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Institutional Ownership · SEC Form 13F

Who owns Agios Pharmaceuticals (AGIO)


Which tracked institutional funds hold AGIO, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See AGIO company fundamentals →

Ownership as of the 2026-Q2 13F filings (latest filed 2026-09-22). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

224
Institutional holders
64M
Shares held (tracked funds)

How the tape is positioned

88 tracked funds added or opened AGIO while 52 trimmed or exited it between 2026-Q1 and 2026-Q2 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

AGIO’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes AGIO more heavily than its largest holder by dollar value does.

Book-share is each fund’s reported value in AGIO divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2026-Q1 and 2026-Q2, across 224 tracked filers holding AGIO, 129 increased or opened the position and 109 reduced or closed it; over the same quarter, open-market insider Form 4s were net sales.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in AGIO between the 2026-Q1 and 2026-Q2 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 19

  • Defilade Capital Management, L.P.$20M
  • Jump Financial, LLC$7M
  • FIRST TRUST ADVISORS LP$6M
  • Ishara Investments LP$6M
  • BOOTHBAY FUND MANAGEMENT, LLC$6M
  • Jain Global LLC$3M

Full exits 26

  • T. Rowe Price Investment Management, Inc.$50M
  • MPM BIOIMPACT LLC$44M
  • Frazier Life Sciences Management, L.P.$42M
  • GW&K Investment Management, LLC$41M
  • Artisan Partners Limited Partnership$16M
  • Vestal Point Capital, LP$15M

Largest adds

  • BlackRock, Inc.$45M
  • ADAR1 Capital Management, LLC$43M
  • Lynx1 Capital Management LP$38M
  • UBS Group AG$32M
  • NOMURA ASSET MANAGEMENT INTERNATIONAL INC.$28M
  • FARALLON CAPITAL MANAGEMENT, L.L.C.$27M

Largest trims

  • WELLINGTON MANAGEMENT GROUP LLP$19M
  • MARSHALL WACE, LLP$10M
  • ArrowMark Colorado Holdings LLC$9M
  • Rock Springs Capital Management LP$7M
  • BNP PARIBAS ASSET MANAGEMENT Holding S.A.$6M
  • Seven Fleet Capital Management LP$5M

Institutional holders

One row per tracked fund, most shares held first (every row is from one quarter; reported value breaks ties). “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding.

FundSharesReported value% of valueQuarter
BlackRock, Inc. added6,455,997$240M10.2%2026-Q2
FARALLON CAPITAL MANAGEMENT, L.L.C. added5,917,400$220M9.3%2026-Q2
STATE STREET CORP added3,533,633$131M5.6%2026-Q2
Lynx1 Capital Management LP added3,408,937$127M5.4%2026-Q2
D. E. Shaw & Co., Inc. added3,107,005$115M4.9%2026-Q2
VANGUARD PORTFOLIO MANAGEMENT LLC added2,898,197$108M4.6%2026-Q2
VANGUARD CAPITAL MANAGEMENT LLC added2,681,845$100M4.2%2026-Q2
ARMISTICE CAPITAL, LLC trimmed2,400,000$89M3.8%2026-Q2
Erste Asset Management GmbH trimmed2,154,900$82M3.5%2026-Q2
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. added2,110,809$78M3.3%2026-Q2
GEODE CAPITAL MANAGEMENT, LLC added1,574,268$58M2.5%2026-Q2
SUSQUEHANNA INTERNATIONAL GROUP, LLP added1,375,558$51M2.2%2026-Q2
ADAR1 Capital Management, LLC added1,288,053$48M2.0%2026-Q2
BNP PARIBAS ASSET MANAGEMENT Holding S.A. trimmed1,280,044$48M2.0%2026-Q2
DIMENSIONAL FUND ADVISORS LP added1,248,738$46M2.0%2026-Q2
GOLDMAN SACHS GROUP INC added1,150,932$43M1.8%2026-Q2
UBS Group AG added985,831$37M1.6%2026-Q2
MORGAN STANLEY trimmed963,256$36M1.5%2026-Q2
Nuveen, LLC added873,560$32M1.4%2026-Q2
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP added810,530$30M1.3%2026-Q2
Foresite Capital Management VI LLC added785,000$29M1.2%2026-Q2
CITADEL ADVISORS LLC added732,687$27M1.2%2026-Q2
AQR CAPITAL MANAGEMENT LLC added684,340$25M1.1%2026-Q2
Parkman Healthcare Partners LLC added669,046$25M1.1%2026-Q2
SCS Capital Management LLC612,850$23M1.0%2026-Q2
Qube Research & Technologies Ltd added597,638$22M0.9%2026-Q2
NORTHERN TRUST CORP added554,709$21M0.9%2026-Q2
Defilade Capital Management, L.P. new546,848$20M0.9%2026-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added538,128$20M0.8%2026-Q2
TWO SIGMA INVESTMENTS, LP added536,380$20M0.8%2026-Q2
Rock Springs Capital Management LP trimmed532,563$20M0.8%2026-Q2
Schonfeld Strategic Advisors LLC added520,083$19M0.8%2026-Q2
BANK OF AMERICA CORP /DE/ trimmed507,869$19M0.8%2026-Q2
Point72 Asset Management, L.P. added506,344$19M0.8%2026-Q2
JANE STREET GROUP, LLC trimmed492,598$18M0.8%2026-Q2
Legal & General Group Plc added434,719$16M0.7%2026-Q2
VANGUARD FIDUCIARY TRUST CO added395,868$15M0.6%2026-Q2
PANAGORA ASSET MANAGEMENT INC added373,931$14M0.6%2026-Q2
KENNEDY CAPITAL MANAGEMENT LLC added373,230$14M0.6%2026-Q2
JPMORGAN CHASE & CO added359,756$14M0.6%2026-Q2
Connor, Clark & Lunn Investment Management Ltd. trimmed359,550$13M0.6%2026-Q2
Squarepoint Ops LLC added321,138$12M0.5%2026-Q2
Ensign Peak Advisors, Inc added297,630$11M0.5%2026-Q2
BNP PARIBAS FINANCIAL MARKETS trimmed269,383$10M0.4%2026-Q2
ALGERT GLOBAL LLC trimmed248,007$9M0.4%2026-Q2
PRICE T ROWE ASSOCIATES INC /MD/ trimmed218,966$8M0.3%2026-Q2
Palo Alto Investors LP213,601$8M0.3%2026-Q2
Tetragon Partners GP Ltd added205,579$8M0.3%2026-Q2
Bank of New York Mellon Corp added198,685$7M0.3%2026-Q2
Jump Financial, LLC added182,773$7M0.3%2026-Q2
Invesco Ltd. added168,153$6M0.3%2026-Q2
FIRST TRUST ADVISORS LP added165,587$6M0.3%2026-Q2
Ishara Investments LP added164,000$6M0.3%2026-Q2
GROUP ONE TRADING LLC trimmed151,994$6M0.2%2026-Q2
BOOTHBAY FUND MANAGEMENT, LLC added149,886$6M0.2%2026-Q2
MARSHALL WACE, LLP trimmed138,800$5M0.2%2026-Q2
AMERICAN CENTURY COMPANIES INC added134,512$5M0.2%2026-Q2
Man Group plc trimmed124,466$5M0.2%2026-Q2
ArrowMark Colorado Holdings LLC trimmed117,714$4M0.2%2026-Q2
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added116,909$4M0.2%2026-Q2
Pictet Asset Management Holding SA trimmed111,861$4M0.2%2026-Q2
Swiss National Bank added111,660$4M0.2%2026-Q2
CAPITAL FUND MANAGEMENT S.A. trimmed104,080$4M0.2%2026-Q2
Assenagon Asset Management S.A. added103,955$4M0.2%2026-Q2
Universal- Beteiligungs- und Servicegesellschaft mbH added99,726$4M0.2%2026-Q2
Knott David M Jr added95,058$4M0.1%2026-Q2
Trexquant Investment LP added93,539$3M0.1%2026-Q2
Jain Global LLC added91,647$3M0.1%2026-Q2
CITIGROUP INC added89,167$3M0.1%2026-Q2
RHUMBLINE ADVISERS added79,441$3M0.1%2026-Q2
Campbell & CO Investment Adviser LLC added73,095$3M0.1%2026-Q2
Exome Asset Management LLC trimmed70,500$3M0.1%2026-Q2
Edgestream Partners, L.P. trimmed70,195$3M0.1%2026-Q2
Russell Investments Group, Ltd. added66,856$2M0.1%2026-Q2
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM trimmed66,796$2M0.1%2026-Q2
TUDOR INVESTMENT CORP ET AL added65,779$2M0.1%2026-Q2
DEUTSCHE BANK AG\ added62,228$2M0.1%2026-Q2
ALLIANCEBERNSTEIN L.P. added61,864$2M0.1%2026-Q2
ALPS ADVISORS INC added60,059$2M0.1%2026-Q2
Seven Fleet Capital Management LP trimmed56,900$2M0.1%2026-Q2
Rafferty Asset Management, LLC trimmed55,580$2M0.1%2026-Q2
Engineers Gate Manager LP added53,912$2M0.1%2026-Q2
WELLS FARGO & COMPANY/MN added53,240$2M0.1%2026-Q2
VANGUARD ASSET MANAGEMENT, Ltd trimmed52,050$2M0.1%2026-Q2
XTX Topco Ltd trimmed50,366$2M0.1%2026-Q2
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main new49,764$2M0.1%2026-Q2
BARCLAYS PLC trimmed48,300$2M0.1%2026-Q2
Quantinno Capital Management LP added43,514$2M0.1%2026-Q2
MARTINGALE ASSET MANAGEMENT L P added43,009$2M0.1%2026-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. trimmed41,455$2M0.1%2026-Q2
IEQ CAPITAL, LLC added40,404$1M0.1%2026-Q2
Virtus Investment Advisers, LLC added39,473$1M0.1%2026-Q2
Caption Management, LLC added39,249$1M0.1%2026-Q2
FMR LLC added39,072$1M0.1%2026-Q2
Aquatic Capital Management LLC added38,627$1M0.1%2026-Q2
MANUFACTURERS LIFE INSURANCE COMPANY, THE trimmed37,727$1M0.1%2026-Q2
SEI INVESTMENTS CO trimmed35,089$1M0.1%2026-Q2
EDGEWOOD MANAGEMENT LLC35,000$1M0.1%2026-Q2
MetLife Investment Management, LLC added34,470$1M0.1%2026-Q2
Hennion & Walsh Asset Management, Inc. trimmed33,574$1M0.1%2026-Q2

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership