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Institutional Ownership · SEC Form 13F

Who owns Bicycle Therapeutics (BCYC)


Which tracked institutional funds hold BCYC, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See BCYC company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

99
Institutional holders
35M
Shares held (tracked funds)
50.7%
Of shares outstanding

How the tape is positioned

10 tracked funds added or opened BCYC while 13 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

BCYC’s largest tracked holder by dollar value, BAKER BROS. ADVISORS LP, sizes it at 0.2% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.2pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in BCYC divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 99 tracked filers holding BCYC, 49 increased or opened the position and 35 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in BCYC between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 1

  • Sculptor Capital LP$839K

Full exits 6

  • ACADIAN ASSET MANAGEMENT LLC$9M
  • Siren, L.L.C.$7M
  • PRINCIPAL FINANCIAL GROUP INC$5M
  • SILVERCREST ASSET MANAGEMENT GROUP LLC$2M
  • PLATINUM INVESTMENT MANAGEMENT LTD$857K
  • Marex Group plc$534K

Largest adds

  • RENAISSANCE TECHNOLOGIES LLC$2M
  • Qube Research & Technologies Ltd$2M
  • Peapod Lane Capital LLC$2M
  • MARSHALL WACE, LLP$2M
  • TWO SIGMA INVESTMENTS, LP$1M
  • MILLENNIUM MANAGEMENT LLC$1M

Largest trims

  • BAKER BROS. ADVISORS LP$4M
  • FCPM III SERVICES B.V.$1M
  • ARMISTICE CAPITAL, LLC$1M
  • Long Focus Capital Management, LLC$1M
  • PRICE T ROWE ASSOCIATES INC /MD/$946K
  • Birchview Capital, LP$821K

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
BAKER BROS. ADVISORS LP10,885,357$46M27.1%2026-Q2
FCPM III SERVICES B.V.3,468,430$15M8.6%2026-Q2
ARMISTICE CAPITAL, LLC3,398,000$14M8.4%2026-Q2
Long Focus Capital Management, LLC3,310,687$14M8.2%2026-Q2
RENAISSANCE TECHNOLOGIES LLC added1,533,400$7M3.8%2026-Q2
GSK plc1,529,561$6M3.8%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ trimmed902,150$4M2.2%2026-Q2
MARSHALL WACE, LLP added797,940$3M2.0%2026-Q2
Qube Research & Technologies Ltd added775,567$3M1.9%2026-Q2
MORGAN STANLEY added667,269$3M1.7%2026-Q2
SCHRODER INVESTMENT MANAGEMENT GROUP615,833$3M1.5%2026-Q2
CITADEL ADVISORS LLC added554,225$2M1.4%2026-Q2
MILLENNIUM MANAGEMENT LLC added553,967$2M1.4%2026-Q2
Peapod Lane Capital LLC added537,978$2M1.3%2026-Q2
DIADEMA PARTNERS LP trimmed462,724$2M1.2%2026-Q2
TWO SIGMA INVESTMENTS, LP added434,577$2M1.1%2026-Q2
JANE STREET GROUP, LLC added392,163$2M1.0%2026-Q2
Birchview Capital, LP trimmed313,616$1M0.8%2026-Q2
BlackRock, Inc. added280,386$1M0.7%2026-Q2
MOORE CAPITAL MANAGEMENT, LP275,000$1M0.7%2026-Q2
Rangeley Capital, LLC added253,500$1M0.6%2026-Q2
FLAX POND CAPITAL, LLC added196,136$910K0.5%2026-Q2
Palo Alto Investors LP201,890$856K0.5%2026-Q2
Sculptor Capital LP new197,904$839K0.5%2026-Q2
Eversept Partners, LP190,715$809K0.5%2026-Q2
PINNACLE ASSOCIATES LTD added189,990$806K0.5%2026-Q2
Jump Financial, LLC added167,100$709K0.4%2026-Q2
Point72 Asset Management, L.P. added149,936$636K0.4%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE127,863$542K0.3%2026-Q2
GOLDMAN SACHS GROUP INC added121,281$514K0.3%2026-Q2
Persistent Asset Partners Ltd trimmed117,254$497K0.3%2026-Q2
XTX Topco Ltd added109,801$466K0.3%2026-Q2
Quadrature Capital Ltd added104,092$441K0.3%2026-Q2
TD Asset Management Inc91,992$390K0.2%2026-Q2
Virtus Investment Advisers, LLC added80,789$343K0.2%2026-Q2
NANO CAP NEW MILLENNIUM GROWTH FUND L P new80,000$339K0.2%2026-Q2
EntryPoint Capital, LLC added77,743$330K0.2%2026-Q2
Marquette Asset Management, LLC new72,854$309K0.2%2026-Q2
DAFNA Capital Management LLC64,492$273K0.2%2026-Q2
State of Tennessee, Department of Treasury61,153$259K0.2%2026-Q2
SEI INVESTMENTS CO52,784$224K0.1%2026-Q2
ALPS ADVISORS INC added51,122$217K0.1%2026-Q2
Verdad Advisers, LP new51,100$217K0.1%2026-Q2
ADAR1 Capital Management, LLC trimmed50,638$215K0.1%2026-Q2
SIMPLEX TRADING, LLC added35,232$149K0.1%2026-Q2
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed31,957$135K0.1%2026-Q2
Trexquant Investment LP new31,044$132K0.1%2026-Q2
STATE STREET CORP added30,829$131K0.1%2026-Q2
WOODSTOCK CORP29,146$124K0.1%2026-Q2
AXQ CAPITAL, LP trimmed27,368$116K0.1%2026-Q2
D. E. Shaw & Co., Inc. added25,457$108K0.1%2026-Q2
Invesco Ltd. added24,802$105K0.1%2026-Q2
National Philanthropic Trust new24,723$105K0.1%2026-Q2
Forefront Analytics, LLC added21,822$93K0.1%2026-Q2
STIFEL FINANCIAL CORP added20,479$87K0.1%2026-Q2
State of New Jersey Common Pension Fund D20,105$85K0.0%2026-Q2
Vontobel Holding Ltd.20,000$85K0.0%2026-Q2
Aigen Investment Management, LP new19,319$82K0.0%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC trimmed19,035$81K0.0%2026-Q2
RHUMBLINE ADVISERS added15,967$68K0.0%2026-Q2
UBS Group AG trimmed15,459$66K0.0%2026-Q2
PORTLAND INVESTMENT COUNSEL INC.15,000$64K0.0%2026-Q2
Federation des caisses Desjardins du Quebec14,302$61K0.0%2026-Q2
Erste Asset Management GmbH14,000$58K0.0%2026-Q2
Cerity Partners LLC13,570$58K0.0%2026-Q2
Schonfeld Strategic Advisors LLC trimmed13,399$57K0.0%2026-Q2
Walleye Capital LLC trimmed13,000$55K0.0%2026-Q2
JPMORGAN CHASE & CO added13,056$54K0.0%2026-Q2
HORIZON KINETICS ASSET MANAGEMENT LLC trimmed12,584$53K0.0%2026-Q2
Aquatic Capital Management LLC trimmed12,343$52K0.0%2026-Q2
Jain Global LLC new12,000$51K0.0%2026-Q2
Crossmark Global Holdings, Inc. trimmed11,402$48K0.0%2026-Q2
Pinnacle Wealth Management Advisory Group, LLC10,985$47K0.0%2026-Q2
State of Wyoming new10,760$46K0.0%2026-Q2
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS10,116$43K0.0%2026-Q2
GAMMA Investing LLC added7,704$33K0.0%2026-Q2
China Universal Asset Management Co., Ltd. trimmed7,420$31K0.0%2026-Q2
NATIXIS4,645$20K0.0%2026-Q2
Tower Research Capital LLC (TRC) added3,669$16K0.0%2026-Q2
BARCLAYS PLC added3,149$13K0.0%2026-Q2
ROYAL BANK OF CANADA trimmed2,500$11K0.0%2026-Q2
Mirae Asset Global Investments Co., Ltd. trimmed2,085$9K0.0%2026-Q2
GROUP ONE TRADING LLC added1,938$8K0.0%2026-Q2
ASSETMARK, INC trimmed1,588$7K0.0%2026-Q2
CITIGROUP INC trimmed1,175$5K0.0%2026-Q2
BNP PARIBAS FINANCIAL MARKETS1,016$4K0.0%2026-Q2
GF FUND MANAGEMENT CO. LTD. trimmed962$4K0.0%2026-Q2
JONES FINANCIAL COMPANIES LLLP added700$3K0.0%2026-Q2
Quarry LP new537$2K0.0%2026-Q2
HighMark Wealth Management LLC435$2K0.0%2026-Q2
Arax Advisory Partners added304$1K0.0%2026-Q2
WELLS FARGO & COMPANY/MN200$8480.0%2026-Q2
Winch Advisory Services, LLC172$7290.0%2026-Q2
EverSource Wealth Advisors, LLC added147$6230.0%2026-Q2
Caitong International Asset Management Co., Ltd added117$4960.0%2026-Q2
OSAIC HOLDINGS, INC.10$420.0%2026-Q2
FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.9$380.0%2026-Q2
SBI Securities Co., Ltd.6$250.0%2026-Q2
Caitlin John, LLC2$80.0%2026-Q2
WESTFIELD CAPITAL MANAGEMENT CO LP added3,016,026$21M12.5%2025-Q4 stale (2 quarters behind)

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership