Who owns BioCryst Pharmaceuticals, Inc. (BCRX)
Which tracked institutional funds hold BCRX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See BCRX company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
115 tracked funds added or opened BCRX while 47 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
BCRX’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes BCRX more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in BCRX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 300 tracked filers holding BCRX, 188 increased or opened the position and 123 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in BCRX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 30
- VANGUARD PORTFOLIO MANAGEMENT LLC$107M
- VANGUARD CAPITAL MANAGEMENT LLC$106M
- TCG Crossover Management, LLC$105M
- Frazier Life Sciences Management, L.P.$38M
- RFG Advisory, LLC$27M
- Candriam S.C.A.$22M
Full exits 23
- VANGUARD GROUP INC$160M
- TWO SIGMA ADVISERS, LP$32M
- BAKER BROS. ADVISORS LP$22M
- Qube Research & Technologies Ltd$17M
- Point72 Asset Management, L.P.$9M
- TANG CAPITAL MANAGEMENT LLC$6M
Largest adds
- BlackRock, Inc.$51M
- Vestal Point Capital, LP$49M
- PERCEPTIVE ADVISORS LLC$46M
- Aberdeen Group plc$41M
- BANK OF AMERICA CORP /DE/$36M
- DEERFIELD MANAGEMENT COMPANY, L.P.$31M
Largest trims
- Kynam Capital Management, LP$19M
- Squarepoint Ops LLC$13M
- RENAISSANCE TECHNOLOGIES LLC$9M
- BNP PARIBAS FINANCIAL MARKETS$7M
- Elmind Capital, LP$7M
- D. E. Shaw & Co., Inc.$7M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| BlackRock, Inc. added | 22,650,988 | $216M | 8.0% | 2026-Q1 |
| RA CAPITAL MANAGEMENT, L.P. | 15,827,186 | $151M | 5.6% | 2026-Q1 |
| DEERFIELD MANAGEMENT COMPANY, L.P. added | 15,038,000 | $143M | 5.3% | 2026-Q1 |
| STATE STREET CORP added | 12,208,360 | $116M | 4.3% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 11,244,625 | $107M | 4.0% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 11,135,762 | $106M | 4.0% | 2026-Q1 |
| TCG Crossover Management, LLC new | 11,020,968 | $105M | 3.9% | 2026-Q1 |
| JANUS HENDERSON GROUP PLC added | 8,908,506 | $85M | 3.2% | 2026-Q1 |
| PERCEPTIVE ADVISORS LLC added | 7,434,033 | $71M | 2.6% | 2026-Q1 |
| Vestal Point Capital, LP added | 7,025,000 | $67M | 2.5% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP added | 6,392,628 | $61M | 2.3% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 5,782,776 | $55M | 2.1% | 2026-Q1 |
| Kynam Capital Management, LP trimmed | 5,680,795 | $54M | 2.0% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 5,091,765 | $48M | 1.8% | 2026-Q1 |
| Aberdeen Group plc added | 5,040,670 | $48M | 1.8% | 2026-Q1 |
| UBS Group AG trimmed | 4,943,994 | $47M | 1.8% | 2026-Q1 |
| Frazier Life Sciences Management, L.P. new | 4,009,240 | $38M | 1.4% | 2026-Q1 |
| Royalty Pharma Sub-Manager, LLC | 3,846,154 | $37M | 1.4% | 2026-Q1 |
| Nuveen, LLC added | 3,819,263 | $36M | 1.4% | 2026-Q1 |
| GW&K Investment Management, LLC added | 3,240,462 | $31M | 1.2% | 2026-Q1 |
