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Institutional Ownership · SEC Form 13F

Who owns BCYC (BCYC)


Which tracked institutional funds hold BCYC, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See BCYC company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

97
Institutional holders
37,453,636
Shares held (tracked funds)
54.0%
Of shares outstanding

How the tape is positioned

The tracked-fund tape on BCYC is one-sided between 2025-Q4 and 2026-Q1: 9 added or opened and 34 trimmed or exited — on balance reducing.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

BCYC’s largest tracked holder by dollar value, BAKER BROS. ADVISORS LP, sizes it at 0.3% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.3pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in BCYC divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 97 tracked filers holding BCYC, 58 increased or opened the position and 42 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in BCYC between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 4

  • DIADEMA PARTNERS LP$2M
  • Qube Research & Technologies Ltd$1M
  • Persistent Asset Partners Ltd$559K
  • Peapod Lane Capital LLC$550K

Full exits 9

  • WESTFIELD CAPITAL MANAGEMENT CO LP$21M
  • Candriam S.C.A.$8M
  • BNP PARIBAS ASSET MANAGEMENT Holding S.A.$4M
  • Jefferies Financial Group Inc.$2M
  • TWO SIGMA ADVISERS, LP$1M
  • DekaBank Deutsche Girozentrale$801K

Largest adds

  • Long Focus Capital Management, LLC$4M
  • MARSHALL WACE, LLP$1M
  • JANE STREET GROUP, LLC$565K
  • RENAISSANCE TECHNOLOGIES LLC$532K
  • GOLDMAN SACHS GROUP INC$336K

Largest trims

  • BAKER BROS. ADVISORS LP$27M
  • FCPM III SERVICES B.V.$8M
  • ARMISTICE CAPITAL, LLC$7M
  • Siren, L.L.C.$7M
  • GSK plc$4M
  • PRICE T ROWE ASSOCIATES INC /MD/$4M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
BAKER BROS. ADVISORS LP10,885,357$51M19.5%2026-Q1
FCPM III SERVICES B.V.3,468,430$16M6.2%2026-Q1
ARMISTICE CAPITAL, LLC added3,398,000$16M6.1%2026-Q1
Long Focus Capital Management, LLC added3,310,687$15M5.9%2026-Q1
ACADIAN ASSET MANAGEMENT LLC added1,968,025$9M3.5%2026-Q1
Siren, L.L.C. trimmed1,560,882$7M2.8%2026-Q1
GSK plc1,529,561$7M2.7%2026-Q1
PRINCIPAL FINANCIAL GROUP INC added1,174,625$5M2.1%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ trimmed1,028,243$5M1.8%2026-Q1
RENAISSANCE TECHNOLOGIES LLC added979,300$5M1.8%2026-Q1
MORGAN STANLEY added618,327$3M1.1%2026-Q1
SCHRODER INVESTMENT MANAGEMENT GROUP added615,833$3M1.0%2026-Q1
DIADEMA PARTNERS LP new476,424$2M0.9%2026-Q1
Birchview Capital, LP added463,599$2M0.8%2026-Q1
SILVERCREST ASSET MANAGEMENT GROUP LLC trimmed428,684$2M0.8%2026-Q1
CITADEL ADVISORS LLC added377,085$2M0.7%2026-Q1
MARSHALL WACE, LLP added371,307$2M0.7%2026-Q1
Qube Research & Technologies Ltd added308,617$1M0.6%2026-Q1
MILLENNIUM MANAGEMENT LLC trimmed283,986$1M0.5%2026-Q1
BlackRock, Inc. trimmed278,992$1M0.5%2026-Q1
MOORE CAPITAL MANAGEMENT, LP275,000$1M0.5%2026-Q1
Rangeley Capital, LLC added232,260$1M0.4%2026-Q1
JANE STREET GROUP, LLC added218,115$1M0.4%2026-Q1
Palo Alto Investors LP trimmed201,890$937K0.4%2026-Q1
Eversept Partners, LP added190,715$885K0.3%2026-Q1
PINNACLE ASSOCIATES LTD trimmed185,410$860K0.3%2026-Q1
PLATINUM INVESTMENT MANAGEMENT LTD184,603$857K0.3%2026-Q1
FLAX POND CAPITAL, LLC added176,136$817K0.3%2026-Q1
TWO SIGMA INVESTMENTS, LP added164,800$765K0.3%2026-Q1
Point72 Asset Management, L.P. added130,422$605K0.2%2026-Q1
MANUFACTURERS LIFE INSURANCE COMPANY, THE127,863$593K0.2%2026-Q1
Persistent Asset Partners Ltd new120,437$559K0.2%2026-Q1
Peapod Lane Capital LLC new121,106$550K0.2%2026-Q1
Marex Group plc added115,000$534K0.2%2026-Q1
GOLDMAN SACHS GROUP INC added110,147$511K0.2%2026-Q1
XTX Topco Ltd added106,392$494K0.2%2026-Q1
TD Asset Management Inc trimmed91,992$427K0.2%2026-Q1
ADAR1 Capital Management, LLC added71,298$331K0.1%2026-Q1
DAFNA Capital Management LLC64,492$299K0.1%2026-Q1
EntryPoint Capital, LLC added63,906$297K0.1%2026-Q1
Man Group plc added63,305$294K0.1%2026-Q1
AXQ CAPITAL, LP new63,134$293K0.1%2026-Q1
State of Tennessee, Department of Treasury61,153$284K0.1%2026-Q1
SEI INVESTMENTS CO added52,784$245K0.1%2026-Q1
Jump Financial, LLC added52,544$244K0.1%2026-Q1
HRT FINANCIAL LP added45,915$213K0.1%2026-Q1
ALPS ADVISORS INC trimmed40,651$189K0.1%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed37,888$176K0.1%2026-Q1
Virtus Investment Advisers, LLC added36,601$170K0.1%2026-Q1
Engineers Gate Manager LP added35,400$164K0.1%2026-Q1
UBS Group AG added32,159$149K0.1%2026-Q1
STATE STREET CORP trimmed30,512$142K0.1%2026-Q1
WOODSTOCK CORP29,146$135K0.1%2026-Q1
GSA CAPITAL PARTNERS LLP added26,842$125K0.0%2026-Q1
Aquatic Capital Management LLC added26,160$121K0.0%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC25,129$117K0.0%2026-Q1
R Squared Ltd added21,057$98K0.0%2026-Q1
State of New Jersey Common Pension Fund D20,105$93K0.0%2026-Q1
Vontobel Holding Ltd. added20,000$93K0.0%2026-Q1
WESTFIELD CAPITAL MANAGEMENT CO LP added3,016,026$21M8.3%2025-Q4 stale
RA CAPITAL MANAGEMENT, L.P.1,093,477$9M3.6%2025-Q1 stale
Candriam S.C.A. added1,192,279$8M3.3%2025-Q4 stale
Deep Track Capital, LP added1,203,244$8M3.2%2025-Q2 stale
EcoR1 Capital, LLC910,000$8M3.0%2025-Q1 stale
TYBOURNE CAPITAL MANAGEMENT (HK) LTD added993,743$7M2.7%2025-Q2 stale
BNP PARIBAS ASSET MANAGEMENT Holding S.A. trimmed568,225$4M1.6%2025-Q4 stale
Woodline Partners LP trimmed362,325$3M1.0%2025-Q2 stale
Jefferies Financial Group Inc. trimmed297,247$2M0.8%2025-Q4 stale
AXA S.A. trimmed280,152$2M0.8%2025-Q2 stale
Aquilo Capital Management, LLC trimmed171,695$1M0.6%2025-Q1 stale
Handelsbanken Fonder AB trimmed150,000$1M0.4%2025-Q3 stale
TWO SIGMA ADVISERS, LP trimmed146,100$1M0.4%2025-Q4 stale
DekaBank Deutsche Girozentrale30,000$801K0.3%2025-Q4 stale
Cubist Systematic Strategies, LLC added103,410$800K0.3%2025-Q3 stale
Walleye Capital LLC added111,659$791K0.3%2025-Q4 stale
Janney Montgomery Scott LLC new100,291$697K0.3%2025-Q2 stale
Soleus Capital Management, L.P. added100,000$695K0.3%2025-Q2 stale
Caption Management, LLC trimmed81,559$692K0.3%2025-Q1 stale
BANK OF AMERICA CORP /DE/ trimmed96,401$683K0.3%2025-Q4 stale
MONIMUS CAPITAL MANAGEMENT, LP added93,840$664K0.3%2025-Q4 stale
Shay Capital LLC new60,000$509K0.2%2025-Q1 stale
Nan Fung Group Holdings Ltd68,943$488K0.2%2025-Q4 stale
Quadrature Capital Ltd added46,728$331K0.1%2025-Q4 stale
Skandinaviska Enskilda Banken AB (publ)42,729$297K0.1%2025-Q2 stale
HARBOR CAPITAL ADVISORS, INC. trimmed40,486$287K0.1%2025-Q4 stale
Paloma Partners Management Co new39,250$273K0.1%2025-Q2 stale
Dynamic Technology Lab Private Ltd trimmed27,959$216K0.1%2025-Q3 stale
UBS AM, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS LLC added27,300$190K0.1%2025-Q2 stale
D. E. Shaw & Co., Inc. new21,548$153K0.1%2025-Q4 stale
SIMPLEX TRADING, LLC added19,986$142K0.1%2025-Q4 stale
FOX RUN MANAGEMENT, L.L.C. new19,771$140K0.1%2025-Q4 stale
AMERIPRISE FINANCIAL INC added14,972$116K0.0%2025-Q3 stale
EXCHANGE TRADED CONCEPTS, LLC added12,764$108K0.0%2025-Q1 stale
ENVESTNET ASSET MANAGEMENT INC trimmed12,420$105K0.0%2025-Q1 stale
Squarepoint Ops LLC added13,259$103K0.0%2025-Q3 stale
PNC Financial Services Group, Inc. added14,138$100K0.0%2025-Q4 stale
Graham Capital Management, L.P. trimmed12,375$96K0.0%2025-Q3 stale
Vanguard Personalized Indexing Management, LLC trimmed12,776$90K0.0%2025-Q4 stale
TOCQUEVILLE ASSET MANAGEMENT L.P. added12,600$89K0.0%2025-Q4 stale
RAYMOND JAMES FINANCIAL INC added12,336$87K0.0%2025-Q4 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership