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Institutional Ownership · SEC Form 13F

Who owns CYRX (CYRX)


Which tracked institutional funds hold CYRX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See CYRX company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

166
Institutional holders
46,129,093
Shares held (tracked funds)
92.5%
Of shares outstanding

How the tape is positioned

20 tracked funds added or opened CYRX while 46 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

CYRX’s largest tracked holder by dollar value, CADIAN CAPITAL MANAGEMENT, LP, sizes it at 4.8% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 4.8pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in CYRX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 166 tracked filers holding CYRX, 82 increased or opened the position and 73 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in CYRX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 8

  • VANGUARD CAPITAL MANAGEMENT LLC$18M
  • MIROVA$10M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$4M
  • VANGUARD FIDUCIARY TRUST CO$3M
  • NORGES BANK$2M
  • Kopion Asset Management, LLC$2M

Full exits 5

  • VANGUARD GROUP INC$25M
  • Brandywine Global Investment Management, LLC$1M
  • JACOBS LEVY EQUITY MANAGEMENT, INC$917K
  • AlphaQuest LLC$677K
  • Caption Management, LLC$576K

Largest adds

  • INTRINSIC EDGE CAPITAL MANAGEMENT LLC$4M
  • First Eagle Investment Management, LLC$3M
  • Granahan Investment Management, LLC$2M
  • Penbrook Management LLC$1M
  • FRANKLIN RESOURCES INC$950K
  • RENAISSANCE TECHNOLOGIES LLC$878K

