Who owns AnaptysBio (ANAB)
Which tracked institutional funds hold ANAB, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See ANAB company fundamentals →
Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
90 tracked funds added or opened ANAB while 32 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
ANAB’s largest tracked holder by dollar value, EcoR1 Capital, LLC, sizes it at 26.4% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 26.4pp conviction gap — its largest holder concentrates the name more heavily than the typical one.
Book-share is each fund’s reported value in ANAB divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2026-Q1 and 2026-Q2, across 205 tracked filers holding ANAB, 115 increased or opened the position and 107 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in ANAB between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 22
- FIRST TRUST ADVISORS LP$17M
- Coppell Advisory Solutions LLC$17M
- Empowered Funds, LLC$14M
- DIMENSIONAL FUND ADVISORS LP$13M
- Greenhaven Road Investment Management, L.P.$12M
- DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main$6M
Full exits 18
- Synergy Asset Management, LLC$18M
- JANE STREET GROUP, LLC$5M
- Fisher Asset Management, LLC$3M
- Point72 Asset Management, L.P.$3M
- Penserra Capital Management LLC$2M
- HRT FINANCIAL LP$2M
Largest adds
- EcoR1 Capital, LLC$95M
- STATE STREET CORP$32M
- BlackRock, Inc.$31M
- Woodline Partners LP$29M
- MILLENNIUM MANAGEMENT LLC$28M
- Sanofi$25M
Largest trims
- MORGAN STANLEY$38M
- FMR LLC$8M
- TWO SIGMA INVESTMENTS, LP$8M
- BNP PARIBAS FINANCIAL MARKETS$5M
- HighMark Wealth Management LLC$3M
- Trexquant Investment LP$2M
Institutional holders
One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| EcoR1 Capital, LLC | 7,880,094 | $532M | 26.3% | 2026-Q2 |
| BlackRock, Inc. added | 1,844,049 | $124M | 6.2% | 2026-Q2 |
| TANG CAPITAL MANAGEMENT LLC | 1,330,879 | $90M | 4.4% | 2026-Q2 |
| STATE STREET CORP added | 1,286,194 | $87M | 4.3% | 2026-Q2 |
| VANGUARD CAPITAL MANAGEMENT LLC added | 906,233 | $61M | 3.0% | 2026-Q2 |
| Affinity Asset Advisors, LLC trimmed | 826,109 | $56M | 2.8% | 2026-Q2 |
| Sanofi | 821,917 | $55M | 2.7% | 2026-Q2 |
| MILLENNIUM MANAGEMENT LLC added | 807,316 | $54M | 2.7% | 2026-Q2 |
| Woodline Partners LP added | 717,014 | $48M | 2.4% | 2026-Q2 |
| 683 Capital Management, LLC added | 660,000 | $45M | 2.2% | 2026-Q2 |
| GEODE CAPITAL MANAGEMENT, LLC added | 637,873 | $43M | 2.1% | 2026-Q2 |
| Palo Alto Investors LP trimmed | 603,489 | $41M | 2.0% | 2026-Q2 |
| GOLDMAN SACHS GROUP INC added | 584,070 | $39M | 2.0% | 2026-Q2 |
| First Light Asset Management, LLC added | 582,004 | $39M | 1.9% | 2026-Q2 |
| D. E. Shaw & Co., Inc. trimmed | 539,666 | $36M | 1.8% | 2026-Q2 |
| VANGUARD PORTFOLIO MANAGEMENT LLC added | 527,858 | $36M | 1.8% | 2026-Q2 |
| Apis Capital Advisors, LLC added | 497,000 | $34M | 1.7% | 2026-Q2 |
| Sofinnova Investments, Inc. added | 493,536 | $33M | 1.6% | 2026-Q2 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP trimmed | 488,651 | $33M | 1.6% | 2026-Q2 |
| Nuveen, LLC added | 420,664 | $28M | 1.4% | 2026-Q2 |
| BANK OF AMERICA CORP /DE/ trimmed | 417,812 | $28M | 1.4% | 2026-Q2 |
| CITADEL ADVISORS LLC added | 394,373 | $27M | 1.3% | 2026-Q2 |
| FEDERATED HERMES, INC. added | 391,667 | $26M | 1.3% | 2026-Q2 |
| Squarepoint Ops LLC added | 324,446 | $22M | 1.1% | 2026-Q2 |
| TWO SIGMA INVESTMENTS, LP trimmed | 262,995 | $18M | 0.9% | 2026-Q2 |
| FIRST TRUST ADVISORS LP new | 258,989 | $17M | 0.9% | 2026-Q2 |
| MORGAN STANLEY trimmed | 257,091 | $17M | 0.9% | 2026-Q2 |
| FMR LLC trimmed | 240,511 | $16M | 0.8% | 2026-Q2 |
| Qube Research & Technologies Ltd trimmed | 228,777 | $15M | 0.8% | 2026-Q2 |
| HSBC HOLDINGS PLC added | 216,949 | $15M | 0.7% | 2026-Q2 |
| Empowered Funds, LLC new | 206,010 | $14M | 0.7% | 2026-Q2 |
| NORTHERN TRUST CORP added | 202,767 | $14M | 0.7% | 2026-Q2 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC added | 202,305 | $14M | 0.7% | 2026-Q2 |
| Invesco Ltd. added | 202,056 | $14M | 0.7% | 2026-Q2 |
| DIMENSIONAL FUND ADVISORS LP added | 185,444 | $13M | 0.6% | 2026-Q2 |
| Greenhaven Road Investment Management, L.P. new | 171,059 | $12M | 0.6% | 2026-Q2 |
| VICTORY CAPITAL MANAGEMENT INC added | 169,227 | $11M | 0.6% | 2026-Q2 |
| MACKENZIE FINANCIAL CORP added | 150,979 | $10M | 0.5% | 2026-Q2 |
| UBS Group AG added | 146,832 | $10M | 0.5% | 2026-Q2 |
| VANGUARD FIDUCIARY TRUST CO added | 146,724 | $10M | 0.5% | 2026-Q2 |
| Connor, Clark & Lunn Investment Management Ltd. trimmed | 141,026 | $10M | 0.5% | 2026-Q2 |
| Ensign Peak Advisors, Inc trimmed | 107,096 | $7M | 0.4% | 2026-Q2 |
| FRANKLIN RESOURCES INC added | 106,949 | $7M | 0.4% | 2026-Q2 |
| CITIGROUP INC added | 99,114 | $7M | 0.3% | 2026-Q2 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 93,732 | $6M | 0.3% | 2026-Q2 |
| PRUDENTIAL FINANCIAL INC added | 85,932 | $6M | 0.3% | 2026-Q2 |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main new | 83,942 | $6M | 0.3% | 2026-Q2 |
| JPMORGAN CHASE & CO added | 80,236 | $5M | 0.3% | 2026-Q2 |
| Granahan Investment Management, LLC added | 75,962 | $5M | 0.3% | 2026-Q2 |
| Irenic Capital Management LP new | 70,447 | $5M | 0.2% | 2026-Q2 |
| Eversept Partners, LP added | 69,983 | $5M | 0.2% | 2026-Q2 |
| JACOBS LEVY EQUITY MANAGEMENT, INC added | 62,336 | $4M | 0.2% | 2026-Q2 |
| STATE OF WISCONSIN INVESTMENT BOARD added | 61,753 | $4M | 0.2% | 2026-Q2 |
| RENAISSANCE TECHNOLOGIES LLC trimmed | 58,300 | $4M | 0.2% | 2026-Q2 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 57,555 | $4M | 0.2% | 2026-Q2 |
| Bank of New York Mellon Corp added | 56,401 | $4M | 0.2% | 2026-Q2 |
| DEUTSCHE BANK AG\ trimmed | 46,884 | $3M | 0.2% | 2026-Q2 |
| AQR CAPITAL MANAGEMENT LLC added | 46,323 | $3M | 0.2% | 2026-Q2 |
| MARSHALL WACE, LLP trimmed | 43,822 | $3M | 0.1% | 2026-Q2 |