| Eversept Partners, LP added | 3,039,820 | $29M | 1.1% | 2026-Q1 |
| RFG Advisory, LLC new | 2,870,700 | $27M | 1.0% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 2,815,304 | $27M | 1.0% | 2026-Q1 |
| Fisher Asset Management, LLC added | 2,733,253 | $26M | 1.0% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 2,690,651 | $26M | 1.0% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 2,350,405 | $22M | 0.8% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC trimmed | 2,347,443 | $22M | 0.8% | 2026-Q1 |
| Candriam S.C.A. new | 2,286,841 | $22M | 0.8% | 2026-Q1 |
| RICE HALL JAMES & ASSOCIATES, LLC added | 2,230,105 | $21M | 0.8% | 2026-Q1 |
| NORTHERN TRUST CORP added | 2,104,725 | $20M | 0.7% | 2026-Q1 |
| MORGAN STANLEY added | 2,022,988 | $19M | 0.7% | 2026-Q1 |
| Nantahala Capital Management, LLC added | 1,987,397 | $19M | 0.7% | 2026-Q1 |
| STIFEL FINANCIAL CORP added | 1,825,184 | $17M | 0.6% | 2026-Q1 |
| Parkman Healthcare Partners LLC added | 1,708,099 | $16M | 0.6% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 1,664,297 | $16M | 0.6% | 2026-Q1 |
| JPMORGAN CHASE & CO added | 1,541,978 | $15M | 0.5% | 2026-Q1 |
| OP Asset Management Ltd added | 1,252,863 | $14M | 0.5% | 2026-Q1 |
| ORBIMED ADVISORS LLC trimmed | 1,425,200 | $14M | 0.5% | 2026-Q1 |
| Legal & General Group Plc added | 1,411,199 | $13M | 0.5% | 2026-Q1 |
| Schonfeld Strategic Advisors LLC added | 1,337,693 | $13M | 0.5% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS trimmed | 1,302,257 | $12M | 0.5% | 2026-Q1 |
| Man Group plc added | 1,293,300 | $12M | 0.5% | 2026-Q1 |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND added | 1,227,040 | $12M | 0.4% | 2026-Q1 |
| JUPITER ASSET MANAGEMENT LTD trimmed | 1,196,371 | $11M | 0.4% | 2026-Q1 |
| Invesco Ltd. trimmed | 1,161,849 | $11M | 0.4% | 2026-Q1 |
| CITADEL ADVISORS LLC trimmed | 1,018,743 | $10M | 0.4% | 2026-Q1 |
| JACOBS LEVY EQUITY MANAGEMENT, INC trimmed | 1,004,373 | $10M | 0.4% | 2026-Q1 |
| Elmind Capital, LP trimmed | 1,000,000 | $10M | 0.4% | 2026-Q1 |
| Rosalind Advisors, Inc. new | 923,057 | $9M | 0.3% | 2026-Q1 |
| SPHERA FUNDS MANAGEMENT LTD. added | 866,464 | $8M | 0.3% | 2026-Q1 |
| DEUTSCHE BANK AG\ added | 821,367 | $8M | 0.3% | 2026-Q1 |
| FIRST TRUST ADVISORS LP added | 800,900 | $8M | 0.3% | 2026-Q1 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 776,990 | $7M | 0.3% | 2026-Q1 |
| Hillsdale Investment Management Inc. added | 639,100 | $6M | 0.2% | 2026-Q1 |
| Bridgewater Associates, LP added | 638,054 | $6M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp added | 637,658 | $6M | 0.2% | 2026-Q1 |
| FMR LLC added | 633,132 | $6M | 0.2% | 2026-Q1 |
| IMC-Chicago, LLC new | 631,290 | $6M | 0.2% | 2026-Q1 |
| JANE STREET GROUP, LLC trimmed | 622,607 | $6M | 0.2% | 2026-Q1 |
| PDT Partners, LLC trimmed | 563,440 | $5M | 0.2% | 2026-Q1 |
| VOYA INVESTMENT MANAGEMENT LLC trimmed | 536,304 | $5M | 0.2% | 2026-Q1 |
| FRANKLIN RESOURCES INC trimmed | 523,281 | $5M | 0.2% | 2026-Q1 |
| Hudson Bay Capital Management LP trimmed | 490,369 | $5M | 0.2% | 2026-Q1 |
| Pictet Asset Management Holding SA trimmed | 471,573 | $4M | 0.2% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 438,439 | $4M | 0.2% | 2026-Q1 |
| PRINCIPAL FINANCIAL GROUP INC added | 430,558 | $4M | 0.2% | 2026-Q1 |
| DAFNA Capital Management LLC added | 430,248 | $4M | 0.2% | 2026-Q1 |
| Swiss National Bank added | 408,668 | $4M | 0.1% | 2026-Q1 |
| DOLIVER ADVISORS, LP added | 374,328 | $4M | 0.1% | 2026-Q1 |
| Susquehanna Portfolio Strategies, LLC trimmed | 374,016 | $4M | 0.1% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 368,978 | $4M | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC trimmed | 354,260 | $3M | 0.1% | 2026-Q1 |
| Gotham Asset Management, LLC added | 312,961 | $3M | 0.1% | 2026-Q1 |
| FEDERATED HERMES, INC. added | 306,464 | $3M | 0.1% | 2026-Q1 |
| D. E. Shaw & Co., Inc. trimmed | 302,101 | $3M | 0.1% | 2026-Q1 |
| VANGUARD GROUP INC trimmed | 20,531,623 | $160M | 6.0% | 2025-Q4 stale |
| ALKEON CAPITAL MANAGEMENT LLC trimmed | 5,464,021 | $41M | 1.5% | 2025-Q3 stale |
| TWO SIGMA ADVISERS, LP trimmed | 4,089,112 | $32M | 1.2% | 2025-Q4 stale |
| RP Management, LLC | 3,846,154 | $29M | 1.1% | 2025-Q1 stale |
| Hood River Capital Management LLC added | 3,620,261 | $27M | 1.0% | 2025-Q3 stale |
| BAKER BROS. ADVISORS LP added | 2,822,727 | $22M | 0.8% | 2025-Q4 stale |
| Qube Research & Technologies Ltd trimmed | 2,164,162 | $17M | 0.6% | 2025-Q4 stale |
| Avoro Capital Advisors LLC trimmed | 1,250,000 | $9M | 0.4% | 2025-Q3 stale |
| Point72 Asset Management, L.P. added | 1,213,576 | $9M | 0.4% | 2025-Q4 stale |
| Cubist Systematic Strategies, LLC added | 1,246,696 | $9M | 0.4% | 2025-Q3 stale |
| M&G PLC new | 1,046,016 | $9M | 0.4% | 2025-Q2 stale |
| SEGALL BRYANT & HAMILL, LLC trimmed | 1,134,813 | $9M | 0.3% | 2025-Q3 stale |
| Driehaus Capital Management LLC new | 766,899 | $7M | 0.3% | 2025-Q2 stale |
| TANG CAPITAL MANAGEMENT LLC | 800,000 | $6M | 0.2% | 2025-Q4 stale |
| Caligan Partners LP trimmed | 638,908 | $6M | 0.2% | 2025-Q2 stale |
| HRT FINANCIAL LP added | 716,826 | $6M | 0.2% | 2025-Q4 stale |
| ALGERT GLOBAL LLC trimmed | 713,088 | $5M | 0.2% | 2025-Q3 stale |
| Trexquant Investment LP added | 559,184 | $5M | 0.2% | 2025-Q2 stale |
| LORD, ABBETT & CO. LLC new | 532,350 | $5M | 0.2% | 2025-Q2 stale |
| SCHRODER INVESTMENT MANAGEMENT GROUP added | 535,968 | $4M | 0.2% | 2025-Q3 stale |
| Kodai Capital Management LP new | 468,799 | $4M | 0.1% | 2025-Q1 stale |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 449,743 | $4M | 0.1% | 2025-Q4 stale |
| Y-Intercept (Hong Kong) Ltd added | 434,531 | $3M | 0.1% | 2025-Q3 stale |
| Informed Momentum Co LLC added | 334,347 | $3M | 0.1% | 2025-Q2 stale |
| Connor, Clark & Lunn Investment Management Ltd. trimmed | 357,086 | $3M | 0.1% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.