Who owns APLS (APLS)
Which tracked institutional funds hold APLS, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See APLS company fundamentals →
Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
183 tracked funds added or opened APLS while 67 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
APLS’s largest tracked holder by dollar value, Avoro Capital Advisors LLC, sizes it at 4.8% of its own reported 13F book, while the median holder sizes it at 0.1% of theirs — a 4.8pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in APLS divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 322 tracked filers holding APLS, 215 increased or opened the position and 155 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in APLS between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 88
- VANGUARD PORTFOLIO MANAGEMENT LLC$217M
- Pentwater Capital Management LP$211M
- VANGUARD CAPITAL MANAGEMENT LLC$192M
- HBK INVESTMENTS L P$143M
- GLAZER CAPITAL, LLC$52M
- TIG Advisors, LLC$50M
Full exits 37
- VANGUARD GROUP INC$249M
- Polar Capital Holdings Plc$93M
- Siren, L.L.C.$65M
- ORBIMED ADVISORS LLC$61M
- JENNISON ASSOCIATES LLC$38M
- BANK OF NOVA SCOTIA$27M
Largest adds
- BlackRock, Inc.$240M
- Avoro Capital Advisors LLC$185M
- MORGAN STANLEY$174M
- STATE STREET CORP$159M
- Point72 Asset Management, L.P.$153M
- UBS Group AG$145M
Largest trims
- WELLINGTON MANAGEMENT GROUP LLP$310M
- RTW INVESTMENTS, LP$44M
- AQR CAPITAL MANAGEMENT LLC$40M
- DEUTSCHE BANK AG\$31M
- LOS ANGELES CAPITAL MANAGEMENT LLC$16M
- M&T Bank Corp$15M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | 12,222,222 | $492M | 8.4% | 2026-Q1 |
| MORGAN STANLEY added | 10,042,399 | $404M | 6.9% | 2026-Q1 |
| BlackRock, Inc. added | 9,881,191 | $398M | 6.8% | 2026-Q1 |
| STATE STREET CORP added | 6,844,990 | $275M | 4.7% | 2026-Q1 |
| UBS Group AG added | 6,206,681 | $250M | 4.3% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 5,404,559 | $217M | 3.7% | 2026-Q1 |
| Pentwater Capital Management LP new | 5,250,000 | $211M | 3.6% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 4,768,944 | $192M | 3.3% | 2026-Q1 |
| Deep Track Capital, LP trimmed | 4,532,374 | $182M | 3.1% | 2026-Q1 |
| Point72 Asset Management, L.P. added | 4,183,918 | $168M | 2.9% | 2026-Q1 |
| RTW INVESTMENTS, LP trimmed | 3,685,045 | $148M | 2.5% | 2026-Q1 |
| HBK INVESTMENTS L P new | 3,550,000 | $143M | 2.4% | 2026-Q1 |
| SUVRETTA CAPITAL MANAGEMENT, LLC trimmed | 3,518,471 | $142M | 2.4% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC added | 2,256,802 | $91M | 1.5% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 2,075,075 | $84M | 1.4% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 1,980,144 | $80M | 1.4% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. added | 1,917,501 | $77M | 1.3% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 1,338,995 | $54M | 0.9% | 2026-Q1 |
| GLAZER CAPITAL, LLC new | 1,294,196 | $52M | 0.9% | 2026-Q1 |
| TIG Advisors, LLC added | 1,252,986 | $50M | 0.9% | 2026-Q1 |
| TORONTO DOMINION BANK added | 1,236,436 | $50M | 0.8% | 2026-Q1 |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND added | 1,202,100 | $48M | 0.8% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 1,190,864 | $48M | 0.8% | 2026-Q1 |
| Hudson Bay Capital Management LP added | 1,190,416 | $48M | 0.8% | 2026-Q1 |
| FIL Ltd added | 1,140,000 | $46M | 0.8% | 2026-Q1 |
| Kryger Capital LLC new | 1,100,000 | $44M | 0.8% | 2026-Q1 |
| SOROS FUND MANAGEMENT LLC added | 1,056,000 | $42M | 0.7% | 2026-Q1 |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC new | 1,013,500 | $41M | 0.7% | 2026-Q1 |
| Woodline Partners LP added | 976,175 | $39M | 0.7% | 2026-Q1 |
| RENAISSANCE TECHNOLOGIES LLC added | 935,958 | $38M | 0.6% | 2026-Q1 |
| MARSHALL WACE, LLP trimmed | 929,019 | $37M | 0.6% | 2026-Q1 |
| Man Group plc added | 915,689 | $37M | 0.6% | 2026-Q1 |
| FIRST TRUST ADVISORS LP added | 903,637 | $36M | 0.6% | 2026-Q1 |
| JPMORGAN CHASE & CO added | 2,047,927 | $35M | 0.6% | 2026-Q1 |
| Magnetar Financial LLC added | 869,229 | $35M | 0.6% | 2026-Q1 |
| ALPINE ASSOCIATES MANAGEMENT INC. new | 864,000 | $35M | 0.6% | 2026-Q1 |
| NORGES BANK added | 1,573,601 | $34M | 0.6% | 2026-Q1 |
| ODDO BHF ASSET MANAGEMENT SAS new | 825,000 | $33M | 0.6% | 2026-Q1 |
| Kynam Capital Management, LP trimmed | 825,000 | $33M | 0.6% | 2026-Q1 |
| NORTHERN TRUST CORP added | 738,440 | $30M | 0.5% | 2026-Q1 |
| Weiss Asset Management LP added | 700,000 | $28M | 0.5% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 675,864 | $27M | 0.5% | 2026-Q1 |
| CITIGROUP INC added | 657,223 | $26M | 0.5% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 654,922 | $26M | 0.4% | 2026-Q1 |
| TUDOR INVESTMENT CORP ET AL added | 650,000 | $26M | 0.4% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 584,192 | $24M | 0.4% | 2026-Q1 |
| OSSIAM added | 555,953 | $22M | 0.4% | 2026-Q1 |
| Bank of New York Mellon Corp added | 524,789 | $21M | 0.4% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP trimmed | 521,965 | $21M | 0.4% | 2026-Q1 |
| PRINCIPAL FINANCIAL GROUP INC added | 499,053 | $20M | 0.3% | 2026-Q1 |
| Absolute Gestao de Investimentos Ltda. new | 450,000 | $18M | 0.3% | 2026-Q1 |
| Squarepoint Ops LLC added | 449,796 | $18M | 0.3% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 426,473 | $17M | 0.3% | 2026-Q1 |
| LMR Partners LLP added | 403,622 | $16M | 0.3% | 2026-Q1 |
| Verition Fund Management LLC added | 400,000 | $16M | 0.3% | 2026-Q1 |
| ALLIANCEBERNSTEIN L.P. added | 638,291 | $16M | 0.3% | 2026-Q1 |
| Public Sector Pension Investment Board new | 366,674 | $15M | 0.3% | 2026-Q1 |
| First Trust Capital Management L.P. new | 350,800 | $14M | 0.2% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 340,086 | $14M | 0.2% | 2026-Q1 |
| Invesco Ltd. added | 332,478 | $13M | 0.2% | 2026-Q1 |
| GABELLI FUNDS LLC new | 321,200 | $13M | 0.2% | 2026-Q1 |
| Beck Bode, LLC new | 312,841 | $13M | 0.2% | 2026-Q1 |
| METEORA CAPITAL, LLC new | 300,000 | $12M | 0.2% | 2026-Q1 |
| Jump Financial, LLC added | 291,488 | $12M | 0.2% | 2026-Q1 |
| RHUMBLINE ADVISERS added | 275,540 | $11M | 0.2% | 2026-Q1 |
| JANUS HENDERSON GROUP PLC added | 252,130 | $10M | 0.2% | 2026-Q1 |
| 683 Capital Management, LLC trimmed | 250,000 | $10M | 0.2% | 2026-Q1 |
| CAPSTONE INVESTMENT ADVISORS, LLC added | 250,000 | $10M | 0.2% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 239,469 | $10M | 0.2% | 2026-Q1 |
| Granite Investment Partners, LLC trimmed | 231,917 | $9M | 0.2% | 2026-Q1 |
| Legal & General Group Plc added | 228,255 | $9M | 0.2% | 2026-Q1 |
| Westchester Capital Management, LLC new | 227,489 | $9M | 0.2% | 2026-Q1 |
| Nuveen, LLC trimmed | 220,114 | $9M | 0.2% | 2026-Q1 |
| Jefferies Financial Group Inc. added | 219,000 | $9M | 0.2% | 2026-Q1 |
| BANK OF MONTREAL /CAN/ added | 215,041 | $9M | 0.1% | 2026-Q1 |
| SPHERA FUNDS MANAGEMENT LTD. trimmed | 214,914 | $9M | 0.1% | 2026-Q1 |
| Trexquant Investment LP added | 205,219 | $8M | 0.1% | 2026-Q1 |
| GABELLI & Co INVESTMENT ADVISERS, INC. new | 200,600 | $8M | 0.1% | 2026-Q1 |
| Pictet Asset Management Holding SA added | 426,821 | $8M | 0.1% | 2026-Q1 |
| D. E. Shaw & Co., Inc. trimmed | 186,853 | $8M | 0.1% | 2026-Q1 |
| AMERIPRISE FINANCIAL INC trimmed | 183,578 | $7M | 0.1% | 2026-Q1 |
| BOOTHBAY FUND MANAGEMENT, LLC added | 183,522 | $7M | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC added | 180,471 | $7M | 0.1% | 2026-Q1 |
| VANGUARD GROUP INC trimmed | 9,897,968 | $249M | 4.2% | 2025-Q4 stale |
| Polar Capital Holdings Plc added | 3,706,510 | $93M | 1.6% | 2025-Q4 stale |
| EcoR1 Capital, LLC trimmed | 3,447,156 | $78M | 1.3% | 2025-Q3 stale |
| Siren, L.L.C. | 2,578,396 | $65M | 1.1% | 2025-Q4 stale |
| ORBIMED ADVISORS LLC added | 2,429,868 | $61M | 1.0% | 2025-Q4 stale |
| JENNISON ASSOCIATES LLC trimmed | 1,504,299 | $38M | 0.6% | 2025-Q4 stale |
| BANK OF NOVA SCOTIA trimmed | 1,070,141 | $27M | 0.5% | 2025-Q4 stale |
| Octagon Capital Advisors LP | 903,500 | $20M | 0.3% | 2025-Q3 stale |
| BRAIDWELL LP trimmed | 1,121,034 | $19M | 0.3% | 2025-Q2 stale |
| NATIONAL BANK OF CANADA /FI/ trimmed | 782,701 | $17M | 0.3% | 2025-Q1 stale |
| Boxer Capital Management, LLC trimmed | 713,000 | $16M | 0.3% | 2025-Q1 stale |
| Camber Capital Management LP new | 850,000 | $15M | 0.3% | 2025-Q2 stale |
| Simplify Asset Management Inc. added | 538,008 | $14M | 0.2% | 2025-Q4 stale |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 461,186 | $12M | 0.2% | 2025-Q4 stale |
| Capitolis Liquid Global Markets LLC new | 544,600 | $9M | 0.2% | 2025-Q2 stale |
| Rhenman & Partners Asset Management AB added | 374,450 | $9M | 0.2% | 2025-Q4 stale |
| SCHRODER INVESTMENT MANAGEMENT GROUP added | 329,134 | $8M | 0.1% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.