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Institutional Ownership · SEC Form 13F

Who owns Centessa Pharmaceuticals plc (CNTA)


Which tracked institutional funds hold CNTA, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See CNTA company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

160
Institutional holders
149M
Shares held (tracked funds)
99.6%
Of shares outstanding

How the tape is positioned

100 tracked funds added or opened CNTA while 38 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

CNTA’s largest tracked holder by dollar value, Medicxi Ventures Management (Jersey) Ltd, sizes it at 80.8% of its own reported 13F book, while the median holder sizes it at 0.3% of theirs — a 80.5pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in CNTA divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 160 tracked filers holding CNTA, 98 increased or opened the position and 79 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in CNTA between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 31

  • Pentwater Capital Management LP$325M
  • Paradigm Biocapital Advisors LP$142M
  • ALPINE ASSOCIATES MANAGEMENT INC.$34M
  • BNP PARIBAS ASSET MANAGEMENT Holding S.A.$28M
  • EVENTIDE ASSET MANAGEMENT, LLC$27M
  • TORONTO DOMINION BANK$26M

Full exits 21

  • PRICE T ROWE ASSOCIATES INC /MD/$98M
  • STEMPOINT CAPITAL LP$29M
  • Sofinnova Investments, Inc.$28M
  • Commodore Capital LP$25M
  • ARMISTICE CAPITAL, LLC$13M
  • Walleye Capital LLC$11M

Largest adds

  • Medicxi Ventures Management (Jersey) Ltd$294M
  • Capital World Investors$163M
  • EcoR1 Capital, LLC$160M
  • Index Venture Life Associates VI Ltd$147M
  • MORGAN STANLEY$142M
  • PERCEPTIVE ADVISORS LLC$136M

Largest trims

  • GENERAL ATLANTIC, L.P.$99M
  • Siren, L.L.C.$59M
  • FRANKLIN RESOURCES INC$32M
  • Jain Global LLC$20M
  • MILLENNIUM MANAGEMENT LLC$18M
  • JANE STREET GROUP, LLC$10M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
Medicxi Ventures Management (Jersey) Ltd19,963,157$793M12.9%2026-Q1
Avoro Capital Advisors LLC trimmed11,430,455$454M7.4%2026-Q1
Index Venture Life Associates VI Ltd9,961,789$396M6.4%2026-Q1
ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed8,925,010$355M5.8%2026-Q1
Pentwater Capital Management LP new8,170,000$325M5.3%2026-Q1
FMR LLC trimmed6,852,047$272M4.4%2026-Q1
EcoR1 Capital, LLC added6,000,000$238M3.9%2026-Q1
PERCEPTIVE ADVISORS LLC added5,258,903$209M3.4%2026-Q1
Capital World Investors added4,832,548$192M3.1%2026-Q1
FARALLON CAPITAL MANAGEMENT LLC trimmed4,809,000$191M3.1%2026-Q1
TCG Crossover Management, LLC4,286,480$170M2.8%2026-Q1
MORGAN STANLEY added4,268,353$170M2.8%2026-Q1
Paradigm Biocapital Advisors LP new3,574,048$142M2.3%2026-Q1
JANUS HENDERSON GROUP PLC trimmed3,492,977$139M2.3%2026-Q1
Deep Track Capital, LP added3,158,041$125M2.0%2026-Q1
Logos Global Management LP added2,125,000$84M1.4%2026-Q1
RTW INVESTMENTS, LP added2,054,175$82M1.3%2026-Q1
FEDERATED HERMES, INC. trimmed2,049,439$81M1.3%2026-Q1
BRAIDWELL LP trimmed1,986,768$79M1.3%2026-Q1
BANK OF AMERICA CORP /DE/ added1,932,406$77M1.2%2026-Q1
MAVERICK CAPITAL LTD added1,854,488$74M1.2%2026-Q1
First Light Asset Management, LLC trimmed1,560,991$62M1.0%2026-Q1
Affinity Asset Advisors, LLC added1,400,000$56M0.9%2026-Q1
Foresite Capital Management VI LLC1,364,019$54M0.9%2026-Q1
GENERAL ATLANTIC, L.P. trimmed1,354,830$54M0.9%2026-Q1
GOLDMAN SACHS GROUP INC added1,144,560$45M0.7%2026-Q1
Siren, L.L.C. trimmed1,053,464$42M0.7%2026-Q1
Cormorant Asset Management, LP trimmed1,050,000$42M0.7%2026-Q1
ALPINE ASSOCIATES MANAGEMENT INC. new865,500$34M0.6%2026-Q1
Woodline Partners LP added859,105$34M0.6%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. added852,828$34M0.6%2026-Q1
Octagon Capital Advisors LP750,000$30M0.5%2026-Q1
MILLENNIUM MANAGEMENT LLC trimmed722,121$29M0.5%2026-Q1
BNP PARIBAS ASSET MANAGEMENT Holding S.A. new702,254$28M0.5%2026-Q1
AMERICAN CENTURY COMPANIES INC trimmed687,427$27M0.4%2026-Q1
FRANKLIN RESOURCES INC trimmed684,482$27M0.4%2026-Q1
BAKER BROS. ADVISORS LP670,751$27M0.4%2026-Q1
EVENTIDE ASSET MANAGEMENT, LLC new668,142$27M0.4%2026-Q1
TORONTO DOMINION BANK new654,850$26M0.4%2026-Q1
TIG Advisors, LLC new648,326$26M0.4%2026-Q1
D. E. Shaw & Co., Inc. trimmed643,808$26M0.4%2026-Q1
Bain Capital Life Sciences Investors, LLC new635,000$25M0.4%2026-Q1
Qube Research & Technologies Ltd added628,049$25M0.4%2026-Q1
BlackRock, Inc. added625,420$25M0.4%2026-Q1
CITADEL ADVISORS LLC added598,197$24M0.4%2026-Q1
5AM Venture Management, LLC580,945$23M0.4%2026-Q1
PFM Health Sciences, LP trimmed528,224$21M0.3%2026-Q1
Weiss Asset Management LP new510,407$20M0.3%2026-Q1
Spruce Street Capital LP added489,849$19M0.3%2026-Q1
SILVERARC CAPITAL MANAGEMENT, LLC added466,345$19M0.3%2026-Q1
Trexquant Investment LP added390,951$16M0.3%2026-Q1
UBS Group AG trimmed359,939$14M0.2%2026-Q1
Rock Springs Capital Management LP added351,828$14M0.2%2026-Q1
JPMORGAN CHASE & CO added477,597$13M0.2%2026-Q1
GLAZER CAPITAL, LLC new325,001$13M0.2%2026-Q1
Alyeska Investment Group, L.P. new320,430$13M0.2%2026-Q1
Point72 Asset Management, L.P. trimmed307,355$12M0.2%2026-Q1
ROYCE & ASSOCIATES LP trimmed278,064$11M0.2%2026-Q1
Caption Management, LLC added274,116$11M0.2%2026-Q1
Nantahala Capital Management, LLC254,803$10M0.2%2026-Q1
TD Asset Management Inc trimmed242,044$10M0.2%2026-Q1
HighMark Wealth Management LLC236,785$9M0.2%2026-Q1
Eagle Health Investments LP added214,291$9M0.1%2026-Q1
SummitTX Capital, L.P. trimmed206,847$8M0.1%2026-Q1
DEUTSCHE BANK AG\ added189,961$8M0.1%2026-Q1
RENAISSANCE TECHNOLOGIES LLC trimmed185,000$7M0.1%2026-Q1
Schonfeld Strategic Advisors LLC trimmed171,933$7M0.1%2026-Q1
T. Rowe Price Investment Management, Inc. added170,016$7M0.1%2026-Q1
MARSHALL WACE, LLP trimmed168,177$7M0.1%2026-Q1
FRED ALGER MANAGEMENT, LLC added168,170$7M0.1%2026-Q1
Holocene Advisors, LP added160,942$6M0.1%2026-Q1
Atom Investors LP added158,509$6M0.1%2026-Q1
Burkehill Global Management, LP150,000$6M0.1%2026-Q1
PLATINUM INVESTMENT MANAGEMENT LTD trimmed137,741$5M0.1%2026-Q1
LMR Partners LLP new125,000$5M0.1%2026-Q1
HRT FINANCIAL LP added116,992$5M0.1%2026-Q1
VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed111,956$4M0.1%2026-Q1
Freestone Grove Partners LP new109,327$4M0.1%2026-Q1
Legal & General Group Plc added110,207$4M0.1%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added107,778$4M0.1%2026-Q1
AQR Arbitrage LLC new98,028$4M0.1%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ trimmed3,927,343$98M1.6%2025-Q4 stale
STEMPOINT CAPITAL LP added1,154,114$29M0.5%2025-Q4 stale
Sofinnova Investments, Inc. new1,104,274$28M0.4%2025-Q4 stale
Commodore Capital LP trimmed1,000,000$25M0.4%2025-Q4 stale
Tanager Wealth Management LLP598,044$15M0.2%2025-Q3 stale
Ensign Peak Advisors, Inc559,744$14M0.2%2025-Q3 stale
Polar Capital Holdings Plc added1,000,000$13M0.2%2025-Q2 stale
Driehaus Capital Management LLC added515,979$13M0.2%2025-Q3 stale
ARMISTICE CAPITAL, LLC added500,000$13M0.2%2025-Q4 stale
Walleye Capital LLC added441,160$11M0.2%2025-Q4 stale
Avidity Partners Management LP trimmed529,000$8M0.1%2025-Q1 stale
Saturn V Capital Management LP trimmed282,692$7M0.1%2025-Q4 stale
LORD, ABBETT & CO. LLC added446,196$6M0.1%2025-Q1 stale
WCM INVESTMENT MANAGEMENT, LLC new257,190$6M0.1%2025-Q4 stale
Cutter Capital Management, LP added418,127$6M0.1%2025-Q1 stale
TANG CAPITAL MANAGEMENT LLC added200,000$5M0.1%2025-Q3 stale
Wildcat Capital Management, LLC new281,859$4M0.1%2025-Q1 stale
Windmill Hill Asset Management Ltd163,768$4M0.1%2025-Q3 stale
Ally Bridge Group (NY) LLC added293,986$4M0.1%2025-Q2 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership