Who owns ANNX (ANNX)
Which tracked institutional funds hold ANNX, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See ANNX company fundamentals →
Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
61 tracked funds added or opened ANNX while 31 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
ANNX’s largest tracked holder by dollar value, Redmile Group, LLC, sizes it at 5.3% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 5.3pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in ANNX divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 217 tracked filers holding ANNX, 150 increased or opened the position and 69 reduced or closed it; over the same quarter, open-market insider Form 4s were net purchases.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in ANNX between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 18
- VANGUARD CAPITAL MANAGEMENT LLC$33M
- Siren, L.L.C.$22M
- GREAT POINT PARTNERS LLC$14M
- VANGUARD PORTFOLIO MANAGEMENT LLC$8M
- Y-Intercept (Hong Kong) Ltd$7M
- VANGUARD FIDUCIARY TRUST CO$5M
Full exits 5
- VANGUARD GROUP INC$34M
- SPHERA FUNDS MANAGEMENT LTD.$7M
- SummitTX Capital, L.P.$2M
- Jump Financial, LLC$617K
- Caption Management, LLC$600K
Largest adds
- Redmile Group, LLC$30M
- BlackRock, Inc.$16M
- BANK OF AMERICA CORP /DE/$16M
- STATE STREET CORP$15M
- MAK CAPITAL ONE LLC$11M
- Nuveen, LLC$9M
Largest trims
- Longaeva Partners L.P.$12M
- MILLENNIUM MANAGEMENT LLC$7M
- Woodline Partners LP$7M
- J. Goldman & Co LP$4M
- ADAGE CAPITAL PARTNERS GP, L.L.C.$4M
- Tetragon Partners GP Ltd$3M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| Redmile Group, LLC added | 14,549,768 | $81M | 8.8% | 2026-Q1 |
| BlackRock, Inc. added | 10,938,509 | $61M | 6.6% | 2026-Q1 |
| FMR LLC trimmed | 9,913,739 | $55M | 6.0% | 2026-Q1 |
| BVF INC/IL trimmed | 8,698,173 | $48M | 5.3% | 2026-Q1 |
| STATE STREET CORP added | 6,919,255 | $38M | 4.2% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 5,956,589 | $33M | 3.6% | 2026-Q1 |
| Bain Capital Life Sciences Investors, LLC trimmed | 5,212,674 | $29M | 3.2% | 2026-Q1 |
| Bellevue Group AG | 5,157,290 | $29M | 3.1% | 2026-Q1 |
| MAK CAPITAL ONE LLC added | 4,724,043 | $26M | 2.9% | 2026-Q1 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. trimmed | 4,300,000 | $24M | 2.6% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ added | 4,259,995 | $24M | 2.6% | 2026-Q1 |
| Nuveen, LLC added | 4,246,330 | $24M | 2.6% | 2026-Q1 |
| Siren, L.L.C. new | 3,958,646 | $22M | 2.4% | 2026-Q1 |
| BALYASNY ASSET MANAGEMENT L.P. added | 3,886,909 | $22M | 2.4% | 2026-Q1 |
| AMERIPRISE FINANCIAL INC trimmed | 3,449,121 | $19M | 2.1% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 3,377,823 | $19M | 2.0% | 2026-Q1 |
| Qube Research & Technologies Ltd added | 3,114,314 | $17M | 1.9% | 2026-Q1 |
| Palo Alto Investors LP added | 2,948,090 | $16M | 1.8% | 2026-Q1 |
| MORGAN STANLEY trimmed | 2,735,970 | $15M | 1.7% | 2026-Q1 |
| GREAT POINT PARTNERS LLC new | 2,500,000 | $14M | 1.5% | 2026-Q1 |
| Woodline Partners LP trimmed | 2,337,137 | $13M | 1.4% | 2026-Q1 |
| Opaleye Management Inc. trimmed | 2,331,761 | $13M | 1.4% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC added | 2,152,880 | $12M | 1.3% | 2026-Q1 |
| Point72 Asset Management, L.P. added | 1,871,795 | $10M | 1.1% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 1,483,090 | $8M | 0.9% | 2026-Q1 |
| Y-Intercept (Hong Kong) Ltd added | 1,319,913 | $7M | 0.8% | 2026-Q1 |
| Tetragon Partners GP Ltd trimmed | 1,292,455 | $7M | 0.8% | 2026-Q1 |
| UBS Group AG added | 1,245,941 | $7M | 0.8% | 2026-Q1 |
| MILLENNIUM MANAGEMENT LLC trimmed | 1,238,678 | $7M | 0.8% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 1,102,445 | $6M | 0.7% | 2026-Q1 |
| NORTHERN TRUST CORP added | 1,086,902 | $6M | 0.7% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 924,078 | $5M | 0.6% | 2026-Q1 |
| KENNEDY CAPITAL MANAGEMENT LLC added | 912,323 | $5M | 0.6% | 2026-Q1 |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ trimmed | 903,368 | $5M | 0.5% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 888,552 | $5M | 0.5% | 2026-Q1 |
| MARSHALL WACE, LLP added | 832,131 | $5M | 0.5% | 2026-Q1 |
| Invesco Ltd. trimmed | 763,005 | $4M | 0.5% | 2026-Q1 |
| AQR CAPITAL MANAGEMENT LLC trimmed | 759,556 | $4M | 0.5% | 2026-Q1 |
| ACADIAN ASSET MANAGEMENT LLC trimmed | 758,232 | $4M | 0.5% | 2026-Q1 |
| Russell Investments Group, Ltd. added | 711,380 | $4M | 0.4% | 2026-Q1 |
| WELLS FARGO & COMPANY/MN added | 698,739 | $4M | 0.4% | 2026-Q1 |
| D. E. Shaw & Co., Inc. trimmed | 678,440 | $4M | 0.4% | 2026-Q1 |
| Parkman Healthcare Partners LLC added | 674,013 | $4M | 0.4% | 2026-Q1 |
| Ensign Peak Advisors, Inc added | 625,097 | $3M | 0.4% | 2026-Q1 |
| Longaeva Partners L.P. trimmed | 620,401 | $3M | 0.4% | 2026-Q1 |
| CITADEL ADVISORS LLC added | 600,135 | $3M | 0.4% | 2026-Q1 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 583,913 | $3M | 0.4% | 2026-Q1 |
| Ikarian Capital, LLC added | 580,244 | $3M | 0.4% | 2026-Q1 |
| SIRIOS CAPITAL MANAGEMENT L P trimmed | 575,063 | $3M | 0.3% | 2026-Q1 |
| DEUTSCHE BANK AG\ added | 562,181 | $3M | 0.3% | 2026-Q1 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 544,300 | $3M | 0.3% | 2026-Q1 |
| Hennion & Walsh Asset Management, Inc. trimmed | 509,689 | $3M | 0.3% | 2026-Q1 |
| SILVERARC CAPITAL MANAGEMENT, LLC added | 496,461 | $3M | 0.3% | 2026-Q1 |
| Board of Trustees of The Leland Stanford Junior University | 482,550 | $3M | 0.3% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP added | 471,391 | $3M | 0.3% | 2026-Q1 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC new | 462,068 | $3M | 0.3% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ trimmed | 428,720 | $2M | 0.3% | 2026-Q1 |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC trimmed | 416,698 | $2M | 0.3% | 2026-Q1 |
| Trexquant Investment LP added | 403,657 | $2M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp added | 395,019 | $2M | 0.2% | 2026-Q1 |
| Susquehanna Portfolio Strategies, LLC added | 360,319 | $2M | 0.2% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 325,908 | $2M | 0.2% | 2026-Q1 |
| JPMORGAN CHASE & CO added | 323,894 | $2M | 0.2% | 2026-Q1 |
| Cinctive Capital Management LP trimmed | 268,640 | $1M | 0.2% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 255,371 | $1M | 0.2% | 2026-Q1 |
| Swiss National Bank added | 236,000 | $1M | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC added | 203,269 | $1M | 0.1% | 2026-Q1 |
| SEI INVESTMENTS CO added | 203,236 | $1M | 0.1% | 2026-Q1 |
| Rosalind Advisors, Inc. new | 200,000 | $1M | 0.1% | 2026-Q1 |
| IEQ CAPITAL, LLC added | 195,764 | $1M | 0.1% | 2026-Q1 |
| Ishara Investments LP trimmed | 174,250 | $965K | 0.1% | 2026-Q1 |
| Engineers Gate Manager LP added | 174,141 | $965K | 0.1% | 2026-Q1 |
| J. Goldman & Co LP trimmed | 170,817 | $946K | 0.1% | 2026-Q1 |
| BOOTHBAY FUND MANAGEMENT, LLC added | 166,164 | $921K | 0.1% | 2026-Q1 |
| RHUMBLINE ADVISERS added | 159,670 | $885K | 0.1% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP trimmed | 158,640 | $879K | 0.1% | 2026-Q1 |
| ALGERT GLOBAL LLC added | 154,840 | $858K | 0.1% | 2026-Q1 |
| JACOBS LEVY EQUITY MANAGEMENT, INC trimmed | 148,941 | $825K | 0.1% | 2026-Q1 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE added | 134,786 | $747K | 0.1% | 2026-Q1 |
| DIADEMA PARTNERS LP trimmed | 132,916 | $736K | 0.1% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 130,647 | $724K | 0.1% | 2026-Q1 |
| Schonfeld Strategic Advisors LLC trimmed | 123,282 | $683K | 0.1% | 2026-Q1 |
| DAFNA Capital Management LLC trimmed | 117,812 | $653K | 0.1% | 2026-Q1 |
| VICTORY CAPITAL MANAGEMENT INC added | 115,527 | $640K | 0.1% | 2026-Q1 |
| Man Group plc added | 109,222 | $605K | 0.1% | 2026-Q1 |
| ALLIANCEBERNSTEIN L.P. trimmed | 119,050 | $598K | 0.1% | 2026-Q1 |
| SCS Capital Management LLC new | 99,000 | $548K | 0.1% | 2026-Q1 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC trimmed | 97,800 | $542K | 0.1% | 2026-Q1 |
| Connor, Clark & Lunn Investment Management Ltd. trimmed | 92,707 | $514K | 0.1% | 2026-Q1 |
| VANGUARD GROUP INC added | 6,855,389 | $34M | 3.8% | 2025-Q4 stale |
| Sio Capital Management, LLC added | 4,095,764 | $10M | 1.1% | 2025-Q2 stale |
| Candriam S.C.A. | 2,534,230 | $8M | 0.8% | 2025-Q3 stale |
| SPHERA FUNDS MANAGEMENT LTD. trimmed | 1,316,212 | $7M | 0.7% | 2025-Q4 stale |
| Logos Global Management LP trimmed | 2,410,000 | $6M | 0.6% | 2025-Q2 stale |
| Rhenman & Partners Asset Management AB added | 823,000 | $3M | 0.3% | 2025-Q3 stale |
| SummitTX Capital, L.P. added | 438,497 | $2M | 0.2% | 2025-Q4 stale |
| Walleye Capital LLC trimmed | 794,639 | $2M | 0.2% | 2025-Q2 stale |
| Point72 Europe (London) LLP added | 302,861 | $924K | 0.1% | 2025-Q3 stale |
| Jump Financial, LLC added | 122,858 | $617K | 0.1% | 2025-Q4 stale |
| Caption Management, LLC trimmed | 119,491 | $600K | 0.1% | 2025-Q4 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.