0.1% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 153,477 | $7M | 0.1% | 2026-Q2 |
| LMR Partners LLP new | 150,200 | $7M | 0.1% | 2026-Q2 |
| Seven Fleet Capital Management LP added | 148,647 | $7M | 0.1% | 2026-Q2 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE added | 146,368 | $7M | 0.1% | 2026-Q2 |
| Rock Springs Capital Management LP new | 143,187 | $7M | 0.1% | 2026-Q2 |
| DEUTSCHE BANK AG\ trimmed | 142,947 | $7M | 0.1% | 2026-Q2 |
| SummitTX Capital, L.P. new | 142,489 | $7M | 0.1% | 2026-Q2 |
| STEMPOINT CAPITAL LP trimmed | 137,124 | $6M | 0.1% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC added | 134,152 | $6M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM new | 128,346 | $6M | 0.1% | 2026-Q2 |
| BIT Capital GmbH trimmed | 128,131 | $6M | 0.1% | 2026-Q2 |
| FRED ALGER MANAGEMENT, LLC added | 125,256 | $6M | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 122,033 | $6M | 0.1% | 2026-Q2 |
| Atika Capital Management LLC new | 122,000 | $6M | 0.1% | 2026-Q2 |
| AdvisorShares Investments LLC added | 121,381 | $6M | 0.1% | 2026-Q2 |
| EMERALD MUTUAL FUND ADVISERS TRUST new | 121,249 | $6M | 0.1% | 2026-Q2 |
| Informed Momentum Co LLC new | 120,928 | $6M | 0.1% | 2026-Q2 |
| Schonfeld Strategic Advisors LLC added | 119,610 | $6M | 0.1% | 2026-Q2 |
| HSBC HOLDINGS PLC new | 117,482 | $6M | 0.1% | 2026-Q2 |
| ALPS ADVISORS INC new | 110,388 | $5M | 0.1% | 2026-Q2 |
| Data Collective IV GP, LLC | 100,350 | $5M | 0.1% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.