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Institutional Ownership · SEC Form 13F

Who owns C4 Therapeutics, Inc. (CCCC)


Which tracked institutional funds hold CCCC, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See CCCC company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

125
Institutional holders
85M
Shares held (tracked funds)
87.3%
Of shares outstanding

How the tape is positioned

The tracked-fund tape on CCCC is one-sided between 2025-Q4 and 2026-Q1: 37 added or opened and 5 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

CCCC’s largest tracked holder by dollar value, MORGAN STANLEY, sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes CCCC more heavily than its largest holder by dollar value does.

Book-share is each fund’s reported value in CCCC divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 123 tracked filers holding CCCC, 74 increased or opened the position and 43 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in CCCC between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 8

  • VANGUARD CAPITAL MANAGEMENT LLC$10M
  • Squadron Capital Management LLC$6M
  • CONGRESS ASSET MANAGEMENT CO$2M
  • VANGUARD FIDUCIARY TRUST CO$1M
  • STEMPOINT CAPITAL LP$1M
  • PLATINUM INVESTMENT MANAGEMENT LTD$1M

Full exits 2

  • VANGUARD GROUP INC$8M
  • TWO SIGMA ADVISERS, LP$2M

Largest adds

  • JPMORGAN CHASE & CO$8M
  • MORGAN STANLEY$7M
  • RA CAPITAL MANAGEMENT, L.P.$6M
  • CITADEL ADVISORS LLC$6M
  • Bain Capital Life Sciences Investors, LLC$5M
  • TWO SIGMA INVESTMENTS, LP$5M

Largest trims

  • Point72 Asset Management, L.P.$18M
  • WASATCH ADVISORS LP$509K
  • ORBIMED ADVISORS LLC$431K

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
MORGAN STANLEY added9,072,400$24M9.9%2026-Q1
RA CAPITAL MANAGEMENT, L.P.8,000,000$21M8.7%2026-Q1
Bain Capital Life Sciences Investors, LLC7,171,910$19M7.8%2026-Q1
Lynx1 Capital Management LP trimmed6,998,902$18M7.6%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new3,861,852$10M4.2%2026-Q1
Soleus Capital Management, L.P.3,803,942$10M4.1%2026-Q1
TWO SIGMA INVESTMENTS, LP added3,035,634$8M3.3%2026-Q1
WASATCH ADVISORS LP trimmed2,961,761$8M3.2%2026-Q1
JPMORGAN CHASE & CO added3,223,054$8M3.1%2026-Q1
CITADEL ADVISORS LLC added2,511,015$7M2.7%2026-Q1
RENAISSANCE TECHNOLOGIES LLC added2,461,815$6M2.7%2026-Q1
GOLDMAN SACHS GROUP INC added2,387,378$6M2.6%2026-Q1
BANK OF AMERICA CORP /DE/ trimmed2,359,241$6M2.6%2026-Q1
Squadron Capital Management LLC new2,250,000$6M2.4%2026-Q1
BlackRock, Inc. added2,048,526$5M2.2%2026-Q1
SILVERARC CAPITAL MANAGEMENT, LLC trimmed1,911,785$5M2.1%2026-Q1
ACADIAN ASSET MANAGEMENT LLC added1,890,914$5M2.1%2026-Q1
MILLENNIUM MANAGEMENT LLC added1,393,342$4M1.5%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed1,286,840$3M1.4%2026-Q1
JANE STREET GROUP, LLC added1,246,896$3M1.4%2026-Q1
D. E. Shaw & Co., Inc. added1,048,210$3M1.1%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC trimmed951,043$3M1.0%2026-Q1
WELLS FARGO & COMPANY/MN added867,911$2M0.9%2026-Q1
ORBIMED ADVISORS LLC trimmed856,353$2M0.9%2026-Q1
CONGRESS ASSET MANAGEMENT CO new830,624$2M0.9%2026-Q1
Qube Research & Technologies Ltd added752,114$2M0.8%2026-Q1
VANGUARD FIDUCIARY TRUST CO new484,131$1M0.5%2026-Q1
STEMPOINT CAPITAL LP new453,236$1M0.5%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added452,228$1M0.5%2026-Q1
DIMENSIONAL FUND ADVISORS LP added442,518$1M0.5%2026-Q1
PLATINUM INVESTMENT MANAGEMENT LTD new384,766$1M0.4%2026-Q1
STATE STREET CORP added382,973$1M0.4%2026-Q1
BARCLAYS PLC added317,877$836K0.3%2026-Q1
683 Capital Management, LLC trimmed300,000$789K0.3%2026-Q1
Connor, Clark & Lunn Investment Management Ltd. added277,183$729K0.3%2026-Q1
FMR LLC added272,368$716K0.3%2026-Q1
JACOBS LEVY EQUITY MANAGEMENT, INC trimmed264,620$696K0.3%2026-Q1
Susquehanna Portfolio Strategies, LLC trimmed260,279$685K0.3%2026-Q1
Man Group plc added256,468$675K0.3%2026-Q1
LPL Financial LLC added246,800$649K0.3%2026-Q1
Invesco Ltd. trimmed244,507$643K0.3%2026-Q1
Walleye Capital LLC trimmed239,118$629K0.3%2026-Q1
Hennion & Walsh Asset Management, Inc. trimmed223,168$587K0.2%2026-Q1
UBS Group AG added215,877$568K0.2%2026-Q1
BNP PARIBAS FINANCIAL MARKETS added190,348$501K0.2%2026-Q1
NORTHERN TRUST CORP added189,479$498K0.2%2026-Q1
TORONTO DOMINION BANK new174,663$459K0.2%2026-Q1
Point72 Asset Management, L.P. trimmed169,096$445K0.2%2026-Q1
MARSHALL WACE, LLP trimmed155,495$409K0.2%2026-Q1
Atom Investors LP added136,047$358K0.1%2026-Q1
CANADA PENSION PLAN INVESTMENT BOARD added135,600$357K0.1%2026-Q1
BRIDGEWAY CAPITAL MANAGEMENT, LLC131,100$345K0.1%2026-Q1
Hudson Bay Capital Management LP added130,081$342K0.1%2026-Q1
Mariner, LLC trimmed127,517$334K0.1%2026-Q1
Verdad Advisers, LP new109,407$288K0.1%2026-Q1
Brevan Howard Capital Management LP added92,647$244K0.1%2026-Q1
PANAGORA ASSET MANAGEMENT INC trimmed86,760$228K0.1%2026-Q1
AXQ CAPITAL, LP new86,278$227K0.1%2026-Q1
AMERICAN CENTURY COMPANIES INC added85,444$225K0.1%2026-Q1
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group85,000$224K0.1%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ added71,546$189K0.1%2026-Q1
Crestwood Advisors Group, LLC66,536$175K0.1%2026-Q1
Quadrature Capital Ltd trimmed62,760$165K0.1%2026-Q1
Jain Global LLC added62,390$164K0.1%2026-Q1
INTREPID FAMILY OFFICE LLC added60,000$158K0.1%2026-Q1
OMERS ADMINISTRATION Corp trimmed59,700$157K0.1%2026-Q1
Seven Fleet Capital Management LP new57,076$150K0.1%2026-Q1
READYSTATE ASSET MANAGEMENT LP new49,586$130K0.1%2026-Q1
ExodusPoint Capital Management, LP trimmed47,507$125K0.1%2026-Q1
XTX Topco Ltd trimmed47,151$124K0.1%2026-Q1
ADAR1 Capital Management, LLC new43,000$113K0.0%2026-Q1
CITIGROUP INC trimmed42,428$112K0.0%2026-Q1
Squarepoint Ops LLC trimmed40,664$107K0.0%2026-Q1
Focus Partners Wealth38,187$100K0.0%2026-Q1
Diametric Capital, LP new34,594$91K0.0%2026-Q1
Vanguard Global Advisers, LLC new33,832$89K0.0%2026-Q1
PRELUDE CAPITAL MANAGEMENT, LLC added30,957$81K0.0%2026-Q1
FARALLON CAPITAL MANAGEMENT LLC28,000$74K0.0%2026-Q1
Jefferies Financial Group Inc. trimmed26,120$69K0.0%2026-Q1
VANGUARD GROUP INC added4,379,815$8M3.5%2025-Q4 stale
SAMLYN CAPITAL, LLC trimmed3,015,139$5M2.0%2025-Q1 stale
TWO SIGMA ADVISERS, LP added1,068,200$2M0.8%2025-Q4 stale
TANG CAPITAL MANAGEMENT LLC900,000$2M0.8%2025-Q3 stale
Shay Capital LLC added420,000$932K0.4%2025-Q3 stale
SG Americas Securities, LLC added425,096$680K0.3%2025-Q1 stale
AQR CAPITAL MANAGEMENT LLC added383,789$549K0.2%2025-Q2 stale
ArrowMark Colorado Holdings LLC204,505$391K0.2%2025-Q4 stale
Nuveen, LLC new192,424$308K0.1%2025-Q1 stale
Cubist Systematic Strategies, LLC trimmed138,657$308K0.1%2025-Q3 stale
ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed200,000$286K0.1%2025-Q2 stale
ALGERT GLOBAL LLC added106,300$236K0.1%2025-Q3 stale
Bank of New York Mellon Corp added141,284$226K0.1%2025-Q1 stale
State of Wyoming added82,509$183K0.1%2025-Q3 stale
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC67,617$129K0.1%2025-Q4 stale
Aster Capital Management (DIFC) Ltd new77,734$111K0.0%2025-Q2 stale
INTECH INVESTMENT MANAGEMENT LLC added53,606$86K0.0%2025-Q1 stale
ALLIANCEBERNSTEIN L.P.47,800$76K0.0%2025-Q1 stale
Y-Intercept (Hong Kong) Ltd added52,521$75K0.0%2025-Q2 stale
GROUP ONE TRADING LLC added38,994$74K0.0%2025-Q4 stale
DEUTSCHE BANK AG\ added46,225$74K0.0%2025-Q1 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership