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Institutional Ownership · SEC Form 13F

Who owns Crescent Biopharma (CBIO)


Which tracked institutional funds hold CBIO, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See CBIO company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

80
Institutional holders
29M
Shares held (tracked funds)

How the tape is positioned

23 tracked funds added or opened CBIO while 20 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

CBIO’s largest tracked holder by dollar value, FMR LLC, sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in CBIO divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 80 tracked filers holding CBIO, 49 increased or opened the position and 26 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in CBIO between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 10

  • Remedium Capital Partners, LLC$7M
  • AMERIPRISE FINANCIAL INC$5M
  • VANGUARD PORTFOLIO MANAGEMENT LLC$3M
  • STEMPOINT CAPITAL LP$3M
  • SECTORAL ASSET MANAGEMENT INC$2M
  • Blackstone Inc.$1M

Full exits 5

  • Deep Track Capital, LP$8M
  • Alyeska Investment Group, L.P.$5M
  • GOLDMAN SACHS GROUP INC$4M
  • SUSQUEHANNA INTERNATIONAL GROUP, LLP$4M
  • Hudson Bay Capital Management LP$2M

Largest adds

  • Logos Global Management LP$25M
  • BlackRock, Inc.$21M
  • GEODE CAPITAL MANAGEMENT, LLC$5M
  • STATE STREET CORP$5M
  • JENNISON ASSOCIATES LLC$4M
  • BALYASNY ASSET MANAGEMENT L.P.$2M

Largest trims

  • FMR LLC$2M
  • SILVERARC CAPITAL MANAGEMENT, LLC$1M
  • BVF INC/IL$1M
  • Fairmount Funds Management LLC$1M
  • VANGUARD CAPITAL MANAGEMENT LLC$902K
  • Stonepine Capital Management, LLC$841K

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
FMR LLC4,133,514$74M12.5%2026-Q2
BVF INC/IL2,748,763$49M8.3%2026-Q2
Fairmount Funds Management LLC2,747,866$49M8.3%2026-Q2
Venrock Adviser, LLC2,133,576$38M6.4%2026-Q2
Logos Global Management LP added1,900,000$34M5.7%2026-Q2
FCPM III SERVICES B.V.1,677,852$30M5.1%2026-Q2
BALYASNY ASSET MANAGEMENT L.P. added1,662,917$30M5.0%2026-Q2
Vestal Point Capital, LP added1,630,000$29M4.9%2026-Q2
Opaleye Management Inc. added1,319,351$24M4.0%2026-Q2
BlackRock, Inc. added1,271,762$23M3.8%2026-Q2
TANG CAPITAL MANAGEMENT LLC1,160,000$21M3.5%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC trimmed767,755$14M2.3%2026-Q2
MILLENNIUM MANAGEMENT LLC added403,859$7M1.2%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added384,576$7M1.2%2026-Q2
JENNISON ASSOCIATES LLC added378,507$7M1.1%2026-Q2
RTW INVESTMENTS, LP372,856$7M1.1%2026-Q2
NEXTBio Capital Management LP372,856$7M1.1%2026-Q2
Remedium Capital Partners, LLC new361,250$7M1.1%2026-Q2
STATE STREET CORP added315,587$6M1.0%2026-Q2
AMERIPRISE FINANCIAL INC new302,568$5M0.9%2026-Q2
Point72 Asset Management, L.P.300,000$5M0.9%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ trimmed275,581$5M0.8%2026-Q2
MARSHALL WACE, LLP added214,300$4M0.6%2026-Q2
PERCEPTIVE ADVISORS LLC206,942$4M0.6%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC new188,803$3M0.6%2026-Q2
TWO SIGMA INVESTMENTS, LP added186,874$3M0.6%2026-Q2
STEMPOINT CAPITAL LP new182,382$3M0.6%2026-Q2
UBS Group AG added175,182$3M0.5%2026-Q2
NORTHERN TRUST CORP added138,778$2M0.4%2026-Q2
Exome Asset Management LLC trimmed127,769$2M0.4%2026-Q2
SECTORAL ASSET MANAGEMENT INC new121,300$2M0.4%2026-Q2
Woodline Partners LP added94,488$2M0.3%2026-Q2
VANGUARD FIDUCIARY TRUST CO added75,225$1M0.2%2026-Q2
Burkehill Global Management, LP74,000$1M0.2%2026-Q2
Blackstone Inc. trimmed62,647$1M0.2%2026-Q2
SILVERARC CAPITAL MANAGEMENT, LLC trimmed59,104$1M0.2%2026-Q2
Y-Intercept (Hong Kong) Ltd new50,824$915K0.2%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC new50,258$905K0.2%2026-Q2
Nuveen, LLC new47,629$857K0.1%2026-Q2
Bank of New York Mellon Corp new45,778$824K0.1%2026-Q2
Stonepine Capital Management, LLC trimmed40,000$720K0.1%2026-Q2
BANK OF AMERICA CORP /DE/ trimmed25,821$465K0.1%2026-Q2
RHUMBLINE ADVISERS new25,487$459K0.1%2026-Q2
MOORE CAPITAL MANAGEMENT, LP25,000$450K0.1%2026-Q2
Squarepoint Ops LLC new24,166$435K0.1%2026-Q2
AMERICAN CENTURY COMPANIES INC new22,805$410K0.1%2026-Q2
WELLS FARGO & COMPANY/MN new19,700$355K0.1%2026-Q2
ADAR1 Capital Management, LLC trimmed18,275$329K0.1%2026-Q2
Virtus Investment Advisers, LLC new18,258$329K0.1%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed17,755$320K0.1%2026-Q2
MORGAN STANLEY trimmed17,698$319K0.1%2026-Q2
WELLINGTON MANAGEMENT GROUP LLP trimmed14,600$263K0.0%2026-Q2
BANK OF MONTREAL /CAN/ new13,768$248K0.0%2026-Q2
MetLife Investment Management, LLC new12,780$230K0.0%2026-Q2
Invesco Ltd. new11,731$211K0.0%2026-Q2
Persistent Asset Partners Ltd new10,968$197K0.0%2026-Q2
XTX Topco Ltd new10,564$190K0.0%2026-Q2
CITIGROUP INC trimmed10,141$183K0.0%2026-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. new9,901$178K0.0%2026-Q2
JPMORGAN CHASE & CO trimmed9,020$162K0.0%2026-Q2
NEW YORK STATE COMMON RETIREMENT FUND new7,600$137K0.0%2026-Q2
Police & Firemen's Retirement System of New Jersey new6,369$115K0.0%2026-Q2
BARCLAYS PLC trimmed4,462$80K0.0%2026-Q2
BNP PARIBAS FINANCIAL MARKETS trimmed3,303$59K0.0%2026-Q2
Vanguard Global Advisers, LLC trimmed2,714$49K0.0%2026-Q2
Legal & General Group Plc new2,097$38K0.0%2026-Q2
Tower Research Capital LLC (TRC) added1,761$32K0.0%2026-Q2
Russell Investments Group, Ltd. new1,726$31K0.0%2026-Q2
ROYAL BANK OF CANADA added681$12K0.0%2026-Q2
US BANCORP \DE\ new403$7K0.0%2026-Q2
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM new297$5K0.0%2026-Q2
Parallel Advisors, LLC264$5K0.0%2026-Q2
Allworth Financial LP161$3K0.0%2026-Q2
Sterling Capital Management LLC new76$1K0.0%2026-Q2
SBI Securities Co., Ltd.68$1K0.0%2026-Q2
Fortitude Family Office, LLC40$7200.0%2026-Q2
Quarry LP new29$5220.0%2026-Q2
OSAIC HOLDINGS, INC.26$4680.0%2026-Q2
Caitong International Asset Management Co., Ltd added21$3780.0%2026-Q2
NATIONAL BANK OF CANADA /FI/ new3$540.0%2026-Q2
Deep Track Capital, LP453,686$8M1.4%2026-Q1 stale (1 quarter behind)
Alyeska Investment Group, L.P.264,000$5M0.8%2026-Q1 stale (1 quarter behind)
GOLDMAN SACHS GROUP INC added228,475$4M0.7%2026-Q1 stale (1 quarter behind)
SUSQUEHANNA INTERNATIONAL GROUP, LLP added213,635$4M0.7%2026-Q1 stale (1 quarter behind)
Hudson Bay Capital Management LP new88,867$2M0.3%2026-Q1 stale (1 quarter behind)
Lighthouse Investment Partners, LLC new25,000$459K0.1%2026-Q1 stale (1 quarter behind)
RENAISSANCE TECHNOLOGIES LLC trimmed24,262$446K0.1%2026-Q1 stale (1 quarter behind)
Brevan Howard Capital Management LP new19,530$359K0.1%2026-Q1 stale (1 quarter behind)
VANGUARD GROUP INC trimmed557,506$7M1.1%2025-Q4 stale (2 quarters behind)
Boxer Capital Management, LLC453,686$5M0.9%2025-Q4 stale (2 quarters behind)
Driehaus Capital Management LLC302,457$4M0.6%2025-Q4 stale (2 quarters behind)
HEIGHTS CAPITAL MANAGEMENT, INC new264,000$3M0.5%2025-Q4 stale (2 quarters behind)
Jefferies Financial Group Inc. trimmed64,244$762K0.1%2025-Q4 stale (2 quarters behind)
TWO SIGMA ADVISERS, LP new32,500$385K0.1%2025-Q4 stale (2 quarters behind)
Commodore Capital LP trimmed450,829$5M0.9%2025-Q3 stale (3 quarters behind)
Frazier Life Sciences Management, L.P. trimmed272,951$3M0.5%2025-Q3 stale (3 quarters behind)
ADAGE CAPITAL PARTNERS GP, L.L.C. added200,005$2M0.4%2025-Q3 stale (3 quarters behind)
Soleus Capital Management, L.P. trimmed200,000$2M0.4%2025-Q3 stale (3 quarters behind)
Paradigm Biocapital Advisors LP new642,721$10M1.7%2025-Q2 stale (4 quarters behind)
BRAIDWELL LP new261,504$4M0.7%2025-Q2 stale (4 quarters behind)

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership