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Institutional Ownership · SEC Form 13F

Who owns BioCryst Pharmaceuticals, Inc. (BCRX)


Which tracked institutional funds hold BCRX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See BCRX company fundamentals →

Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

300
Institutional holders
248M
Shares held (tracked funds)

How the tape is positioned

115 tracked funds added or opened BCRX while 47 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

BCRX’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes BCRX more heavily than its largest holder by dollar value does.

Book-share is each fund’s reported value in BCRX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 300 tracked filers holding BCRX, 188 increased or opened the position and 123 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in BCRX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 30

  • VANGUARD PORTFOLIO MANAGEMENT LLC$107M
  • VANGUARD CAPITAL MANAGEMENT LLC$106M
  • TCG Crossover Management, LLC$105M
  • Frazier Life Sciences Management, L.P.$38M
  • RFG Advisory, LLC$27M
  • Candriam S.C.A.$22M

Full exits 23

  • VANGUARD GROUP INC$160M
  • TWO SIGMA ADVISERS, LP$32M
  • BAKER BROS. ADVISORS LP$22M
  • Qube Research & Technologies Ltd$17M
  • Point72 Asset Management, L.P.$9M
  • TANG CAPITAL MANAGEMENT LLC$6M

Largest adds

  • BlackRock, Inc.$51M
  • Vestal Point Capital, LP$49M
  • PERCEPTIVE ADVISORS LLC$46M
  • Aberdeen Group plc$41M
  • BANK OF AMERICA CORP /DE/$36M
  • DEERFIELD MANAGEMENT COMPANY, L.P.$31M

Largest trims

  • Kynam Capital Management, LP$19M
  • Squarepoint Ops LLC$13M
  • RENAISSANCE TECHNOLOGIES LLC$9M
  • BNP PARIBAS FINANCIAL MARKETS$7M
  • Elmind Capital, LP$7M
  • D. E. Shaw & Co., Inc.$7M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
BlackRock, Inc. added22,650,988$216M8.0%2026-Q1
RA CAPITAL MANAGEMENT, L.P.15,827,186$151M5.6%2026-Q1
DEERFIELD MANAGEMENT COMPANY, L.P. added15,038,000$143M5.3%2026-Q1
STATE STREET CORP added12,208,360$116M4.3%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new11,244,625$107M4.0%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new11,135,762$106M4.0%2026-Q1
TCG Crossover Management, LLC new11,020,968$105M3.9%2026-Q1
JANUS HENDERSON GROUP PLC added8,908,506$85M3.2%2026-Q1
PERCEPTIVE ADVISORS LLC added7,434,033$71M2.6%2026-Q1
Vestal Point Capital, LP added7,025,000$67M2.5%2026-Q1
TWO SIGMA INVESTMENTS, LP added6,392,628$61M2.3%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added5,782,776$55M2.1%2026-Q1
Kynam Capital Management, LP trimmed5,680,795$54M2.0%2026-Q1
BANK OF AMERICA CORP /DE/ added5,091,765$48M1.8%2026-Q1
Aberdeen Group plc added5,040,670$48M1.8%2026-Q1
UBS Group AG trimmed4,943,994$47M1.8%2026-Q1
Frazier Life Sciences Management, L.P. new4,009,240$38M1.4%2026-Q1
Royalty Pharma Sub-Manager, LLC3,846,154$37M1.4%2026-Q1
Nuveen, LLC added3,819,263$36M1.4%2026-Q1
GW&K Investment Management, LLC added3,240,462$31M1.2%2026-Q1
Eversept Partners, LP added3,039,820$29M1.1%2026-Q1
RFG Advisory, LLC new2,870,700$27M1.0%2026-Q1
SUSQUEHANNA INTERNATIONAL GROUP, LLP added2,815,304$27M1.0%2026-Q1
Fisher Asset Management, LLC added2,733,253$26M1.0%2026-Q1
DIMENSIONAL FUND ADVISORS LP added2,690,651$26M1.0%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added2,350,405$22M0.8%2026-Q1
GOLDMAN SACHS GROUP INC trimmed2,347,443$22M0.8%2026-Q1
Candriam S.C.A. new2,286,841$22M0.8%2026-Q1
RICE HALL JAMES & ASSOCIATES, LLC added2,230,105$21M0.8%2026-Q1
NORTHERN TRUST CORP added2,104,725$20M0.7%2026-Q1
MORGAN STANLEY added2,022,988$19M0.7%2026-Q1
Nantahala Capital Management, LLC added1,987,397$19M0.7%2026-Q1
STIFEL FINANCIAL CORP added1,825,184$17M0.6%2026-Q1
Parkman Healthcare Partners LLC added1,708,099$16M0.6%2026-Q1
VANGUARD FIDUCIARY TRUST CO new1,664,297$16M0.6%2026-Q1
JPMORGAN CHASE & CO added1,541,978$15M0.5%2026-Q1
OP Asset Management Ltd added1,252,863$14M0.5%2026-Q1
ORBIMED ADVISORS LLC trimmed1,425,200$14M0.5%2026-Q1
Legal & General Group Plc added1,411,199$13M0.5%2026-Q1
Schonfeld Strategic Advisors LLC added1,337,693$13M0.5%2026-Q1
BNP PARIBAS FINANCIAL MARKETS trimmed1,302,257$12M0.5%2026-Q1
Man Group plc added1,293,300$12M0.5%2026-Q1
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND added1,227,040$12M0.4%2026-Q1
JUPITER ASSET MANAGEMENT LTD trimmed1,196,371$11M0.4%2026-Q1
Invesco Ltd. trimmed1,161,849$11M0.4%2026-Q1
CITADEL ADVISORS LLC trimmed1,018,743$10M0.4%2026-Q1
JACOBS LEVY EQUITY MANAGEMENT, INC trimmed1,004,373$10M0.4%2026-Q1
Elmind Capital, LP trimmed1,000,000$10M0.4%2026-Q1
Rosalind Advisors, Inc. new923,057$9M0.3%2026-Q1
SPHERA FUNDS MANAGEMENT LTD. added866,464$8M0.3%2026-Q1
DEUTSCHE BANK AG\ added821,367$8M0.3%2026-Q1
FIRST TRUST ADVISORS LP added800,900$8M0.3%2026-Q1
RENAISSANCE TECHNOLOGIES LLC trimmed776,990$7M0.3%2026-Q1
Hillsdale Investment Management Inc. added639,100$6M0.2%2026-Q1
Bridgewater Associates, LP added638,054$6M0.2%2026-Q1
Bank of New York Mellon Corp added637,658$6M0.2%2026-Q1
FMR LLC added633,132$6M0.2%2026-Q1
IMC-Chicago, LLC new631,290$6M0.2%2026-Q1
JANE STREET GROUP, LLC trimmed622,607$6M0.2%2026-Q1
PDT Partners, LLC trimmed563,440$5M0.2%2026-Q1
VOYA INVESTMENT MANAGEMENT LLC trimmed536,304$5M0.2%2026-Q1
FRANKLIN RESOURCES INC trimmed523,281$5M0.2%2026-Q1
Hudson Bay Capital Management LP trimmed490,369$5M0.2%2026-Q1
Pictet Asset Management Holding SA trimmed471,573$4M0.2%2026-Q1
AQR CAPITAL MANAGEMENT LLC trimmed438,439$4M0.2%2026-Q1
PRINCIPAL FINANCIAL GROUP INC added430,558$4M0.2%2026-Q1
DAFNA Capital Management LLC added430,248$4M0.2%2026-Q1
Swiss National Bank added408,668$4M0.1%2026-Q1
DOLIVER ADVISORS, LP added374,328$4M0.1%2026-Q1
Susquehanna Portfolio Strategies, LLC trimmed374,016$4M0.1%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed368,978$4M0.1%2026-Q1
Rafferty Asset Management, LLC trimmed354,260$3M0.1%2026-Q1
Gotham Asset Management, LLC added312,961$3M0.1%2026-Q1
FEDERATED HERMES, INC. added306,464$3M0.1%2026-Q1
D. E. Shaw & Co., Inc. trimmed302,101$3M0.1%2026-Q1
VANGUARD GROUP INC trimmed20,531,623$160M6.0%2025-Q4 stale
ALKEON CAPITAL MANAGEMENT LLC trimmed5,464,021$41M1.5%2025-Q3 stale
TWO SIGMA ADVISERS, LP trimmed4,089,112$32M1.2%2025-Q4 stale
RP Management, LLC3,846,154$29M1.1%2025-Q1 stale
Hood River Capital Management LLC added3,620,261$27M1.0%2025-Q3 stale
BAKER BROS. ADVISORS LP added2,822,727$22M0.8%2025-Q4 stale
Qube Research & Technologies Ltd trimmed2,164,162$17M0.6%2025-Q4 stale
Avoro Capital Advisors LLC trimmed1,250,000$9M0.4%2025-Q3 stale
Point72 Asset Management, L.P. added1,213,576$9M0.4%2025-Q4 stale
Cubist Systematic Strategies, LLC added1,246,696$9M0.4%2025-Q3 stale
M&G PLC new1,046,016$9M0.4%2025-Q2 stale
SEGALL BRYANT & HAMILL, LLC trimmed1,134,813$9M0.3%2025-Q3 stale
Driehaus Capital Management LLC new766,899$7M0.3%2025-Q2 stale
TANG CAPITAL MANAGEMENT LLC800,000$6M0.2%2025-Q4 stale
Caligan Partners LP trimmed638,908$6M0.2%2025-Q2 stale
HRT FINANCIAL LP added716,826$6M0.2%2025-Q4 stale
ALGERT GLOBAL LLC trimmed713,088$5M0.2%2025-Q3 stale
Trexquant Investment LP added559,184$5M0.2%2025-Q2 stale
LORD, ABBETT & CO. LLC new532,350$5M0.2%2025-Q2 stale
SCHRODER INVESTMENT MANAGEMENT GROUP added535,968$4M0.2%2025-Q3 stale
Kodai Capital Management LP new468,799$4M0.1%2025-Q1 stale
VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed449,743$4M0.1%2025-Q4 stale
Y-Intercept (Hong Kong) Ltd added434,531$3M0.1%2025-Q3 stale
Informed Momentum Co LLC added334,347$3M0.1%2025-Q2 stale
Connor, Clark & Lunn Investment Management Ltd. trimmed357,086$3M0.1%2025-Q4 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership