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Institutional Ownership · SEC Form 13F

Who owns C4 Therapeutics (CCCC)


Which tracked institutional funds hold CCCC, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See CCCC company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

145
Institutional holders
116M
Shares held (tracked funds)

How the tape is positioned

The tracked-fund tape on CCCC is one-sided between 2026-Q1 and 2026-Q2: 62 added or opened and 11 trimmed or exited — on balance accumulating.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

CCCC’s largest tracked holder by dollar value, MORGAN STANLEY, sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes CCCC more heavily than its largest holder by dollar value does.

Book-share is each fund’s reported value in CCCC divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 145 tracked filers holding CCCC, 102 increased or opened the position and 53 reduced or closed it; over the same quarter, there were no open-market insider Form 4s.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in CCCC between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 16

  • Ikarian Capital, LLC$11M
  • Candriam S.C.A.$8M
  • Patient Square Capital LP$8M
  • HighVista Strategies LLC$6M
  • BOOTHBAY FUND MANAGEMENT, LLC$3M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$3M

Full exits 5

  • ACADIAN ASSET MANAGEMENT LLC$5M
  • ORBIMED ADVISORS LLC$2M
  • 683 Capital Management, LLC$789K
  • HRT FINANCIAL LP$719K
  • Hennion & Walsh Asset Management, Inc.$587K

Largest adds

  • BlackRock, Inc.$31M
  • Squadron Capital Management LLC$28M
  • MORGAN STANLEY$18M
  • RA CAPITAL MANAGEMENT, L.P.$16M
  • Lynx1 Capital Management LP$16M
  • Bain Capital Life Sciences Investors, LLC$15M

Largest trims

  • MILLENNIUM MANAGEMENT LLC$3M
  • JANE STREET GROUP, LLC$2M
  • RENAISSANCE TECHNOLOGIES LLC$918K
  • JACOBS LEVY EQUITY MANAGEMENT, INC$579K
  • BARCLAYS PLC$488K
  • TORONTO DOMINION BANK$456K

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
MORGAN STANLEY trimmed8,867,338$41M7.7%2026-Q2
RA CAPITAL MANAGEMENT, L.P.8,000,000$37M7.0%2026-Q2
BlackRock, Inc. added7,896,718$37M6.9%2026-Q2
Lynx1 Capital Management LP added7,326,691$34M6.4%2026-Q2
Squadron Capital Management LLC added7,200,000$34M6.3%2026-Q2
Bain Capital Life Sciences Investors, LLC7,171,910$33M6.2%2026-Q2
JPMORGAN CHASE & CO added4,747,424$21M3.8%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added4,417,731$21M3.8%2026-Q2
CITADEL ADVISORS LLC added4,187,580$20M3.6%2026-Q2
GOLDMAN SACHS GROUP INC added3,530,991$16M3.1%2026-Q2
WASATCH ADVISORS LP added3,522,644$16M3.1%2026-Q2
TWO SIGMA INVESTMENTS, LP added3,469,707$16M3.0%2026-Q2
Soleus Capital Management, L.P. trimmed3,377,981$16M2.9%2026-Q2
SILVERARC CAPITAL MANAGEMENT, LLC added3,032,060$14M2.6%2026-Q2
BANK OF AMERICA CORP /DE/ added2,656,359$12M2.3%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added2,522,163$12M2.2%2026-Q2
Ikarian Capital, LLC new2,433,000$11M2.1%2026-Q2
STATE STREET CORP added2,115,621$10M1.8%2026-Q2
Candriam S.C.A. new1,796,937$8M1.6%2026-Q2
D. E. Shaw & Co., Inc. added1,740,989$8M1.5%2026-Q2
SUSQUEHANNA INTERNATIONAL GROUP, LLP added1,732,210$8M1.5%2026-Q2
Patient Square Capital LP new1,608,815$8M1.4%2026-Q2
HighVista Strategies LLC new1,348,136$6M1.2%2026-Q2
RENAISSANCE TECHNOLOGIES LLC trimmed1,189,828$6M1.0%2026-Q2
DIMENSIONAL FUND ADVISORS LP added1,188,507$6M1.0%2026-Q2
NORTHERN TRUST CORP added1,160,547$5M1.0%2026-Q2
CONGRESS ASSET MANAGEMENT CO added1,003,437$5M0.9%2026-Q2
FMR LLC added894,054$4M0.8%2026-Q2
UBS Group AG added828,970$4M0.7%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added781,060$4M0.7%2026-Q2
BOOTHBAY FUND MANAGEMENT, LLC new736,331$3M0.6%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC new680,094$3M0.6%2026-Q2
VANGUARD FIDUCIARY TRUST CO added609,146$3M0.5%2026-Q2
ExodusPoint Capital Management, LP added580,195$3M0.5%2026-Q2
Velan Capital Investment Management LP new570,000$3M0.5%2026-Q2
STEMPOINT CAPITAL LP added523,648$2M0.5%2026-Q2
Rockefeller Capital Management L.P. new495,817$2M0.4%2026-Q2
Nuveen, LLC added484,010$2M0.4%2026-Q2
WELLS FARGO & COMPANY/MN trimmed452,701$2M0.4%2026-Q2
Man Group plc added408,648$2M0.4%2026-Q2
PLATINUM INVESTMENT MANAGEMENT LTD384,766$2M0.3%2026-Q2
Seven Fleet Capital Management LP added381,169$2M0.3%2026-Q2
Qube Research & Technologies Ltd trimmed370,554$2M0.3%2026-Q2
Atom Investors LP added364,351$2M0.3%2026-Q2
Susquehanna Portfolio Strategies, LLC added335,079$2M0.3%2026-Q2
ADAGE CAPITAL PARTNERS GP, L.L.C. added325,000$2M0.3%2026-Q2
JANE STREET GROUP, LLC trimmed302,750$1M0.3%2026-Q2
Connor, Clark & Lunn Investment Management Ltd. added300,734$1M0.3%2026-Q2
ADAR1 Capital Management, LLC added291,957$1M0.3%2026-Q2
Invesco Ltd. added290,226$1M0.3%2026-Q2
PANAGORA ASSET MANAGEMENT INC added264,947$1M0.2%2026-Q2
LPL Financial LLC added253,165$1M0.2%2026-Q2
Bank of New York Mellon Corp added249,517$1M0.2%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP trimmed227,768$1M0.2%2026-Q2
MARSHALL WACE, LLP added227,003$1M0.2%2026-Q2
MILLENNIUM MANAGEMENT LLC trimmed215,386$1M0.2%2026-Q2
Jump Financial, LLC added182,700$853K0.2%2026-Q2
Point72 Asset Management, L.P. added173,965$812K0.2%2026-Q2
Squarepoint Ops LLC added170,834$798K0.1%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ added155,881$728K0.1%2026-Q2
Headlands Technologies LLC new153,972$719K0.1%2026-Q2
AMERICAN CENTURY COMPANIES INC added150,681$704K0.1%2026-Q2
XTX Topco Ltd added135,438$632K0.1%2026-Q2
Palumbo Wealth Management LLC new132,417$618K0.1%2026-Q2
RHUMBLINE ADVISERS added131,877$616K0.1%2026-Q2
BRIDGEWAY CAPITAL MANAGEMENT, LLC131,100$612K0.1%2026-Q2
Walleye Capital LLC trimmed115,125$538K0.1%2026-Q2
ALPS ADVISORS INC new112,214$524K0.1%2026-Q2
CANADA PENSION PLAN INVESTMENT BOARD trimmed101,500$474K0.1%2026-Q2
DEUTSCHE BANK AG\ added98,873$462K0.1%2026-Q2
Verition Fund Management LLC added95,000$444K0.1%2026-Q2
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group85,000$397K0.1%2026-Q2
Aster Capital Management (DIFC) Ltd77,734$111K0.0%2026-Q2
BARCLAYS PLC trimmed74,516$348K0.1%2026-Q2
BNP PARIBAS FINANCIAL MARKETS trimmed74,373$347K0.1%2026-Q2
Crestwood Advisors Group, LLC66,536$311K0.1%2026-Q2
CV Advisors LLC new65,000$304K0.1%2026-Q2
INTREPID FAMILY OFFICE LLC added65,000$304K0.1%2026-Q2
ALLIANCEBERNSTEIN L.P. added64,780$170K0.0%2026-Q2
MetLife Investment Management, LLC added61,393$287K0.1%2026-Q2
Jain Global LLC trimmed57,562$269K0.1%2026-Q2
CITIGROUP INC added49,389$231K0.0%2026-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. added46,474$217K0.0%2026-Q2
SEI INVESTMENTS CO added42,376$198K0.0%2026-Q2
Quadrature Capital Ltd trimmed36,726$172K0.0%2026-Q2
Caption Management, LLC new35,000$163K0.0%2026-Q2
Vanguard Global Advisers, LLC33,832$158K0.0%2026-Q2
Dynamic Technology Lab Private Ltd added32,828$153K0.0%2026-Q2
PRUDENTIAL FINANCIAL INC added31,235$146K0.0%2026-Q2
Police & Firemen's Retirement System of New Jersey added29,893$140K0.0%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE added27,513$128K0.0%2026-Q2
JACOBS LEVY EQUITY MANAGEMENT, INC trimmed25,111$117K0.0%2026-Q2
Cresset Asset Management, LLC25,000$117K0.0%2026-Q2
NEW YORK STATE COMMON RETIREMENT FUND added24,100$113K0.0%2026-Q2
StoneX Group Inc. new22,420$102K0.0%2026-Q2
GROUP ONE TRADING LLC trimmed21,773$102K0.0%2026-Q2
Corient Private Wealth LP21,387$100K0.0%2026-Q2
Scientech Research LLC new21,260$99K0.0%2026-Q2
Quantbot Technologies LP new20,827$97K0.0%2026-Q2
PRELUDE CAPITAL MANAGEMENT, LLC trimmed19,700$92K0.0%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership