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Institutional Ownership · SEC Form 13F

Who owns ACAD (ACAD)


Which tracked institutional funds hold ACAD, how they are positioned, and who is buying versus exiting — from SEC Form 13F-HR filings. See ACAD company fundamentals →

Ownership as of the 2026-Q1 13F filings. 13F is disclosed up to 45 days after quarter-end, so the most recent quarter fills in over the following weeks.

340
Institutional holders
159,013,840
Shares held (tracked funds)
93.4%
Of shares outstanding

How the tape is positioned

52 tracked funds added or opened ACAD while 128 trimmed or exited it between 2025-Q4 and 2026-Q1 — the tape is split. When large holders disagree on a name, the funds moving first are sometimes ahead of the story.

A prompt to read the filings, not a verdict. 13F is a quarter-end snapshot disclosed up to 45 days late; a fund adds or exits for mandate, benchmark, and timing reasons that have nothing to do with a view on the stock. This is a starting question, not a signal to trade.

Conviction spread

ACAD’s largest tracked holder by dollar value, BAKER BROS. ADVISORS LP, sizes it at 5.5% of its own reported 13F book, while the median holder sizes it at 0.0% of theirs — a 5.5pp conviction gap — its largest holder concentrates the name more heavily than the typical one.

Book-share is each fund’s reported value in ACAD divided by its whole reported 13F book, so it is comparable across funds of different sizes and is unaffected by stock splits. A higher share means a fund has committed more of its book to the name — a starting question about conviction, not a verdict or a signal to trade.

Institutional & insider positioning

Between 2025-Q4 and 2026-Q1, across 340 tracked filers holding ACAD, 157 increased or opened the position and 170 reduced or closed it; over the same quarter, open-market insider Form 4 buying and selling roughly offset.

This fuses two public signals for the same quarter — how tracked institutions changed their positions and whether insiders bought or sold in the open market. It describes what was filed; it is a starting question, not a verdict or a signal to trade.

New buyers & exits

Funds opening or closing a position in ACAD between the 2025-Q4 and 2026-Q1 13F filings, and the largest changes among funds holding it in both. New buyers and exits are counted on fund presence (split-invariant); adds and trims are measured on reported value.

New buyers 27

  • VANGUARD PORTFOLIO MANAGEMENT LLC$193M
  • VANGUARD CAPITAL MANAGEMENT LLC$126M
  • Artisan Partners Limited Partnership$30M
  • VANGUARD FIDUCIARY TRUST CO$19M
  • JANE STREET GROUP, LLC$18M
  • Woodline Partners LP$15M

Full exits 14

  • VANGUARD GROUP INC$377M
  • Trails Edge Capital Partners, LP$38M
  • TWO SIGMA ADVISERS, LP$10M
  • TANG CAPITAL MANAGEMENT LLC$8M
  • DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main$5M
  • Eversept Partners, LP$5M

Largest adds

  • FIRST TRUST ADVISORS LP$14M
  • Hudson Bay Capital Management LP$8M
  • Allianz Asset Management GmbH$8M
  • Squarepoint Ops LLC$7M
  • Allspring Global Investments Holdings, LLC$4M
  • BESSEMER GROUP INC$3M

Largest trims

  • BlackRock, Inc.$231M
  • BAKER BROS. ADVISORS LP$191M
  • Point72 Asset Management, L.P.$33M
  • RTW INVESTMENTS, LP$32M
  • STATE STREET CORP$26M
  • CITADEL ADVISORS LLC$23M

Institutional holders

One row per tracked fund, largest reported value first. “% of value” is the fund’s share of this security’s tracked institutional value — not of shares outstanding. Rows marked stale are from an earlier filing than the security’s latest quarter — that fund is absent from the newest snapshot (position exited, or reported under a different name).

FundSharesReported value% of valueQuarter
BAKER BROS. ADVISORS LP42,896,690$955M24.8%2026-Q1
BlackRock, Inc. trimmed14,516,607$323M8.4%2026-Q1
VANGUARD PORTFOLIO MANAGEMENT LLC new8,671,645$193M5.0%2026-Q1
STATE STREET CORP added8,332,771$185M4.8%2026-Q1
RTW INVESTMENTS, LP7,144,524$159M4.1%2026-Q1
VANGUARD CAPITAL MANAGEMENT LLC new5,661,400$126M3.3%2026-Q1
GEODE CAPITAL MANAGEMENT, LLC added3,464,689$77M2.0%2026-Q1
FIRST TRUST ADVISORS LP added3,343,868$74M1.9%2026-Q1
DIMENSIONAL FUND ADVISORS LP added3,155,160$70M1.8%2026-Q1
Palo Alto Investors LP added2,872,695$64M1.7%2026-Q1
Point72 Asset Management, L.P. trimmed2,577,916$57M1.5%2026-Q1
BRAIDWELL LP added2,471,199$55M1.4%2026-Q1
Pictet Asset Management Holding SA added2,026,044$45M1.2%2026-Q1
RENAISSANCE TECHNOLOGIES LLC added1,724,196$38M1.0%2026-Q1
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP added1,569,491$35M0.9%2026-Q1
GOLDMAN SACHS GROUP INC trimmed1,557,804$35M0.9%2026-Q1
BANK OF AMERICA CORP /DE/ added1,553,770$35M0.9%2026-Q1
Frazier Life Sciences Management, L.P. added1,438,198$32M0.8%2026-Q1
Artisan Partners Limited Partnership added1,331,813$30M0.8%2026-Q1
FRED ALGER MANAGEMENT, LLC trimmed1,277,151$28M0.7%2026-Q1
NORTHERN TRUST CORP added1,272,611$28M0.7%2026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INC added1,173,560$26M0.7%2026-Q1
MORGAN STANLEY trimmed1,093,151$24M0.6%2026-Q1
NORGES BANK trimmed1,420,611$24M0.6%2026-Q1
Nuveen, LLC trimmed1,036,987$23M0.6%2026-Q1
Rockefeller Capital Management L.P. trimmed1,027,357$23M0.6%2026-Q1
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ trimmed1,019,824$23M0.6%2026-Q1
Allspring Global Investments Holdings, LLC added954,855$21M0.6%2026-Q1
Qube Research & Technologies Ltd trimmed950,299$21M0.5%2026-Q1
VANGUARD FIDUCIARY TRUST CO new875,720$19M0.5%2026-Q1
DEUTSCHE BANK AG\ added840,414$19M0.5%2026-Q1
JANE STREET GROUP, LLC added803,265$18M0.5%2026-Q1
TWO SIGMA INVESTMENTS, LP trimmed775,121$17M0.4%2026-Q1
PRINCIPAL FINANCIAL GROUP INC added768,224$17M0.4%2026-Q1
Logos Global Management LP trimmed750,000$17M0.4%2026-Q1
Bank of New York Mellon Corp trimmed736,558$16M0.4%2026-Q1
Invesco Ltd. trimmed735,915$16M0.4%2026-Q1
Fisher Asset Management, LLC added732,872$16M0.4%2026-Q1
D. E. Shaw & Co., Inc. trimmed729,836$16M0.4%2026-Q1
Allianz Asset Management GmbH added706,664$16M0.4%2026-Q1
MILLENNIUM MANAGEMENT LLC added705,461$16M0.4%2026-Q1
PANAGORA ASSET MANAGEMENT INC added688,649$15M0.4%2026-Q1
Woodline Partners LP added676,401$15M0.4%2026-Q1
PRICE T ROWE ASSOCIATES INC /MD/ added634,662$14M0.4%2026-Q1
AMERIPRISE FINANCIAL INC trimmed624,260$14M0.4%2026-Q1
CITADEL ADVISORS LLC trimmed622,760$14M0.4%2026-Q1
RICE HALL JAMES & ASSOCIATES, LLC added617,489$14M0.4%2026-Q1
VOYA INVESTMENT MANAGEMENT LLC trimmed613,784$14M0.4%2026-Q1
MANUFACTURERS LIFE INSURANCE COMPANY, THE added571,776$13M0.3%2026-Q1
AQR CAPITAL MANAGEMENT LLC trimmed515,958$11M0.3%2026-Q1
JUPITER ASSET MANAGEMENT LTD trimmed491,093$11M0.3%2026-Q1
UBS Group AG trimmed448,549$10M0.3%2026-Q1
Public Sector Pension Investment Board added447,930$10M0.3%2026-Q1
Hudson Bay Capital Management LP added445,506$10M0.3%2026-Q1
GLENMEDE TRUST CO NA trimmed405,892$9M0.2%2026-Q1
PRUDENTIAL FINANCIAL INC trimmed387,650$9M0.2%2026-Q1
Squarepoint Ops LLC added370,458$8M0.2%2026-Q1
RHUMBLINE ADVISERS trimmed355,461$8M0.2%2026-Q1
FMR LLC trimmed349,450$8M0.2%2026-Q1
BALYASNY ASSET MANAGEMENT L.P. trimmed312,982$7M0.2%2026-Q1
Connor, Clark & Lunn Investment Management Ltd. trimmed294,265$7M0.2%2026-Q1
Legal & General Group Plc trimmed287,382$6M0.2%2026-Q1
SPHERA FUNDS MANAGEMENT LTD. added256,202$6M0.1%2026-Q1
JPMORGAN CHASE & CO trimmed263,091$6M0.1%2026-Q1
LAZARD ASSET MANAGEMENT LLC added246,297$5M0.1%2026-Q1
STEMPOINT CAPITAL LP new242,566$5M0.1%2026-Q1
GREAT LAKES ADVISORS, LLC trimmed241,827$5M0.1%2026-Q1
Trexquant Investment LP trimmed235,946$5M0.1%2026-Q1
Swiss National Bank added234,404$5M0.1%2026-Q1
FRANKLIN RESOURCES INC added230,072$5M0.1%2026-Q1
ROYAL BANK OF CANADA trimmed223,155$5M0.1%2026-Q1
NORDEA INVESTMENT MANAGEMENT AB trimmed228,125$5M0.1%2026-Q1
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC added206,884$5M0.1%2026-Q1
Edgestream Partners, L.P. trimmed191,328$4M0.1%2026-Q1
Rafferty Asset Management, LLC trimmed181,676$4M0.1%2026-Q1
ALLIANCEBERNSTEIN L.P. trimmed149,327$4M0.1%2026-Q1
Birchview Capital, LP171,000$4M0.1%2026-Q1
ENVESTNET ASSET MANAGEMENT INC added169,954$4M0.1%2026-Q1
HUSSMAN STRATEGIC ADVISORS, INC. added168,000$4M0.1%2026-Q1
ALPS ADVISORS INC added162,820$4M0.1%2026-Q1
CONGRESS ASSET MANAGEMENT CO new160,794$4M0.1%2026-Q1
STATE OF WISCONSIN INVESTMENT BOARD added156,422$3M0.1%2026-Q1
NEW YORK STATE COMMON RETIREMENT FUND added153,053$3M0.1%2026-Q1
Axecap Investments, LLC added152,910$3M0.1%2026-Q1
BESSEMER GROUP INC added150,498$3M0.1%2026-Q1
Tetragon Partners GP Ltd added144,620$3M0.1%2026-Q1
VICTORY CAPITAL MANAGEMENT INC trimmed143,469$3M0.1%2026-Q1
JACOBS LEVY EQUITY MANAGEMENT, INC trimmed142,716$3M0.1%2026-Q1
Bridgewater Associates, LP added141,812$3M0.1%2026-Q1
ALGERT GLOBAL LLC trimmed140,462$3M0.1%2026-Q1
VANGUARD GROUP INC trimmed14,113,391$377M9.8%2025-Q4 stale
Trails Edge Capital Partners, LP new1,419,406$38M1.0%2025-Q4 stale
EVENTIDE ASSET MANAGEMENT, LLC trimmed575,541$12M0.3%2025-Q3 stale
Candriam S.C.A. added537,601$11M0.3%2025-Q3 stale
TWO SIGMA ADVISERS, LP added370,200$10M0.3%2025-Q4 stale
TANG CAPITAL MANAGEMENT LLC trimmed300,000$8M0.2%2025-Q4 stale
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main added194,146$5M0.1%2025-Q4 stale
Eversept Partners, LP added176,594$5M0.1%2025-Q4 stale
Schonfeld Strategic Advisors LLC added199,024$4M0.1%2025-Q2 stale
J. Goldman & Co LP added164,278$4M0.1%2025-Q2 stale

Ownership over time

Tracked institutional holder count and total shares held by filing quarter (independent scales). The curated-era tail and any mid-ingest latest quarter are handled honestly — a partial quarter is not drawn as a collapse.

HoldersTotal shares

Reading this table

Funds hold the same stock for different reasons — an index fund “holds” almost everything, an active manager sizes a name to a mandate and a benchmark, and each fund entered at its own price and time. Because 13F is filed up to 45 days after quarter-end, every row is a backward-looking snapshot; a manager may have traded since. Share-class siblings (a company’s A and C shares) are rolled up to one line so a dual-class name is never double-counted. Compare like-for-like. A large holder is not an endorsement, and a fund exiting is not a warning — this is a starting question, not a verdict.

About 13F filings

A Form 13F is a quarterly disclosure that institutional investment managers with over $100 million in US-listed equities must file with the SEC. In plain English: it is a snapshot of the long stock positions a fund held at the end of a quarter. It covers long US-listed equities only — not short positions, options, cash, or private holdings — and the funds shown are the large sample we track, not the complete 13F universe.

Learn how to read institutional ownership