| Bleakley Financial Group, LLC trimmed | 42,761 | $3M | 0.1% | 2026-Q2 |
| WELLINGTON MANAGEMENT GROUP LLP added | 41,796 | $3M | 0.1% | 2026-Q2 |
| WELLS FARGO & COMPANY/MN added | 41,707 | $3M | 0.1% | 2026-Q2 |
| HighMark Wealth Management LLC trimmed | 39,716 | $3M | 0.1% | 2026-Q2 |
| CAPITAL FUND MANAGEMENT S.A. new | 39,142 | $3M | 0.1% | 2026-Q2 |
| Trexquant Investment LP trimmed | 35,404 | $2M | 0.1% | 2026-Q2 |
| Atom Investors LP new | 33,917 | $2M | 0.1% | 2026-Q2 |
| ALLIANCEBERNSTEIN L.P. added | 32,820 | $2M | 0.1% | 2026-Q2 |
| PRICE T ROWE ASSOCIATES INC /MD/ added | 32,374 | $2M | 0.1% | 2026-Q2 |
| Swiss National Bank added | 31,700 | $2M | 0.1% | 2026-Q2 |
| Voleon Capital Management LP new | 31,425 | $2M | 0.1% | 2026-Q2 |
| Tidal Investments LLC trimmed | 31,270 | $2M | 0.1% | 2026-Q2 |
| Tema ETFs LLC added | 31,270 | $2M | 0.1% | 2026-Q2 |
| Moody Aldrich Partners LLC trimmed | 30,926 | $2M | 0.1% | 2026-Q2 |
| Aquatic Capital Management LLC added | 30,813 | $2M | 0.1% | 2026-Q2 |
| SummitTX Capital, L.P. added | 28,779 | $2M | 0.1% | 2026-Q2 |
| RHUMBLINE ADVISERS added | 26,346 | $2M | 0.1% | 2026-Q2 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC trimmed | 23,310 | $2M | 0.1% | 2026-Q2 |
| BURNEY CO/ new | 22,557 | $2M | 0.1% | 2026-Q2 |
| Rafferty Asset Management, LLC trimmed | 21,864 | $1M | 0.1% | 2026-Q2 |
| XTX Topco Ltd trimmed | 21,411 | $1M | 0.1% | 2026-Q2 |
| HUSSMAN STRATEGIC ADVISORS, INC. | 21,000 | $1M | 0.1% | 2026-Q2 |
| TUDOR INVESTMENT CORP ET AL added | 20,019 | $1M | 0.1% | 2026-Q2 |
| CREDIT AGRICOLE S A | 20,000 | $1M | 0.1% | 2026-Q2 |
| MARTINGALE ASSET MANAGEMENT L P trimmed | 19,942 | $1M | 0.1% | 2026-Q2 |
| Creative Planning added | 18,773 | $1M | 0.1% | 2026-Q2 |
| Y-Intercept (Hong Kong) Ltd trimmed | 18,468 | $1M | 0.1% | 2026-Q2 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM added | 17,629 | $1M | 0.1% | 2026-Q2 |
| LOS ANGELES CAPITAL MANAGEMENT LLC added | 17,536 | $1M | 0.1% | 2026-Q2 |
| VIRGINIA RETIREMENT SYSTEMS ET Al added | 17,250 | $1M | 0.1% | 2026-Q2 |
| Diametric Capital, LP new | 16,868 | $1M | 0.1% | 2026-Q2 |
| CANADA PENSION PLAN INVESTMENT BOARD added | 16,500 | $1M | 0.1% | 2026-Q2 |
| Legal & General Group Plc added | 16,415 | $1M | 0.1% | 2026-Q2 |
| Russell Investments Group, Ltd. added | 16,301 | $1M | 0.1% | 2026-Q2 |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ new | 15,870 | $1M | 0.1% | 2026-Q2 |
| Cresset Asset Management, LLC added | 14,412 | $973K | 0.0% | 2026-Q2 |
| Vanguard Global Advisers, LLC added | 13,919 | $940K | 0.0% | 2026-Q2 |
| Zurcher Kantonalbank (Zurich Cantonalbank) added | 13,405 | $905K | 0.0% | 2026-Q2 |
| Brevan Howard Capital Management LP added | 13,329 | $900K | 0.0% | 2026-Q2 |
| SEI INVESTMENTS CO added | 13,161 | $888K | 0.0% | 2026-Q2 |
| Coppell Advisory Solutions LLC new | 3,638 | $17M | 0.8% | 2026-Q2 |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.