Largest trims

  • CADIAN CAPITAL MANAGEMENT, LP$8M
  • MILLENNIUM MANAGEMENT LLC$7M
  • MORGAN STANLEY$6M
  • UBS Group AG$6M
  • BlackRock, Inc.$5M
  • BROWN CAPITAL MANAGEMENT LLC$4M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
CADIAN CAPITAL MANAGEMENT, LP trimmed4,776,343$40M9.0%2026-Q1
MORGAN STANLEY trimmed4,576,730$38M8.6%2026-Q1
BlackRock, Inc. trimmed3,980,898$33M7.5%2026-Q1
MILLENNIUM MANAGEMENT LLC trimmed2,970,464$25M5.6%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new2,118,856$18M4.0%2026-Q1
FRED ALGER MANAGEMENT, LLC trimmed1,699,379$14M3.2%2026-Q1
Assenagon Asset Management S.A. added1,495,683$12M2.8%2026-Q1
MAK CAPITAL ONE LLC added1,423,265$12M2.7%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added1,248,135$10M2.4%2026-Q1
MIROVA new1,158,277$10M2.2%2026-Q1
DEUTSCHE BANK AG\ added1,000,676$8M1.9%2026-Q1
STATE STREET CORP added983,878$8M1.9%2026-Q1
UBS Group AG trimmed932,782$8M1.8%2026-Q1
DIMENSIONAL FUND ADVISORS LP trimmed923,707$8M1.7%2026-Q1
SILVERCREST ASSET MANAGEMENT GROUP LLC added901,010$7M1.7%2026-Q1
BROWN CAPITAL MANAGEMENT LLC trimmed780,564$6M1.5%2026-Q1
BNP PARIBAS ASSET MANAGEMENT Holding S.A. added778,361$6M1.5%2026-Q1
First Eagle Investment Management, LLC added744,849$6M1.4%2026-Q1
INTRINSIC EDGE CAPITAL MANAGEMENT LLC added630,000$5M1.2%2026-Q1
ACADIAN ASSET MANAGEMENT LLC trimmed628,062$5M1.2%2026-Q1
Meros Investment Management, LP trimmed609,073$5M1.1%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new513,634$4M1.0%2026-Q1
Empire Financial Management Company, LLC added502,575$4M0.9%2026-Q1
NORTHERN TRUST CORP added467,628$4M0.9%2026-Q1
Blackstone Inc.453,396$4M0.9%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed417,564$3M0.8%2026-Q1
RENAISSANCE TECHNOLOGIES LLC added368,110$3M0.7%2026-Q1
NEEDHAM INVESTMENT MANAGEMENT LLC added360,000$3M0.7%2026-Q1
TOCQUEVILLE ASSET MANAGEMENT L.P.355,000$3M0.7%2026-Q1
TUDOR INVESTMENT CORP ET AL added351,200$3M0.7%2026-Q1
VANGUARD FIDUCIARY TRUST CO new336,420$3M0.6%2026-Q1
Archon Capital Management LLC325,268$3M0.6%2026-Q1
AQR CAPITAL MANAGEMENT LLC added323,142$3M0.6%2026-Q1
Bullseye Asset Management LLC315,069$3M0.6%2026-Q1
JANE STREET GROUP, LLC added292,654$2M0.6%2026-Q1
NORGES BANK348,500$2M0.5%2026-Q1
Granahan Investment Management, LLC added231,138$2M0.4%2026-Q1
READYSTATE ASSET MANAGEMENT LP trimmed228,822$2M0.4%2026-Q1
PHILADELPHIA TRUST CO trimmed228,173$2M0.4%2026-Q1
Trexquant Investment LP added223,503$2M0.4%2026-Q1
Kopion Asset Management, LLC new209,162$2M0.4%2026-Q1
FEDERATED HERMES, INC.208,937$2M0.4%2026-Q1
PERKINS CAPITAL MANAGEMENT INC trimmed203,247$2M0.4%2026-Q1
Bank of New York Mellon Corp trimmed200,474$2M0.4%2026-Q1
GOLDMAN SACHS GROUP INC trimmed198,834$2M0.4%2026-Q1
Penbrook Management LLC added185,775$2M0.4%2026-Q1
STIFEL FINANCIAL CORP added183,280$2M0.3%2026-Q1
CITADEL ADVISORS LLC trimmed183,178$2M0.3%2026-Q1
FRANKLIN RESOURCES INC added181,843$2M0.3%2026-Q1
JPMORGAN CHASE & CO trimmed186,945$1M0.3%2026-Q1
Conestoga Capital Advisors, LLC159,864$1M0.3%2026-Q1
D. E. Shaw & Co., Inc. trimmed145,068$1M0.3%2026-Q1
BANK OF AMERICA CORP /DE/ trimmed142,131$1M0.3%2026-Q1
STATE OF WISCONSIN INVESTMENT BOARD added116,731$967K0.2%2026-Q1
AMERICAN CENTURY COMPANIES INC trimmed112,353$930K0.2%2026-Q1
RAYMOND JAMES FINANCIAL INC added111,309$922K0.2%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ added100,812$835K0.2%2026-Q1
Nuveen, LLC trimmed100,616$833K0.2%2026-Q1
PANAGORA ASSET MANAGEMENT INC added97,742$809K0.2%2026-Q1
Invesco Ltd. added97,014$803K0.2%2026-Q1
PRUDENTIAL FINANCIAL INC added93,305$773K0.2%2026-Q1
RHUMBLINE ADVISERS trimmed75,965$629K0.1%2026-Q1
ALLIANCEBERNSTEIN L.P. trimmed56,610$543K0.1%2026-Q1
OSAIC HOLDINGS, INC. added63,816$528K0.1%2026-Q1
AWM Investment Company, Inc. added61,111$506K0.1%2026-Q1
MARATHON CAPITAL MANAGEMENT trimmed57,225$474K0.1%2026-Q1
GROUP ONE TRADING LLC trimmed57,104$473K0.1%2026-Q1
Susquehanna Portfolio Strategies, LLC added52,438$434K0.1%2026-Q1
HSBC HOLDINGS PLC51,852$427K0.1%2026-Q1
Evanson Asset Management, LLC50,000$414K0.1%2026-Q1
Geneos Wealth Management Inc. trimmed50,000$414K0.1%2026-Q1
Qube Research & Technologies Ltd added47,490$393K0.1%2026-Q1
Squarepoint Ops LLC trimmed46,927$389K0.1%2026-Q1
SIERRA SUMMIT ADVISORS LLC45,060$373K0.1%2026-Q1
Walleye Trading LLC added44,382$367K0.1%2026-Q1
Quantinno Capital Management LP added43,966$364K0.1%2026-Q1
Creative Planning added43,911$364K0.1%2026-Q1
Campbell & CO Investment Adviser LLC added43,402$359K0.1%2026-Q1
State of Wyoming added42,520$352K0.1%2026-Q1
HARBOR CAPITAL ADVISORS, INC. added42,336$351K0.1%2026-Q1
VANGUARD GROUP INC trimmed2,563,611$25M5.6%2025-Q4 stale
Thematics Asset Management trimmed1,638,623$16M3.5%2025-Q3 stale
AXA Investment Managers S.A. new635,060$6M1.4%2025-Q3 stale
AXA S.A. trimmed735,814$5M1.3%2025-Q2 stale
KENNEDY CAPITAL MANAGEMENT LLC added547,402$4M0.9%2025-Q2 stale
Brandywine Global Investment Management, LLC new114,390$1M0.3%2025-Q4 stale
JACOBS LEVY EQUITY MANAGEMENT, INC trimmed95,498$917K0.2%2025-Q4 stale
LAZARD ASSET MANAGEMENT LLC added93,707$888K0.2%2025-Q3 stale
Divisadero Street Capital Management, LP new93,500$698K0.2%2025-Q2 stale
AlphaQuest LLC added70,562$677K0.2%2025-Q4 stale
SEGALL BRYANT & HAMILL, LLC new68,798$652K0.1%2025-Q3 stale
Point72 Asset Management, L.P. trimmed105,753$643K0.1%2025-Q1 stale
Caption Management, LLC60,004$576K0.1%2025-Q4 stale
Cubist Systematic Strategies, LLC trimmed76,118$568K0.1%2025-Q2 stale
Williams Jones Wealth Management, LLC. trimmed59,089$560K0.1%2025-Q3 stale
Inspire Investing, LLC added48,708$468K0.1%2025-Q4 stale
Legato Capital Management LLC added46,188$443K0.1%2025-Q4 stale
Integrated Quantitative Investments LLC new46,188$443K0.1%2025-Q4 stale
AMERIPRISE FINANCIAL INC trimmed45,094$427K0.1%2025-Q3 stale
Marex Group plc new37,000$355K0.1%2025-Q4 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

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