Who owns Agios Pharmaceuticals, Inc. (AGIO)
Which tracked institutional funds hold AGIO, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See AGIO company fundamentals →
Ownership as of the 2026-Q1 13F filings (latest filed 2026-05-18). 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.
How the tape is positioned
92 tracked funds added or opened AGIO while 51 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.
A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.
Conviction spread
AGIO’s largest tracked holder by dollar value, BlackRock, Inc., sizes it at 0.0% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 0.0pp gap the other way — the median holder sizes AGIO more heavily than its largest holder by dollar value does.
Book-share is each fund’s reported value in AGIO divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.
Institutional & insider positioning
Between 2025-Q4 and 2026-Q1, across 234 tracked filers holding AGIO, 118 increased or opened the position and 123 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.
This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.
New buyers & exits
Funds opening or closing a position in AGIO between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.
New buyers 18
- VANGUARD CAPITAL MANAGEMENT LLC$89M
- VANGUARD PORTFOLIO MANAGEMENT LLC$88M
- VANGUARD FIDUCIARY TRUST CO$13M
- ARROWSTREET CAPITAL, LIMITED PARTNERSHIP$8M
- Schonfeld Strategic Advisors LLC$7M
- Eversept Partners, LP$7M
Full exits 20
- VANGUARD GROUP INC$140M
- TCG Crossover Management, LLC$32M
- MOORE CAPITAL MANAGEMENT, LP$4M
- Allianz Asset Management GmbH$4M
- HighVista Strategies LLC$4M
- Ikarian Capital, LLC$3M
Largest adds
- Lynx1 Capital Management LP$86M
- BlackRock, Inc.$52M
- FARALLON CAPITAL MANAGEMENT LLC$52M
- T. Rowe Price Investment Management, Inc.$50M
- D. E. Shaw & Co., Inc.$41M
- STATE STREET CORP$29M
Largest trims
- Capital International Investors$18M
- BALYASNY ASSET MANAGEMENT L.P.$17M
- CITADEL ADVISORS LLC$16M
- MILLENNIUM MANAGEMENT LLC$10M
- JANE STREET GROUP, LLC$7M
- PRICE T ROWE ASSOCIATES INC /MD/$7M
Institutional holders
One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).
| Fund | Shares | Reported value | % of value | Quarter |
|---|---|---|---|---|
| BlackRock, Inc. added | 5,754,957 | $195M | 6.7% | 2026-Q1 |
| FARALLON CAPITAL MANAGEMENT LLC added | 5,684,000 | $192M | 6.6% | 2026-Q1 |
| STATE STREET CORP added | 3,364,879 | $114M | 3.9% | 2026-Q1 |
| ARMISTICE CAPITAL, LLC trimmed | 2,716,000 | $92M | 3.2% | 2026-Q1 |
| D. E. Shaw & Co., Inc. added | 2,681,169 | $91M | 3.1% | 2026-Q1 |
| VANGUARD CAPITAL MANAGEMENT LLC new | 2,632,316 | $89M | 3.1% | 2026-Q1 |
| Lynx1 Capital Management LP added | 2,611,568 | $88M | 3.1% | 2026-Q1 |
| VANGUARD PORTFOLIO MANAGEMENT LLC new | 2,611,035 | $88M | 3.1% | 2026-Q1 |
| Erste Asset Management GmbH trimmed | 2,704,900 | $80M | 2.8% | 2026-Q1 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. added | 1,580,840 | $53M | 1.8% | 2026-Q1 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. trimmed | 1,494,435 | $51M | 1.7% | 2026-Q1 |
| T. Rowe Price Investment Management, Inc. added | 1,488,740 | $50M | 1.7% | 2026-Q1 |
| GEODE CAPITAL MANAGEMENT, LLC added | 1,467,910 | $50M | 1.7% | 2026-Q1 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP added | 1,344,953 | $45M | 1.6% | 2026-Q1 |
| MPM BIOIMPACT LLC added | 1,306,261 | $44M | 1.5% | 2026-Q1 |
| Frazier Life Sciences Management, L.P. trimmed | 1,256,080 | $42M | 1.5% | 2026-Q1 |
| GW&K Investment Management, LLC added | 1,214,901 | $41M | 1.4% | 2026-Q1 |
| DIMENSIONAL FUND ADVISORS LP added | 1,151,614 | $39M | 1.3% | 2026-Q1 |
| MORGAN STANLEY added | 967,525 | $33M | 1.1% | 2026-Q1 |
| GOLDMAN SACHS GROUP INC trimmed | 805,776 | $27M | 0.9% | 2026-Q1 |
| Rock Springs Capital Management LP | 799,163 | $27M | 0.9% | 2026-Q1 |
| Nuveen, LLC added | 722,348 | $24M | 0.8% | 2026-Q1 |
| JANE STREET GROUP, LLC trimmed | 685,240 | $23M | 0.8% | 2026-Q1 |
| CITADEL ADVISORS LLC trimmed | 619,613 | $21M | 0.7% | 2026-Q1 |
| SCS Capital Management LLC added | 612,850 | $21M | 0.7% | 2026-Q1 |
| WELLINGTON MANAGEMENT GROUP LLP trimmed | 587,142 | $20M | 0.7% | 2026-Q1 |
| Foresite Capital Management VI LLC trimmed | 525,000 | $18M | 0.6% | 2026-Q1 |
| NORTHERN TRUST CORP trimmed | 509,272 | $17M | 0.6% | 2026-Q1 |
| BANK OF AMERICA CORP /DE/ trimmed | 507,900 | $17M | 0.6% | 2026-Q1 |
| Artisan Partners Limited Partnership trimmed | 481,516 | $16M | 0.6% | 2026-Q1 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC trimmed | 477,032 | $16M | 0.6% | 2026-Q1 |
| Connor, Clark & Lunn Investment Management Ltd. trimmed | 450,093 | $15M | 0.5% | 2026-Q1 |
| Vestal Point Capital, LP added | 450,000 | $15M | 0.5% | 2026-Q1 |
| MARSHALL WACE, LLP added | 447,538 | $15M | 0.5% | 2026-Q1 |
| Legal & General Group Plc added | 423,915 | $14M | 0.5% | 2026-Q1 |
| ArrowMark Colorado Holdings LLC trimmed | 403,590 | $14M | 0.5% | 2026-Q1 |
| Parkman Healthcare Partners LLC added | 403,525 | $14M | 0.5% | 2026-Q1 |
| VANGUARD FIDUCIARY TRUST CO new | 382,021 | $13M | 0.4% | 2026-Q1 |
| BNP PARIBAS FINANCIAL MARKETS added | 327,457 | $11M | 0.4% | 2026-Q1 |
| PRICE T ROWE ASSOCIATES INC /MD/ trimmed | 298,783 | $10M | 0.3% | 2026-Q1 |
| KENNEDY CAPITAL MANAGEMENT LLC added | 275,456 | $9M | 0.3% | 2026-Q1 |
| ALGERT GLOBAL LLC trimmed | 268,435 | $9M | 0.3% | 2026-Q1 |
| TWO SIGMA INVESTMENTS, LP trimmed | 251,636 | $9M | 0.3% | 2026-Q1 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP new | 250,461 | $8M | 0.3% | 2026-Q1 |
| PANAGORA ASSET MANAGEMENT INC added | 238,468 | $8M | 0.3% | 2026-Q1 |
| Palo Alto Investors LP added | 213,601 | $7M | 0.2% | 2026-Q1 |
| Seven Fleet Capital Management LP added | 209,547 | $7M | 0.2% | 2026-Q1 |
| Squarepoint Ops LLC added | 208,888 | $7M | 0.2% | 2026-Q1 |
| Schonfeld Strategic Advisors LLC added | 200,061 | $7M | 0.2% | 2026-Q1 |
| Eversept Partners, LP new | 200,000 | $7M | 0.2% | 2026-Q1 |
| HRT FINANCIAL LP added | 195,432 | $7M | 0.2% | 2026-Q1 |
| Qube Research & Technologies Ltd trimmed | 187,667 | $6M | 0.2% | 2026-Q1 |
| Bank of New York Mellon Corp trimmed | 186,791 | $6M | 0.2% | 2026-Q1 |
| GROUP ONE TRADING LLC added | 173,279 | $6M | 0.2% | 2026-Q1 |
| Tetragon Partners GP Ltd added | 164,839 | $6M | 0.2% | 2026-Q1 |
| XTX Topco Ltd added | 160,880 | $5M | 0.2% | 2026-Q1 |
| Invesco Ltd. added | 151,430 | $5M | 0.2% | 2026-Q1 |
| Man Group plc added | 144,297 | $5M | 0.2% | 2026-Q1 |
| Edgestream Partners, L.P. trimmed | 143,731 | $5M | 0.2% | 2026-Q1 |
| ADAR1 Capital Management, LLC trimmed | 140,672 | $5M | 0.2% | 2026-Q1 |
| JPMORGAN CHASE & CO trimmed | 151,558 | $4M | 0.2% | 2026-Q1 |
| UBS Group AG added | 132,540 | $4M | 0.2% | 2026-Q1 |
| CAPITAL FUND MANAGEMENT S.A. added | 129,531 | $4M | 0.2% | 2026-Q1 |
| Exome Asset Management LLC trimmed | 125,060 | $4M | 0.1% | 2026-Q1 |
| AMERICAN CENTURY COMPANIES INC trimmed | 120,253 | $4M | 0.1% | 2026-Q1 |
| Pictet Asset Management Holding SA trimmed | 128,814 | $4M | 0.1% | 2026-Q1 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added | 110,679 | $4M | 0.1% | 2026-Q1 |
| Swiss National Bank | 108,860 | $4M | 0.1% | 2026-Q1 |
| ESSEX INVESTMENT MANAGEMENT CO LLC added | 103,177 | $3M | 0.1% | 2026-Q1 |
| Rafferty Asset Management, LLC trimmed | 102,741 | $3M | 0.1% | 2026-Q1 |
| TANG CAPITAL MANAGEMENT LLC new | 100,000 | $3M | 0.1% | 2026-Q1 |
| Bellevue Group AG added | 3,714,736 | $149M | 5.1% | 2025-Q3 stale |
| VANGUARD GROUP INC trimmed | 5,136,492 | $140M | 4.8% | 2025-Q4 stale |
| Paradigm Biocapital Advisors LP added | 2,673,555 | $107M | 3.7% | 2025-Q3 stale |
| Commodore Capital LP added | 2,338,287 | $94M | 3.2% | 2025-Q3 stale |
| MACQUARIE GROUP LTD added | 1,958,101 | $79M | 2.7% | 2025-Q3 stale |
| Caligan Partners LP added | 1,131,205 | $45M | 1.6% | 2025-Q3 stale |
| Fisher Asset Management, LLC trimmed | 870,145 | $35M | 1.2% | 2025-Q3 stale |
| TCG Crossover Management, LLC trimmed | 1,181,841 | $32M | 1.1% | 2025-Q4 stale |
| ADAGE CAPITAL PARTNERS GP, L.L.C. added | 800,000 | $32M | 1.1% | 2025-Q3 stale |
| Polar Capital Holdings Plc added | 1,002,036 | $29M | 1.0% | 2025-Q1 stale |
| ORBIMED ADVISORS LLC added | 557,900 | $19M | 0.6% | 2025-Q2 stale |
| SummitTX Capital, L.P. added | 262,977 | $11M | 0.4% | 2025-Q3 stale |
| Eagle Health Investments LP trimmed | 246,230 | $10M | 0.3% | 2025-Q3 stale |
| BAKER BROS. ADVISORS LP | 189,866 | $8M | 0.3% | 2025-Q3 stale |
| NORDEA INVESTMENT MANAGEMENT AB added | 224,746 | $8M | 0.3% | 2025-Q2 stale |
| AXA S.A. added | 225,367 | $7M | 0.3% | 2025-Q2 stale |
| AXA Investment Managers S.A. new | 177,675 | $7M | 0.2% | 2025-Q3 stale |
| Cutter Capital Management, LP trimmed | 235,350 | $7M | 0.2% | 2025-Q1 stale |
| PEREGRINE CAPITAL MANAGEMENT LLC trimmed | 162,905 | $7M | 0.2% | 2025-Q3 stale |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC trimmed | 187,395 | $6M | 0.2% | 2025-Q2 stale |
| Alyeska Investment Group, L.P. new | 146,514 | $6M | 0.2% | 2025-Q3 stale |
| Patient Square Capital LP trimmed | 133,827 | $5M | 0.2% | 2025-Q3 stale |
| CANTOR FITZGERALD, L. P. added | 134,200 | $4M | 0.2% | 2025-Q2 stale |
| Walleye Capital LLC trimmed | 150,511 | $4M | 0.2% | 2025-Q1 stale |
| MOORE CAPITAL MANAGEMENT, LP added | 150,000 | $4M | 0.1% | 2025-Q4 stale |
| Allianz Asset Management GmbH added | 147,950 | $4M | 0.1% | 2025-Q4 stale |
| HighVista Strategies LLC trimmed | 147,662 | $4M | 0.1% | 2025-Q4 stale |
| Nantahala Capital Management, LLC new | 100,000 | $4M | 0.1% | 2025-Q3 stale |
| Casdin Capital, LLC trimmed | 100,000 | $3M | 0.1% | 2025-Q2 stale |
Ownership over time
Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.
Reading this table
Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.
About 13F filings
A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.